Category: 62640-03-3

On June 8, 2006, Kim, Tae Uk; Na, Hee Seok; Kim, Duk Hee published a patent.Safety of 2-(Methylamino)ethan-1-ol hydrochloride The title of the patent was ABS resin compositions with low coefficient of linear thermal expansion. And the patent contained the following:

The thermoplastic acrylonitrile-butadiene-styrene(ABS) resin composition with low coefficient of linear thermal expansion according to the present invention comprises (A) (a1) 10-100 parts by weight of a rubber-modified grafted copolymer; and (a2) 100 parts by weight of a rubber phase grafted copolymer prepared by 0-90 parts by weight of copolymer prepared by a vinyl cyanide compound and an aromatic vinyl compound; (B) 1-30 parts by weight of vinyl copolymer containing maleic anhydride; and (C) 1-20 parts by weight of a clay mineral organized with a compound containing functional groups; wherein said compound containing functional groups is selected one or more from the compounds having an onium ion that can proceed an ion exchange reaction with said clay mineral, and having a radical-polymerizable group. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Safety of 2-(Methylamino)ethan-1-ol hydrochloride

The Article related to acrylonitrile butadiene styrene graft copolymer blend, Synthetic Elastomers and Natural Rubber: Compounding and Processing and other aspects.Safety of 2-(Methylamino)ethan-1-ol hydrochloride

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On December 21, 2006, Eliu, Victor Paul; Froehling, Beate; Kauffmann, Dominique published a patent.Computed Properties of 62640-03-3 The title of the patent was Styryl sulfide dyes, compositions thereof and processes for their preparation. And the patent contained the following:

Disclosed are styryl sulfide dyes of formula (I), wherein R1, R’1, R2, R’2, R3 and R’3 independently from each other are H; C1-C20 alkyl or C1-C20 alkoxy, which may be substituted by one or more C1-C5 alkoxy, halogen, -NH2, mono-C1-C5 alkylamino, di-C1-C5 alkylamino, -NO2 or hydroxy; C3-C6 cycloalkyl; -C(O)H; -C(O)-C1-C5 alkyl; halogen; NO2; OH; Ph, which may be substituted by one or more C1-C5 alkyl, C1-C5 alkoxy, halogen, -NH2, mono-C1-C5 alkylamino, di-C1-C5 alkylamino, -NO2 or hydroxy; or a radical of formula -NR4R5, wherein R4 and R5 independently from each other are H; C1-C12 alkyl, which may be substituted by one or more C1-C5 alkyl, C1-C5 alkoxy, hydroxy or -(CO)-H; -(CO)-C1-C5 alkyl; Ph or phenyl-C1-C4 alkyl, wherein the Ph moiety may be substituted by one or more C1-C5 alkyl, C1-C5 alkoxy, halogen, -NH2, mono-C1-C5 alkylamino, di-C1-C5 alkylamino, -NO2, carboxy or hydroxy; W1, W’1, W2, W’2, W3, W’3, W4 or W’4, independently from each other are -CH- or -N+-; wherein only one of W1/W’1, W2/W’2, W3/W’3, W4/W4′ is -N+; and the bivalent radical -Q-Z-Y-S-S-Y’-Z’-Q’- is bonded to W1 or W2 and W’1 or W’2 resp.; Y1 and Y2 independently from each other are C1-C10 alkylene; C5-C10 cycloalkylene; C5-C12 arylene; or C5-C12 arylene-(C1-C10 alkylene); Q and Q’ independently from each other are the direct bond; or -C(O)-; -C(O)O-; -OCO-; -N(R6)-; -N+(R6)(R7)-; -C(O)N(R6)-; -(R6)NC(O)-; -O-; -S-; -S(O)-; or -S(O)2-; and R6 and R7 independently from each other are H. Further, the present invention relates to novel styryl sulfide compounds, compositions thereof, especially comprising other dyes, and to processes for their preparation The novel styryl sulfide dyes are useful for the dyeing of organic materials, such as keratin fibers, wool, leather, silk, cellulose or polyamides, especially keratin-containing fibers, cotton or nylon, and human hair. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Computed Properties of 62640-03-3

The Article related to styryl sulfide dye composition process preparation, Dyes, Organic Pigments, Fluorescent Brighteners, and Photographic Sensitizers: Heterocyclics and other aspects.Computed Properties of 62640-03-3

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Alcohol – Wikipedia,
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On January 12, 2011, Yu, Shishan; Chen, Xiaoguang; Xu, Song; Qu, Jing; Zhou, Qing; Ma, Shuanggang published a patent.Formula: C3H10ClNO The title of the patent was Cassaine alkaloid analogs, their preparation method, and medical application. And the patent contained the following:

The invention disclosed a kind of Cassaine alkaloid analogs, preparation method, and medical application as antitumor agents. The claimed Cassaine alkaloid analogs are shown in structure I and II (R1, R2 = H, (un)substituted C1-C6 alkyl, Ph, -NR1R2 forming 5-member, 6-member or 7-member heterocycle containing 1-3 heteroatoms; R = H, (un)substituted C1-C6 alkyl). The claimed compounds are prepared from III and R1NHR2 amine via amidation (detail procedure given). The obtained compound and pharmaceutical acceptable salts , hydrates, esters, etc., can be used as antitumor agents for preventing and/or treating cancer. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Formula: C3H10ClNO

The Article related to cassaine alkaloid analog synthesis amidation antitumor agent, Terpenes and Terpenoids: Diterpenes (C20), Including Gibberellins, Retinoids, Quassinoids, and Tocopherols and other aspects.Formula: C3H10ClNO

Referemce:
Alcohol – Wikipedia,
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On December 12, 1996, Hulin, Bernard; Hoover, Dennis J.; Treadway, Judith L.; Martin, William H. published a patent.Recommanded Product: 62640-03-3 The title of the patent was Preparation of substituted indole-2-carboxamides and derivatives as glycogen phosphorylase inhibitors.. And the patent contained the following:

Title compounds [I; dotted line = optional double bond; A = CH, CR20, CH2, CHR21; ; R20 = alkyl, halo; R21 = alkyl; R1, R10, R11 = H, halo, NO2, cyano, alkyl, alkoxy, CH2F, CHF2, CF3; R2 = H, R3 = H, alkyl; R4 = H, Me, Et, Pr, hydroxyalkyl, alkoxyalkyl, (substituted) phenylalkyl, phenylhydroxyalkyl, thienylalkyl, furylalkyl, pyridylalkyl, thiazolylalkyl, triazinylalkyl, etc.; R5 = H, OH, F, alkyl, alkoxy, alkanoyl, amionoalkoxy, carboxyalkoxy, etc.; R6 = CO2H, alkoxycarbonyl, CONR8R9, COR12; R8 = H, alkyl, OH, alkoxy; R9 = H, (substituted) alkyl, OH, alkoxy, methylene-perfluorinated alkyl, Ph, pyridyl, thienyl, furyl pyrrolyl, pyrrolidinyl, oxazolyl, thiazolyl, pyranyl, piperidinyl, morpholinyl, pyridazinyl, pyrimidinyl, pyrazinyl, etc.; R12 = piperazin-1-yl, 4-alkylpiperazin-1-yl, thiomorpholino, substituted oxazetidin-2-yl, etc.], were prepared as glycogen phosphorylase inhibitors (no data). Thus, iso-Pr (3S)-amino-4-phenyl-(2R)-hydroxybutyrate, 5-chloroindole-2-carboxylic acid, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide, and 1-hydroxybenzotriazole were stirred 18 h in CH2Cl2 to give 91% iso-Pr (3S)-[(5-chloro-1H-indole-2-carbonyl)amino]-(2R)-hydroxy-4-phenylbutyrate. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Recommanded Product: 62640-03-3

The Article related to indolecarboxamide substituted preparation glycogen phosphorylase inhibitor, cardiovascular agent indolecarboxamide substituted, diabetes treatment indolecarboxamide substituted and other aspects.Recommanded Product: 62640-03-3

Referemce:
Alcohol – Wikipedia,
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On March 1, 2012, Bartolozzi, Alessandra; Bosanac, Todd; Chen, Zhidong; De Lombaert, Stephane; Dines, Jonathon Alan; Huber, John D.; Liu, Weimin; Lo, Ho Yin; Loke, Pui Leng; Morwick, Tina Marie; Nemoto, Peter Allen; Olague, Alan; Riether, Doris; Tye, Heather; Wu, Lifen; Zindell, Renee M. published a patent.Related Products of 62640-03-3 The title of the patent was Preparation of oxadiazole inhibitors of leukotriene production. And the patent contained the following:

The present invention relates to compound I [R1 and R2 together with the carbon atom to which they are attached form (un)substituted carbocyclic ring or 5-11 membered heterocyclic ring; R3 = (un)substituted 5-11 membered heteroaryl containing 1-3 heteroatoms selected from N, O and S; R4 = H, halo, alkyl, nitrile; R5 = (un)substituted alkyl, cycloalkyl, 5-11 membered heterocyclyl, etc.] and pharmaceutically acceptable salt thereof. Over three-hundred compounds I were prepared E.g., a multi-step synthesis of II, starting from the nitrile III and 1,3-dibromopropane, was described. Representative compounds I showed activity in the FLAP binding assay and in the human whole blood LTB4 production inhibition assay (IC50 values were given). The invention also relates to pharmaceutical compositions comprising compounds I, methods of using I in the treatment of various diseases and disorders, processes for preparing I and intermediates useful in these processes. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Related Products of 62640-03-3

The Article related to oxadiazole preparation leukotriene ltb4 production flap inhibitor antitumor antiinflammatory, cardiovascular allergy pulmonary renal disease fibrosis treatment oxadiazole preparation and other aspects.Related Products of 62640-03-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On January 22, 2020, De Francesco, Raffaele; Donnici, Lorena; Guidotti, Luca; Iannacone, Matteo; Di Fabio, Romano; Summa, Vincenzo; Bencheva, Leda Ivanova; De Matteo, Marilenia; Ferrante, Luca; Prandi, Adolfo; Randazzo, Pietro published a patent.Related Products of 62640-03-3 The title of the patent was Preparation of arylaminocarbonyl bicyclic sulfonamides as inhibitors of hepatitis B virus. And the patent contained the following:

The invention relates to preparation of arylaminocarbonyl bicyclic sulfonamides (I) that are inhibitors of hepatitis B virus (HBV). Compounds I wherein B is a 6-membered aryl optionally containing one or more N atoms; X is N (un)substituted with R4, or is O; Y is a single bond, a double bond, C1-4 alkanediyl, etc.; Z is C(O) or CR2R3; R1 is H, OH, etc.; R2 is H, DNH2, etc.; R3 is absent, H, D, etc.; R4 is H, OH, C1-4 alkyl; R5 is C1-3 alkyl (un)substituted with OH; R6 is C1-4 alkyl; etc., are claimed. The example compound II was prepared from an intermediate(also prepared) and formaldehyde (procedure given). The compounds of the invention were evaluated for their biol. activity (data given). Compounds I are useful alone or in combination with other agents for treating, ameliorating, preventing or curing HBV infection and related conditions. The invention also relates to pharmaceutical compositions containing I. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Related Products of 62640-03-3

The Article related to arylaminocarbonyl bicyclic sulfonamide preparation antiviral hepatitis b combination therapy, hbv infection prophylaxis combination treatment arylaminocarbonyl bicyclic sulfonamide preparation and other aspects.Related Products of 62640-03-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On January 23, 2020, De Francesco, Raffaele; Donnici, Lorena; Guidotti, Luca; Iannacone, Matteo; Di Fabio, Romano; Summa, Vincenzo; Bencheva, Leda Ivanova; De Matteo, Marilenia; Ferrante, Luca; Prandi, Adolfo; Randazzo, Pietro published a patent.Electric Literature of 62640-03-3 The title of the patent was Preparation of arylaminocarbonyl bicyclic sulfonamides as inhibitors of hepatitis B virus. And the patent contained the following:

The invention relates to preparation of arylaminocarbonyl bicyclic sulfonamides (I) that are inhibitors of hepatitis B virus (HBV). Compounds I wherein B is a 6-membered aryl optionally containing one or more N atoms; X is N (un)substituted with R4, or is O; Y is a single bond, a double bond, C1-4 alkanediyl, etc.; Z is C(O) or CR2R3; R1 is H, OH, etc.; R2 is H, DNH2, etc.; R3 is absent, H, D, etc.; R4 is H, OH, C1-4 alkyl; R5 is C1-3 alkyl (un)substituted with OH; R6 is C1-4 alkyl; etc., are claimed. The example compound II was prepared from an intermediate (also prepared) and formaldehyde (procedure given). The compounds of the invention were evaluated for their biol. activity (data given). Compounds I are useful alone or in combination with other agents for treating, ameliorating, preventing or curing HBV infection and related conditions. The invention also relates to pharmaceutical compositions containing I. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Electric Literature of 62640-03-3

The Article related to arylaminocarbonyl bicyclic sulfonamide preparation antiviral hepatitis b combination therapy, hbv infection prophylaxis combination treatment arylaminocarbonyl bicyclic sulfonamide preparation and other aspects.Electric Literature of 62640-03-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On May 12, 2022, Lee, Yoon-Suk; Kim, Kyung-Sun; Kim, Jeong-Ah; Moon, An-Na; Song, Dong-Keun; Jung, Ju-Young published a patent.Computed Properties of 62640-03-3 The title of the patent was Preparation of benzenesulfonamides linked to a fused heteroaryl as nitrogen oxide-donating PDE-5 and/or PDE-6 inhibitors. And the patent contained the following:

The title compounds I [X1 and X2 = (independently) N and C, and at least one of X1 and X2 = N; R1 = H, (un)substituted alkyl; R2 =(un)substituted alkyl; R3 = (un)substituted alkoxy; R4 = H or (un)substituted alkyl, and R5 = (un)substituted 4-membered carbocycle or heterocycle; or R4 and R5 together with the nitrogen atom to which they are attached are cyclically linked to form (un)substituted 4-membered heterocycle] or pharmaceutically acceptable salts, solvates, hydrates, prodrugs, or stereoisomers thereof, useful for treating a variety of eye diseases, were prepared For example, reacting 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonyl chloride with azetidin-3-ol hydrochloride afforded 92% II. Said compounds I are nitrogen oxide (NO) donating PDE-5 and/or -6 inhibitor compounds that include a nitrogen oxide-containing donor substituent attached to a benzenesulfonamide group. The compounds I can provide dual functionality for increasing protein kinase G (PKG) activity by inhibiting PDE-5 and PDE-6, and/or stimulating guanylate cyclase via donation of NO from the donor substituent of the compound (data given for representative compounds I). The present disclosure also provides methods of using said compounds I and compositions for inhibiting PDE-5 and/or -6 and increasing activity of PKG. Compounds I may be used as a therapeutic agent for glaucoma, age-related macular degeneration, diabetic retinopathy, xerophthalmia, dry eye syndrome, cataracts or uveitis. Ophthalmic composition comprising the compound I was disclosed. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Computed Properties of 62640-03-3

The Article related to benzenesulfonamide fused heteroaryl preparation nitrogen oxide donating pde5 pde6, eye disease glaucoma diabetic retinopathy benzenesulfonamide fused heteroaryl preparation, age related macular degeneration amd benzenesulfonamide fused heteroaryl preparation and other aspects.Computed Properties of 62640-03-3

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Alcohol – Wikipedia,
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