Category: 63012-03-3

《Manganese complex-catalyzed oxidation and oxidative kinetic resolution of secondary alcohols by hydrogen peroxide》 was published in Chemical Science in 2017. These research results belong to Miao, Chengxia; Li, Xiao-Xi; Lee, Yong-Min; Xia, Chungu; Wang, Yong; Nam, Wonwoo; Sun, Wei. Recommanded Product: (3-Chlorophenyl)(phenyl)methanol The article mentions the following:

The highly efficient catalytic oxidation and oxidative kinetic resolution (OKR) of secondary alcs. has been achieved using a synthetic manganese catalyst with low loading and hydrogen peroxide as an environmentally benign oxidant in the presence of a small amount of sulfuric acid as an additive. The product yields were high (up to 93%) for alc. oxidation and the enantioselectivity was excellent (>90% ee) for the OKR of secondary alcs. Mechanistic studies revealed that alc. oxidation occurs via hydrogen atom (H-atom) abstraction from an α-CH bond of the alc. substrate and a two-electron process by an electrophilic Mn-oxo species. D. functional theory calculations revealed the difference in reaction energy barriers for H-atom abstraction from the α-CH bonds of R- and S-enantiomers by a chiral high-valent manganese-oxo complex, supporting the exptl. result from the OKR of secondary alcs. In the experiment, the researchers used many compounds, for example, (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Recommanded Product: (3-Chlorophenyl)(phenyl)methanol)

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains. The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.Recommanded Product: (3-Chlorophenyl)(phenyl)methanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Recommanded Product: 63012-03-3On September 1, 2008 ,《Cesium hydroxide-promoted aerobic oxidation of sec-aromatic alcohols》 was published in Tetrahedron Letters. The article was written by Zhang, Weiwei; Liu, Miaochang; Wu, Huayue; Ding, Jinchang; Cheng, Jiang. The article contains the following contents:

A CsOH-promoted aerobic oxidation of sec-aromatic alcs. was developed, using air as a free and clean oxidant, and providing aryl ketones in good to excellent yields.(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Recommanded Product: 63012-03-3) was used in this study.

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains.Recommanded Product: 63012-03-3 The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Safety of (3-Chlorophenyl)(phenyl)methanolOn March 27, 2013, Zhang, Wenxue; Dai, Yisi; Zhu, Haizhen; Zhang, Wei published an article in Tetrahedron Letters. The article was 《One-pot synthesis of indene derivatives by CF3SO3H-promoted reactions of benzylic alcohols and 1,3-dicarbonyl compounds》. The article mentions the following:

An efficient and convenient one-pot synthesis of indene derivatives was achieved in moderate to high yields by the CF3SO3H promoted coupling/cyclization reaction of benzylic alcs. and 1,3-dicarbonyls for the first time. For the reactions of methoxy- or methyl-substituted diarylmethanols with 1,3-dicarbonyls, 2 equiv of CF3SO3H was needed to reach the best results; but for the reactions of methoxy-substituted arylethanols with 1,3-dicarbonyls, 0.6 equiv of CF3SO3H at lower temperatures was capable of promoting the reaction finished. After reading the article, we found that the author used (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Safety of (3-Chlorophenyl)(phenyl)methanol)

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains.Safety of (3-Chlorophenyl)(phenyl)methanol The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《A new preparative method for optically active diarylcarbinols》 was published in Tetrahedron: Asymmetry in 1991. These research results belong to Toda, Fumio; Tanaka, Koichis; Koshiro, Kenzo. Related Products of 63012-03-3 The article mentions the following:

Diarylcarbinols RC6H4CHPhOH (I; R = 3-Me, 4-Me, 3-Cl, 4-Cl, 3-Br, 4-Br, 3-MeO, 3-NO2, 4-NO2) were resolved by complexation with brucine. Me3CCHPhOH and Cl3CCHPhOH were resolved similarly, but ortho isomers of I were not resolved, although they also formed complexes with brucine. The experimental part of the paper was very detailed, including the reaction process of (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Related Products of 63012-03-3)

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains.Related Products of 63012-03-3 The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xing, Chun-Hui; Hu, Qiao-Sheng published an article on February 10 ,2010. The article was titled 《Ni(COD)2/4-ClC6H4COR-catalyzed addition reactions of arylboroxines with aldehydes》, and you may find the article in Tetrahedron Letters.Product Details of 63012-03-3 The information in the text is summarized as follows:

Secondary aralkyl alcs. RCH(OH)R1 (R = Ph, 4-MeC6H4, 4-MeOC6H4, 4-BrC6H4, 4-ClC6H4, 3-ClC6H4, 2-MeOC6H4, PhCH2CH2, Ph2CHCH2, Me2CHCH2, cyclohexyl; R1 = Ph, 4-MeC6H4, 4-MeOC6H4, 2-MeC6H4) are prepared in 81-96% yields by the addition of triarylboroxines (R1BO)3 to aldehydes RCHO in the presence of bis(η4-1,2,5,6-cyclooctadiene)nickel(0) and 4-chlorophenyl carbonyl compounds 4-ClC6H4COR2 (R2 = H, Me, Ph), particularly 4-chlorobenzophenone. In the experiment, the researchers used (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Product Details of 63012-03-3)

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains.Product Details of 63012-03-3 The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Copper-catalyzed synthesis of diarylamines using p-toluenesulfonamides and benzhydrol derivatives under homogeneous borrowing hydrogen conditions》 was published in Comptes Rendus Chimie in 2020. These research results belong to Ashouri, Akram; Samadi, Saadi; Ahmadian, Masoud; Nasiri, Behzad. Application of 63012-03-3 The article mentions the following:

Diarylamines ArCH(NTs)(Ph) [Ar = Ph, 4-MeC6H4, 2-ClC6H4, etc.] were synthesized using p-toluene sulfonamides with benzhydrol derivatives in the presence of a copper/bisphosphine complex by Borrowing Hydrogen (BH) mechanism. The use of readily available and cost-effective copper salts, short reaction times, high yield and reaction rates were highlighted. In the experiment, the researchers used (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Application of 63012-03-3)

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains. The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.Application of 63012-03-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2012,Advanced Synthesis & Catalysis included an article by Tian, Yu; Sui, Yi; Gu, Yonghong; Tian, Shi-Kai. Formula: C13H11ClO. The article was titled 《Expedient synthesis of functionalized triarylmethanols through tandem formation of geminal C-C and C-O bonds》. The information in the text is summarized as follows:

The rearrangement-oxidation of N,N-disubstituted anilines and the formal dehydrogenative cross-coupling of diarylmethanols with aniline derivatives were developed for the preparation of sym. and unsym. functionalized triarylmethanols. Both reactions proceed smoothly in trifluoroacetic acid in the presence of an inexpensive oxidant (MnO2 or K2S2O8) and a catalytic amount of Pd(AcO)2 to give a range of functionalized triarylmethanols in moderate to good yields and with extremely high regioselectivity. The two unprecedented reactions involve tandem formation of geminal C-C and C-O bonds, and they are synthetically useful, atom-efficient, and operationally simple. The experimental part of the paper was very detailed, including the reaction process of (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Formula: C13H11ClO)

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains. The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.Formula: C13H11ClO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Direct Electrosynthesis of Ketones from Benzylic Methylenes by Electrooxidative C-H Activation》 were Meng, Li; Su, Jihu; Zha, Zhenggen; Zhang, Li; Zhang, Zhenlei; Wang, Zhiyong. And the article was published in Chemistry – A European Journal in 2013. Electric Literature of C13H11ClO The author mentioned the following in the article:

Direct electrosynthesis of ketones R1C6H4C(O)R2 (R1 = H, 4-F, 4-AcO, 4-O2N, 3-Me, 2-Cl, etc.; R2 = Me, n-Pr, Ph, 4-MeC6H4) or α-tetralone in moderate to good yields from the corresponding benzylic methylenes R1C6H4CH2R2 or tetralin, resp., in an undivided cell is described. The method features a green oxidant of mass-free electrons, wide substrate scope and mild conditions. The reaction intermediate radical was detected by ESR spectroscopy, and the reaction mechanism was proposed.(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3Electric Literature of C13H11ClO) was used in this study.

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy-containing compounds engage in intermolecular hydrogen bonding increasing the electrostatic attraction between molecules and thus to higher boiling and melting points than found for compounds that lack this functional group.Electric Literature of C13H11ClO Organic compounds, which are often poorly soluble in water, become water-soluble when they contain two or more hydroxy groups, as illustrated by sugars and amino acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Metal-free and recyclable route to synthesize polysubstituted olefins via C-C bond construction from direct dehydrative coupling of alcohols or alkenes with alcohols catalyzed by sulfonic acid-functionalized ionic liquids》 was published in Advanced Synthesis & Catalysis in 2014. These research results belong to Han, Feng; Yang, Lei; Li, Zhen; Zhao, Yingwei; Xia, Chungu. HPLC of Formula: 63012-03-3 The article mentions the following:

A direct synthesis of polysubstituted olefins via construction of C-C bonds, which involves the direct dehydrative coupling of alcs. or alkenes with alcs., was realized using a series of alkanesulfonic acid group-functionalized ionic liquids (SO3H-functionalized ILs) without additives. The metal-free and recyclable catalyst system avoided the disposal and neutralization of acidic catalysts after reaction and tolerated a broad range of substrates, including benzylic, allyl, propargylic, aliphatic and aromatic or aliphatic olefins. Addnl., the catalytic system was suitable for a gram-scale preparation Preliminary mechanistic studies indicated that the C-H bond cleavage in this reaction might be involved in the rate-determining step. After reading the article, we found that the author used (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3HPLC of Formula: 63012-03-3)

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains. The joining of a fatty acid to glycerol to form a triacylglycerol removes the −OH from the carboxy end of the fatty acid.HPLC of Formula: 63012-03-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Yaxin; Zhao, Jianyou; Qiao, Tianjiao; Zhang, Jian; Chen, Gong published their research in Chinese Journal of Chemistry on December 31 ,2021. The article was titled 《Tunable System for Electrochemical Reduction of Ketones and Phthalimides》.COA of Formula: C13H11ClO The article contains the following contents:

An efficient, tunable system for electrochem. reduction of ketones R1C(O)R2 (R1 = Ph, pyridin-2-yl, 4-chlorophenyl, etc.; R2 = H, t-Bu, thiophen-2-yl, 3-bromophenyl, etc.) and phthalimides I (R3 = prop-2-en-1-yl, phenoxymethyl, Bn, etc.) at room temperature without the need for stoichiometric external reductants was reported. By utilizing NaN3 as the electrolyte and graphite felt as both the cathode and the anode, it was able to selectively reduce the carbonyl groups of the substrates to alcs. R1C(OH)R2, pinacols (R1C(OH)R2)2, or methylene groups e.g., 13-chloro-4-azatricyclo[9.4.0.0 (3,8)]pentadeca-1(11),3,5,7,12,14-hexaene by judiciously choosing the solvent and an acidic additive. The reaction conditions were compatible with a diverse array of functional groups, and phthalimides I could undergo one-pot reductive cyclization to afford products with indolizidine scaffolds e.g., 10-azatetracyclo[8.7.0.0(2,7).0(12,17)]heptadeca-2,4,6,12(17),13,15-hexaen-11-one. Mechanistic studies showed that the reactions involved electron, proton, and hydrogen atom transfers. Importantly, an N3/HN3 cycle operated as a hydrogen atom shuttle, which was critical for reduction of the carbonyl groups to methylene groups e.g., 13-chloro-4-azatricyclo[9.4.0.0 (3,8)]pentadeca-1(11),3,5,7,12,14-hexaene. In addition to this study using (3-Chlorophenyl)(phenyl)methanol, there are many other studies that have used (3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3COA of Formula: C13H11ClO) was used in this study.

(3-Chlorophenyl)(phenyl)methanol(cas: 63012-03-3) belongs to hydroxy-containing compounds. Hydroxy-containing compounds engage in intermolecular hydrogen bonding increasing the electrostatic attraction between molecules and thus to higher boiling and melting points than found for compounds that lack this functional group. Organic compounds, which are often poorly soluble in water, become water-soluble when they contain two or more hydroxy groups, as illustrated by sugars and amino acid.COA of Formula: C13H11ClO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts