Category: 65-22-5

Novel pyridoxal based molecular sensor for selective turn-on fluorescent switching functionality towards Zn(II) in live cells was written by Karthick, Kettalu Ananthan;Kaleeswari, Kalairajan;Uma Maheswari, C.;Sivaraman, Gandhi;Shankar, Bhaskaran;Tamilselvi, Arunachalam. And the article was included in Journal of Photochemistry and Photobiology, A: Chemistry in 2022.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:

A new facile mol. sensor (HL), 4-((3-(cyclohexylamino)propylimino)methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, constructed with pyridoxal moiety, selectively detects Zn²⁺ ion in solid and solution medium. The structure of this newly synthesized sensor is confirmed by single crystal X-ray diffraction study. The rapid selective fluorescence ′turn-on′ response of Zn²⁺ ion in aqueous ethanolic (9:1, volume/volume) HEPES buffer (pH = 7.0) medium was studied. The synthesized mol. sensor shows the lowest limit of detection (LOD) for Zn²⁺ ion (9.5850 ± 0.3835 nM). The sensing behavior of the mol. sensor towards Zn²⁺ can be ascribed to the formation of complex. D. functional theory (DFT) and time dependent d. functional theory (TD-DFT) calculations were carried out to support the proposed tetrahedral geometry of zinc(II) complex and to explore the electronic properties of HL and its zinc complex (ZnL₂). The mol. sensor shows the practical application to detect zinc(II) qual. on TLC plate based test strips. In addition to that, it also gives insight into the design of protocols required for successful imaging of intracellular zinc(II) ions in HeLa cells. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

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Root metabolic plasticity underlies functional diversity in mycorrhiza-enhanced stress tolerance in tomato was written by Rivero, Javier;Alvarez, Domingo;Flors, Victor;Azcon-Aguilar, Concepcion;Pozo, Maria J.. And the article was included in New Phytologist in 2018.COA of Formula: C8H10ClNO3 The following contents are mentioned in the article:

Summary : Arbuscular mycorrhizal (AM) symbioses can improve plant tolerance to multiple stresses. We compared three AM fungi (AMF) from different genera, one of them isolated from a dry and saline environment, in terms of their ability to increase tomato tolerance to moderate or severe drought or salt stress. Plant physiol. parameters and metabolic profiles were compared in order to find the mol. mechanisms underlying plant protection against stress. Mycorrhizal growth response was determined, and ultrahigh-performance LC-MS was used to compare the metabolic profile of plants under the different treatments. All AMF increased plant tolerance to stress, and the pos. effects of the symbiosis were correlated with the severity of the stress. The AMF isolated from the stressful environment was the most effective in improving plant tolerance to salt stress. Differentially accumulated compounds were identified and the antistress properties of some of them were confirmed. We demonstrate that AM symbioses increase plant metabolic plasticity to cope with stress. Some responses were common to all AMF tested, while others were specifically related to particular isolates. Important metabolism reprograming was evidenced upon salt stress, and we identified metabolic pathways and compounds differentially accumulated in mycorrhizas that may underlie their enhanced tolerance to stress. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5COA of Formula: C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.COA of Formula: C8H10ClNO3

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Effect and mechanism of pyridoxamine on the lipid peroxidation and stability of polyunsaturated fatty acids in beef patties was written by Wong, Daniel;Hu, Xiaoqiang;Tao, Ningping;Wang, Xichang;Wang, Mingfu. And the article was included in Journal of the Science of Food and Agriculture in 2016.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:

BACKGROUND : Little is known about how vitamins can affect the peroxidation and stability of polyunsaturated fatty acids in cooked foods. Thus the effects of 15 vitamins on toxic malondialdehyde (MDA) formation in cooked beef patties were examined with the application of solid phase extraction and thiobarbituric acid (TBA) anal. by HPLC-DAD. The polyunsaturated fatty acid profiles in cooked beef patties treated with some vitamins were further compared with that of control sample (no vitamin addition) by GC-MS anal. RESULTS : Pyridoxamine, pyridoxine, retinoic acid, α-tocopherol and L-ascorbic acid exhibited significant effects lowering the amount of MDA. It was further discovered that retinoic acid, α-tocopherol and L-ascorbic acid could help preserve polyunsaturated fatty acids, while pyridoxamine addition actually showed no effect upon the retention of most of the tested polyunsaturated fatty acids, even lowering the content of arachidonic acid. Further LC-MS anal. demonstrated that pyridoxamine could directly react with MDA via an addition reaction. The reaction involves a nucleophilic attack of pyridoxamine’s free amine group on one of the aldehyde functional groups of MDA to form a new adduct, and may accelerate lipid peroxidation with the loss of more polyunsaturated fatty acids. CONCLUSION : Some vitamins may directly participate in lipid peroxidation and affect food quality. © 2015 Society of Chem. Industry. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

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New pyridoxal based chemosensor for selective detection of zinc ion: Application in live cell imaging and phosphatase activity response was written by Mandal, Senjuti;Sikdar, Yeasin;Maiti, Dilip K.;Sanyal, Ria;Das, Debasis;Mukherjee, Abhishek;Mandal, Sushil Kumar;Biswas, Jayanta Kumar;Bauza, Antonio;Frontera, Antonio;Goswami, Sanchita. And the article was included in Journal of Photochemistry and Photobiology, A: Chemistry in 2017.Reference of 65-22-5 The following contents are mentioned in the article:

Although a variety of fluorescence based chemosensors have been utilized for selective detection of Zn²⁺, pyridoxal containing simple Schiff bases still remained less explored. Here, we combine pyridoxal hydrochloride and 1,2-diaminocyclohexane to generate a new sensor mol., H4PydChda (5-Hydroxymethyl-4-((2-(5-hydroxymethyl-2-methylpyridin-3-hydroxy-4-ylethylene)-amino)-cyclohexylimino)-methyl-2-methylpyridin-3-ol). Chemosensor H₄PydChda exhibits selective turn-on type response in presence of Zn²⁺ in ethanol-water mixture at physiol. pH. Appreciable fluorescence enhancement occurs upon addition of Zn²⁺ to H₄PydChda as a result of inhibited C=N isomerisation and excited state intramol. proton transfer leading to efficient chelation enhanced fluorescence. The relevant properties, including reversibility, life time measurements and detection limit have been determined for the sensor system. The exptl. and theor. supports in terms of ¹H and ¹³C NMR spectroscopy and DFT/ TDDFT study are provided to establish the binding mode of H₄PydChda to Zn²⁺. H₄PydChda was employed as a sensor for detection of Zn²⁺ in Human gastric adenocarcinoma AGS cells. Moreover, the resulting probe-Zn²⁺complex shows convincing phosphatase activity k_cat = 21.59 s^-1 opening a promising avenue for further research. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Reference of 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Reference of 65-22-5

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Structural divergence in binuclear Cu(II) pyridoxal Schiff base complexes probed by co-ligands: catecholase mimetic activity and sulphide ion sensing was written by Chakraborty, Moumita;Mondal, Antu;Chattopadhyay, Shyamal Kumar. And the article was included in New Journal of Chemistry in 2020.Formula: C8H10ClNO3 The following contents are mentioned in the article:

Three hydroxymethyl bridged Cu(II) complexes of a pyridoxal Schiff base ligand 4-((E)-(2-(pyridin-2-yl)ethylimino)methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol (LH) were synthesized and characterized on the basis of spectroscopic, electrochem. and structural properties. The x-ray crystal structures of the complexes reveal dual denticity of the ligand, bidenticity in the absence of a co-ligand as in complex 1, and tridenticity in the presence of a co-ligand such as SCN^–/N(CN)₂^– as in complexes 2 and 3. The complexes, though binuclear in the solid state, exist as a monomeric unit in solution due to the exceptionally long axial Cu-O_{hydroxymethyl} (2.4-2.5 Å) bond. All three complexes show efficient catalytic activities towards the aerial oxidation of 3,5-di-tert-butylcatechol (DTBCH₂) with k_cat values of 5.38 x 10⁴ h^-1, 1.18 x 10⁵ h^-1 and 1.06 x 10⁵ h^-1 in methanol. Complexes 1 and 2 also act as a selective sulfide ion sensor with K_b values of 6.6 x 10³ M^-1 and 8.1 x 10³ M^-1, resp., while their resp. L.O.D. values are 3.4μM and 3.2μM. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Formula: C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Formula: C8H10ClNO3

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A new zinc(II) complex with N₂O₂-tetradentate Schiff-base derived from pyridoxal-S-methylthiosemicarbazone: Synthesis, characterization, crystal structure, DFT, molecular docking and antioxidant activity studies was written by Poladian, Qumars;Sahin, Onur;Karakurt, Tuncay;Ilhan-Ceylan, Berat;Kurt, Yasemin. And the article was included in Polyhedron in 2021.Electric Literature of C8H10ClNO3 The following contents are mentioned in the article:

A new unsym. N₂O₂-tetradentate Schiff-base complex of zinc(II) was synthesized by the template reaction of pyridoxal-S-methylthiosemicarbazone and 2-hydroxy-4-methoxy-benzaldehyde as starting compounds S-methylthiosemicarbazone (1) and zinc(II) complex [Zn(L)CH₃OH] (2) were characterized by elemental anal., FT-IR, UV-visible, ¹H, and ¹³C NMR spectra. The mol. structure of 2 was determined by single crystal X-ray diffraction technique. The structure consists of a distorted square-pyramidal geometry around the central metal, Zn(II). Quantum chem. calculations were carried out using d. functional theory DFT/B3LYP, 6-31G (d), and LanL2DZ basis sets for theor. characterization of the compounds The exptl. and theor. data were compared comprehensively. The potential energy distribution (PED) anal. was performed for the assignment of vibration frequencies. In order to support in vitro studies, mol. docking studies were carried out so that the title compound can be an inhibitor of Epidermal Growth Factor Receptor (1 m17), and the relationship between calculated HOMO energies and docking studies was examined In addition, the total antioxidant capacity (as TEAC value) and free radical scavenging activity of the compounds were determined by Cupric Reducing Antioxidant Capacity (CUPRAC) and 1,1-diphenyl-2-picryl hydrazyl (DPPH) methods, resp. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Electric Literature of C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Electric Literature of C8H10ClNO3

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Pyridoxal hydrochloride thiosemicarbazones with copper ions inhibit cell division via Topo-I and Topo-II was written by Qi, Jinxu;Zheng, Yunyun;Li, Bin;Ai, Yu;Chen, Mengyao;Zheng, Xinhua. And the article was included in Journal of Inorganic Biochemistry in 2022.Synthetic Route of C8H10ClNO3 The following contents are mentioned in the article:

Topoisomerase (Topo) accelerates cell growth and division, and has been a theor. target for anti-cancer drugs for decades. A series of pyridoxal thiosemicarbazone (PLT) ligands were designed and synthesized, and the dependence of their antiproliferative activity on copper was investigated. The insertion of N-cyclohexyl-2-((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)-N-methylhydrazinecarbothioamide hydrochloride (compound 9) and Chlorido(N-cyclohexyl-2-((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)-N-methylhydrazinecarbothioamide hydrochloride-O,N,S)-copper(II) nitrate (9-Cu complex) into Topo-I and Topo-II prevented uncoiling of DNA through hydrogen bonds and intermol. forces. The combination of PLT derivatives and copper gluconate (CuGlu) improved their anti-tumor activity against a cell line with high expression of topoisomerase (SK-BR-3). The non-linear regression equations of the inhibitory activity and anti-tumor activity of Topo-I and Topo-II in SK-BR-3 cells had R2 values of 0.93 and 0.94, resp. In addition to lipophilicity, inhibition of topoisomerase also affected the activity of PLT ligands by coordinating with copper ions. At the cellular level, PLTs and CuGlu penetrate the cell membrane to form metabolites in the cell, thus selectively inhibiting the activity of Topo-I and Topo-II, and ultimately inhibiting cell division. These findings will inform the design of future anti-cancer thiosemicarbazone drugs. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Synthetic Route of C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Synthetic Route of C8H10ClNO3

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A Co(II) complex of a vitamer of vitamin B₆ acts as a sensor for Hg²⁺ and pH in aqueous media was written by Sing, Nilam;Roy, Sanjay;Guin, Partha Sarathi;Mahali, Kalachand;Majee, Prakash;Mondal, Sudip Kumar;Mahata, Partha;Sengupta, Partha Sarathi;Mondal, Palash. And the article was included in New Journal of Chemistry in 2016.Quality Control of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:

A Co(II) complex of mol. formula C₂₄H_48.4N₆O_11.2CoCl, 1 CoL₂·7.2H₂O·Cl, was synthesized from the Schiff base [H₂pydmdp]Cl by a template reaction of pyridoxal (pyd), a vitamer of vitamin B₆, N-methyl-1,3-diaminopropane (mdp) and cobalt(II) acetate. It was characterized by elemental anal., ¹H NMR, IR and UV-visible spectroscopy, thermal anal., electrochem. and single crystal x-ray diffraction. The exptl. results suggested that in complex 1, the central Co(II) is bonded to two phenolato-oxygens, two imine nitrogens and two amine nitrogens in an octahedral geometry. In aqueous media complex 1 exhibits an intense fluorescence emission peak at 506 nm when it was excited at 425 nm. The fluorescence behavior of complex 1 in aqueous media was employed to determine whether it acts as a chemosensor for some selective toxic metal ions. The present complex behaves as a promising sensor for Hg²⁺ even at the sub-micromolar level. In addition in aqueous solution, complex 1 acts as a sensor for the pH of the medium. A detailed study on the mechanism of sensing behavior established that Hg²⁺ interacts with complex 1 via weak noncovalent interaction with the N-atom of the pyridine moiety of the mol. The pyridine nitrogen also plays a vital role in sensing the pH of the medium. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Quality Control of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Quality Control of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

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Iron(III) and cobalt(III) complexes with pentadentate pyridoxal Schiff base ligand – structure, spectral, electrochemical, magnetic properties and DFT calculations was written by Muraskova, Viera;Eigner, Vaclav;Dusek, Michal;Sedmidubsky, David. And the article was included in Polyhedron in 2021.SDS of cas: 65-22-5 The following contents are mentioned in the article:

Three complexes, [FeLCl]Cl·H₂O, [Co₂L₂H₃O₂]Cl·4.8H₂O, and [CoLN₃], where L^2- is the dianion of an asym. propyl-Et pentadentate Schiff base ligand condensed from pyridoxal and N-(2-aminoethyl)propane-1,3-diamine, have been synthesized and characterized by elemental anal., FTIR and mass spectroscopy. Crystal structures of the complexes along with the Schiff base were determined by x-ray diffraction. ¹HNMR spectrum of the Schiff base has been obtained. The coordination polyhedra of all three complexes can be expressed as distorted octahedra. Magnetic investigations of [FeLCl]Cl·H₂O complex confirmed high-spin state over the whole temperature range (5-300 K) and allowed the evaluation of the axial zero-field splitting (ZFS) parameter D = -0.97 cm^-1, intermol. exchange parameter zj ́= -0.88 cm^-1 and temperature-independent paramagnetism χ_TIM = 0.00025 cm³mol^-1. The low-spin state of Co(III) was stabilized in diamagnetic [Co₂L₂H₃O₂]Cl·4.8H₂O and [CoLN₃] complexes. Redox potentials of the Schiff base and the complexes were investigated by cycling voltammetry on the GC electrode in dry acetonitrile. The exptl. magnetic properties of the complexes [FeLCl]Cl·H₂O and [CoLN₃] were compared with the theor. ones calculated using d. functional theory (DFT). This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5SDS of cas: 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.SDS of cas: 65-22-5

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Complexes of pyridoxal thiosemicarbazones formed with vanadium(IV/V) and copper(II): Solution equilibrium and structure was written by Jakusch, Tamas;Kozma, Karoly;Enyedy, Eva A.;May, Nora V.;Roller, Alexander;Kowol, Christian R.;Keppler, Bernhard K.;Kiss, Tamas. And the article was included in Inorganica Chimica Acta in 2018.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:

The stoichiometry and thermodn. stability of vanadium(IV/V) and copper(II) complexes of pyridoxal thiosemicarbazone and pyridoxal-N³,N³-dimethylthiosemicarbazone were determined by pH-potentiometry (V^IVO), EPR (V^IVO/Cu^II), UV-visible (Cu^II, V^IVO and V^V) and ⁵¹V NMR spectroscopy (V^V) in 30% (weight/weight) DMSO/water solvent mixture In all cases, mono-ligand complexes are formed in different protonation states. In addition, the proton-dissociation constants of the ligands were also determined by pH-potentiometry, UV-visible and ¹H NMR spectroscopy. The solid state structures of the monoprotonated forms (V^VO₂(L¹H)×1.5H₂O) (1) and (V^VO₂(L²H)×0.8H₂O) (2) of the V^V complexes were characterized by single-crystal x-ray diffraction anal. The mono-ligand complexes of Cu^II and V^V are dominant at physiol. pH. With all studied metal ions the pyridoxal moiety of the ligand causes an extra deprotonation step between pH 4 and 7 due to the non-coordinating pyridine-NH⁺. The pyridoxal-containing ligands form somewhat more stable complexes with both V^IVO and Cu^II ions than the reference compound salicylaldehyde thiosemicarbazone. Dimethylation of the terminal amino group gave V^V and Cu^II complexes with even higher stability. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

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