Category: 620-92-8

Diaporthe/Phomopsis longicolla degrades an array of bisphenol analogues with secreted laccase was written by Baluyot, Jobriell C.;Santos, Hanna Keith;Batoctoy, Dessa Camille R.;Torreno, Vicenzo Paolo M.;Ghimire, Leela B.;Joson, Santiago Emil A. IV;Obusan, Marie Christine M.;Yu, Eizadora T.;Bela-ong, Dennis B.;Gerona, Roy R.;Velarde, Michael C.. And the article was included in Microbiological Research in 2022.Quality Control of 4,4′-Methylenediphenol The following contents are mentioned in the article:

With recent initiatives to ban bisphenol A (BPA) in certain com. products, manufacturers shifted to the production and use of BPA analogs. However, some of these BPA alternatives still possess endocrine disruptive activities. Many fungal enzymes are known to biodegrade phenolic compounds, such as BPA. However, the activity of these enzymes on BPA analogs remains unexplored. This study reports a secreted laccase from the endophytic fungus Diaporthe longicolla capable of degrading an impressive range of bisphenol analogs. The secreted crude enzymes are optimally active at pH 5 from 39°C to 60°C, efficiently degrading BPA as well as BPA analogs BPB, BPC, BPE and BPF. A purified form of laccase was identified from the crude fungal extract using FPLC and peptide sequencing. Furthermore, BPA induced the expression of this D. longicolla laccase gene. Overall, this paper demonstrated that the crude laccase enzyme from D. longicolla metabolizes BPA and select analogs, implicating the potential role of this fungus to remove environmental bisphenols. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Quality Control of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of 4,4′-Methylenediphenol

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Analysis of alkylphenols, bisphenols and alkylphenol ethoxylates in microbial-fermented functional beverages and bottled water: Optimization of a dispersive liquid-liquid microextraction protocol based on natural hydrophobic deep eutectic solvents was written by Baute-Perez, David;Santana-Mayor, Alvaro;Herrera-Herrera, Antonio V.;Socas-Rodriguez, Barbara;Rodriguez-Delgado, Miguel Angel. And the article was included in Food Chemistry in 2022.Electric Literature of C13H12O2 The following contents are mentioned in the article:

In this work, the anal. of alkylphenols, bisphenols and alkylphenol ethoxylates in bottled waters, kombuchas and water kefir was performed through a vortex-assisted dispersive liquid-liquid microextraction method based on a natural hydrophobic eutectic solvent. For this purpose, mixtures of monoterpenes and fatty acids were employed. Different factors affecting extraction were optimized and the method was validated in terms of matrix effect, linearity, limits of detection and recovery. Recovery values varied between 70.0 and 124.3% (except for 4-tert-butylphenol: 67.0% and 4-n-nonylphenol: 60.8% in water kefir) and limits of detection were in the range 0.10 ng/L – 2.99μg/L. Finally, 8 bottled waters, 8 kombuchas and 4 water kefirs were analyzed and 4-tert-octylphenol monoethoxylate was detected in water (20.28 ± 0.99 – 62.08 ± 3.63μg/L). This is the first application analyzing xenobiotic contaminants in kombucha and water kefir and the first time in which the three types of compounds are simultaneously extracted by dispersive liquid-liquid microextraction This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Electric Literature of C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Electric Literature of C13H12O2

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Tailoring diameters of carbon nanofibers with optimal mesopores to remarkably promote hemin adsorption toward ultrasensitive detection of bisphenol A was written by Zhang, Yuhuan;Chen, Yue;Lei, Yanan;Lu, Hao;Wang, Xingyu;Zhang, Zhong;Li, Jianke. And the article was included in Food Chemistry in 2022.SDS of cas: 620-92-8 The following contents are mentioned in the article:

Bisphenol A (BPA) is a worldwide used endocrine disrupting chem. that can migration from food containers and packaging, resulting in bioaccumulation of BPA in humans and causing adverse health effects. Porous electrodes have been proved with large surface areas and high sensing abilities in electrochem. detection of BPA. However, how to tailor the pore sizes to further improve the sensing performance is still a great challenge. Here, we delicately tailored the diameters of carbon nanofibers (CNFs) by adjusting electrospinning parameters to have optimal mesopore structure for strong adsorption of hemin that has been demonstrated with high electrocatalytic activity for BPA sensing. Benefiting from the optimal mesopores structure of CNFs and the synergistic effect of hemin and CNFs, this hemin@CNFs based sensor achieves an ultrahigh sensitivity of 40.97μA cm-2μM-1, a low detection limit of 3.1 nM and satisfactory recoveries from 90.2% to 104.2% in the direct detection of BPA in liquors. This work offers a promising sensing platform for ultrasensitive monitoring of BPA. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8SDS of cas: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.SDS of cas: 620-92-8

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Alcohol – Wikipedia,
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Capillary electrophoresis-mass spectrometry analysis of bisphenol A and its analogues in bottled tea beverages with dynamic pH focusing was written by Yahaya, Noorfatimah;Huang, Zi-ao;Yan, Binjun;Chen, David D. Y.. And the article was included in Food Chemistry in 2022.Recommanded Product: 620-92-8 The following contents are mentioned in the article:

A simple and sensitive method for the determination of bisphenol A and its analogs at the ng/mL level in bottled tea beverages is presented. This method utilized a dynamic pH junction to focus the analyte into a more concentrated zone, based on the electrophoretic mobility difference of analytes in the sample matrix and background electrolytes in capillary electrophoresis coupled to mass spectrometry (CE-MS). The optimized analyte focusing led to enhanced signal detection with average peak heights for five bisphenols of 53-170 folds higher than conventional injections. Under optimized conditions, the method showed good linearity in the range of 0.1-100 ng/mL, excellent limits of detection (0.03-0.04 ng/mL), good analyte recovery (80.3-118.1%) with acceptable relative standard deviations (<12%). The limits of quantifications were below the maximum permissible content of bisphenol A set by the European Commission for this product. This method was used to quant. analyze bisphenols in six different kinds of bottled tea beverages, making it a promising tool for practical applications. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Recommanded Product: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lewis Acid-Promoted Typical Friedel-Crafts Reactions Using DMSO as a Carbon Source was written by Vodnala, Nagaraju;Singh, Sanjay;Hazra, Chinmoy Kumar. And the article was included in Journal of Organic Chemistry in 2022.Quality Control of 4,4′-Methylenediphenol The following contents are mentioned in the article:

A mild and efficient synthetic protocol for the synthesis of sym. and unsym. diarylmethanes (DAMs) R¹CH₂R² (R¹ = 4-methoxyphenyl, 2,4,6-trimethylphenyl, 1H-indol-3-yl, 4-hydroxy-2-oxo-2H-chromen-3-yl, etc.; R² = 4-hydroxy-3,5-dimethylphenyl, 5-methylfuran-2-yl, 4-amino-3,5-bis(propan-2-yl)phenyl, etc.) was reported. Using DMSO as the C₁ source and TMSOTf as the Lewis acid promoter, a series of functionalized sym. and unsym. DAMs was synthesized in high yields. Gratifyingly, DMSO plays a dual role as a solvent and a C₁ source and can also be replaced with its deuterated counterpart, DMSO-d₆, enabling the incorporation of the -CD₂ moiety into the diarylmethane skeleton. The developed approach has been applied to a wide range of substrates having various functional groups, and this protocol has also been extended to the synthesis of an anti-breast cancer agent and an anticoagulant agent using common feedstock compounds In addition, the postulated mechanism has been explicitly demonstrated via control experiments This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Quality Control of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Quality Control of 4,4′-Methylenediphenol

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Transiently gene-modulated cell reporter for ultrasensitive detection of estrogen-like compounds in tap water was written by Ren, Yun;Zheng, Jing;Wang, Hailin. And the article was included in Chemosphere in 2022.Name: 4,4′-Methylenediphenol The following contents are mentioned in the article:

Abnormal elevation of indispensable steroid hormone estrogens and exposure to exogenous estrogen-like compounds pose adverse health effects to aquatic animals and human alike. These compounds generally display functionally important estrogenic activity even at extremely low picomolar concentrations In this study we identified one critical but lethal gene (TAF1) that remarkably represses estrogenic activity. This gene is selected as a candidate for genetically modulating an estrogen-responding cell line. To overcome its lethality, instead of adopting a gene knockout strategy, we developed a transient TAF1 depletion strategy using a designed small interfering RNA. By the transient knockdown of TAF1 in the estrogen-responding reporter cell line, the maximum induction signals for endogenous estrogen 17β-estradiol (E2) and environmental estrogens 17α-ethynyl estradiol (EE2) and bisphenol compounds were enhanced by 4.8-13.3 folds. The limit of detection for EE2 is about 8 x 10-15 mol/L. Moreover, by the established method, trace estrogenic activity (14.7-24.2 pg E2 equiv (E2Eq)/L) can be detected in a portion of Tap water samples. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Name: 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Name: 4,4′-Methylenediphenol

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Next-generation biomonitoring of the early-life chemical exposome in neonatal and infant development was written by Jamnik, Thomas;Flasch, Mira;Braun, Dominik;Fareed, Yasmin;Wasinger, Daniel;Seki, David;Berry, David;Berger, Angelika;Wisgrill, Lukas;Warth, Benedikt. And the article was included in Nature Communications in 2022.Related Products of 620-92-8 The following contents are mentioned in the article:

Exposure to synthetic and natural chems. is a major environmental risk factor in the etiol. of many chronic diseases. Investigating complex co-exposures is necessary for a holistic assessment in exposome-wide association studies. In this work, a sensitive liquid chromatog.-tandem mass spectrometry approach was developed and validated. The assay enables the anal. of more than 80 highly-diverse xenobiotics in urine, serum/plasma, and breast milk; with detection limits generally in the pg-ng mL-1 range. In plasma of extremely-premature infants, 27 xenobiotics are identified; including contamination with plasticizers, perfluorinated alkylated substances and parabens. In breast milk samples collected longitudinally over the first 211 days post-partum, 29 analytes are detected, including pyrrolizidine- and tropane alkaloids which have not been identified in this matrix before. A preliminary estimation of daily toxicant intake via breast milk is conducted. In conclusion, we observe significant early-life co-exposure to multiple toxicants, and demonstrate the method′s applicability for large-scale exposomics-type cohort studies. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Related Products of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Related Products of 620-92-8

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rational design of 2D ultrathin BiO(HCOO)_xI_1-x composite nanosheets: The synergistic effect of ultrathin structure and hybridization in the effective elimination of BPA under visible light irradiation was written by Wang, Qiao;Lv, Guanheng;Cao, Yiting;Chen, Zhenhui;Jia, Jialin;Qin, Yanlin;Lin, Zhenxuan;Xie, Xuan;Wang, Zhihong. And the article was included in Separation and Purification Technology in 2022.Safety of 4,4′-Methylenediphenol The following contents are mentioned in the article:

Here, a novel series of 2D bismuth oxide formate-x composites were first fabricated with a ultrathin thickness (∼2.47 nm). Among them, the optimal BiO(HCOO)_0.75I_0.25 nanosheets exhibited a superior photocatalytic performance with the kinetic constant reaching up to 0.2148 min-1, which was 5.9, 97.6 and 27.2 folds higher than that of pristine BiOI, BiOCOOH and BiO(HCOO)_0.75I_0.25-P nanoplates, resp. Benefiting from the synergistic effect of ultrathin two-dimensional structure and hybrid composite, the photocatalytic performance was signally improved. Based on the optical and photoelectrochem. characterizations, the fabrication of hybrid composite delivered the optimal balance of visible-light absorption and redox capacity, endowing the photoinduced holes a higher oxidation potential. Meanwhile, the construction of 2D ultrathin structure reduced the migration distance of charge carriers, consequently accelerated those separated rate. This study provides a new insight for designing high active Bi-based photocatalysts, which is hopeful to make a great contribution to aquatic environmental restoration. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Safety of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Safety of 4,4′-Methylenediphenol

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Alcohol – Wikipedia,
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Toxicological profile of bisphenol F via comprehensive and extensive toxicity evaluations following dermal exposure was written by Lee, Sang-Sik;Ryu, Hyeon-Yeol;Ahn, Kyu-Sup;Lee, Somin;Lee, Jiho;Lee, Jae Won;Ko, Soo Min;Son, Woo-Chan. And the article was included in Journal of Toxicology and Environmental Health in 2022.Category: alcohols-buliding-blocks The following contents are mentioned in the article:

Bisphenol F (BPF) is classified as a harmful substance by the U. S. Environmental Protection Agency. Although previous studies focused on human exposure to BPF via direct consumption or inhalation, few investigators assessed potential toxicol. effects following skin contact. The aim of this study was to examine (1) the degree and pattern by which BPF is absorbed onto the skin in vivo, and (2) determination of toxicity and safety using the following tests: acute dermal; a 28-day repeat dermal; a skin irritation; an eye irritation; and a skin sensitization. As indicated by the amount of BPF remaining in the epidermis or dermis, data demonstrated that BPF was absorbed through the skin at a 26.5% rate. BPF penetrated the s.c. layer at a “fast rate” (Kp: 2.2E-02). Although no toxicol. changes or local irritation were observed following skin exposure, BPF induced potent sensitization. In summary, the findings of this study showed that BPF penetrated and was absorbed into the skin at a high rate which was associated with enhanced chem.-induced skin sensitization and this may have significant implications following exposure of skin to BPF. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Category: alcohols-buliding-blocks).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
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Bisphenol A and its structural analogues in infant formulas available in the Brazilian market: Optimisation of a UPLC-MS/MS method, occurrence, and dietary exposure assessment was written by Petrarca, Mateus Henrique;Perez, Mary Angela Favaro;Tfouni, Silvia Amelia Verdiani. And the article was included in Food Research International in 2022.SDS of cas: 620-92-8 The following contents are mentioned in the article:

For the first time, structural analogs to bisphenol A were investigated in infant formulas marketed in Brazil. A fast and high throughput UPLC-MS/MS method was established for simultaneous anal. of bisphenol A, B, E, F, and S in complex infant formula matrixes. The influence of mobile phase composition on electrospray ionization response in neg. mode was studied to improve the detectability of the method. As also, the main sample preparation variables that could affect the extraction and cleanup were screened by the Plackett-Burman design. The method performance characteristics were adequate, including reliable limits of detection (5-10 μg kg-1) and quantification (10-20 μg kg-1) with suitable recoveries (84.2-108.9 %) and precision (≤18 %). Sixty-one infant formulas were analyzed, and 36 % of total samples contained at least one bisphenol analog, whose levels ranged between 10.9 and 198.9 μg kg-1. Based on a deterministic approach, the estimated daily intakes for babies up to 6 mo old, fed exclusively with infant formula, were below the temporary tolerable daily intake of 4 μg kg-1 body weight set for bisphenol A by the European Food Safety Authority. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8SDS of cas: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.SDS of cas: 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts