Application of 622-93-5, Adding some certain compound to certain chemical reactions, such as: 622-93-5, name is 3-(Diethylamino)propan-1-ol,molecular formula is C7H17NO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 622-93-5.
Reference Example 14 3-(Diethylamino)propyl 2-{(3R)-3-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-3-(2-chlorobenzyl)-4-oxo-4,5-dihydro-3H-imidazo[4,5-c]pyridine-6-carboxylate [Show Image] A solution of the compound of Reference Example 17 (100 mg), 3-diethylamino-1-propanol (45 muL), 1-hydroxybenzotriazole (40 mg), 1-ethyl-3-(dimethylaminopropyl)carbo-diimide hydrochloride (50 mg) and triethylamine (84 muL) in N,N-dimethylformamide (2 mL) was stirred at 25C for 16 hours. Water was added to the reaction mixture, followed by extraction with ethyl acetate. The organic layer was washed with water and a saturated aqueous sodium chloride solution, dried over magnesium sulfate and then filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by a silica gel column chromatography (developing solvent: chloroform/methanol = 20/1) to obtain the title compound (27 mg) as a white amorphous substance. MS (ESI+) 615 (M++1, 100%).
According to the analysis of related databases, 622-93-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Dainippon Sumitomo Pharma Co., Ltd.; EP1690863; (2006); A1;,
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