Category: 76-84-6

Shi, Quan-Xi; Li, Qian; Xiao, Hang; Sun, Xiao-Li; Bao, Hongli; Wan, Wen-Ming published the artcile< Room-temperature Barbier single-atom polymerization induced emission as versatile approach for utilization of monofunctional carboxylic acid resources>, Computed Properties of 76-84-6, the main research area is phenylcarboxylic acid dibenzoyl peroxide polytriphenylmethanol Barbier single atom polymerization.

Carboxylic acids are widely available from both biomass and fossil sources on the Earth. In comparison with multifunctional carboxylic acid containing chems. that have been comprehensively used as building blocks of polymer materials, monofunctional carboxylic acid resources exhibit broader availability but are rarely utilized as monomers for polymerization, attributed to their monofunctionality. Here, we demonstrate a Barbier single-atom polymerization (SAP) as a versatile approach for the utilization of monofunctional carboxylic acid resources, where they act as a carbon source to contribute only one carbon atom for the construction of the polymer main chain. The key point for the polymerization of the monofunctional carboxylic acid resource is to difunctionalize it, which is realized through two Barbier additions between bifunctional aromatic halides and monofunctional peroxyester in the presence of Mg. Prior to the Barbier SAP, monofunctional phenylcarboxylic acid is converted into dibenzoyl peroxide (BPO) with higher reactivity. Through the Barbier SAP of BPO at room temperature, a series of nonconjugated polytriphenylmethanols (PTPMs) were prepared as polymerization-induced emission luminogens (PIEgens) with structure-specific nonconjugated luminescence including aggregation-caused quenching (ACQ) and aggregation induced emission (AIE) characteristics, where starting monomers and repeating units are nonemissive. Further applications of PIEgens were carried out for an artificial light-harvesting system with an antenna effect of over 18.5 and explosive detection at the ppm level in solution and ng level on test paper. This work therefore opens a new avenue for the design of nonconjugated luminescence by utilizing Earth’s monofunctional carboxylic acid resources sufficiently.

Polymer Chemistry published new progress about Aggregation-induced emission. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Computed Properties of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Quivelli, Andrea F.; D’Addato, Giovanna; Vitale, Paola; Garcia-Alvarez, Joaquin; Perna, Filippo M.; Capriati, Vito published the artcile< Expeditious and practical synthesis of tertiary alcohols from esters enabled by highly polarized organometallic compounds under aerobic conditions in Deep Eutectic Solvents or bulk water>, Computed Properties of 76-84-6, the main research area is tertiary alc preparation; organometallic compound ester nucleophilic addition.

An efficient protocol was developed for the synthesis of tertiary alcs. R1C(OH)(R2)R2 [R1 = Ph, 4-MeC6H4, 4-MeOC6H4, etc.; R2 = Me, i-Pr, Ph, etc.] via nucleophilic addition of organometallic compounds of s-block elements (Grignard and organolithium reagents) to esters performed in the biodegradable choline chloride/urea eutectic mixture or in water. This approach displayed a broad substrate scope, with the addition reaction proceeded quickly (20 s reaction time) and cleanly, at ambient temperature and under air, straightforwardly furnished the expected tertiary alcs. in yields of up to 98%. The practicability of the method was exemplified by the sustainable synthesis of some representative S-trityl-L-cysteine derivatives, which were a potent class of Eg5 inhibitors, also via telescoped one-pot processes.

Tetrahedron published new progress about Deep eutectic solvents. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Computed Properties of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Yu; Xu, Tie-Qi published the artcile< Topology-Controlled Ring-Opening Polymerization of O-Carboxyanhydride>, Recommanded Product: Triphenylmethanol, the main research area is topol controlled ring opening polymerization phenylmandelate carboxyanhydride; stereocomplex linear cyclic polyphenylmandelate enantiomer.

The ring-opening polymerization (ROP) of O-carboxyanhydride (OCA) is the most powerful approach to produce diverse poly(α-hydroxyalkanoic acid) (PAHA) with functional groups as an easy modification of the side group of OCA. Previous studies focus on the ROP of OCA to produce linear PAHA, whereas no example was reported regarding the cyclic PAHA. Here, a synthesis strategy is reported for controlling the topol. of stereoregular PAHA by the ROP of OCA. La[N(SiMe3)2]3 catalyst yields highly isotactic cyclic polymer, while Zn[N(SiMe3)2]2/BnOH catalyst system favors highly isotactic linear ones. The individual enantiomerically pure cyclic or linear PAHA generates homocrystallites, which displayed distinct melting temperature (Tm) up to 190°C. Mixing of these opposite enantiomerically pure cyclic or linear polymers in equivalent amounts affords the crystalline stereocomplexed PAHAs. This study provides a new approach to create crystalline polymers with controlled geometry, allowing a better understanding of the relationship between structure and properties to expand the potentials of their materials.

Macromolecules (Washington, DC, United States) published new progress about Crystallites. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Recommanded Product: Triphenylmethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Yu; Qin, Shaowei; Claes, Nathalie; Schilling, Waldemar; Sahoo, Prakash Kumar; Ching, H. Y. Vincent; Jaworski, Aleksander; Lemiere, Filip; Slabon, Adam; Van Doorslaer, Sabine; Bals, Sara; Das, Shoubhik published the artcile< Direct Solar Energy-Mediated Synthesis of Tertiary Benzylic Alcohols Using a Metal-Free Heterogeneous Photocatalyst>, Reference of 76-84-6, the main research area is tertiary benzylic alc preparation; carbon hydrogen bond hydroxylation photocatalyst solar energy.

Direct hydroxylation via the functionalization of tertiary benzylic C(sp3)-H bonds is of great significance for obtaining tertiary alcs., which find wide applications in pharmaceuticals as well as in fine chem. industries. However, current synthetic procedures use toxic reagents, and therefore, the development of a sustainable strategy for the synthesis of tertiary benzylic alcs. is highly desirable. To solve this problem, herein, a metal-free heterogeneous photocatalyst to synthesize the hydroxylated products using oxygen as the key reagent is reported. Various benzylic substrates were employed into the mild reaction conditions to afford the desirable products in good to excellent yields. More importantly, the gram-scale reaction was achieved via harvesting direct solar energy and exhibited high quantity of the product. The high stability of the catalyst was proved via recycling the catalyst and spectroscopic analyses. Finally, a possible mechanism was proposed based on the ESR and other exptl. evidence.

ACS Sustainable Chemistry & Engineering published new progress about Aromatic compounds Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Reference of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Diamandas, Matthew; Moreira, Ryan; Taylor, Scott D. published the artcile< Solid-phase total synthesis of dehydrotryptophan-bearing cyclic peptides tunicyclin B, sclerotide A, CDA3a, and CDA4a using a protected β-hydroxytryptophan building block>, Safety of Triphenylmethanol, the main research area is cyclic peptide dehydrotryptophan solid phase total synthesis antibacterial agent; tunicyclin B sclerotide A CDA3a CDA4a hydroxytryptophan protected.

A new approach to the synthesis of Z-dehydrotryptophan (ΔTrp) peptides is described. This approach uses Fmoc-β-HOTrp(Boc)(TBS)-OH as a building block, which is readily prepared in high yield and incorporated into peptides using solid-phase Fmoc chem. The tert-butyldimethylsilyl-protected indolic alc. is eliminated during global deprotection/resin cleavage to give ΔTrp peptides exclusively as the thermodynamically favored Z isomer. This approach was applied to the solid-phase synthesis of tunicyclin B, sclerotide A, CDA3a, and CDA4a.

Organic Letters published new progress about Antibacterial agents. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Safety of Triphenylmethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Arnold, Polly L.; Purkis, Jamie M.; Rutkauskaite, Ryte; Kovacs, Daniel; Love, Jason B.; Austin, Jonathan published the artcile< Controlled photocatalytic hydrocarbon oxidation by uranyl complexes>, Product Details of C19H16O, the main research area is uranyl phenanthroline hydrocarbon oxidation photocatalyst.

Controlled, photocatalytic C-H bond activations are key reactions in the toolkits of the modern synthetic chemist. While it is known that the uranyl(VI) ion, [UVIO2]2+, the environmentally dominant form of uranium, is photoactive, most literature examines its luminescent properties, neglecting its potential synthetic utility for photocatalytic C-H bond cleavage. Here, we synthesize and fully characterize an air-stable and hydrocarbon-soluble uranyl phenanthroline complex, [UVIO2(NO3)2(Ph2phen)], UPh2phen, and demonstrate that it can catalytically abstract hydrogen atoms from a variety of organic substrates under visible light irradiation We show that the com. available parent complex, uranyl nitrate ([UVIO2(NO3)2(OH2)2][n.8901]4H2O; UNO3), is also competent, but from electronic spectroscopy we attribute the higher rates and selectivity of UPh2phen to ligand-mediated electronic effects. Ketones are selectively formed over other oxygenated products (alcs., etc.), and the catalytic oxidation of substrates containing a benzylic C-H position is particularly improved for UPh2phen. We also show uranyl-mediated photocatalytic C-C bond cleavage in a model lignin compound for the first time.

ChemCatChem published new progress about Amines, rare earth complexes Role: CAT (Catalyst Use), PRP (Properties), SPN (Synthetic Preparation), USES (Uses), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Product Details of C19H16O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Vezse, Panna; Benda, Bianka; Fekete, Andras; Golcs, Adam; Toth, Tunde; Huszthy, Peter published the artcile< Covalently Immobilizable Tris(Pyridino)-Crown Ether for Separation of Amines Based on Their Degree of Substitution>, Name: Triphenylmethanol, the main research area is amine separation trispyridinocrown ether mol recognition; biogenic amine; crown ether; molecular recognition; separation.

A great number of biol. active compounds contain at least one amine function. Appropriate selectivity can only be accomplished in a few cases upon the substitution of these groups, thus functionalization of amines generally results in a mixture of them. The separation of these derivatives with very similar characteristics can only be performed on a preparative scale or by applying pre-optimized HPLC methods. A tris(pyridino)-crown ether was designed and synthesized for overcoming these limitations at a mol. level. It is demonstrated, that this selector mol. is able to distinguish protonated primary, secondary and tertiary amines by the formation of reversible complexes with different stabilities. This degree of substitution-specific mol. recognition of amines opens the door to develop separation processes primarily focusing on the purification of biol. active compounds in a nanomolar scale.

Molecules published new progress about Crown ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Name: Triphenylmethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lutz, Marius D. R.; Gasser, Valentina C. M.; Morandi, Bill published the artcile< Shuttle arylation by Rh(I) catalyzed reversible carbon-carbon bond activation of unstrained alcohols>, Electric Literature of 76-84-6, the main research area is tertiary alc green preparation crystal structure mol; triaryl alc ketone bond activation rhodium catalyst.

Herein, a rhodium(I)-catalyzed shuttle arylation cleaving the C(sp2)-C(sp3) bond in unstrained triaryl alcs. via a redox-neutral β-carbon elimination mechanism was reported. A selective transfer hydrocarbylation of substituted (hetero)aryl groups from tertiary alcs. to ketones was realized, employing benign alcs. as latent C-nucleophiles. All preliminary mechanistic experiments support a reversible β-carbon elimination/migratory insertion mechanism. In a broader context, this novel reactivity offers a new platform for the manipulation of tertiary alcs. in catalysis.

Chem published new progress about Bond activation. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Electric Literature of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Vezse, Panna; Benda, Bianka; Fekete, Andras; Golcs, Adam; Toth, Tunde; Huszthy, Peter published the artcile< Covalently Immobilizable Tris(Pyridino)-Crown Ether for Separation of Amines Based on Their Degree of Substitution>, Name: Triphenylmethanol, the main research area is amine separation trispyridinocrown ether mol recognition; biogenic amine; crown ether; molecular recognition; separation.

A great number of biol. active compounds contain at least one amine function. Appropriate selectivity can only be accomplished in a few cases upon the substitution of these groups, thus functionalization of amines generally results in a mixture of them. The separation of these derivatives with very similar characteristics can only be performed on a preparative scale or by applying pre-optimized HPLC methods. A tris(pyridino)-crown ether was designed and synthesized for overcoming these limitations at a mol. level. It is demonstrated, that this selector mol. is able to distinguish protonated primary, secondary and tertiary amines by the formation of reversible complexes with different stabilities. This degree of substitution-specific mol. recognition of amines opens the door to develop separation processes primarily focusing on the purification of biol. active compounds in a nanomolar scale.

Molecules published new progress about Crown ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Name: Triphenylmethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lutz, Marius D. R.; Gasser, Valentina C. M.; Morandi, Bill published the artcile< Shuttle arylation by Rh(I) catalyzed reversible carbon-carbon bond activation of unstrained alcohols>, Electric Literature of 76-84-6, the main research area is tertiary alc green preparation crystal structure mol; triaryl alc ketone bond activation rhodium catalyst.

Herein, a rhodium(I)-catalyzed shuttle arylation cleaving the C(sp2)-C(sp3) bond in unstrained triaryl alcs. via a redox-neutral β-carbon elimination mechanism was reported. A selective transfer hydrocarbylation of substituted (hetero)aryl groups from tertiary alcs. to ketones was realized, employing benign alcs. as latent C-nucleophiles. All preliminary mechanistic experiments support a reversible β-carbon elimination/migratory insertion mechanism. In a broader context, this novel reactivity offers a new platform for the manipulation of tertiary alcs. in catalysis.

Chem published new progress about Bond activation. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Electric Literature of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts