Category: 767-90-8

Reference of 767-90-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 767-90-8, name is (2-Ethylphenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows.

To a solution of (2-ethylphenyl)metha- nol (13-1, 1.00 g, 7.3 mmol) in DMF (25 mE) at room temperature under nitrogen, N135 (2.6 g, 14.6 mmol) and triphenylphosphine (4.03 g, 15.3 mmol) were added sequentially. The mixture was heated to 50 C. overnight, cooled to room temperature and diluted with water and dichloromethane. The aqueous layer was extracted twice more with dichioromethane and the organic layers were combined, washed with brine, dried, filtered and concentrated. The residue was purified by silica gel column chromatography, eluting with 10% ethyl acetate in hexanes to give 1-(bromomethyl)-2-ethylbenzene (13-2, 1.1 g) as an oil.

According to the analysis of related databases, 767-90-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Aviara Pharmaceuticals, Inc.; Biediger, Ronald J.; Benish, Michele A.; Market, Robert V.; Savage, Michael M.; Young, Brandon M.; (49 pag.)US2018/312498; (2018); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Adding a certain compound to certain chemical reactions, such as: 767-90-8, (2-Ethylphenyl)methanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 767-90-8, blongs to alcohols-buliding-blocks compound. Recommanded Product: 767-90-8

Step 1: A solution of (2-ethylphenyl)methanol (500 mg, 3.67 mmol) and triethylamine (742 mg, 7.34 mmol) in DCM (5 mL) was added MsCI (1.0 g, 8.73 mmol) at 000 and stirred at 000 for 0.5 hour. Then it was stirred at 20C for 1 hour. The mixture was quenched with water (0.5 mL), and diluted with DCM (10 mL). The mixture was added NaHCO3 (aq.) until pH=8. The organic layer was washed with water (3 x 5 mL), dried with an hydrous Na2504, filteredand concentrated under vacuum to give 2-ethylbenzyl methanesulfonate (600 mg), which was used into the next step without further purification.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,767-90-8, its application will become more common.

Reference:
Patent; H. LUNDBECK A/S; KEHLER, Jan; RASMUSSEN, Lars, Kyhn; LANGGARD, Morten; JESSING, Mikkel; VITAL, Paulo, Jorge, Vieira; JUHL, Karsten; (159 pag.)WO2016/174188; (2016); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Related Products of 767-90-8, Adding some certain compound to certain chemical reactions, such as: 767-90-8, name is (2-Ethylphenyl)methanol,molecular formula is C9H12O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 767-90-8.

To a cooled (0C) solution of compound 29 (55.0 g, 404 mmol) in CH2C12 (400 mL) was added Dess-Martin periodinane (177 g, 417 mmol) portionwise. After stirring for lh at r.t., the reaction mixture was quenched with saturated aqueous Na2S2O3 (300 mL) and saturatedaqueous NaHCO3 (500 mL). The mixture was extracted with CH2C12 (3x 300 mL). The combined organic extracts were washed with water and brine, dried over Na2SO4 and concentrated to yield 51.0 g of crude compound 30 as a yellow solid.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 767-90-8, (2-Ethylphenyl)methanol, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; AICURIS GMBH & CO. KG; DONALD, Alastair; URBAN, Andreas; BONSMANN, Susanne; WEGERT, Anita; GREMMEN, Christiaan; SPRINGER, Jasper; (376 pag.)WO2019/86141; (2019); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts