Sawano, Takahiro’s team published research in Chemical Communications (Cambridge, United Kingdom) in 2021 | CAS: 7748-36-9

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Name: Oxetan-3-ol

Sawano, Takahiro; Matsui, Takeshi; Koga, Marina; Ishikawa, Eri; Takeuchi, Ryo published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Iridium-catalyzed C3-selective asymmetric allylation of 7-azaindoles with secondary allylic alcohols》.Name: Oxetan-3-ol The article contains the following contents:

Iridium-catalyzed C3-selective asym. allylation of 7-azaindoles with racemic secondary allylic alcs. to give only branched allylation products in good to high yields with high enantioselectivity (up to >99.5% ee) was reported. Allylic alcs. and 7-azaindoles with a variety of functional groups including halogen and heteroaromatic groups were compatible with the reaction conditions. Furthermore, transformations of the obtained allylation products were demonstrated without a significant loss of enantiomeric excess. The results came from multiple reactions, including the reaction of Oxetan-3-ol(cas: 7748-36-9Name: Oxetan-3-ol)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Name: Oxetan-3-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Singh, Ekta’s team published research in International Journal of Pharmacy and Pharmaceutical Research in 2021 | CAS: 7748-36-9

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Formula: C3H6O2

Singh, Ekta; Matada, Gurubasavaraja Swamy Purawarga published their research in International Journal of Pharmacy and Pharmaceutical Research in 2021. The article was titled 《Chemical features responsible for the antioxidant property in 7-azaindoles and related compounds》.Formula: C3H6O2 The article contains the following contents:

The pro-oxidant mols. are reactive towards the cell organelles due to instability in their electronic composition Thus, pro-oxidants interact with and cause damages to cell organelles. This damage can be prevented by antioxidant mols. as they neutralize the pro-oxidants and render them harmless. The ability of mols. to act as an antioxidant is exhibited by its chem. feature. Alpha tocopherol and its analogs are well established antioxidants. The antioxidants can be designed based on the structure of alpha tocopherol. Some research articles have compared the antioxidant properties of alpha tocopherol and small mols. with different heterocylic rings. In continuation to the development of small antioxidant mols. azaindole analogs have also been compared with alpha tocopherol. Azaindoles are a novel class of compounds that can be developed as antioxidant mols. based on their similarity with heterocyclic rings present in reported antioxidants. In the current research we have studied some azaindole related compounds and their antioxidant properties. The objective of this study is to study some 7-azaindole related compounds as antioxidants. In this research work, small substituted azaindoles and related structures have been studied for their antioxidant properties by DPPH assay method. The structure with Ketone and double bond functional group show antioxidant property in DPPHA assay. The presence of chlorine on aromatic ring increases the antioxidant property of azaindoles. Azaindole scaffold can be used to design and develop novel antioxidant mols. After reading the article, we found that the author used Oxetan-3-ol(cas: 7748-36-9Formula: C3H6O2)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Formula: C3H6O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Samani, Kamrudeen’s team published research in International Journal of Pharmacy and Pharmaceutical Research in 2020 | CAS: 7748-36-9

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Computed Properties of C3H6O2

《In-silico approach of 7-azaindole derivatives as inhibitors of bromodomain and insulin growth factor receptors for the treatment of diabetes-related cancer》 was published in International Journal of Pharmacy and Pharmaceutical Research in 2020. These research results belong to Samani, Kamrudeen; Sharma, Uday Raj; Joshi, Abhishek Raj; V., Surendra; Pm, Manjunath; D., Giles. Computed Properties of C3H6O2 The article mentions the following:

Several 7-azaindole derivatives were designed for its dual targeted inhibition towards 1K3A and 4HY3. Drug likeness, ADME studies, virtual toxicity studies and mol. docking studies were carried out using Accelrys drug discovery studio 3.5. All the compounds were found to follow Lipinski rule of 5. Mol. docking was performed for 21 designed ligands against 1K3A and 4HY3 receptors. Some of the designed compounds possess good binding affinity towards 1K3A and 4HY3. The 21 designed 7-azaindole derivatives were then docked against 1K3A (Insulin growth factor) and 4HY3 (bromodomain) receptors. The compounds were found to be having good interaction with amino acids such as VAL 215, GLY 105, LYS 325, ASP 164, LYS 1138, LEU 1143. The compounds 3a4-(1 H-pyrrolo{2,3-b}pyridin-2-yl)benzene-1,2-diol,4a 5-(1 Hpyrrolo{2,3-b}pyridin-2-yl)benzene-1,3-diol and 20a 2-(2- iodophenyl)-1 H-pyrrolo{2,3-b}pyridine having hydroxyl- and Iodo- substitution possess dual inhibition towards bromodomain and insulin growth factor receptor. Hence, these derivatives could be effective as a dual target in drug discovery for the cancer treatment. In addition to this study using Oxetan-3-ol, there are many other studies that have used Oxetan-3-ol(cas: 7748-36-9Computed Properties of C3H6O2) was used in this study.

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Computed Properties of C3H6O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gampa, Muralimohan’s team published research in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2021 | CAS: 7748-36-9

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Category: alcohols-buliding-blocks

Gampa, Muralimohan; Padmaja, Pannala; Aravind, Seema; Reddy, Pedavenkatagari Narayana published an article in 2021. The article was titled 《An efficient one-pot synthesis of indolyl-4H-chromene derivatives》, and you may find the article in Chemistry of Heterocyclic Compounds (New York, NY, United States).Category: alcohols-buliding-blocks The information in the text is summarized as follows:

A new one-pot three-component reaction for the synthesis of indolyl-4H-chromene derivatives I (R1 = H, 6-Cl, 6-Br, 6,8-(Cl)2; R2 = 2-Me, 5-OH, 6-Br, etc.; R3 = CH, N) has been developed. The synthesis was achieved by reacting salicylaldehydes 1-CHO-2-OHC6H3R1 (R1 = H, 5-Cl, 5-Br, 3,5-Cl2), (E)-N-methyl-1-(methylsulfanyl)-2-nitroethenamine, and indoles II in the absence of solvent using triethylamine as a catalyst. The final products I were isolated by precipitation after the addition of ethanol to the reaction mixture This transformation involves the formation of indole-substituted chromene ring by creation of two C-C bonds and one C-O bond in a single synthetic operation. This rapid one-pot reaction does not require chromatog. purification and provides the indolyl-4H-chromene derivatives I in good yields. The experimental process involved the reaction of Oxetan-3-ol(cas: 7748-36-9Category: alcohols-buliding-blocks)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lavagnino, Marissa N.’s team published research in Proceedings of the National Academy of Sciences of the United States of America in 2020 | CAS: 7748-36-9

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.HPLC of Formula: 7748-36-9

《HARC as an open-shell strategy to bypass oxidative addition in Ullmann-Goldberg couplings》 was published in Proceedings of the National Academy of Sciences of the United States of America in 2020. These research results belong to Lavagnino, Marissa N.; Liang, Tao; MacMillan, David W. C.. HPLC of Formula: 7748-36-9 The article mentions the following:

Herein, an alternative aryl halide activation strategy, in which the critical oxidative addition (OA) mechanism was replaced by a halogen abstraction-radical capture (HARC) sequence that allowed the generation of the Cu(III)-aryl intermediate albeit via a photoredox pathway was presented. This alternative mechanistic paradigm decoupled the bond-breaking and bond-forming steps of the catalytic cycle to enable the use of many previously inert aryl bromides. Overall, this mechanism allowed access to both traditional C-N adducts at room temperature as well as a large range of previously inaccessible Ullmann-Goldberg coupling products including sterically demanding ortho-substituted heteroarenes, e.g., I. The experimental process involved the reaction of Oxetan-3-ol(cas: 7748-36-9HPLC of Formula: 7748-36-9)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.HPLC of Formula: 7748-36-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Giroud, Maude team published research on Journal of Medicinal Chemistry in 2018 | 7748-36-9

Reference of 7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 7748-36-9, formula is C3H6O2, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. Reference of 7748-36-9

Giroud, Maude;Kuhn, Bernd;Saint-Auret, Sarah;Kuratli, Christoph;Martin, Rainer E.;Schuler, Franz;Diederich, Francois;Kaiser, Marcel;Brun, Reto;Schirmeister, Tanja;Haap, Wolfgang research published 《 2H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design》, the research content is summarized as follows. Macrocyclic inhibitors of rhodesain (RD), a parasitic cysteine protease and drug target for the treatment of human African trypanosomiasis, have shown low metabolic stability at the macrocyclic ether bridge. A series of acyclic dipeptidyl nitriles was developed using structure-based design (PDB ID: 6EX8). The selectivity against the closely related cysteine protease human cathepsin L (hCatL) was substantially improved, up to 507-fold. In the S2 pocket, 3,4-dichlorophenylalanine residues provided high trypanocidal activities. In the S3 pocket, aromatic residues provided enhanced selectivity against hCatL. RD inhibition (Ki values) and in vitro cell-growth of Trypanosoma brucei rhodesiense (IC50 values) were measured in the nanomolar range. Triazole-based ligands, obtained by a safe, gram-scale flow production of Et 1H-1,2,3-triazole-4-carboxylate, showed excellent metabolic stability in human liver microsomes and in vivo half-lives of up to 1.53 h in mice. When orally administered to infected mice, parasitemia was reduced but without complete removal of the parasites.

Reference of 7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Goldberg, Frederick W. team published research on Journal of Medicinal Chemistry in 2014 | 7748-36-9

HPLC of Formula: 7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 7748-36-9, formula is C3H6O2, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , HPLC of Formula: 7748-36-9

Goldberg, Frederick W.;Dossetter, Alexander G.;Scott, James S.;Robb, Graeme R.;Boyd, Scott;Groombridge, Sam D.;Kemmitt, Paul D.;Sjogren, Tove;Gutierrez, Pablo Morentin;de Schoolmeester, Joanne;Swales, John G.;Turnbull, Andrew V.;Wild, Martin J. research published 《 Optimization of Brain Penetrant 11β-Hydroxysteroid Dehydrogenase Type I Inhibitors and in Vivo Testing in Diet-Induced Obese Mice》, the research content is summarized as follows. 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) has been widely considered by the pharmaceutical industry as a target to treat metabolic syndrome in type II diabetics. We hypothesized that central nervous system (CNS) penetration might be required to see efficacy. Starting from a previously reported pyrimidine compound, we removed hydrogen-bond donors to yield I, which had modest CNS penetration. More significant progress was achieved by changing the core to give II, which combines good potency and CNS penetration. Compound II was dosed to diet-induced obese (DIO) mice and gave excellent target engagement in the liver and high free exposures of drug, both peripherally and in the CNS. However, no body weight reduction or effects on glucose or insulin were observed in this model. Similar data were obtained with a structurally diverse thiazole compound III. This work casts doubt on the hypothesis that localized tissue modulation of 11β-HSD1 activity alleviates metabolic syndrome.

HPLC of Formula: 7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Felts, Andrew S. team published research on Bioorganic & Medicinal Chemistry Letters in 2019 | 7748-36-9

Name: Oxetan-3-ol, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 7748-36-9, formula is C3H6O2, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. Name: Oxetan-3-ol

Felts, Andrew S.;Bollinger, Katrina A.;Brassard, Christopher J.;Rodriguez, Alice L.;Morrison, Ryan D.;Scott Daniels, J.;Blobaum, Anna L.;Niswender, Colleen M.;Jones, Carrie K.;Jeffrey Conn, P.;Emmitte, Kyle A.;Lindsley, Craig W. research published 《 Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5》, the research content is summarized as follows. This letter describes the further chem. optimization of VU0424238 (auglurant), an mGlu5 NAM clin. candidate that failed in nonhuman primate (NHP) 28 day toxicol. due to accumulation of a species-specific aldehyde oxidase (AO) metabolite of the pyrimidine head group. Here, the authors excised the pyrimidine moiety, identified the min. pharmacophore, and then developed a new series of saturated ether head groups that ablated any AO contribution to metabolism Putative back-up compounds in this novel series provided increased sp3 character, uniform CYP450-mediated metabolism across species, good functional potency and high CNS penetration. Key to the optimization was a combination of matrix and iterative libraries that allowed rapid surveillance of multiple domains of the allosteric ligand.

Name: Oxetan-3-ol, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Friedrich, Louis E. team published research on Journal of Organic Chemistry in 1981 | 7748-36-9

7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., Synthetic Route of 7748-36-9

With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 7748-36-9, formula is C3H6O2, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Synthetic Route of 7748-36-9

Friedrich, Louis E.;Lam, Patrick Yuk-Sun research published 《 Syntheses and reactions of 3-phenyloxete and the parent unsubstituted oxete》, the research content is summarized as follows. The elimination of 4-MeC6H4SO3H and 2-O2NC6H4Se(O)OH from I (R = Ph, R1 = OSO2C6H4Me-4; R = H, R1 = OSeC6H4NO2-2) gave II (R = Ph, H), resp. II (R = Ph) underwent the expected chem. as well as a facile addition of triplet oxygen to give PhCOCH2OCHO. II (R = H) has a thermal half-life in solution at room temperature of ∼8 h.

7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., Synthetic Route of 7748-36-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Falk, Eric team published research on Angewandte Chemie, International Edition in 2020 | 7748-36-9

Recommanded Product: Oxetan-3-ol, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 7748-36-9, formula is C3H6O2, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. Recommanded Product: Oxetan-3-ol

Falk, Eric;Makai, Szabolcs;Delcaillau, Tristan;Guertler, Laura;Morandi, Bill research published 《 Design and Scalable Synthesis of N-Alkylhydroxylamine Reagents for the Direct Iron-Catalyzed Installation of Medicinally Relevant Amines》, the research content is summarized as follows. Secondary and tertiary alkylamines are privileged substance classes that are often found in pharmaceuticals and other biol. active small mols. Herein, the authors report their direct synthesis from alkenes through an aminative difunctionalization reaction enabled by iron catalysis. A family of ten novel hydroxylamine-derived aminating reagents were designed for the installation of several medicinally relevant amine groups, such as methylamine, morpholine and piperazine, through the aminochlorination of alkenes. The method has excellent functional group tolerance and a broad scope of alkenes was converted to the corresponding products, including several drug-like mols. Besides aminochlorination, the installation of other functionalities through aminoazidation, aminohydroxylation and even intramol. carboamination reactions, was demonstrated, further highlighting the broad potential of these new reagents for the discovery of novel amination reactions.

Recommanded Product: Oxetan-3-ol, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts