Category: 770-71-8

Related Products of 770-71-8, Adding some certain compound to certain chemical reactions, such as: 770-71-8, name is Adamantan-1-ylmethanol,molecular formula is C11H18O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 770-71-8.

To a solution of adamantan-1-ylmethanol (1.0 g, 6.1 mmol) in DCM (20 mL), methanesulfonyl chloride (1.0 g, 9.0 mmol) and triethylamine (1.8 g, 18 mmol) were added. After stirring at room temperature over night, the reaction mixture was washed with aqueous sodium bicarbonate (10 mL) and brine (10 mL), dried over anhydrous sodium sulfate, filter and concentrated to give adamantan-1-ylmethyl methanesulfonate (1.4 g, 96%) as a white solid. 1H-NMR (500 MHz, CDCl3): delta 3.78 (s, 2H), 3.00 (s, 3H), 2.02 (s, 3H), 1.75-1.64 (m, 6H), 1.58-1.57 (m, 6H)

According to the analysis of related databases, 770-71-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; GENENTECH, INC.; XENON PHARMACEUTICALS INC.; CHEN, Chien-An; CHOWDHURY, Sultan; DEHNHARDT, Christoph Martin; SUN, Shaoyi; WO2014/144545; (2014); A2;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Electric Literature of 770-71-8 , The common heterocyclic compound, 770-71-8, name is Adamantan-1-ylmethanol, molecular formula is C11H18O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

The adamantane 4-methylbenzenesulfonate was synthesized by reacting adamantyl alcohol (20.5 g, 123 mmol) with p-toluenesulfonic chloride (23.6 g, 123 mmol) in 75 mL of regular DCM, in the presence of 25 mL of triethylamine for 48 hours at room temperature. More DCM was added (100 mL) and the organic layer was washed with water (3×100 mL). Drying, (MgSO4), and evaporation of the solvent gave 34.5 g of tea color oil which under trituration with hexane afforded white solid adamantane 4-methylbenzenesulfonate (30.5 g, 76%).

The synthetic route of 770-71-8 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; NITTO DENKO CORPORATION; RACHWAL, MILA; YAMAMOTO, MICHIHARU; (134 pag.)JP2016/509621; (2016); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Related Products of 770-71-8, Adding some certain compound to certain chemical reactions, such as: 770-71-8, name is Adamantan-1-ylmethanol,molecular formula is C11H18O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 770-71-8.

To a solution of 500 mg (1.89 mmol) of N-Boc-L-phenylalanine in 25 ml of dichloromethane were added, at RT, 1192 mg (6.2 mmol) of EDC, 578 mul (4.1 mmol) of triethylamine, 345 mg (2.8 mmol) of DMAP and 345 mg (2.1 mmol) of 1-adamantylmethanol. The reaction mixture was stirred overnight, then diluted with 50 ml of dichloromethane, and was successively washed with 10% aqueous citric acid solution, water and saturated sodium chloride solution. The organic phase was dried over magnesium sulphate, then concentrated, and the residue was purified by preparative HPLC. 769 mg (90% of theory) of the title compound were obtained. [1516] LC-MS (Method 2): Rt=1.84 min; m/z=414 (M+H)+

According to the analysis of related databases, 770-71-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Lerchen, Hans-Georg; Hammer, Stefanie; Harrenga, Axel; Kopitz, Charlotte Christine; Nising, Carl Friedrich; Sommer, Anette; Stelte-Luowig, Beatrix; Mahlert, Christoph; Schuhmacher, Joachim; Golfier, Sven; Greven, Simone; Bruder, Sandra; US2015/23989; (2015); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 770-71-8, Name is Adamantan-1-ylmethanol, SMILES is OCC12CC3CC(C2)CC(C3)C1, in an article , author is Simonato, Barbara, once mentioned of 770-71-8, Application In Synthesis of Adamantan-1-ylmethanol.

Effects of post-harvest fungal infection of apples on chemical characteristics of cider

The impact of fungal post-harvest infection of apple on the chemical composition of cider was investigated through a comparative analysis of ciders obtained from apples (Gala variety) separately infected by five fungal species (Alternaria alternata, Botrytis cinerea, Diplodia seriata, Monilinia fructigena, and Penicillium expansum) and cider from sound apples. The content of several flavor-active molecules belonging to different chemical groups, such as alcohols, esters, acids, aldehydes, phenols, and lactones, significantly varied among ciders. Particularly, cider from sound apples had a higher concentration of ethyl ester acetate, fatty acid ethyl esters and fatty acids, molecules that contribute to fruity and sweet scent. Principal component analysis well discriminated ciders, evidencing species-specific fungal effect. Differences in precursor availability in juices and biosynthesis pathways in fungi could explain changes in aroma profile of ciders. This study provides information on the potential risk to produce cider from infected apples due to the possible quality depreciation.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 770-71-8, you can contact me at any time and look forward to more communication. Application In Synthesis of Adamantan-1-ylmethanol.

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 770-71-8, Name is Adamantan-1-ylmethanol, SMILES is OCC12CC3CC(C2)CC(C3)C1, in an article , author is Ray, Ritwika, once mentioned of 770-71-8, Quality Control of Adamantan-1-ylmethanol.

Oxalohydrazide Ligands for Copper-Catalyzed C-O Coupling Reactions with High Turnover Numbers

Here, we report a class of ligands based on oxalohydrazide cores and N-amino pyrrole and N-amino indole units that generates long-lived copper catalysts for couplings that form the C-O bonds in biaryl ethers. These Cu-catalyzed coupling of phenols with aryl bromides occurred with turnovers up to 8000, a value which is nearly two orders of magnitude higher than those of prior couplings to form biaryl ethers and nearly an order of magnitude higher than those of any prior copper-catalyzed coupling of aryl bromides and chlorides. This ligand also led to copper systems that catalyze the coupling of aryl chlorides with phenols and the coupling of aryl bromides and iodides with primary benzylic and aliphatic alcohols. A wide variety of functional groups including nitriles, halides, ethers, ketones, amines, esters, amides, vinylarenes, alcohols and boronic acid esters were tolerated, and reactions occurred with aryl bromides in pharmaceutically related structures.

Interested yet? Read on for other articles about 770-71-8, you can contact me at any time and look forward to more communication. Quality Control of Adamantan-1-ylmethanol.

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts

Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Hill, Melanie L., once mentioned the application of 770-71-8, Name is Adamantan-1-ylmethanol, molecular formula is C11H18O, molecular weight is 166.26, MDL number is MFCD00074751, category is alcohols-buliding-blocks. Now introduce a scientific discovery about this category, HPLC of Formula: C11H18O.

Comparative associations of problematic alcohol and cannabis use with suicidal behavior in US military veterans: A population-based study

Alcohol use disorder (AUD) and cannabis use disorder (CUD) are each associated with increased suicidal behavior, but it is unclear how their comorbidity relates to suicide risk. Understanding these associations in U.S. military veterans is especially important, given their heightened risk for suicide, high prevalence of AUD, and increasing access to cannabis. We compared associations of probable AUD, CUD, and AUD/CUD with suicide ideation, plan(s), and attempt(s) in a nationally representative sample of 4,069 veterans surveyed in 2019-2020 as part of the National Health and Resilience in Veterans Study. Among veterans who screened positive for current AUD, 8.7% also screened positive for current CUD. Among veterans who screened positive for current CUD, 33.3% screened positive for current AUD. Current and lifetime positive screens for AUD, CUD, and AUD/ CUD were each strongly and independently associated with past-year suicide ideation and lifetime suicide ideation, plan(s), and attempt(s) [odds ratios (ORs) = 1.6-8.7]. Relative to veterans who screened positive for AUD only, veterans who screened positive for AUD/CUD and CUD only had higher odds of past-year suicide ideation (AUD/CUD: OR = 3.3; CUD only: OR = 2.4), lifetime suicide ideation (AUD/CUD: OR = 1.9; CUD only: OR = 2.6) and lifetime suicide plan(s) (AUD/CUD: OR = 1.7; CUD only: OR = 6.1). Collectively, findings suggest that screening positive for CUD might be an especially strong indicator of suicide ideation and planning in veterans with and without AUD, independent of sociodemographic, military, trauma, and other psychiatric factors. These findings underscore the importance of routine screening for CUD in suicide prevention efforts, especially as cannabis becomes more widely available.

Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 770-71-8, HPLC of Formula: C11H18O.

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 770-71-8, Name is Adamantan-1-ylmethanol, molecular formula is C11H18O. In an article, author is Fang, Jun,once mentioned of 770-71-8, Formula: C11H18O.

Thermochemical liquefaction of cattle manure using ethanol as solvent: Effects of temperature on bio-oil yields and chemical compositions

Cattle manure was converted into bio-oil via suband super-critical liquefaction with ethanol as the solvent. The effects of various reaction parameters, including the reaction temperature (T, 180-300 degrees C), solid-liquid ratio (S-1, 5-15%), and solvent filling ratios (S-2, 10-30%) on the yield of bio-oil (OCM) and residue (RCM) from liquefaction of cattle manure were studied. The yield of bio-oil was positively correlated to reaction temperature suggesting higher reaction temperature could promote the fragmentation of the polymers transformed into a liquid oil-rich phase and the maximum OCM relative yield (32.14 +/- 0.19%) was obtained at 300 degrees C. OCM had HHV of 25.63-33.41 MJ/kg and LHV of 23.85-31.39 MJ/ kg, respectively, suggesting their potential for use as a renewable energy to replace fossil energy. The GC-MS analyses demonstrated that the major compounds in OCM were esters, hydrocarbons, alcohols, phenolic compounds, nitrogenous and bromine components, the compositions of OCM was similar to that of biodiesel. The presence of ester compounds in OCM which was attributed to the degradation of cellulose and hemicelluloses. Carbon-normal paraffin gram (C-NP) analysis indicated that C-18 and C-20 species comprised the bulk of the hydrocarbon compounds from OCM. (c) 2020 Elsevier Ltd. All rights reserved.

Interested yet? Keep reading other articles of 770-71-8, you can contact me at any time and look forward to more communication. Formula: C11H18O.

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts

Synthetic Route of 770-71-8, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 770-71-8, Name is Adamantan-1-ylmethanol, SMILES is OCC12CC3CC(C2)CC(C3)C1, belongs to alcohols-buliding-blocks compound. In a article, author is Salih, Kifah S. M., introduce new discover of the category.

New tetradentate Schiff base Cu(II) complexes: synthesis, physicochemical, chromotropism, fluorescence, thermal, and selective catalytic oxidation

Three neutral Cu(II)/n(4)-NNNO Schiff base complexes (1-3) were prepared from the (E)-4-nitro-2-(((2-(piperazin-1-yl)ethyl)imino)methyl)phenol, tetradentate Schiff base (SB) ligand, and the corresponding copper(II) salts. The new SB and its complexes were fully characterized by CHN-EA, standard spectroscopic, thermal, and fluorescence analyses. The formation of the complexes was monitored by EDX, FT-IR, and UV-Vis. The chromotropism studies of the complexes reflected remarkable findings, in which bathochromic solvato- and thermochromism shifts were detected. The turn-off-on halochromism phenomena were observed in the acidic and basic medium. On the other hand, the fluorescence of the free SB ligand was turned off via complexation to the Cu(II) center. In the presence of H2O2 as green oxidant and under mild oxidation catalytic condition, the three complexes successfully catalyzed the formation benzaldehyde from benzyl alcohol.

Synthetic Route of 770-71-8, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 770-71-8 is helpful to your research.

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 770-71-8, Name is Adamantan-1-ylmethanol, molecular formula is C11H18O. In an article, author is Sharma, Teenu,once mentioned of 770-71-8, Recommanded Product: 770-71-8.

An HPTLC densitometric method for simultaneous quantification of sorafenib tosylate and chrysin: Analytical method development, validation and applications

Since decades, the plant bioactives have shown tremendous promise in the therapeutic management of cancer. Lately, many synthetic drugs and natural bioactive molecules have been used in combination for potential synergism in cancer therapeutics. Sorafenib (SFN) and chrysin (CHR) form one of such promising combinations with definitive synergistic potential in cancer therapy. This has, however, given rise to analytical challenges, as it becomes quite difficult to identify and quantify two or more active moieties simultaneously in the presence of each other. Herein, we report the development and validation of an HPTLC densitometric method for analysis of SFN and CHR, in combination, followed by studying the effect of biological matrix (i.e., plasma), on the assay of both the molecules. Solvent system, comprising of toluene: n-hexane: isopropyl alcohol (7:2:1), was employed for chromatographic separation with Rf values of 0.3 and 0.5, for SFN and CHR, respectively. Validation studies established linearity for the concentrations ranging from 20 to 800 ng/band for each of the molecules, along with high degree of accuracy, precision (intraand inter-day), ruggedness, robustness, and sensitivity of the liquid chromatographic method. Specificity studies using plasma as the biological matrix, exhibited well-resolved peaks of both the molecules, coupled with high recovery values too. The aforesaid method was finally applied to the estimation of real plasma levels in Wistar rats, following co-administration of SFN and CHR as a suspension. In a nutshell, the validated analytical method can be productively applied for simultaneous estimation of SFN and CHR, for routine analysis, in drug formulations and in biological matrices like plasma.

Interested yet? Keep reading other articles of 770-71-8, you can contact me at any time and look forward to more communication. Recommanded Product: 770-71-8.

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts

Chemistry, like all the natural sciences, Product Details of 770-71-8, begins with the direct observation of nature— in this case, of matter.770-71-8, Name is Adamantan-1-ylmethanol, SMILES is OCC12CC3CC(C2)CC(C3)C1, belongs to alcohols-buliding-blocks compound. In a document, author is Kalomo, Eveline Ndinelao, introduce the new discover.

Depressive symptoms among older adults with HIV in Namibia: The role of social support and spirituality

Background: More than 60% of older adults living with HIV reside in sub-Saharan Africa. Namibia has one of the highest HIV/AIDS prevalence rates. This study examined the association between social support, spirituality and depressive symptoms. Method and results: The sample consisted of 147 Oshiwambo-speaking older adults (mean age = 61 years, SD = 6.92 years) with HIV in Namibia. By utilising a hierarchical multivariate regression method, this study found that social support from friends and spirituality showed a significant negative relationship to depressive symptoms. In addition, self-rated health status and alcohol use were significant sociodemographic predicitive factors of depressive symptoms. Conclusion: This study suggests the need to develop interventions and support programmes that incorporate peer support and spiritual practice to promote health and well-being among older persons living with HIV in Namibia.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 770-71-8. Product Details of 770-71-8.

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts