Category: 70445-33-9

Wakita, Masahiro published the artcileSun protection by new vitamin C derivatives, Category: alcohols-buliding-blocks, the publication is Fragrance Journal (2021), 49(8), 36-41, database is CAplus.

Photoaging is caused by not only UV, but also blue light and near-IR rays. Reactive oxygen species (ROS) is generated inside our skin when the skin is exposed to these lights. As a result, wrinkles and sagging appear on the skin cause due to collagen and elastin reduced. Avoiding light exposure is the best solution against photoaging, but scavenging ROS is also important as the solution Generally, vitamin C is known as a cosmetic ingredient with strong antioxidant effect that eliminates ROS. However, it has problems of stability in itself and formulation. Therefore, author develops a highly stable vitamin C derivative 3-glyceryl ascorbate (3GA). It has a high stability in itself and formulation, in addition, author confirms its anti-photoaging effect improves wrinkles.

Fragrance Journal published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C12H16O3, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dinkloh, A. published the artcileContact sensitization in patients with suspected cosmetic intolerance: results of the IVDK 2006-2011, Quality Control of 70445-33-9, the publication is Journal of the European Academy of Dermatology and Venereology (2015), 29(6), 1071-1081, database is CAplus and MEDLINE.

Background : Ingredients of leave-on cosmetics and body care products may sensitize. However, not every case of cosmetic intolerance is due to contact sensitization. Objective : To describe the frequency of contact sensitization due to cosmetics in a large clinic population, and a possible particular allergen pattern. Methods : Retrospective anal. of data from the Information Network of Departments of Dermatol., 2006-2011. Results : Of 69 487 patients tested, ‘cosmetics, creams, sunscreens’ was the only suspected allergen source category in 10 124 patients (14.6%). A final diagnosis ‘allergic contact dermatitis’ was stated in 2658 of these patients (26.3%).Compared to a control group, there were significantly more reactions to fragrance mixes I and II, balsam of Peru, methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) and lanolin alcs. No special pattern of fragrance sensitization could be identified. Among the preservatives, MI was by far the leading allergen, while sensitization to other widely used compounds like parabens or phenoxyethanol was rare. Conclusions : True allergic reactions to cosmetic ingredients are rarer than generally assumed. Limitation of exposure to MI in leave-on cosmetics and body care products is urgently needed.

Journal of the European Academy of Dermatology and Venereology published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Quality Control of 70445-33-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Radzki, Dominik published the artcileA Fresh Look at Mouthwashes-What Is Inside and What Is It For?, Quality Control of 70445-33-9, the publication is International Journal of Environmental Research and Public Health (2022), 19(7), 3926, database is CAplus and MEDLINE.

Mouthwashes are a very popular addnl. oral hygiene element and there are plenty of individual products, whose compositions are in a state of flux. The aim of our study was to investigate the compositions of mouthwashes and their functions, as well as to discuss their effectiveness in preventing and curing oral diseases and side effects. We searched for mouthwashes available on the market in Poland. We identified 241 individual mouthwash products. The extraction of compositions was performed and functions of the ingredients were assessed. Then, anal. was performed. The evaluation revealed that there are plenty of ingredients, but a typical mouthwash is a water-glycerin mixture and consists of addnl. sweetener, surfactant, preservative, and some colorant and flavoring agent, as well as usually having two oral health substances, anticaries sodium fluoride and antimicrobial essential oils. The effectiveness or side effects of several substances of mouthwashes were thoroughly discussed. We recommend not multiplying individual mouthwash products and their ingredients beyond medical or pharmaceutical necessity, especially without scientific proof.

International Journal of Environmental Research and Public Health published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Quality Control of 70445-33-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Nakamura, Shohei published the artcileDevelopment and application of functional powder coated by perfluoropolyoxypropylene (PFPOP) derivative, Application of 3-((2-Ethylhexyl)oxy)propane-1,2-diol, the publication is Fragrance Journal (2017), 45(3), 38-41, database is CAplus.

For cosmetic ingredients, the surface treated clay powders are well used. Especially perfluoroalkyl derivatives are widely used for their water or sebum proof properties. We developed a novel perfluoropolyoxypropylene derivative and used as a surface treatment agent. Surface treated clay powders had much higher water and oil repellency and better smoothness. We confirmed its long lasting effect by applying it to powder foundation formulation with 30wt% surface treated powder.

Fragrance Journal published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Application of 3-((2-Ethylhexyl)oxy)propane-1,2-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Abendrot, Michal published the artcileZinc(II) complexes of amino acids as new active ingredients for anti-acne dermatological preparations, Formula: C11H24O3, the publication is International Journal of Molecular Sciences (2021), 22(4), 1641, database is CAplus and MEDLINE.

Zinc compounds have a number of beneficial properties for the skin, including antimicrobial, sebostatic and demulcent activities. The aim of the study was to develop new anti-acne preparations containing zinc-amino acid complexes as active ingredients. Firstly, the cytotoxicity of the zinc complexes was evaluated against human skin fibroblasts (1BR.3.N cell line) and human epidermal keratinocyte cell lines, and their antimicrobial activity was determined against Cutibacterium acnes. Then, zinc complexes of glycine and histidine were selected to create original gel formulations. The stability (by measuring pH, d. and viscosity), microbiol. purity (referring to PN-EN ISO standards) and efficacy of the preservative system (according to Ph.Eur. 10 methodol.) for the preparations were evaluated. Skin tolerance was determined in a group of 25 healthy volunteers by the patch test. The preparations containing zinc(II) complexes with glycine and histidine as active substances can be topically used in the treatment of acne skin due to their high antibacterial activity against C. acnes and low cytotoxicity for the skin cells. Dermatol. recipes have been appropriately composed; no irritation or allergy was observed, and the preparations showed high microbiol. purity and physicochem. stability.

International Journal of Molecular Sciences published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Formula: C11H24O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Leal-Duaso, Alejandro published the artcileGlycerol as a source of designer solvents: physicochemical properties of low melting mixtures containing glycerol ethers and ammonium salts, Synthetic Route of 70445-33-9, the publication is Physical Chemistry Chemical Physics (2017), 19(41), 28302-28312, database is CAplus and MEDLINE.

In this work we report the preparation of mixtures of several alkyl glyceryl ethers, as hydrogen bond donor compounds, with two ammonium salts, choline chloride and N,N,N-triethyl-2,3-dihydroxypropan-1-aminium chloride. The stability of the mixtures at different molar ratios and temperatures has been evaluated in order to determine the formation of low melting mixtures Liquid and stable mixtures have been characterized and their physico-chem. properties such as d., viscosity, refractive index, conductivity and surface tension have been measured in the temperature range of 293.15 K to 343.15 K. Comparison of the mixtures prepared herein with the ones containing glycerol and choline chloride evidences the possibility of tuning the physico-chem. properties by changing the substitution pattern in the hydrogen bond donor compound or in the ammonium salt, thus broadening the scope of application of these mixtures

Physical Chemistry Chemical Physics published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Synthetic Route of 70445-33-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Marko, Monika published the artcileReal-life efficiency and safety comparison study of emollient ointment based on glycerophosphoinositol (GPI) salt of choline and other emollient products in patients with atopic dermatitis, Application In Synthesis of 70445-33-9, the publication is Journal of Dermatological Treatment (2022), 33(2), 999-1010, database is CAplus and MEDLINE.

Introduction The aim of this study was to investigate the effectiveness and safety of emollient preparations in comparison with the emollient ointment containing glycerophosphoinositol salt of choline in patients with atopic dermatitis (AD). Methods In a ‘real-life’ study, 300 patients with moderate AD were age-stratified and divided into two groups: patients applying GPI emollient and the comparator. We evaluated the effectiveness of AD treatment using: Eczema Area and Severity Index (EASI), Three Item Severity (TIS), Visual Analog Scale (VAS) and Four-Item Itch Questionnaire. Results The GPI emollient was superior in reduction AD symptoms in children: VAS (-2.58 ± 0.25), TIS (-2.22 ± 0.22), EASI (-15.27 ± 1.77), and adults: VAS (-2.42 ± 0.19), TIS (-2.22 ± 0.17), EASI (-13.22 ± 1.53), as compared to the other emollient in children: VAS (-0.67 ± 0.19), TIS (0.47 ± 0.19), EASI (-3.71 ± 1.01) and adults: VAS (-0.86 ± 0.09), TIS (0.77 ± 0.09), EASI (-2.95 ± 0.46), p < .001. Similar results were observed in Four Item Itch Questionnaire. Conclusion Both emollients showed good safety and tolerance profile and reduced AD symptoms. The GPI emollient seems to be more slightly effective in reducing AD symptoms as compared to the other com. available emollient.

Journal of Dermatological Treatment published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Application In Synthesis of 70445-33-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Rastogi, Supriya published the artcileAllergic contact dermatitis to personal care products and topical medications in adults with atopic dermatitis, COA of Formula: C11H24O3, the publication is Journal of the American Academy of Dermatology (2018), 79(6), 1028-1033.e6, database is CAplus and MEDLINE.

Atopic dermatitis (AD) is associated with skin-barrier disruption, immune dysregulation, and application of emollients and topical medications that might predispose a person toward developing allergic contact dermatitis. To determine the predictors of allergic contact dermatitis and relevant allergens in AD. A retrospective chart review was performed for 502 adults (age ≥18 years) who were patch tested to an expanded allergen series during 2014-2017. Overall, 108 (21.5%) had current AD and 109 (21.7%) had past AD. Patients with and without current AD had similar proportions of any pos. (+, ++, or +++ 80 [74.1%] vs 254 [64.5%], resp., chi-squared P = .06); strong-pos. (++ and +++ 34 [31.5%] vs 102 [25.9%], resp., P = .25); and irritant (56 [51.9%] vs 188 [47.7%], resp., P = .45) patch-test reactions. AD patients had significantly higher rates of pos. reactions to ingredients in their personal care products and topical medications, including fragrance mix II (P = .04), lanolin (P = .03), bacitracin (P = .04), cinnamal (P = .02), budesonide (P = .01), tixocortol (P = .02), and chlorhexidine (P = .001); relevance was established in >90% of these reactions. Polysensitization occurred more commonly in patients with AD than without (35 [32.4%] vs 75 [19.0%]; P = .01). Study was performed at a single center. AD patients had more pos. patch-test reactions to ingredients in their personal care products, topical steroids, and antibiotics.

Journal of the American Academy of Dermatology published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, COA of Formula: C11H24O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ricciardi, Maria published the artcileFirst Attempt of Glycidol-to-Monoalkyl Glyceryl Ethers Conversion by Acid Heterogeneous Catalysis: Synthesis and Simplified Sustainability Assessment, Name: 3-((2-Ethylhexyl)oxy)propane-1,2-diol, the publication is ChemSusChem (2018), 11(11), 1829-1837, database is CAplus and MEDLINE.

The selective preparation of monoalkylglyceryl ethers (MAGEs) is a task for researchers owing to their broad range of applications. In this work, green feedstocks such as glycidol and alcs. were used to prepare MAGEs under mild reaction conditions (80 °C, 3 h, 0.5 mol % catalyst) in the presence of acid heterogeneous catalysts. Nafion shows the best performances in terms of conversion and selectivity to MAGES and also high stability. A comparison of the environmental performances with the most consolidated pathway from glycerol has shown that the usage of glycidol (recovered as a value-added product from Epicerol process) and Nafion leads to a lower impact on ecosystems. In addition, results achieved from a simplified socio-economic anal. show that the innovative route here proposed has potential (at the laboratory scale) of enhancing potential gains and of reducing the social implications resulting from externalities associated with environmental impacts (e.g., CO₂ equivalents).

ChemSusChem published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Name: 3-((2-Ethylhexyl)oxy)propane-1,2-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Fukuda, K. published the artcileMicroemulsion formed by alkyl polyglucoside and an alkyl glycerol ether with weakly charged films, Quality Control of 70445-33-9, the publication is Colloids and Surfaces, B: Biointerfaces (2001), 20(2), 129-135, database is CAplus and MEDLINE.

We have studied the effects on phase equilibrium of a nonionic surfactant mixture-water-oil system when replacing small amount of surfactant mols. by ionic surfactant, sodium dodecyl sulfate (SDS). The nonionic surfactant system contains dodecyl-β-D-maltoside (C₁₂AG2) and isooctyl glyceryl ether (i-C₈GE) as cosurfactant, water and cyclohexane at constant water to oil ratio of 60/40 (weight/weight). Adding a small amount of SDS has large impact on the phase behavior. Clear liquid crystalline phase and upper microemulsion phase are added to the phase sequence at high i-C₈GE/(C₁₂AG2+i-C₈GE) ratio. We also compare the phase equilibrium of pure dodecyl maltoside system with polyglucosides mixture system.

Colloids and Surfaces, B: Biointerfaces published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Quality Control of 70445-33-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts