Category: 627-18-9

《Synthesis, Molecular Docking Simulation, and Enzymatic Degradation of AB-Type Indole-Based Polyesters with Improved Thermal Propertiesã€?was published in Biomacromolecules in 2020. These research results belong to Wang, Ping; Linares-Pasten, Javier A.; Zhang, Baozhong. Related Products of 627-18-9 The article mentions the following:

We report the facile synthesis of a series of indole-based hydroxyl-carboxylate (AB-type) monomers by a one-step procedure. These monomers were successfully polymerized by melt polycondensation to yield AB-type polyesters with a varied number of flexible methylene units in the backbones. These indole-based AB-polyesters showed decent thermal stability according to the TGA results (onset thermal degradation temperature of >330°C), and their glass transition temperatures are dependent on the length of the methylene bridge (Tg â‰?62-102°C) according to the DSC results. Furthermore, DSC and WAXD measurements revealed that these polymers did not crystallize from melt, but the ones with flexible structures could crystallize from solution Mol. docking simulations showed favorable interactions between indole-based polyesters and polyethylene terephthalate hydrolase (PETase) from Ideonella sakaiensis. This was corroborated by the exptl. results, which indicated that the PETase enzyme has degrading activity on the indole-based AB polyesters except for the one with the highest degree of crystallinity. In the part of experimental materials, we found many familiar compounds, such as 3-Bromopropan-1-ol(cas: 627-18-9Related Products of 627-18-9)

3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Related Products of 627-18-9

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Enzymatic synthesis of selenium-containing amphiphilic aliphatic polycarbonate as an oxidation-responsive drug delivery vehicleã€?were Yang, Xian-Ling; Xing, Xiu; Li, Jun; Liu, Yan-Hong; Wang, Na; Yu, Xiao-Qi. And the article was published in RSC Advances in 2019. Related Products of 627-18-9 The author mentioned the following in the article:

Although functional aliphatic polycarbonates (APCs) have attracted prominent research interest as stimuli-responsive biomaterials, the majority of functional APCs are fabricated by detrimental organometallic catalysts or organo-catalysts. Herein, a facile synthetic strategy based on enzymic polymerization was developed to construct a selenium-containing amphiphilic aliphatic polycarbonate (mPEG-b-CMP45). Specifically, the selenium in its backbone framework underwent a hydrophobic-hydrophilic transition upon exposure to the abnormal ROS level of the tumor, thus providing a promising platform for ROS-triggered drug release. This amphiphilic mPEG-b-CMP45 efficiently encapsulated doxorubicin (DOX) via self-assembly in aqueous solution and showed an excellent ability to regulate the release of DOX in response to H2O2 at biol. relevant concentrations (100 μM). These DOX-loaded nanoparticles could easily be internalized into U87 cells and possess the inherent antitumor properties of DOX, while they exhibited much lower cytotoxicity in normal cells HL-7702. Moreover, in many cases, the introduction of selenium caused high cytotoxicity of the materials, but the cytotoxicity results in HL-7702 cells demonstrated the good biocompatibility of mPEG-b-CMP45. These collective data suggested the potential use of mPEG-b-CMP45 as a biocompatible and smart drug delivery vehicle. The experimental part of the paper was very detailed, including the reaction process of 3-Bromopropan-1-ol(cas: 627-18-9Related Products of 627-18-9)

3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Related Products of 627-18-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Spitzer, Lea; Lecommandoux, Sebastien; Cramail, Henri; Jerome, Francois published an article in 2021. The article was titled 《Sequential acid-catalyzed alkyl glycosylation and oligomerization of unprotected carbohydratesã€? and you may find the article in Green Chemistry.Name: 3-Bromopropan-1-ol The information in the text is summarized as follows:

An efficient method has been developed to synthesize end-functionalized oligosaccharides from unprotected monosaccharides in a one-pot/two-step approach. In the first step, mannose (and glucose) was functionalized with an alkyne group at the anomeric position through the Fisher-glycosylation reaction with propargyl alc. as a glycosyl acceptor. N the second step, the functionalized monosaccharides were oligomerized and the exptl. conditions were optimized by varying the temperature, time and the molar ratio between alc. and sugar to reach an oligosaccharide up to 8 units. The obtained oligosaccharides showed complete propargylation at their reducing chain-end and were successfully coupled to oleic acid via the Huisgen reaction, affording bio-based surfactants. The experimental part of the paper was very detailed, including the reaction process of 3-Bromopropan-1-ol(cas: 627-18-9Name: 3-Bromopropan-1-ol)

3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Name: 3-Bromopropan-1-ol

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Safety of 3-Bromopropan-1-olIn 2021 ,《A fluorescent probe for the discrimination of oxidation states of palladiumã€?appeared in Chemical Science. The author of the article were Jiang, Lijun; Mak, Ho-Nam; Walter, Edward R. H.; Wong, Wing-Tak; Wong, Ka-Leung; Long, Nicholas J.. The article conveys some information:

Palladium-based catalysts are widely used in pharmaceutical industries, which can sometimes cause palladium contamination in pharmaceutical drug manufacture It is important to sep. quantify the different oxidation states of palladium (Pd0 and Pd2+) in pharmaceuticals as they react with scavengers differently. Although palladium sensors have been under intense investigation, oxidation state differentiators are very rare. Here, we report a simple porphyrin-coumarin conjugate, PPIX-L2, that can selectively discriminate between the oxidation states of palladium. The reaction of PPIX-L2 with Pd0 showed a 24-fold fluorescence increase of the coumarin emission, meanwhile, the presence of Pd2+ led to a 98% quenching of the porphyrin emission. Fluorescent responses of PPIX-L2 towards Pd0 and Pd2+ are specific, and its sensitivity towards both palladium species is significantly increased with a detection limit of 75 nM and 382 nM for Pd0 and Pd2+ resp. The experimental part of the paper was very detailed, including the reaction process of 3-Bromopropan-1-ol(cas: 627-18-9Safety of 3-Bromopropan-1-ol)

3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Safety of 3-Bromopropan-1-ol

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The author of 《A novel phosphonic acid functional polythiophene fluorescent sensor for Ca2+ and its live cell imagingã€?were Yang, Ting; Hu, Zhiru; Liu, Jilin; Zhang, Zhiquan; Feng, Guodong. And the article was published in Analytical Methods in 2019. Category: alcohols-buliding-blocks The author mentioned the following in the article:

Calcium ions are indispensable to various physiol. activities of the body, so the detection of calcium ions is very important. In this work, a new water-soluble polythiophene derivative poly{((thiophene-3,4-diylbis(oxy))bis(propane-3,1-diyl))bis(phosphonic acid)} (PT-PHO) was designed and synthesized via oxidative polymerization with FeCl3. The polymer containing phosphonic acid groups could be used as a “”turn off”” fluorescent sensor for Ca2+ detection. Under optimal conditions, PT-PHO exhibits high selectivity and sensitivity to detect Ca2+ among metal ions. The fluorescence intensity of PT-PHO shows a linear response toward Ca2+ in the range of 0.05-50 μmol L-1 with a limit of detection (LOD) of 44 nmol L-1. In addition, PT-PHO has low toxicity and good biocompatibility. Thus, it could be used for imaging lysosomes in cells and detecting intracellular calcium ions. The experimental process involved the reaction of 3-Bromopropan-1-ol(cas: 627-18-9Category: alcohols-buliding-blocks)

3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Bio-inspired drug-dominated supramolecular nanocomplex based on low molecular weight heparin for progressive tumor therapyã€?was written by Yu, Yao; Xu, Cheng; Zhen, Le; Yang, Shan; Zhou, Jianping; Yao, Jing. Recommanded Product: 3-Bromopropan-1-olThis research focused ontumor antitumor doxorubicin heparin; (KLAKLAK)(2) peptide; Anti-angiogenesis; Low molecular weight heparin; Mitochondrial damage; Supramolecular assembly. The article conveys some information:

Low mol. weight heparin (LMWH) is a natural sulfated glycosaminoglycan with the affinity to proangiogenic factors, rendering it a promising agent for tumor therapy. Inspired by DOX binding to the helix of DNA, mitochondrial damage KLA peptide derivative (mKLA) and anti-angiogenic LMWH-chrysin conjugate (LC) are constructed to simulate the double strands for doxorubicin (DOX) binding (LKD nanocomplex). Initiated and “”locked”” by DOX, mKLA and LC temporarily aggregate by π-π stacks, electrostatic and hydrophobic interactions in aqueous condition with self-amplified DOX loading (19.07 ± 1.08 wt%). During endosome-lysosome trafficking, DOX protonated by H+ could “”unlock”” the LKD nanocomplex to disassemble, which enables mKLA and DOX to damage mitochondria and nucleus DNA resp., and LMWH could also inhibit angiogenesis. Based on the strong inhibition of tumors at all stages in vivo, we hold that LKD nanocomplex provides a new opportunity based on smart construction of carbohydrate materials for clin. advanced cancer patients. In the experiment, the researchers used many compounds, for example, 3-Bromopropan-1-ol(cas: 627-18-9Recommanded Product: 3-Bromopropan-1-ol)

3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Recommanded Product: 3-Bromopropan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Ni-Catalyzed reductive arylalkylation of unactivated alkenesã€?were Jin, Youxiang; Wang, Chuan. And the article was published in Chemical Science in 2019. Synthetic Route of C3H7BrO The author mentioned the following in the article:

In this protocol Ni-catalyzed reductive arylalkylation of unactivated alkenes tethered to aryl bromides with primary alkyl bromides was accomplished, which provided a new path to construct diverse benzene-fused carbo- and heterocyclic cores including indanes, tetrahydroisoquinolines, indolines and isochromanes I [R1 = Me, Et, i-Pr, cyclohexyl; R2 = H, Me, Et; R3 = 5-OMe, 5-F, 4-Cl, etc.; R4 = CN, OAc, F, etc.; X = CH2, NH, NMe, O; m = 0,3,4,5,6; n = 0,1]. Notably, this new method circumvented the pregeneration of organometallics and demonstrated high tolerance to a wide range of functional groups. The preliminary mechanistic investigations suggested a reaction pathway with an intermediate reduction In addition to this study using 3-Bromopropan-1-ol, there are many other studies that have used 3-Bromopropan-1-ol(cas: 627-18-9Synthetic Route of C3H7BrO) was used in this study.

3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Synthetic Route of C3H7BrO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Applied Surface Science included an article by Qu, Ke; Kondengaden, Shukkoor M.; Li, Jian; Wang, Xuewei; Sevilla, Michael D.; Li, Lei; Zeng, Xiangqun. Application of 627-18-9. The article was titled 《Carbohydrate-functionalized polythiophene biointerface: design, fabrication, characterization and application for protein analysisã€? The information in the text is summarized as follows:

In this study, a general method for fabricating glycosylated conductive polymer (CP) biointerface was demonstrated for a label-free electrochem. biosensor. A 3-(3-azidopropoxy) thiophene monomer was designed and synthesized. By electrochem. polymerizing this monomer in ionic liquid [Bmim][BF4], a unique conductive polymer was formed, allowing grafting of lactose or ferrocene via post-polymerization Cu(I)-catalyzed click reaction. X-ray photoelectron spectra validated the covalent 1, 2, 3-triazole ring formation during this click functionalization. SEM study showed an increasing of the crystallinity of the CPs after click functionalization with lactose or ferrocene. The binding of the fabricated lactosylated polythiophene biointerface with Erythrina Cristagalli lectin (ECL) was characterized with differential pulse voltammetry, showing excellent sensitivity and selectivity for ECL anal. This study illustrated a new glycosylated CP biointerface design and fabrication method that can be applied for developing real-time and label-free electrochem. biosensor to study protein-carbohydrate interactions for protein anal. In the part of experimental materials, we found many familiar compounds, such as 3-Bromopropan-1-ol(cas: 627-18-9Application of 627-18-9)

3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Application of 627-18-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Wang, Zhigang; Lan, Yingjia; Liu, Peng; Li, Xiaohong; Zhao, Youliang published an article in Polymer Chemistry. The title of the article was 《Rational design of a multi-in-one heterofunctional agent for versatile topological transformation of multisite multisegmented polystyrenesã€?Electric Literature of C3H7BrO The author mentioned the following in the article:

Architecture-transformable polymers can expand the family of stimuli-responsive polymers and be utilized to reveal the topol. effect. Despite the tremendous progress, it remains a great challenge to achieve single polymer based on-demand topol. transformations with reduced, similar and enhanced molar masses. To address this challenge, an initiating, coupling and pH/thermo-labile agent is designed to synthesize linker-reactive multisite multisegmented polymers (LMMPs) via tandem ATRP and ATRC, followed by intermol. anthracene dimerization to generate single-chain folding polystyrenes. Meanwhile, bromine and hydroxyl groups are incorporated into each linker to generate graft copolymers comprising poly(tert-Bu acrylate) and poly(ε-caprolactone) side chains. The self-immolative tertiary amine ester linker allows thermo-triggered topol. transformation from multisegmented, intrachain folding and graft polymers to one-segment polymers. The robust one-shot strategy can afford a promising platform to construct heterofunctional multisegmented polymers with tailor-made structures and functions. After reading the article, we found that the author used 3-Bromopropan-1-ol(cas: 627-18-9Electric Literature of C3H7BrO)

3-Bromopropan-1-ol(cas: 627-18-9) is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols.Electric Literature of C3H7BrO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Reddy, Sravanthi S.; Pal, Sunit; Ghosh, Sudip; Prabhakaran, Erode N. published their research in ChemBioChem in 2021. The article was titled 《Hydrogen Bond Surrogate-Constrained Dynamic Antiparallel β-Sheetsã€?Synthetic Route of C3H7BrO The article contains the following contents:

Antiparallel β-sheets are important secondary structures within proteins that equilibrate with random-coil states; however, little is known about the exact dynamics of this process. Here, the first dynamic β-sheet models that mimic this equilibrium have been designed by using an H-bond surrogate that introduces constraint and torque into a tertiary amide bond. 2D NMR data sufficiently reveal the structure, kinetics, and thermodn. of the folding process, thereby leading the way to similar anal. in isolated biol. relevant β-sheets. In the experiment, the researchers used many compounds, for example, 3-Bromopropan-1-ol(cas: 627-18-9Synthetic Route of C3H7BrO)

3-Bromopropan-1-ol(cas: 627-18-9) was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. Furthermore, it was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.Synthetic Route of C3H7BrO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts