Category: 702-23-8

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, COA of Formula: C9H12O2702-23-8, Name is 2-(4-Methoxyphenyl)ethanol, SMILES is COC1=CC=C(CCO)C=C1, belongs to alcohols-buliding-blocks compound. In a article, author is Cai, Dongren, introduce new discover of the category.

Design and synthesis of novel amphipathic ionic liquids for biodiesel production from soapberry oil

Biodiesel produced from non-edible oils has received intensive attention in recent years. Herein, a series of novel amphipathic ionic liquids (ILs) based on the 4-dimethylaminopyridine (DMAP) were prepared for the transesterification of soapberry oil and methanol. The structures of the prepared ILs were systematically characterized by both Fourier transform infrared spectroscopy (FT-IR) and nuclear magnetic resonance (NMR, H-1 NMR and C-13 NMR). In addition, the effects of side-chain length of cation and the number of active site (H+) of ILs on the biodiesel yield were investigated, and the results suggested that 1-dodecyl-(4-dimethylammonium)-pyridinium bisulfate ([C12-DMAPH][HSO4](2)) exhibited the highest catalytic efficiency. Meanwhile, [C12-DMAPH][HSO4](2) was proven to be amphipathic, and the corresponding catalytic mechanism was proposed. Under the catalysis of [C12-DMAPH][HSO4](2), the optimum operating conditions of transesterification of soapberry oil and methanol were explored via the combination of single factor experiment and response surface methodology, obtaining the high biodiesel yield of (98.02 +/- 0.36)% under the optimum operating conditions. Importantly, [C12-DMAPH][HSO4](2) exhibited high stability in the transesterification of soapberry oil and methanol in five consecutive runs. Furthermore, the catalytic activities of [C12-DMAPH][HSO4](2) towards other transesterification of non edible oils and lower alcohols were also investigated, which indicated a general applicability of the prepared IL. (c) 2020 Elsevier Ltd. All rights reserved.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 702-23-8. COA of Formula: C9H12O2.

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Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Computed Properties of C9H12O2, 702-23-8, Name is 2-(4-Methoxyphenyl)ethanol, molecular formula is C9H12O2, belongs to alcohols-buliding-blocks compound. In a document, author is Imanova Yaghji, Narimana, introduce the new discover.

Hydroxychloroquine Sulfate Related Hypoglycemia In A Non-Diabetic COVID-19 Patient: A Case Report and Literature Review

Objective: Hypoglycemia is a serious adverse effect of hydroxychloroquine (HCQ) which is very rare in non-diabetic patients. This case report describes a non-diabetic patient without any other chronic diseases, who experienced mild hypoglycemia related to HCQ used for COVID-19 treatment. Methods: All etiologies causing hypoglycemia were investigated and a 72-hour fast test was performed. Results: A 34-year-old male patient was admitted to our hospital with a high fever, cough, and chest pain. The result of his COVID-19 PCR test was positive. He received HCQ for 10 days for the treatment of COVID-19 infection. He experienced fatigue, dizziness, severe headache, weakness and feeling of hunger after discontinuation of HCQ during his isolation at home. Before COVID-19 infection, he never experienced hypoglycemia symptoms. He did not have a history of chronic diseases, drug use, alcohol consumption, or smoking. A 72-hour fasting test was performed. He complained about headache and weakness during the 72-hour test period. The PG level was determined as 49 mg/dl during these symptoms. Concurrent insulin and C-peptide levels were <2 mU/mL and 0.553 ng/mL, respectively. ACTH, cortisol, growth hormones, liver and kidney function tests were normal. HbA1c level was 4.7% (28 mmol/mol) (Normal Range %4,5-5,7). Conclusion: Hypoglycemia may be observed as an adverse effect of HCQ used for COVID-19 infection even in patients without chronic diseases and comorbidities. We must be careful while using HCQ for these patients and must warn them about this effect. The warning about hypoglycemia effect of HCQ must be added to COVID-19 treatment guidelines. A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 702-23-8. Computed Properties of C9H12O2.

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Application of 702-23-8, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 702-23-8, Name is 2-(4-Methoxyphenyl)ethanol, SMILES is COC1=CC=C(CCO)C=C1, belongs to alcohols-buliding-blocks compound. In a article, author is Perez, Maria Jorgelina, introduce new discover of the category.

Interest of black carob extract for the development of active biopolymer films for cheese preservation

The aim of this work was to develop bio-based packaging materials based on black carob extracts (BCE) and kappa-carrageenan (kappa-c) blends, and to study their impact for cheese preservation. Firstly, black carob extracts were obtained with and without alcohol pre-treatment (BCE-a and BCE-b), respectively, and its chemical composition and antioxidant properties was analysed. Protein and polyphenol contents were higher in the extract without alcohol pre-treatment (BCE-b). Different bio-based films were prepared by mixing BCEs with kappa-c at different ratios, and the morphological, thermal, mechanical and water barrier properties of the films were evaluated. The antioxidant efficacy of BCE:kappa-c films prepared with both BCE extracts was further compared when applied on the preservation of cheese slides. Results showed that skipping the ethanolic extraction pre-treatment gave rise to more ductile films due to the presence of sucrose and other small sugars or the higher protein content in the BCE-b extract, which could have a plasticizer effect on the biopolymer network. Mixtures with kappa-c increased the rigidity of the films. A good correlation between barrier properties of films and the antioxidant efficacy on cheese samples was observed, suggesting that not only the antioxidant properties but also the physicochemical properties of the films had a direct impact on cheese quality and preservation. Films prepared with both BCEs at 50:50 BCE:kappa-c ratio and those prepared with BCE-a at 25:75 BCE:kappa-c ratio, presented good antioxidant capacity and a good compromise for physicochemical properties. However, from the economical point of view, 50:50 BCE-b:kappa-c films are more suitable since the extraction protocol of BCE-b was simpler and the yield was three-fold higher.

Application of 702-23-8, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 702-23-8.

Reference:
Alcohol – Wikipedia,
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Synthetic Route of 702-23-8, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 702-23-8, Name is 2-(4-Methoxyphenyl)ethanol, SMILES is COC1=CC=C(CCO)C=C1, belongs to alcohols-buliding-blocks compound. In a article, author is Zeng, Chuantao, introduce new discover of the category.

The expression profiles of acid-stable alpha-amylase and acid-labile alpha-amylase of Aspergillus luchuensis mut. Kawachii effect on the microstructure of koji and alcohol fermentation

We investigated the contribution of the complex expressions of two alpha-amylases, namely acid-stable alpha-amylase (AS-amylase) and acid-labile alpha-amylase (AL-amylase), from Aspergillus kawachii to the microstructure of koji and the brewing. AL-amylase was found to be the primary contributor to the decomposition of starch in the early stage of koji making. From the middle stage, both alpha-amylases decomposed the starch in a coordinated manner, and at the final stage, acid-stable alpha-amylase and glucoamylase decomposed the starch granules. Characterization of koji prepared by the single disruptions of AS-amylase or AL-amylase genes, double disruption of both alpha-amylase genes, and triple disruption of two alpha-amylase and glucoamylase genes in A. kawachii cells indicated that both alpha-amylases can work in a synergistic manner to decompose starches during koji making. AL-amylase was found, for the first time, to play an important role in starch decomposition in koji. The speed of alcohol fermentation and ester contents of the fermented mash were higher the mash prepared the control strain, followed by single, double, and triple disruptants. These results indicate that the microstructure of koji plays a role in promoting alcohol fermentation and flavor development.

Synthetic Route of 702-23-8, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 702-23-8.

Reference:
Alcohol – Wikipedia,
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Synthetic Route of 702-23-8, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 702-23-8, Name is 2-(4-Methoxyphenyl)ethanol, SMILES is COC1=CC=C(CCO)C=C1, belongs to alcohols-buliding-blocks compound. In a article, author is Xin, Yue, introduce new discover of the category.

Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice

Alcoholic liver disease (ALD) occurs as a result of chronic and excessive alcohol consumption. It encompasses a wide spectrum of chronic liver abnormalities that range from steatosis to alcoholic hepatitis, progressive fibrosis and cirrhosis. Endoplasmic reticulum (ER) stress induced by ethanol metabolism in hepatocytes has been established as an important contributor to the pathogenesis of ALD. However, whether SIRT6 exerts regulatory effects on ethanol-induced ER stress and contributes to the pathogenesis of ALD is unclear. In this study, we developed and characterized Sirt6 hepatocyte-specific knockout and transgenic mouse models that were treated with chronic-plus-binge ethanol feeding. We observed that hepatic Sirt6 deficiency led to exacerbated ethanol-induced liver injury and aggravated hepatic ER stress. Tauroursodeoxycholic acid (TUDCA) treatment remarkably attenuated ethanol-induced ER stress and ameliorated ALD pathologies caused by Sirt6 ablation. Reciprocally, SIRT6 hepatocyte-specific transgenic mice exhibited reduced ER stress and ameliorated liver injury caused by ethanol exposure. Consistently, knockdown of Sirt6 elevated the expression of ER stress related genes in primary hepatocytes treated with ethanol, whereas overexpression of SIRT6 reduced their expression, indicating SIRT6 regulates ethanol-induced hepatic ER stress in a cell autonomous manner. Collectively, our results suggest that SIRT6 is a positive regulator of ethanol-induced ER stress in the liver and protects against ALD by relieving ER stress. (C) 2021 Elsevier Inc. All rights reserved.

Synthetic Route of 702-23-8, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 702-23-8.

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Application of 702-23-8, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.702-23-8, name is 2-(4-Methoxyphenyl)ethanol, molecular formula is C9H12O2, molecular weight is 152.19, as common compound, the synthetic route is as follows.

To a solution of 4-methoxyphenethyl alcohol (1.03 g, 6.77 mmol) in dichloromethane (20 mL) were added N,N-diisopropylethylamine (2.3 mL, 14 mmol) and chloromethyl methyl ether (0.82 mL, 11 mmol) at 0 C. The reaction mixture was stirred for 27 h at ambient temperature. The reaction mixture was then concentrated under reduced pressure. Column chromatography (silica gel, 34 g; n-hexane/ethyl acetate, 8:1) gave the title compound (1.19 g, 6.07 mmol, 89.6%) as a pale yellow oil. 1 H NMR (400 MHz, CDCl 3 ): delta 2.85 (t, J = 7.0 Hz, 2H), 3.30 (s, 3H), 3.72 (t, J = 7.0 Hz, 2H), 3.78 (s, 3H), 4.61 (s, 2H), 6.80-6.87 (m, 2H), 7.12-7.19 (m, 2H). 13 C NMR (100 MHz, CDCl 3 ): delta 35.5, 55.3, 55.4, 68.8, 96.5, 113.9, 129.9, 131.1, 158.2. HR-MS (EI): Calcd for C 11 H 16 O 3 [M] + : 196.1099. Found: 196.1093. IR (neat, cm -1 ): 2936, 2836, 1613, 1514, 1247.

Statistics shows that 702-23-8 is playing an increasingly important role. we look forward to future research findings about 2-(4-Methoxyphenyl)ethanol.

Reference:
Article; Karaki, Fumika; Kuwada, Miki; Tajiri, Saki; Kanda, Misaki; Yanai, Mari; Kamimura, Mitsuhiro; Itoh, Kennosuke; Fujii, Hideaki; Synthetic Communications; vol. 49; 2; (2019); p. 212 – 220;,
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Electric Literature of 702-23-8, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 702-23-8, name is 2-(4-Methoxyphenyl)ethanol. A new synthetic method of this compound is introduced below.

PREPARATION F 4-(3-[p-Methoxyphenyl]propyl)pyridine To a stirred solution of 3.04 g. of 2-(p-methoxyphenyl)ethanol in 10 ml. of benzene, is added dropwise, a solution of 0.72 ml. of phosphorus tribromide in 10 ml. of benzene, at ambient temperature. The mixture is then heated at 60C. for 1 hour. After being cooled to ambient temperature again, the reaction mixture is poured onto 50 g. of crushed ice. A small amount of ether is added, and then the organic phase is separated off, washed sequentially with 0.5N sodium hydroxide and water, and evaporated to dryness. This affords 2.8 g. of 2-(p-methoxyphenyl)ethyl bromide as an oil.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,702-23-8, 2-(4-Methoxyphenyl)ethanol, and friends who are interested can also refer to it.

Reference:
Patent; Pfizer Inc.; US3983107; (1976); A;,
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702-23-8, Adding a certain compound to certain chemical reactions, such as: 702-23-8, 2-(4-Methoxyphenyl)ethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 702-23-8, blongs to alcohols-buliding-blocks compound.

General procedure: 5.1.57.3. Step 3. To a solution of 2-(3-fluorophenyl)ethanol(25.26 g, 180 mmol) in pyridine (180 mL) was added TsCl(36.49 g, 186 mmol) at 0 C with silica gel blue tube. After stirringat rt for 4 h, the reaction was quenched by the addition of 2 N HCl (750 mL) at 0 C. This mixture was extracted with EtOAc (300 mL).The separable organic layer was washed with 2 N HCl (250 mL),H2O (200 mL), brine (100 mL), and dried over MgSO4, filtered, concentratedunder reduced pressure. The residue was purified by columnchromatography (SiO2, n-hexane/EtOAc = 10/1-5/1) to obtain2-(3-fluorophenyl)ethyl 4-methylbenzenesulfonate (38.54 g, 73%)as a colorless oil.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,702-23-8, its application will become more common.

Reference:
Article; Imaeda, Toshihiro; Ono, Koji; Nakai, Kazuo; Hori, Yasunobu; Matsukawa, Jun; Takagi, Terufumi; Fujioka, Yasushi; Tarui, Naoki; Kondo, Mitsuyo; Imanishi, Akio; Inatomi, Nobuhiro; Kajino, Masahiro; Itoh, Fumio; Nishida, Haruyuki; Bioorganic and Medicinal Chemistry; vol. 25; 14; (2017); p. 3719 – 3735;,
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In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 702-23-8 as follows., 702-23-8

In a three-neckflask, 2-(4-methoxyphenyl)ethanol (2a, 3.00 g, 1 eq.) andtriphenylphosphine (6.72 g, 1.3 eq.) were dissolved in dryCH2Cl2 (25 ml). In an addition funnel, carbon tetrabromide(8.50 g, 1.3 eq.) was dissolved in dry CH2Cl2 (15 ml) andadded dropwise under inert atmosphere at 0 C until theaddition was complete. The reaction was allowed to stirat room temperature for an additional 4 h, or until completedisappearance of starting materials from thin-layerchromatography (TLC). The solvent was removed underreduced pressure, and the residue was purified by column chromatography using hexane and EtOAc to yield 3a as aclear oil. Yield: 4.11 g (97 %). 1H NMR (CDCl3) delta (ppm):3.08-3.12 (t, 2H), 3.51-3.55 (t, 2H), 3.79 (s, 3H), 6.85-6.87 (d, 2H), 7.12-7.14 (d, 2H).

The chemical industry reduces the impact on the environment during synthesis 702-23-8, I believe this compound will play a more active role in future production and life.

Reference:
Article; Do, Quang; Nguyen, Giang T.; Phillips, Robert S.; Amino Acids; vol. 48; 9; (2016); p. 2243 – 2251;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts