Category: 79418-41-0

Electric Literature of 79418-41-0, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 79418-41-0, name is 3-Amino-7-hydroxy-2H-chromen-2-one, molecular formula is C9H7NO3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

3-Amino-7-hydroxy-2H-chromen-2-one (3) (0.56 g, 31 mmol) and O-(4-formylphenyl)dimethylcarbamothioate (0.65 g, 31 mmol) were dissolved in absoluteEtOH (10 mL) and refluxed for 2 h, during which time a precipitate formed.After cooling, the solid was collected and washed with an excess of hot EtOH:yellow solid, 0.85 g, 80 %. m.p. 240-242 C; 1H NMR (DMSO-d6): delta 8.59 (s, 1H, N=C-Ar), 7.94-7.92 (d, 1H, Ar-H, J = 8.6 Hz), 7.78 (s, 1H, =C-H),7.56-7.54 (d, 1H, Ar-H, J = 8.0 Hz),7.22-7.20 (d, 1H, Ar-H, J = 8.0 Hz),6.81 (dd, 1H, Ar-H, J = 8.0, 2.0 Hz),6.75(d, 1H, Ar-H, J = 2.0 Hz), 3.36(s, 3H, N(CH3)2), 3.32 (s, 3H, N(CH3)2);13C NMR (DMSO-d6):delta 39.1, 43.3, 102.3, 112.4, 114.0, 123.9, 130.0, 130.1, 132.3, 132.4, 133.8,154.0, 156.7, 158.5, 161.1, 161.8, 186.3; m/z obsd 369.0895; calcd for [M+H]+369.4143.

According to the analysis of related databases, 79418-41-0, the application of this compound in the production field has become more and more popular.

Reference:
Article; Garcia-Beltran, Olimpo; Rodriguez, Alejandra; Trujillo, Ariel; Canete, Alvaro; Aguirre, Pabla; Gallego-Quintero, Sebastian; Nunez, Marco T.; Aliaga, Margarita E.; Tetrahedron Letters; vol. 56; 42; (2015); p. 5761 – 5766;,
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The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 79418-41-0, name is 3-Amino-7-hydroxy-2H-chromen-2-one. This compound has unique chemical properties. The synthetic route is as follows. Quality Control of 3-Amino-7-hydroxy-2H-chromen-2-one

General procedure: To a solution of 3-amino 7-hydroxycoumarin (1.0 eq) in dimethylformamide (DMF) (20 mL) was added anhy. K2CO3 (2.5 eq) and stirredat room temperature for 10-15 min. To this mixture, alkyl bromide(1.0 mmol) was added and resulting solution was stirred at room temperature(rt) for 22-24 h. The completion of reaction was checked byTLC. After completion of reaction, the reaction mixture was pouredinto ice-cold water to give solid. The solid was filtered, washed withwater, dried and recrystallized from ethanol to give compound 13 asoffwhite solid. These compounds 14a-lwere directly used for next step.

With the rapid development of chemical substances, we look forward to future research findings about 79418-41-0.

Reference:
Article; Durgapal, Sunil Dutt; Soni, Rina; Soman, Shubhangi S.; Prajapati; Journal of Molecular Liquids; vol. 297; (2020);,
Alcohol – Wikipedia,
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With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.79418-41-0, name is 3-Amino-7-hydroxy-2H-chromen-2-one, molecular formula is C9H7NO3, molecular weight is 177.1568, as common compound, the synthetic route is as follows.Recommanded Product: 79418-41-0

A portion of 7-diethylaminocoumarin-3-aldehyde (247 mg, 1 mmol) and 3-amino-7-hydroxycoumarin (195 mg, 1.1 mmol) were combined in hot absolute ethanol (20 mL) to yield a scarlet precipitate for a moment. The solution was stirred under reflux conditions for 6 h, and the precipitate was filtrated, washed with hot absolute ethanol three times, then recrystallized with DMF/H2O (v/v, 1/3) to get scarlet crystal L (347 mg, 0.86 mmol) in 86% yield. IR (KBr, cm-1): 2966, 2927, 1718, 1620, 1349, 1506, 1456, 1420, 845, 811, 770, 729, 693. 1H NMR (DMSO-d6, 400 MHz, delta): 10.54(s, 1H, OH), 9.04(s, 1H, NCH), 8.56(s, 1H, ArH), 7.81(s, 1H, ArH), 7.70(d, 1H, J = 12 Hz, ArH), 7.58(d, 1H, J = 8 Hz, ArH), 6.81 (t, 1H, J = 8 Hz, ArH), 6.77 (s, 1H, ArH), 6.61(s, 1H, ArH), 3.49(q, 4H, J = 8 Hz, CH2CH3), 1.16(t, 6H, J = 8 Hz, CH2CH3). Anal. Calcd for C23H20N2O5: C 68.31%, H 4.98%, N 6.93%, Found: C 68.55%, H 5.04%, N 6.66%.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,79418-41-0, 3-Amino-7-hydroxy-2H-chromen-2-one, and friends who are interested can also refer to it.

Reference:
Article; Wang, Lingyun; Ye, Decheng; Cao, Derong; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 90; (2012); p. 40 – 44;,
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Alcohols – Chemistry LibreTexts

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 79418-41-0, name is 3-Amino-7-hydroxy-2H-chromen-2-one. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C9H7NO3

General procedure: To a solution of 3-amino 7-hydroxycoumarin (1.0 eq) in dimethylformamide (DMF) (20 mL) was added anhy. K2CO3 (2.5 eq) and stirredat room temperature for 10-15 min. To this mixture, alkyl bromide(1.0 mmol) was added and resulting solution was stirred at room temperature(rt) for 22-24 h. The completion of reaction was checked byTLC. After completion of reaction, the reaction mixture was pouredinto ice-cold water to give solid. The solid was filtered, washed withwater, dried and recrystallized from ethanol to give compound 13 asoffwhite solid. These compounds 14a-lwere directly used for next step.

With the rapid development of chemical substances, we look forward to future research findings about 79418-41-0.

Reference:
Article; Durgapal, Sunil Dutt; Soni, Rina; Soman, Shubhangi S.; Prajapati; Journal of Molecular Liquids; vol. 297; (2020);,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Adding a certain compound to certain chemical reactions, such as: 79418-41-0, 3-Amino-7-hydroxy-2H-chromen-2-one, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 79418-41-0, blongs to alcohols-buliding-blocks compound. COA of Formula: C9H7NO3

General procedure: 3-Amino-7-hydroxy-2H-chromen-2-one (0.56 g, 31 mmol) and the appropriate benzaldehyde (31 mmol) were dissolved in absolute EtOH (10 mL) and refluxed for 2 h. The precipitate formed was collected and washed with hot EtOH. In this way, the following (E)-7-hydroxy-3-(benzylidenimino)- 2H-chromen-2-ones 1-6 were prepared.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,79418-41-0, its application will become more common.

Reference:
Article; Nunez, Carolina; Morales, Nicole; Garcia-Beltran, Olimpo; Mascayano, Carolina; Fierro, Angelica; Medicinal Chemistry Research; vol. 26; 11; (2017); p. 2707 – 2717;,
Alcohol – Wikipedia,
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Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 79418-41-0, name is 3-Amino-7-hydroxy-2H-chromen-2-one. This compound has unique chemical properties. The synthetic route is as follows. name: 3-Amino-7-hydroxy-2H-chromen-2-one

General procedure: To a solution of 3-amino 7-hydroxycoumarin (1.0 eq) in dimethylformamide (DMF) (20 mL) was added anhy. K2CO3 (2.5 eq) and stirredat room temperature for 10-15 min. To this mixture, alkyl bromide(1.0 mmol) was added and resulting solution was stirred at room temperature(rt) for 22-24 h. The completion of reaction was checked byTLC. After completion of reaction, the reaction mixture was pouredinto ice-cold water to give solid. The solid was filtered, washed withwater, dried and recrystallized from ethanol to give compound 13 asoffwhite solid. These compounds 14a-lwere directly used for next step.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 79418-41-0, 3-Amino-7-hydroxy-2H-chromen-2-one.

Reference:
Article; Durgapal, Sunil Dutt; Soni, Rina; Soman, Shubhangi S.; Prajapati; Journal of Molecular Liquids; vol. 297; (2020);,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthetic Route of 79418-41-0, Adding some certain compound to certain chemical reactions, such as: 79418-41-0, name is 3-Amino-7-hydroxy-2H-chromen-2-one,molecular formula is C9H7NO3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 79418-41-0.

3-Amino-7-hydroxy-2H-chromen-2-one (3) (0.56 g, 31 mmol) and 2,5-dimethoxybenzaldehyde (0.51 g, 31 mmol) were dissolved in absolute EtOH (10 mL) and refluxed for 2 h, during which time a precipitate formed. After cooling, the solid was collected and washed with an excess of hot EtOH: yellow solid, 0.9 g, 89 %. m.p. 206-208 C; 1H NMR (DMSO-d6): delta 10.53 (br s, 1H, O-H), 9.31 (s, 1H, N=C-Ar), 7.81 (s, 1H, =C-H), 7.54 (d, 1H, Ar-H, J = 8.2 Hz) 7.50 (s, 2H, Ar-H), 7.09 (s, 2H, Ar-H), 6.80 (d, 1H, Ar-H, J = 8.2 Hz), 6.74 (s, 1H, Ar-H), 3.83 (s, 3H, OCH3), 3.75 (s, 3H, OCH3). m/z obsd 348.1154; calcd for C18H15NO5Na 348.08479.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 79418-41-0, 3-Amino-7-hydroxy-2H-chromen-2-one, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Garcia-Beltran, Olimpo; Mena, Natalia; Friedrich, Leidi C.; Netto-Ferreira, Jose Carlos; Vargas, Victor; Quina, Frank H.; Nunez, Marco T.; Cassels, Bruce K.; Tetrahedron Letters; vol. 53; 39; (2012); p. 5280 – 5283;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts