Category: 7748-36-9

HPLC of Formula: 7748-36-9In 2020 ,《Cu(II)-catalyzed sulfonylation of 7-azaindoles using DABSO as SO2-Source and its mechanistic study》 was published in Tetrahedron. The article was written by Urvashi; Dar, Mohammad Ovais; Bharatam, Prasad V.; Das, Parthasarathi; Kukreti, Shrikant; Tandon, Vibha. The article contains the following contents:

DABSO mediated sulfonylation of iodinated 7-azaindoles I [R = H, Cl; R1 = H, Br, 4-methoxyphenyl, 2-(4-methylphenyl)ethynyl; R2 = H, Cl, OMe, ; R3 = H, 4-methoxyphenyl] was achieved for the first time through sulfonylative Suzuki-Miyaura cross coupling (SMC) reaction under mild conditions giving good yields of sulfonylated 7-azaindole derivatives II (R4 = 3,4,5-trimethoxyphenyl, pyridin-4-yl, naphthalen-1-yl, etc.). Interestingly, control experiments suggest that present method involves in-situ generation of ArSO2 free radical followed by the key steps of SMC reaction. Scope of the reaction was explored with both electronically different and bulky group carrying boronic acids ArB(OH)2 as coupling partner. The sulfonylation is scalable and occurred selectively at iodo group, irresp. of its position on azaindole. Moreover, the proposed mechanism has been supported by ESR (EPR) and d. functional theory (DFT) calculations In the experimental materials used by the author, we found Oxetan-3-ol(cas: 7748-36-9HPLC of Formula: 7748-36-9)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.HPLC of Formula: 7748-36-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Recommanded Product: Oxetan-3-olIn 2022 ,《Visible-Light-Induced, Graphene Oxide-Promoted C3-Chalcogenylation of Indoles Strategy under Transition-Metal-Free Conditions》 was published in Molecules. The article was written by Huang, Qing; Peng, Xiangjun; Li, Hong; He, Haiping; Liu, Liangxian. The article contains the following contents:

An efficient and general method for the synthesis of 3-sulfenylindoles and 3-selenylindoles employing visible-light irradiation with graphene oxide as a promoter at room temperature has been achieved. The reaction features are high yields, simple operation, metal-free and iodine-free conditions, an easy-to-handle oxidant, and gram-scalable synthesis. This simple protocol allows one to access a wide range of 3-arylthioindoles, 3-arylselenylindoles, and even 3-thiocyanatoindoles with good to excellent yields. In the part of experimental materials, we found many familiar compounds, such as Oxetan-3-ol(cas: 7748-36-9Recommanded Product: Oxetan-3-ol)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Recommanded Product: Oxetan-3-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Degradation kinetics of target compounds and correlations with spectral indices during UV/H2O2 post-treatment of biologically treated acrylonitrile wastewater》 was published in Chemosphere in 2020. These research results belong to Tu, Xiang; Meng, Xiaoyang; Pan, Yang; Crittenden, John C.; Wang, Yaye. Reference of Oxetan-3-ol The article mentions the following:

In this study, the post-treatment of biol. treated acrylonitrile wastewater was investigated during UV/H2O2 process. Five contaminants in the effluent were selected as target compounds, including Furmaronitrile (FMN), 3-Pyridinecarbonitrile (3PCN), 1,3-Dicyanobenzene (1,3-DCB), 5-Methyl-1H-benzotriazole (5MBT), and 7-Azaindole (7AID). The UV/H2O2 post-treatment exhibited good performances in destruction of organic compounds and toxicity. The photo-chem. parameters of the target compounds were measured and it was found that 5MBT and 3PCN had fast degradation rate constants under direct UV photolysis. The second-order rate constants of the target compounds with hydroxyl radicals were determined to be in the range of (1.0-5.0) × 109 M-1 s-1 at pH 3.0 and 25°C. A simplified pseudo-first-order steady state (Sim-PSS) model, which considered direct UV photolysis and radical oxidation simultaneously, agreed well with the exptl. data. High-performance size exclusion chromatog. (HPSEC) coupled with diode-array detector (DAD) and fluorescence detector (FLD) anal. revealed that humic-like sub-peak signals from different mol. weights of fluorescent organic matter decreased consistently during the oxidation process, which made humic-like fluorescence exhibit higher correlation with the target compounds’ degradation than the spectral indexes of UV absorbance at 254 nm (UVA254) and protein-like fluorescence. In the part of experimental materials, we found many familiar compounds, such as Oxetan-3-ol(cas: 7748-36-9Reference of Oxetan-3-ol)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Reference of Oxetan-3-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Formula: C3H6O2In 2020 ,《Sulfenylation of Arenes with Ethyl Arylsulfinates in Water》 was published in ACS Omega. The article was written by Wei, Yueting; He, Jing; Liu, Yali; Xu, Liang; Vaccaro, Luigi; Liu, Ping; Gu, Yanlong. The article contains the following contents:

A tetrabutylammonium iodide-mediated direct sulfenylation of arenes with Et arylsulfinates in water was developed. Various electron-rich arenes and Et arylsulfinates were investigated in the reaction, and a series of aryl sulfides were obtained in excellent yields. The advantages of this green protocol were simple reaction conditions (metal-free, water as the solvent, and under air), odorless and easily available sulfur reagent, broad substrate scope, and gram-scale synthesis. Moreover, the potential application of aryl sulfides was exemplified by further transformations. In the experiment, the researchers used Oxetan-3-ol(cas: 7748-36-9Formula: C3H6O2)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Formula: C3H6O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Chen, Mo; Montgomery, John published an article in ACS Catalysis. The title of the article was 《Nickel-Catalyzed Intermolecular Enantioselective Heteroaromatic C-H Alkylation》.SDS of cas: 7748-36-9 The author mentioned the following in the article:

Herein, an approach involving nickel-catalyzed intermol. enantioselective C-H alkylation of heteroarenes, such as benzoxazoles, benzofurans, benzimidazoles, etc., with norbornene is presented. The process can be carried out under mild conditions using nickel(0) catalysts with N-heterocyclic carbene (NHC) ligands in the absence of Lewis acid co-catalysts. A series of NHC nickel complexes stabilized with 1,5-hexadiene was synthesized via an operationally simple approach, resulting in improved functional group tolerance and heteroarene scope. Mechanistic investigations are consistent with a ligand-to-ligand hydrogen transfer (LLHT) pathway where the C-H bond activation precedes a rate-determining reductive elimination step.Oxetan-3-ol(cas: 7748-36-9SDS of cas: 7748-36-9) was used in this study.

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.SDS of cas: 7748-36-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pan, Yue; Liu, Zhengyi; Zou, Peng; Chen, Yali; Chen, Yiyun published an article in 2022. The article was titled 《Hypervalent Iodine Reagents Enable C(sp2)-H Amidation of (Hetero)arenes with Iminophenylacetic Acids》, and you may find the article in Organic Letters.Product Details of 7748-36-9 The information in the text is summarized as follows:

The sulfonamidyl (hetero)arenes synthesis by the C(sp2)-H amidation from bench-stable amidyl-iminophenylacetic acids was reported. The hypervalent iodine reagents covalently activated iminophenylacetic acids for the facile sulfonamidyl radical generation under mild photocatalytic oxidative conditions. Diversified indoles, pyrroles, imidazopyridines and fused arenes underwent the C(sp2)-H amidation with excellent chemoselectivity and regioselectivity. This reaction performed well under neutral aqueous conditions with potential biol. applications. In the part of experimental materials, we found many familiar compounds, such as Oxetan-3-ol(cas: 7748-36-9Product Details of 7748-36-9)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Product Details of 7748-36-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Driessen, Daniel; Biesen, Lukas; Mueller, Thomas J. J. published an article in 2021. The article was titled 《Sequentially Catalyzed Three-Component Masuda-Suzuki-Sonogashira Synthesis of Fluorescent 2-Alkynyl-4-(7-azaindol-3-yl)pyrimidines: Three Palladium-Catalyzed Processes in a One-Pot Fashion》, and you may find the article in Synlett.Computed Properties of C3H6O2 The information in the text is summarized as follows:

The Masuda-Suzuki-Sonogashira sequence efficiently united in a one-pot fashion, a borylation, an arylation and an alkynylation in the sense of a sequentially Pd-catalyzed three-component reaction to give fluorescent 2-alkynyl-4-(7-azaindol-3-yl)pyrimidines in yields of 24-83%. Time-dependent d.-functional theory calculations supported the electronic structure of the longest wavelength absorption bands, and revealed that this novel consecutive three-component synthesis opened an efficient access to alkynyl meriolins, a novel class of potential inducers of apoptosis. In the part of experimental materials, we found many familiar compounds, such as Oxetan-3-ol(cas: 7748-36-9Computed Properties of C3H6O2)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Computed Properties of C3H6O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Quality Control of Oxetan-3-olIn 2022 ,《Trifluoromethyl Selenoxides: Electrophilic Reagents for C-H Trifluoromethylselenolation of (Hetero)Arene》 was published in Organic Letters. The article was written by Li, Yang; Wang, Yanan; Ye, Zhegao; Zhang, Shangbiao; Ye, Xiaodong; Yuan, Zheliang. The article contains the following contents:

Herein, designed and synthesized the new electrophilic trifluoromethylselenolation reagents, trifluoromethyl selenoxides I [X = H, CF3, CN], which were easy to prepare and easy-to-handle and were not moisture or air sensitive. The selenoxides are successfully applied to metal-free C-H trifluoromethylselenolation of a series of (hetero)arenes to gave ((trifluoromethyl)selanyl)aryl ArSeCF3 [Ar = 4-HOC6H4, 1H-indol-3-yl, (5-methoxycarbonyl-1H-pyrrol-3-yl), etc.]. After reading the article, we found that the author used Oxetan-3-ol(cas: 7748-36-9Quality Control of Oxetan-3-ol)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Quality Control of Oxetan-3-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chong, Delano P. published an article in 2021. The article was titled 《Computational study of the electron spectra of vapor-phase indole and four azaindolesã€? and you may find the article in Molecules.Application In Synthesis of Oxetan-3-ol The information in the text is summarized as follows:

After geometry optimization, the electron spectra of indole and four azaindoles are calculated by d. functional theory. Available exptl. photoemission and excitation data for indole and 7-azaindole are used to compare with the theor. values. The results for the other azaindoles are presented as predictions to help the interpretation of exptl. spectra when they become available. In the experiment, the researchers used Oxetan-3-ol(cas: 7748-36-9Application In Synthesis of Oxetan-3-ol)

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Application In Synthesis of Oxetan-3-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Quality Control of Oxetan-3-olIn 2020 ,《Reusable, homogeneous water soluble photoredox catalyzed oxidative dehydrogenation of N-heterocycles in a biphasic system: application to the synthesis of biologically active natural productsã€?appeared in Green Chemistry. The author of the article were Srinath, S.; Abinaya, R.; Prasanth, Arun; Mariappan, M.; Sridhar, R.; Baskar, B.. The article conveys some information:

A simple and efficient method for the oxidative dehydrogenation (ODH) of partially saturated N-heterocycles (indolines, tetrahydro-β-carbolines and tetrahydro(iso)quinolines) e.g., I is described using a reusable, homogeneous cobalt-phthalocyanine photoredox catalyst II (R = SO3Na; M = Co) in a biphasic medium. A biphasic system offers an advantage of easy separation of the product and an efficient reusability of the homogeneous photoredox catalyst. Also, the current system significantly helps to overcome the solubility issue of the substrate and catalyst at room temperature Its potential applications to organic transformations are demonstrated by the synthesis of various biol. active N-heterocycles (indoles, β-carbolines, (iso)quinolines) e.g., III and natural products such as eudistomin U, norharmane, and harmane and precursors to perlolyrine and flazin. Without isolation and purification, the catalyst solution can be reused up to 5 times with almost comparable reactivity. Furthermore, the efficiency of the reaction was demonstrated on a gram scale. To the best of our knowledge, this is the first report on ODH reactions using a non noble, reusable and homogeneous cobalt photoredox catalyst under environmentally friendly conditions. In addition to this study using Oxetan-3-ol, there are many other studies that have used Oxetan-3-ol(cas: 7748-36-9Quality Control of Oxetan-3-ol) was used in this study.

Oxetan-3-ol(cas: 7748-36-9) is used as a reagent in the synthesis of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists. It is also used as a reagent in the synthesis of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors.Quality Control of Oxetan-3-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts