Category: 80-09-1

Liu, Qian published the artcileThree-dimensional (3D) thermal controlled polymer for simplified dispersive liquid-liquid microextraction in phthalic acid easters detection of straw, Category: alcohols-buliding-blocks, the publication is Microchemical Journal (2022), 107668, database is CAplus.

In this paper, a three-dimensional (3D) polyfunctional group and thermal controlled polymer p(POSS-co-DMAEMA) was prepared based on the chem. structure of the phthalic acid easters (PAEs) and applied as an extractant for dispersive liquid-liquid microextraction (DLLME) in combination with HPLC-UV. The polymer with good biocompatibility can be dispersed and aggregated by shaking and heating based on the thermal controlled properties without the assistance of instruments, which shortened the DLLME process as low as 5 min. The feasibility of the developed method was verified using 5 PAEs as targets in simulated water samples, which showed good precision (RSD%, 1.3-10.0, n = 3) and low detection limit (0.19-0.52 ng mL-1) under the optimal extraction conditions. This proposed method was successfully applied in analyzing four straws and good spiked recoveries over the range of 91.60-128.00% were obtained. Furthermore, mol. docking was employed to explore the mol. interactions and calculate binding energies between the polymer and organic pollutants, ensuring the synthesized polymer has a strong extraction ability for PAEs. The satisfied extraction efficiency can be attributed to the fact that the p(POSS-co-DMAEMA) is water-soluble at room temperature but hydrophobic at high temperature, and the high extraction ability can be achieved by the strong intermol. forces between the polymer and PAEs. The exptl. results suggest that the proposed method holds good promise for the trace anal. of PAEs.

Microchemical Journal published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Owczarek, Katarzyna published the artcileValidated GC-MS method for determination of bisphenol a and its five analogues in dietary and nutritional supplements, SDS of cas: 80-09-1, the publication is Microchemical Journal (2022), 107643, database is CAplus.

Bisphenol A (BPA) and its analogs showing structural and functional similarity to BPA are commonly applied in various industrial applications and thus are becoming ubiquitous in the environment. At the same time there is increasing scientific evidence that exposure to these chems. may lead to adverse health effects in human and wildlife. In recent years dietary and nutritional supplements dedicated for athletes have become more popular and are widely used even by people who are not professionals. This study presents the development, optimization and validation of an anal. procedure for determination of six bisphenol analogs in dietary supplements using gas chromatog. – mass spectrometry technique. All validation parameters met the established acceptance criteria in accordance with international guidelines. The method was linear within the tested range of 50-1000 ng/mL, the limit of quantitation was set as the lowest calibration point 50 ng/mL, detection limit for each bisphenol was calculated as standard estimation error on the basis of the linearity testing and was in the range of 8.73-15.44 ng/mL. Method trueness, accuracy (within and between runs) and precision were also verified and were in the range of 78.8 – 100.4%, 94.3 – 103.1%,0.5 – 9.6% resp. The developed procedure was successfully applied for real samples anal., namely for fifteen sport supplements of different composition and designated for various purposes, i.e. for increasing effectiveness, promoting muscle recovery and endurance, reducing tiredness and fatigue or increasing immune ability. For the majority of samples, bisphenols were either not detected or detected at the LOD level except bisphenol A which was quantitated in few samples at LOQ level or higher (in the range 0.852-2.892 ng/mg). The field of bisphenol analogs analytics has increased in recent years due to law regulations becoming more strict, thus the development of new anal. tools for quality control of dietary products is needed and fully justified.

Microchemical Journal published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, SDS of cas: 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ao, Junjie published the artcilePatterns of environmental exposure to phenols in couples who plan to become pregnant, Category: alcohols-buliding-blocks, the publication is Science of the Total Environment (2022), 153520, database is CAplus and MEDLINE.

Phenols are widely used in consumer products and known for their reproductive toxicities. Little is known regarding the environmental exposure to phenols in couples prior to conception, a key period affecting fertility. We measured the urinary concentrations of six parabens and seven bisphenols in 903 pre-conception couples in China. We investigated the occurrence, distribution, source and health risk of phenols in husbands and wives sep., and the correlation and difference in phenol concentrations between couples. Similar distribution profiles of urinary phenols were observed between females and males. Me 4-hydroxybenzoate (MeP) and bisphenol A (BPA) were the predominant compounds The level of urinary phenols in our population was mostly lower than the global levels. Exposure to phenols was linked to processed food and personal care products. The correlations between phenols in males and females were moderate (0.218-0.686), while the correlation in phenols between husband and wife was low (0.009-0.215). Female had a significantly higher urinary phenol levels than male (P < 0.05). Urinary phenols in couples were associated with family income, type of drinking water and frequency of household cleaning. Household factors accounted for ≤1.5% of variance in phenol levels between couples, suggesting that individual variations may be the major factor. Risk assessment showed that exposure to phenols posed a low hazard to 17.5% of the couples in our population. Our findings provide important evidence of environmental exposure to phenols in couples of child-bearing age.

Science of the Total Environment published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Aimuzi, Ruxianguli published the artcileExposure to phthalates, phenols, and parabens mixture and alterations in sex steroid hormones among adolescents, Recommanded Product: 4,4′-Sulfonyldiphenol, the publication is Chemosphere (2022), 134834, database is CAplus and MEDLINE.

Exposure to phthalates (PAEs), phenols, and parabens has been linked with sex hormone imbalance; however, previous studies were predominantly limited to adults and failed to examine the combined effects of these chems. mixture among adolescents. Thus, we used the data from the National Health and Nutrition Examination Survey (2013-2016) to explore the associations of urinary PAEs, phenols, and parabens biomarkers with sex hormones among participants aged 12-19 years old (n = 613). Latent class anal. (LCA) and quantile-based g-computation (QGC) were applied to assess the associations of the latent exposure profiles and chems. mixture with sex hormone indicators, including steroid hormones and sex hormone binding globulin (SHBG), in adolescents and by sex. Using LCA, four latent classes were identified among all participants. Compared with the class characterized by “Low exposure”, the class represented by “High PAEs” [mono (2-ethyl-5-carboxypentyl) phthalate (MECPP), mono (2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), and monobenzyl phthalate (MBZP)] had lower level of estradiol (E2) [β = -0.249, 95% confidence interval (CI): -0.419, -0.08], free androgen index (FAI) (β = -0.258, 95%CI: -0.512, -0.005) and free testosterone (FT) (β = -0.248, 95%CI: -0.496, -0.001) among male adolescents. These results were echoed by the results in QGC analyses, where PAEs mixture was neg. associated with E2 (β = -0.137, 95% CI: -0.263, -0.011), FAI (β = -0.198, 95%CI: -0.387, -0.008) and FT (β = -0.189, 95%CI: -0.375, -0.002) among male adolescents. By contrast, the associations of the identified latent classes or chems. mixture with sex hormone indicators were generally nonsignificant among female counterparts, except for a pos. association between PAEs mixture and SHBG (β = 0.121, 95%CI: 0.012, 0.23). Our study demonstrated that exposure to PAEs, particularly MECPP, MEHHP, and MBZP, would be a threat to the sex hormone homeostasis of male adolescents.

Chemosphere published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Recommanded Product: 4,4′-Sulfonyldiphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Pang, Yue-Hong published the artcileCovalent organic framework modified carbon cloth for ratiometric electrochemical sensing of bisphenol A and S, HPLC of Formula: 80-09-1, the publication is Microchimica Acta (2022), 189(5), 189, database is CAplus and MEDLINE.

A novel ratiometric electrochem. sensor was developed based on a carbon cloth electrodeposited with silver nanoparticles and drop-coated by covalent organic framework (COF-LZU1) for simultaneous determination of bisphenol A (BPA) and bisphenol S (BPS). Carbon cloth exhibited a significantly larger electrochem. active area than common glassy carbon electrodes (27.5 times). Silver nanoparticles not only provided a stable reference signal but also enhanced electroactivity for the oxidation of BPA and BPS. COF-LZU1 with good adsorption performance and large periodic π-arrays promoted the enrichment of BPA and BPS to further increase the current response. Compared with the traditional single-signal electrochem. sensor, the developed ratiometric sensor exhibited better reproducibility and a wider linear range for BPA and BPS from 0.5 to 100μM with a limit of detection of 0.15μM. Furthermore, the developed sensor showed excellent stability and superior anti-interference ability. The real sample anal. for BPA and BPS has been successfully carried out in mineral water, electrolyte drink, tea, juice, and beer with recoveries of 88.3-111.7%. The developed ratiometric sensor is expected to be a candidate for the preparation of other electrochem. sensors and the anal. of addnl. practical samples.

Microchimica Acta published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, HPLC of Formula: 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhao, C. published the artcileRemoval of bisphenol S from drinking water by adsorption using activated carbon and the mechanisms involved, Quality Control of 80-09-1, the publication is International Journal of Environmental Science and Technology (2022), 19(6), 5289-5300, database is CAplus.

Bisphenol S, an alternative chem. to bisphenol A, has a neg. effect on living organisms and has frequently been detected in drinking water systems. A promising and cost-effective method for removing bisphenol S from tap water is adsorption by activated carbon. However, activated carbon significantly decreased the adsorption capacity of bisphenol S in tap water comparing with that in deionized water based on the exptl. results. Dissolved organic matter in tap water was likely responsible for it. The adsorption kinetics can be described by a pseudo-second-order model. The Langmuir isotherm model can well describe the process, suggesting monolayer adsorption. The maximum adsorption capacity was calculated as 83.19 mg g^-1. Higher temperature and pH were unfavorable to the process. Changes in entropy, enthalpy, and Gibbs free energy were calculated and implied a spontaneous and exothermic adsorption process. Fourier transform IR spectroscopic anal. found that hydroxyl and amino functional groups are the main groups involved. The research provides a substantial basis for understanding bisphenol S removal from drinking water by adsorption using activated carbon to limit direct exposure to bisphenol S in drinking water.

International Journal of Environmental Science and Technology published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C18H23OP, Quality Control of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yang, Pan published the artcileExposure profiles and predictors of a cocktail of environmental chemicals in Chinese men of reproductive age, Formula: C12H10O4S, the publication is Chemosphere (2022), 134337, database is CAplus and MEDLINE.

Personal care products, such as additives, have raised widespread concerns about the potential threat to male reproductive health. The spermatogenesis in humans lasts for approx. 90 days, the average levels of these chems. remain unclear during spermatogenesis. In our study, we pooled urine samples from each man during the days of 1-15, 16-31, 32-63, and ≥64, and examined exposure to 48 typical additive chems. By principal component anal. (PCA), k-means clustering, and Spearman’s rank correlations, we then identified 6 PC scores and 4 clusters based on profiles of these chems. Some industrial, com. or structural similar chems. (e.g., phthalates) were significantly correlated compared to unrelated chems. (e.g., benzophenone). PCA scores were associated with individual lifestyles (e.g., household income, tea consumption, and drinking tap water). Distinct exposure components and exposure patterns of personal care products may help the reproductive health assessment of men. We suggested more concerns for widespread exposure to these chems. for men.

Chemosphere published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C8H10O2, Formula: C12H10O4S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Musachio, Elize Aparecida Santos published the artcileSex-specific changes in oxidative stress parameters and longevity produced by Bisphenol F and S compared to Bisphenol A in Drosophila melanogaster, Name: 4,4′-Sulfonyldiphenol, the publication is Comparative Biochemistry and Physiology, Part C: Toxicology & Pharmacology (2022), 109329, database is CAplus and MEDLINE.

Female and male Drosophila melanogaster were exposed sep. for seven days to Bisphenol A (BPA), Bisphenol F (BPF), and Bisphenol S (BPS) at concentrations of 0.25, 0.5, and 1 mM. We observed that males exposed to 0.5 and 1 mM BPS showed lower catalase (CAT) activity and higher superoxide dismutase (SOD) and reactive species (RS); CAT activity decreased for BPF 0.5 and 1 mM. Nevertheless, BPA 0.5 and 1 mM decreased CAT activity, increased RS and lipid peroxidation (LPO), and reduced mitochondrial viability. None of the bisphenols altered the cell viability of male flies, although BPA 0.5 and 1 mM reduced longevity. In female flies, BPA and BPS 0.5 and 1 mM increased RS and LPO levels and decreased CAT activity and glutathione-S-transferase (GST), which may have contributed to lower mitochondrial and cell viability. Furthermore, BPS decreased SOD activity at the 1 mM concentration, and BPA reduced the SOD activity at concentrations of 0.5 and 1 mM. In the BPF 1 mM group, there was a reduction in GST activity and an increase in RS and LPO levels. The toxicol. effects were different between sexes, and BPA was more harmful than BPF and BPS in male flies. Thus, our findings showed that females were more susceptible to oxidative cell damage when exposed to BPA and BPS than to BPF, and daily exposure to BPA and BPS at all concentrations reduced female longevity, as well as in BPF 1 mM.

Comparative Biochemistry and Physiology, Part C: Toxicology & Pharmacology published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Name: 4,4′-Sulfonyldiphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lee, Handule published the artcileEffects of consumer products chemicals ingredients and their mixtures on the estrogen receptor/androgen receptor transcriptional activation, Recommanded Product: 4,4′-Sulfonyldiphenol, the publication is Chemosphere (2022), 134866, database is CAplus and MEDLINE.

Unlike the environmental pollutants or industrial chems., the chems. in consumer products may pose higher levels of risks, depending on how the chems. are used in the products and how humans interact with the products. Recently, endocrine disrupting chems. in cosmetics, personal care products, cleaners, sunscreens, and vinyl products were anal. quantified and many active chems. including phthalates, parabens and bisphenols were detected. This indicates a wide range of exposures from common products. In this study, 35 chems. known to be ingredients of consumer products were selected and screened for the transactivation of estrogen receptors and androgen receptors. From the results of individual chems., the activity of binary/ternary mixture prepared from the agonists for the ER transcription activity was measured, and compared to the predicted values obtained by the full logistic model. The measured and the predicted values were found to be very similar. This study may suggest that prediction of mixture activity by proper models would be one of the supportive tools for the risk assessment and sound regulation of chem. mixtures which have potential endocrine disrupting effects in consumer products.

Chemosphere published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Recommanded Product: 4,4′-Sulfonyldiphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hu, Peipei published the artcileAssociations between exposure to a mixture of phenols, parabens, and phthalates and sex steroid hormones in children 6-19 years from NHANES, 2013-2016, COA of Formula: C12H10O4S, the publication is Science of the Total Environment (2022), 153548, database is CAplus and MEDLINE.

Humans are typically exposed to mixtures of environmental endocrine-disrupting chems. simultaneously, but most studies have considered only a single chem. or a class of similar chems. We examined the association of exposure to mixtures of 7 chems., including 2 phenols [bisphenol A (BPA) and bisphenol S (BPS)], 2 parabens [methylparaben (MeP) and Pr paraben (PrP)], and 3 phthalate metabolites [Mono-benzyl phthalate (MBzP), mono-iso-Bu phthalate (MiBP), mono (carboxyoctyl) phthalate (MCOP)] with sex steroid hormones. A total of 1179 children aged 6-19 years who had complete data on both 7 chems. and sex steroid hormones of estradiol (E2), total testosterone (TT), and sex hormone-binding globulin (SHBG) were analyzed from the U. S. National Health and Nutrition Examination Survey 2013-2016. Free androgen index (FAI) calculated by TT/SHBG, and the ratio of TT to E2 (TT/E2) were also estimated Puberty was defined if TT ≥ 50 ng/dL in boys, E2 ≥ 20 pg/mL in girls; otherwise prepuberty was defined. Linear regression, weighted quantile sum (WQS) regression, and Bayesian kernel machine regression (BKMR) were performed to estimate the associations of individual chem. or chem. mixtures with sex hormones. The linear regression showed that 2 phenols, 2 parabens, and 3 phthalate metabolites were generally neg. associated with E2, TT, FAI, and TT/E2, while pos. with SHBG. Moreover, these associations were more pronounced among pubertal than prepubertal children. The aforementioned associations were confirmed when further applying WQS and BKMR, and the 3 phthalates metabolites were identified to be the most heavily weighing chems. Exposure to phenols, parabens, and phthalates, either individuals or as a mixture, was neg. associated with E2, TT, FAI and TT/E2, while pos. with SHBG. Those associations were stronger among pubertal children.

Science of the Total Environment published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, COA of Formula: C12H10O4S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts