Category: 620-92-8

Synthesis of ultraviolet curable bisphenol-based epoxy acrylates and comparative study on its physico-chemical properties was written by D. Desai, Prashil;N. Jagtap, Ramandand. And the article was included in Journal of Applied Polymer Science in 2022.Electric Literature of C13H12O2 The following contents are mentioned in the article:

Photocuring resins have emerged as cutting-edge technol. in coatings, adhesives, composites, additive manufacturing, and so forth. In the present work, different bisphenol, namely A, F, and S, were used to synthesize low mol. weight epoxy resin, which was further reacted with acrylic acid monomer to form bisphenol-based epoxy acrylate (BEA). The BEA resins were formulated using reactive diluents, trimethylolpropane triacrylate, and hexanediol diacrylate in the ratio of 0-40 wt% at the increment of 10 wt% alongside a fixed quantity photoinitiator. These resins were then cast into dumbbell-shaped specimens by irradiating them under UV light. The structural elucidation of BEA resins was performed using Fourier transform IR, NMR, and UV-Vis spectroscopy. The formulated resins were also studied for their rheol. properties. Further, the UV cured specimens were evaluated for mech., thermal, contact angle, and extent of curing. These outcomes were utilized for establishing the structure-property relationship based on the functionality, reactivity, and mol. structure of synthesized BEA resins, which controllers the design architecture and crosslinking d. of UV-cured specimens. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Electric Literature of C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Electric Literature of C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bisphenol A and its analogues in paired urine and house dust from South China and implications for children’s exposure was written by Yang, Yan;Shi, Yumeng;Chen, Da;Chen, Haojia;Liu, Xiaotu. And the article was included in Chemosphere in 2022.Application of 620-92-8 The following contents are mentioned in the article:

Following the restriction of bisphenol A (BPA) in certain products, a number of bisphenol analogs (BPs) have been used as BPA replacements in different applications, raising environmental and health concerns. The present study determined a total of 13 bisphenol analogs in house dust and children urine from South China families (n = 46). Among all BPs, BPA, bisphenol S (BPS) and bisphenol F (BPF) were frequently detected in house dust, with concentrations ranging from 0.54 to 26.2μg/g (median: 2.60μg/g), 0.07-11.5μg/g (median: 0.32μg/g) and 0.02-2.4μg/g (median: 0.29μg/g), resp. BPA (median: 2.43 ng/mL) was also the dominant BP in children urine samples, accounting for 75.2 ± 27.4% of the total concentrations of urinary BPs, followed by BPS (0.23 ng/mL), whereas BPF was only detected in less than 30% of urine samples. Children’s daily intake of bisphenols through dust ingestion and total daily intakes were estimated based on the dust and urine concentrations, resp. The estimated intake of BPA, BPS and BPF via house dust ingestion accounted for 9%, 12% and 38% of the total intakes predicted based on urinary concentrations, resp., and exhibited very low exposure risks. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Application of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Application of 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Evaluation of estrogenic and antiestrogenic activity in sludge and explanation of individual compound contributions was written by Cerna, Tereza;Ezechias, Martin;Semerad, Jaroslav;Grasserova, Alena;Cajthaml, Tomas. And the article was included in Journal of Hazardous Materials in 2022.Recommanded Product: 4,4′-Methylenediphenol The following contents are mentioned in the article:

Mixture toxicity, including agonistic and antagonistic effects, is an unrevealed environmental problem. Estrogenic endocrine disruptors are known to cause adverse effects for aquatic biota, but causative chems. and their contributions to the total activity in sewage sludge remain unknown. Therefore, advanced anal. methods, a yeast bioassay and mixture toxicity models were concurrently applied for the characterization of 8 selected sludges with delectable estrogenic activity (and 3 sludges with no activity as blanks) out of 25 samples from wastewater treatment plants (WWTPs). The first applied full logistic model adequately explained total activity by considering the concentrations of the monitored compounds The results showed that the activity was primarily caused by natural estrogens in municipal WWTP sludge. Nevertheless, activity in a sample originating from a car-wash facility was dominantly caused by partial agonists – nonylphenols – and only a model enabling prediction of all dose-response curve parameters of the final mixture curve explained these results. Antiestrogenic effects were negligible, and effect-directed anal. identified the causative chems. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Recommanded Product: 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Recommanded Product: 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Assessing the toxicity of bisphenol A and its six alternatives on zebrafish embryo/larvae was written by Gao, Yue;Li, Aijing;Zhang, Wenjuan;Pang, Shaochen;Liang, Yong;Song, Maoyong. And the article was included in Aquatic Toxicology in 2022.Safety of 4,4′-Methylenediphenol The following contents are mentioned in the article:

Bisphenol A (BPA) analogs are gradually replacing BPA in the plastics industry. Whether these alternatives are indeed safer than BPA itself, however, remains unclear. Here, we studied the toxicity of BPA and six of its alternatives-BPB, BPC, BPE, BPF, BPAF, and BPAP-using zebrafish embryos/larvae. According to their half lethal concentration (LC50) values, the acute toxicity of BPA and six alternative bisphenols to zebrafish embryos, from highest to lowest, was BPAP ≈ BPAF > BPC > BPB > BPA > BPE > BPF. Under nonlethal concentrations, the tested bisphenols had different toxic effects on development in terms of reducing the hatching rate, frequency of spontaneous movements, and heart rate in the embryo, as well as inducing yolk sac edema, pericardial edema, and spinal deformation in the larvae. The estrogenic activity of BPE, BPF, and BPAF was higher than that of BPA, as shown by vtg1 expression assays. Moreover, BPA and its alternatives increased SOD activity and cell apoptosis in embryos/larvae under nonlethal concentrations Our findings indicate that BPA alternatives may not be safer than BPA in zebrafish, and that these BPA alternatives should be applied with caution. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Safety of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Safety of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effects of BPA, BPS, and BPF on Oxidative Stress and Antioxidant Enzyme Expression in Bovine Oocytes and Spermatozoa was written by Nguyen, Mimi;Sabry, Reem;Davis, Ola S.;Favetta, Laura A.. And the article was included in Genes in 2022.Formula: C13H12O2 The following contents are mentioned in the article:

Bisphenol A (BPA) and its analogs, bisphenol S (BPS) and bisphenol F (BPF), might impact fertility by altering oxidative stress pathways. Here, we hypothesize that bisphenols-induced oxidative stress is responsible for decreased gamete quality. In both female (cumulus-oocyte-complexes-COCs) and male (spermatozoa), oxidative stress was measured by CM-H2DCFDA assay and key ROS scavengers (SOD1, SOD2, GPX1, GPX4, CAT) were quantified at the mRNA and protein levels using qPCR and Western blot (COCs)/immunofluorescence (sperm). Either gamete was treated in five groups: control, vehicle, and 0.05 mg/mL of BPA, BPS, or BPF. Our results show elevated ROS in BPA-treated COCs but decreased production in BPS- and BPF-treated spermatozoa. Addnl., both mRNA and protein expression of SOD2, GPX1, and GPX4 were decreased in BPA-treated COCs (p < 0.05). In sperm, motility (p < 0.03), but not morphol., was significantly altered by bisphenols. SOD1 mRNA expression was significantly increased, while GPX4 was significantly reduced. These results support BPA’s ability to alter oxidative stress in oocytes and, to a lesser extent, in sperm. However, BPS and BPF likely act through different mechanisms. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Monitoring of Pollutants Content in Bottled and Tap Drinking Water in Italy was written by Russo, Giacomo;Laneri, Sonia;Di Lorenzo, Ritamaria;Neri, Ilaria;Dini, Irene;Ciampaglia, Roberto;Grumetto, Lucia. And the article was included in Molecules in 2022.Electric Literature of C13H12O2 The following contents are mentioned in the article:

The concentration levels of thirteen organic pollutants and selected heavy metals were investigated in 40 plastics bottled and tap water samples. Some of the selected contaminants have an ascertained or suspected endocrine disrupting activity, such as Bisphenol A (BPA) and its analogs, and Bis 2-ethylhexyl phthalate (DEHP), which are used by industries as plasticizers. The most frequently detected pollutants were Bisphenol AF (BPAF) (detection frequency (DF) = 67.5%, mean 387.21 ng L^-1), DEHP (DF = 62.5%, mean 46.19μg L^-1) and BPA (DF = 60.0%, mean 458.57 ng L^-1), with higher concentration levels found in tap waters. Furthermore, a possible level of exposure to thirteen pollutants via drinking water intake was calculated Our findings show that, even though the occurrence of contaminants and heavy metals in drinking waters does not pose an immediate, acute health risk for the population, their levels should be constantly monitored and ‘hard-wired’ into everyday practice. Indeed, the health impact to the continuous and simultaneous intake of a huge variety of xenobiotics from various sources by humans is complex and still not fully understood. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Electric Literature of C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Electric Literature of C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bisphenol A, S or F mother’s dermal impregnation impairs offspring immune responses in a dose and sex-specific manner in mice was written by Malaise, Yann;Lencina, Corinne;Cartier, Christel;Olier, Maiwenn;Menard, Sandrine;Guzylack-Piriou, Laurence. And the article was included in Scientific Reports in 2021.HPLC of Formula: 620-92-8 The following contents are mentioned in the article:

Bisphenol (BP)A is an endocrine disruptor (ED) widely used in thermal papers. Regulatory restrictions have been established to prevent risks for human health, leading to BPA substitution by structural analogs, like BPS and BPF. We previously demonstrated that oral perinatal exposure to BPA had long-term consequences on immune responses later in life. It appears now essential to enhance our understanding on immune impact of different routes of BP exposure. In this study, we aimed at comparing the impact of mother dermal exposure to BPs on offspring immune system at adulthood. Gravid mice were dermally exposed to BPA, BPS or BPF at 5 or 50μg/kg of body weight (BW)/day (d) from gestation day 15 to weaning of pups at post-natal day (PND)21. In offspring, BPs dermal impregnation of mothers led to adverse effects on immune response at intestinal and systemic levels that was dependent on the BP, the dose and offspring sex. These findings provide, for the first time, results on long-term consequences of dermal perinatal BPs exposure on immune responses in offspring. This work warns that it is mandatory to consider immune markers, dose exposure as well as sex in risk assessment associated with new BPA’s alternatives. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8HPLC of Formula: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.HPLC of Formula: 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Toxicity and behavioral response of zebrafish exposed to combined microplastic and bisphenol analogues was written by Mu, Xiyan;Qi, Suzhen;Liu, Jia;Yuan, Lilai;Huang, Ying;Xue, Jiaying;Qian, Le;Wang, Chengju;Li, Yingren. And the article was included in Environmental Chemistry Letters in 2022.Application In Synthesis of 4,4′-Methylenediphenol The following contents are mentioned in the article:

Microplastics and bisphenol analogs are emerging environmental pollutants widely occurring in freshwaters. Harmful effects of microplastics and bisphenols have been studied individually, yet there is few knowledge on their combined effect. Here, we conducted acute toxicity tests using embryonic and larval zebrafish to assess the combined lethality after co-exposure of bisphenol A or F and 0.5- and 25-μm polystyrene microplastic particles. We monitored the accumulation of microplastics in zebrafish. We also studied the impact on the behavior of larval zebrafish. Results show that co-exposure of bisphenols and polystyrene microplastics increased lethality of larvae by 6.8-51% for bisphenol F and by 6.7-30.1% for bisphenol A. However, the bisphenol lethality toward embryos remains unchanged in the presence of microplastics. Fluorescence anal. shows that 0.5- and 25-μm microplastics accumulate in the larvae gastrointestinal area in a dose-dependent pattern, but did not concentrate in the embryo. Overall, co-exposure of polystyrene microplastics and bisphenol analogs displayed stronger behavioral effects, e.g. reduced moving distance and activity, toward zebrafish larvae, compared with single pollutant exposure. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Application In Synthesis of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effective stabilization of atomic hydrogen by Pd nanoparticles for rapid hexavalent chromium reduction and synchronous bisphenol A oxidation during the photoelectrocatalytic process was written by Li, Shanpeng;Liu, Chunlei;Liu, Haijin;Lv, Wenying;Liu, Guoguang. And the article was included in Journal of Hazardous Materials in 2022.HPLC of Formula: 620-92-8 The following contents are mentioned in the article:

Atomic hydrogen (H*) plays a vital role in the synchronous redox of metallic ions and organic mols. However, H* is extremely unstable as it is easily converted to hydrogen. Herein, we designed a novel strategy for the effective stabilization of H* to enhance its utility. The synthesized Pd nanoparticles grown on the defective MoS₂ (DMS) of TiO₂ nanowire arrays (TNA) (TNA/DMS/Pd) photocathode exhibited rapid Cr(VI) reduction (∼95% in 10 min) and bisphenol A (BPA) oxidation (∼97% in 30 min), with the kinetic constants almost 24- and 6-fold higher than those of the TNA photocathode, resp. This superior performances could be attributed to: (i) the generated interface heterojunctions between TNA and DMS boosted the separation efficiencies of photogenerated electrons, thereby supplying abundant valance electrons to lower the overpotential to create a suitable microenvironment for H* generation; (ii) the stabilization of H* by Pd nanoparticles resulted in a significant increase in the yield of hydroxyl radical (^•OH). This research provides a new strategy for the effective utilization of H* toward rapid reduction of heavy metals and synchronous oxidation of the refractory organics This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8HPLC of Formula: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Enhanced degradation of bisphenol F in a porphyrin-MOF based visible-light system under high salinity conditions was written by Wang, Zhiwei;Li, Qian;Su, Ruidian;Lv, Guochun;Wang, Zhining;Gao, Baoyu;Zhou, Weizhi. And the article was included in Chemical Engineering Journal (Amsterdam, Netherlands) in 2022.COA of Formula: C13H12O2 The following contents are mentioned in the article:

The efficient degradation of organic contaminants in practical water treatment is a challenge for advanced oxidation processes via such as semiconductor photocatalysis due to interference from the inhibiting influence due to the reactions between radicals and coexisting anions in the actual water column. Herein, a porphyrinic zirconium metal-organic framework (PCN-223) is used in a visible light system to effectively decompose bisphenol F (BPF) in saline water. The PCN-223/visible-light system can effectively resist the influence of environmental coexisting anions and natural organic matter (NOM), thus demonstrating excellent performance in decomposing pollutants. Furthermore, the catalytic system is able to maintain stable contaminant degradation over a wide pH range and in five water matrixes. Coexisting anions promote the conductivity of electrons by forming ionic bonds with Zr, which enhances light-induced electron transfer under visible light. This work illustrates the mechanism and conditions under which porphyrin-MOF can resist high salt environments in photocatalysis, and provides a new perspective on the practical application of photocatalysis to overcome complex environmental disturbances. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8COA of Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.COA of Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts