Category: 6351-10-6

Application of 6351-10-6, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 6351-10-6, name is 2,3-Dihydro-1H-inden-1-ol. A new synthetic method of this compound is introduced below.

General procedure: A mixture of alcohol 1a (100 mg, 0.54 mmol), alkene 2a (43 mg, 0.54 mmol), Ca(OTf)2 (18.3 mg, 0.05 mmol),Bu4NPF6 (21 mg, 0.05 mmol) was heated under solvent free condition at 70C for 1.5 h until complete consumption of the starting material as monitored by TLC. After the completion of the reaction the mixture was purified by flash column chromatography (petroleum ether) to afford the desired product 3a.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,6351-10-6, its application will become more common.

Reference:
Article; Yaragorla, Srinivasarao; Pareek, Abhishek; Dada, Ravikrishna; Almansour, Abdulrahman I.; Arumugam, Natarajan; Tetrahedron Letters; vol. 57; 52; (2016); p. 5841 – 5845;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 6351-10-6, name is 2,3-Dihydro-1H-inden-1-ol, the common compound, a new synthetic route is introduced below. name: 2,3-Dihydro-1H-inden-1-ol

General procedure: A mixture of alcohol or phenol (1 mmol), DHP (1.2-1.4 mmol), and MNPs-PSA (5 mg, 0.95 mol%) was stirred at room temperature in dry CH2Cl2 (2 mL), and the progress of the reaction was monitored by TLC. After completion of the reaction, catalyst was separated by an external magnet and washed with CH2Cl2. Then, the pure product was isolated by passing of the reaction mixture through a short column using n-hexane and ethyl acetate (9:1) as eluent.

The synthetic route of 6351-10-6 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Rostami, Amin; Tahmasbi, Bahman; Abedi, Fatemeh; Research on Chemical Intermediates; vol. 42; 4; (2016); p. 3689 – 3701;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Electric Literature of 6351-10-6, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 6351-10-6, name is 2,3-Dihydro-1H-inden-1-ol. A new synthetic method of this compound is introduced below.

General procedure: A mixture of alcohol (0.5 mmol) in the case of solids, which had been powedered for 1-2 min and halosilanes (0.55 mmol) was transferred to a 4 mL screw-capped vial, and stirred at rt or heated at 70-75 C for 0.5 h-24 h. The progress of the reaction mixture was monitored by TLC. Upon completion of the reaction, the crude reaction mixture was cooled down to the room temperature and volatile product (TMS)2O was removed by evaporation at 30-35oC under reduced pressure and the remaining was analysed by 1H NMR. Finally, if necessary, the pure final product was obtained after column chromatography on dried silica. Detailed experimental information such as isolated yields, and spectroscopic and other identification data are given in Characterization Data of Isolated Final Products chapter in the SI.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,6351-10-6, its application will become more common.

Reference:
Article; Ajvazi, Njomza; Stavber, Stojan; Tetrahedron Letters; vol. 57; 22; (2016); p. 2430 – 2433;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Electric Literature of 6351-10-6 , The common heterocyclic compound, 6351-10-6, name is 2,3-Dihydro-1H-inden-1-ol, molecular formula is C9H10O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

DMAP (143.8 mg, 1.25 mol) and acetic anhydride (1185.6 L,12.48 mmol) were added to a rac-indanol (rac-2), 500 mg,4.16 mmol) solution in dichloromethane (40 mL). The reaction wasstirred at room temperature during 4 h and after that time, thesolvent was evaporated under reduced pressure. The resultingcrude was purified by flash chromatography on silica gel (5-95%EtOAc/hexane) to afford the desired rac-indanyl acetate (rac-3) asa yellow liquid in 80% yield.

The synthetic route of 6351-10-6 has been constantly updated, and we look forward to future research findings.

Reference:
Article; De Mattos, Marcos Carlos; De Fonseca, Thiago Sousa; Da Silva, Marcos Reinaldo; De Oliveira, Maria Da Conceicao Ferreira; De Lemos, Telma Leda Gomes; De Marques, Ricardo Araujo; Applied Catalysis A: General; vol. 492; 1; (2015); p. 76 – 82;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Related Products of 6351-10-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 6351-10-6, name is 2,3-Dihydro-1H-inden-1-ol, molecular formula is C9H10O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

General procedure: To a stirring mixture of the substrate (1 mmol) and RiHA (0.08 g) in CH3CN (3 mL),HMDS (0.75 mmol, 0.120 g) was added at room temperature. The progress of the reaction was monitored by TLC. After completion of the reaction, the mixture was filtered and the residue was washed with acetonitrile (5 mL). Evaporation of the solvent gave almost pure product(s). Further purification was carried out by bulb-to-bulb distillation under reduced pressure or recrystallization to afford pure silyl ether(s).

According to the analysis of related databases, 6351-10-6, the application of this compound in the production field has become more and more popular.

Reference:
Article; Shirini; Akbari-Dadamahaleh, Somayeh; Mohammad-Khah, Ali; Phosphorus, Sulfur and Silicon and the Related Elements; vol. 189; 5; (2014); p. 577 – 586;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthetic Route of 6351-10-6 , The common heterocyclic compound, 6351-10-6, name is 2,3-Dihydro-1H-inden-1-ol, molecular formula is C9H10O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General procedure: The acetates were synthesized by classical chemical acetylations via the corresponding racemic alcohol (1 equiv), using 1.5 equiv of anhydride acetic, 1.2 equiv of Et3N, and a catalytic amount of 4-dimethylaminopyridine (0.1 equiv) in 4 ml of ether. The acetates were obtained pure after standard work-up. The 1H NMR spectra of these products were in good agreement with the literature.

The synthetic route of 6351-10-6 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Merabet-Khelassi, Mounia; Houiene, Zahia; Aribi-Zouioueche, Louisa; Riant, Olivier; Tetrahedron Asymmetry; vol. 23; 11-12; (2012); p. 828 – 833;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts