Category: 65-22-5

New dioxidouranium (VI) and mixed-valence oxidovanadium (IV/V) coordination compounds with N,O-pentadentate ligands obtained from pyridoxal and triethylenetetramine was written by Back, Davi Fernando;de Oliveira, Gelson Manzoni;Fontana, Liniquer Andre;Neves, Ademir;Iglesias, Bernardo Almeida;Camargo, Tiago Pacheco;Campos, Patrick Teixeira;Vargas, Jaqueline Pinto. And the article was included in Inorganica Chimica Acta in 2015.Synthetic Route of C8H10ClNO3 The following contents are mentioned in the article:

This work describes the synthesis and structural anal. of the uranium and vanadium complexes [(UO₂)(C₂₂H₃₀N₆O₄)]·MeOH (1) and [(VO)₂(O)(C₃₀H₃₆N₇O₆)]·3MeOH (2) with ligands obtained from the condensation of pyridoxal and triethylenetetramine. The probable mechanism for the formation of imidazoline rings in these complexes is described in some details. Finally, electrochem. and UV-visible studies of the dinuclear vanadium complex were also carried out to determine the variation in the oxidation states of the metallic centers (VO²⁺/VO³⁺) in DMSO solution This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Synthetic Route of C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Synthetic Route of C8H10ClNO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

N,N’-dipyridoxyl(1,2-diaminocyclohexane) and its Cu(II) complex: Synthesis, experimental and theoretical studies was written by Beyramabadi, S. A.;Morsali, A.;Shams, A.. And the article was included in Journal of Structural Chemistry in 2015.Recommanded Product: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:

The N,N’-dipyridoxyl(1,2-diaminocyclohexane) [=H₂L] Schiff-base ligand and its square complex [Cu(L)] are newly synthesized and characterized by IR, mass spectroscopy, ¹H NMR, and elemental anal. The full optimization of geometries, the ¹H NMR chem. shifts (for the H₂L) and their vibrational frequencies are calculated using the d. functional theory (DFT) method. The optimized geometry of the ligand is not planar, but each of two pyridine rings and the cyclohexane moiety are in the sep. planes. The tetradentate-dianionic L^2- ligand occupies the four coordination positions of the square complex in the N, N, O^–, O^– manner. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Recommanded Product: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chemically modified cellulose strips with pyridoxal conjugated red fluorescent gold nanoclusters for nanomolar detection of mercuric ions was written by Bothra, Shilpa;Upadhyay, Yachana;Kumar, Rajender;Ashok Kumar, S. K.;Sahoo, Suban K.. And the article was included in Biosensors & Bioelectronics in 2017.Application of 65-22-5 The following contents are mentioned in the article:

One-pot approach was adopted for the synthesis of highly luminescent near-IR (NIR)-emitting gold nanoclusters (AuNCs) using bovine serum albumin (BSA) as a protecting agent. The vitamin B₆ cofactor pyridoxal was conjugated with the luminescent BSA-AuNCs through the free amines of BSA and then employed for the nanomolar detection of Hg²⁺ in aqueous medium via selective fluorescence quenching of AuNCs. This nano-assembly was successfully applied for the real sample anal. of Hg²⁺ in fish, tap water and river water. The study also presents chem.-modified cellulosic paper strips with the pyridoxal conjugated BSA-AuNCs for detecting Hg²⁺ ion up to 1 nM. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Application of 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application of 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Syntheses, crystal structures, spectral studies, and DFT calculations of two new square planar Ni(II) complexes derived from pyridoxal-based Schiff base ligands was written by Mandal, Senjuti;Chatterjee, Sudipta;Modak, Ritwik;Sikdar, Yeasin;Naskar, Barnali;Goswami, Sanchita. And the article was included in Journal of Coordination Chemistry in 2014.Synthetic Route of C8H10ClNO3 The following contents are mentioned in the article:

Two new complexes based on a Schiff base derived from pyridoxal N,N-dimethylethylenediamine (HL¹) and N,N-diethylethylenediamine (HL²), [Ni(L¹)SCN] and [Ni(L²)SCN], were synthesized and structurally characterized by single-crystal x-ray diffraction along with other phys. techniques, including elemental analyses, IR spectra, cyclic voltammetry, UV-visible, and luminescence studies. X-ray studies suggest that in both the complexes Ni lies in a slightly distorted square planar environment occupied by the tridentate ONN ligand and an isothiocyanate moiety. D. functional theory computations were carried out to characterize the complexes. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Synthetic Route of C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Synthetic Route of C8H10ClNO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A rapid and naked-eye visible rhodamine 6G-based chemosensor for sensitive detection of copper(II) ions in aqueous solution was written by Huang, Q.;Chen, Y. T.;Ren, Y. W.;Wang, Z. Y.;Zhu, Y. X.;Zhang, Y.. And the article was included in Analytical Methods in 2018.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:

A new rhodamine 6G derivative (R6GHP) has been synthesized for quick recognition of copper(II) ions (Cu2+) in aqueous solutions The structure of R6GHP has been characterized by NMR and electrospray ionization mass spectrometry. Upon binding of Cu2+, the fluorescence intensity remarkably increases with about 36-fold enhancement. In addition, the color change from colorless to pink is visible to the naked eye. In optimal conditions, the fluorescence intensity and absorbance of R6GHP show good linearity with concentration of Cu2+ in the ranges of 1.0 × 10-6 to 1.0 × 10-5 mol L-1 and 1.0 × 10-6 to 1.2 × 10-5 mol L-1, resp., with detection limits of 3.9 × 10-7 mol L-1 and 1.0 × 10-6 mol L-1. Besides, it has been successfully applied to detect Cu2+ in two water samples. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Syntheses, crystal structures and spectroscopic characterization of two new octahedral nickel(II) complexes of a Schiff base ligand derived from pyridoxal and 2-(pyrid-2-yl)ethylamine was written by Mandal, Senjuti;Modak, Ritwik;Sikdar, Yeasin;Naskar, Barnali;Goswami, Sanchita. And the article was included in Journal of Molecular Structure in 2014.Product Details of 65-22-5 The following contents are mentioned in the article:

Two new coordination compounds based on ONN donor Schiff base ligand derived from pyridoxal and 2-(pyrid-2-yl)ethylamine, namely {[Ni(HL)(H₂O)₂](ClO₄)₂}_∞ (1) and [Ni(HL)(H₂O)(SCN)₂] (2) have been synthesized and structurally characterized by single-crystal x-ray diffraction along with other phys. techniques, including elemental anal., IR spectra and UV-visible studies. X-ray studies suggest that both 1 and 2 are mononuclear nickel(II) complexes and exhibit distorted octahedral geometry. In these compounds the pyridoxal based Schiff base ligand displays different coordination modes constructing various architectures. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Product Details of 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Product Details of 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pro-oxidant activity of nickel (II) pyridoxal complexes. Synthesis, characterization and peroxidase activity assays was written by Fontana, Liniquer Andre;Stuker, Monica;Oliveira, Gelson Manzoni;Iglesias, Bernardo Almeida;Back, Davi Fernando. And the article was included in Inorganic Chemistry Communications in 2015.Related Products of 65-22-5 The following contents are mentioned in the article:

The synthesis of Ni(II) complexes with pro-oxidant applications demonstrated many advantages, such as accelerated reactions, solution stability and with high selectivity reactions. The authors describe the synthesis, characterization and structural anal. of nickel ([Ni(L₁)], 1);([Ni(L₂)], 2) and ([Ni(HL₃)]Cl·DMF, 3) complexes with ligands obtained from the condensation of pyridoxal and aryl-thiol amines and their application as a pro-oxidant in the reaction of the phenol-aminoantipyrine adduct. The complexes show variation in carbon spacers between pyridoxal mols.: ethane, propane and butane. The spacer two carbons containing the most significant as the pro-oxidant activity. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Related Products of 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Related Products of 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis, characterisation and antibacterial activity of benzohydrazones derived from 3-hydroxy-5-hydroxymethyl-2-methylpyridine-4-carboxaldehyde was written by Ramdas, Kavitha;Sireesha, B.;Reddy, Ch. Venkata Ramana. And the article was included in Heterocyclic Letters in 2016.HPLC of Formula: 65-22-5 The following contents are mentioned in the article:

New Schiff bases I [R = 4-OH, 4-Cl, 4-Br, etc.] derived from 3-hydroxy-5-hydroxymethyl-2-methylpyridine-4-carboxaldehyde were synthesized and characterized by various spectro-anal. techniques like IR, ¹H-NMR, ¹³C-NMR and mass spectroscopy. The compounds I were screened for their antibacterial activity against Gram neg. bacteria (Escherichia coli and Pseudomonas aeruginosa) and Gram pos. bacteria (Staphylococcus aureus and Bacillus cereus). Compounds I [R = 2,4-di-Cl] and [R = 3,4,5-tri-MeO] showed excellent antibacterial activity while compounds I [R = 4-OH, 4-F, 3-O₂N] showed good activity. The remaining compounds exhibited moderate activity. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5HPLC of Formula: 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.HPLC of Formula: 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Aryl ethers coupled pyridoxal as supramolecular gelator for selective sensing fluoride was written by Ghosh, Kumaresh;Pati, Chiranjit. And the article was included in Tetrahedron Letters in 2016.Synthetic Route of C8H10ClNO3 The following contents are mentioned in the article:

Aryl ethers coupled pyridoxal Schiff base 1 has been synthesized and its gelation properties have been examined The gelator 1 forms colorless gels from various solvents such as DMSO, DMF, DMSO/H₂O and DMF/H₂O. The gel matrix obtained from DMSO shows ribbon-like fibrous morphol. and has been utilized for efficient ‘naked eye’ detection of fluoride ion through a reversible gel-sol transition, which is associated with color change from almost colorless to yellow. In DMSO, the Schiff base 1 has also been observed to sense F^– ion more efficiently over the basic ions AcO^– and CN^–. Though few examples of anion sensing in solution with pyridoxal-based Schiff bases are known, anion recognition utilizing pyridoxal-based gelators is unexplored in the literature. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Synthetic Route of C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Synthetic Route of C8H10ClNO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Virtual screening of molecular properties of chitosan and derivatives in search for druggable molecules was written by Hassan, Basila;Shireen, Ajmala;Muraleedharan, K.;Mujeeb, V. M. Abdul. And the article was included in International Journal of Biological Macromolecules in 2015.SDS of cas: 65-22-5 The following contents are mentioned in the article:

Druggability of chitosan monomer and Schiff bases as well as reduced Schiff base derivatives of chitosan were examined Oral bioavailability and bioactivity of all these mols. against selected drug targets as well as ADME/Tox studies were conducted. All the mols. satisfied Lipinski’s rule of five confirming their oral bioavailability. They also show good bioactivity score for protease and enzyme inhibition. ADME/Tox studies conducted shows that almost all the derivatives are free from toxicity risks. It is observed that these mols. exhibit fairly good drug score and are orally viable mols. Chelation of chitosan and its derivatives with essential metal ions might be the mechanism driving their bioactivity. Thus chitosan monomer and the derivatives studied, can serve as good lead mols. for further research. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5SDS of cas: 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.SDS of cas: 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts