Category: 620-92-8

Occurrence of bisphenols and benzophenone UV filters in wild brown mussels (Perna perna) from Algoa Bay in South Africa was written by Castro, Gabriela;Fourie, Amarein J.;Marlin, Danica;Venkatraman, Vishwesh;Gonzalez, Susana V.;Asimakopoulos, Alexandros G.. And the article was included in Science of the Total Environment in 2022.Category: alcohols-buliding-blocks The following contents are mentioned in the article:

Bisphenols and benzophenone UV filters are contaminants present in a wide variety of plastic materials and consumer products. The scientific attention towards these contaminants has increased in recent years due to their presence in microplastics, their ubiquitous occurrence in the environment, and their known endocrine disrupting health effects. In this study, the occurrence of nine bisphenol and five benzophenone UV-filter analogs was assessed in wild brown mussels (Perna perna) collected from different sampling sites along the coast of Algoa Bay, South Africa. Eleven out of fourteen target analytes were detected, and bisphenol AP (BPAP) was detected for the first time in mussels, presenting the highest median concentration of 150 ng g^-1 dry weight (d.w.) and a detection frequency of 91%. Regarding benzophenone UV-filters, median concentrations of the analogs (across all sites) ranged from 2.01 to 10.6 ng g^-1 d.w., with benzophenone-1 (BzP^-1) and benzophenone-3 (BzP-3) presenting the highest concentrations Human exposure was assessed by estimating daily intakes (EDI) of the target analytes through mussel consumption. To our knowledge, this is the first study from the African continent on the occurrence of bisphenols and benzophenone UV-filters in a large population (n=138) of wild brown mussels. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Category: alcohols-buliding-blocks).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Computational risk assessment framework for the hazard analysis of bisphenols and quinone metabolites was written by Pandit, Shraddha;Singh, Prakrity;Parthasarathi, Ramakrishnan. And the article was included in Journal of Hazardous Materials in 2022.Application In Synthesis of 4,4′-Methylenediphenol The following contents are mentioned in the article:

Bisphenol A (BPA) is a widely used chem. in plastics but its proven harmful effects has led to the replacement and production of its analogs that might also induce hazard as well as associated risks. To elucidate the adverse impact of the BPA analogs, a comprehensive computational framework is developed which applies toxicogenomics aligned with D. Functional Theory (DFT) and Mol. Dynamics (MD) based approaches to understand the toxic potential of quinone metabolites of Bisphenol F (BPF) and 3,3′-dimethylbisphenol A (DMBPA). The obtained results indicate a similar chem. reactivity profile for these metabolites of bisphenols to BPA metabolite. MD simulation revealed that the quinone metabolites tend to interact with the DNA comprising hydrogen bonding, van der Waals forces, and electrostatic interactions as an onset for covalent binding to adduct formation. Structural anal. suggests that interactions with DC9, DG10, DG16, DA17, DA18, and DT19 play a crucial role in stabilizing the quinone metabolite in the interactive pocket of DNA. These observations are demonstrating that BPF and DMBPA have the potential to impose genotoxicity via forming the quinone metabolite adducts. Combination of DFT and MD-based computational approaches providing a structure-activity-toxicity spectrum of chems. can serve for the purpose of risk assessment. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Application In Synthesis of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application In Synthesis of 4,4′-Methylenediphenol

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Multi-analyte gas chromatography-mass spectrometry method to monitor bisphenols, musk fragrances, ultraviolet filters, and pesticide residues in seafood was written by Petrarca, Mateus Henrique;Fernandes, Jose O.;Marmelo, Isa;Marques, Antonio;Cunha, Sara C.. And the article was included in Journal of Chromatography A in 2022.Category: alcohols-buliding-blocks The following contents are mentioned in the article:

A gas chromatog.-mass spectrometry method for the anal. of thirty-six anthropogenic contaminants in the edible portion of four distinct seafood items is reported. Considering the heterogeneous composition of algae, mussels, and lean/fatty fish muscles, a generic sample preparation based on the QuEChERS procedure combined with dispersive liquid-liquid microextraction (DLLME) with in situ acetylation was successfully applied for quantification of pesticide residues, bisphenols, musk fragrances and UV-filters. Matrix effects were influenced by the type of seafood, with the lowest effects being observed with EMR-lipid and graphitized carbon black sorbents in dispersive solid-phase extraction cleanup step. Method performance features were successful evaluated in the different seafood samples – algae, mussel, lean and fatty fish muscles, following the criteria established by SANTE/12682/2019 for anal. methods for pesticide residues anal. The detection and quantification of bisphenol F, musk fragrances (galaxolide and tonalide), UV-filters (2-ethylhexyl salicylate, 2-ethylhexyl 4-methoxycinnamate, and isoamyl 4-methoxycinnamate), and residues of permethrin in com. samples of algae, mussel and fish collected in a Portuguese estuary support the suitability of the proposed method for future seafood monitoring by food safety authorities. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Category: alcohols-buliding-blocks).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A flexible thermoelectric film based on Bi₂Te₂ for wearable applications was written by Liu, Changxin;Zhao, Kaiyuan;Fan, Yuhang;Gao, Yu;Zhou, Zhenghui;Li, Mengze;Gao, Yunfei;Han, Zhitao;Xu, Minyi;Pan, Xinxiang. And the article was included in Functional Materials Letters in 2022.Safety of 4,4′-Methylenediphenol The following contents are mentioned in the article:

In recent years, with the development of the Internet of Things (IoT) and wearable technol., the research and exploration of thermoelec. materials have been greatly promoted. However, traditional thermoelec. materials are rigid and brittle. Thermoelec. devices made of these materials usually cannot be closely attached to the heat and cold sources that provide temperature differences, thus limiting the application of thermoelec. materials. Therefore, manufacturing new high-performance flexible thermoelec. devices is still a huge challenge. In this work, polyimide/copper (PI/Cu) substrate was deposited by electron deposition technol. The flexible thermoelec. thin film device was fabricated by bonding N-type and P-type bismuth telluride (Bi₂Te₂) slurries onto the PI/Cu substrate. Then, the PDMS film was coated on the device to make the device waterproof and oxidation resistant. The output voltage and maximum power of this device, at the temperature of 80 K, reach 97.5 mV and 60 uW, resp. After 200 cycles of cyclic bending experiments, 90% high conductivity retention can be maintained. It demonstrates that the new flexible thermoelec. thin film has good flexibility and excellent stability. This work provides a simple method for the preparation of flexible thermoelec. thin films and opens up a new way for its application in the sensing equipment and wearable device of the IoT. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Safety of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Optimization of an ultrasound-assisted extraction method for the determination of parabens and bisphenol homologues in human saliva by liquid chromatography-tandem mass spectrometry was written by Moscoso-Ruiz, Inmaculada;Galvez-Ontiveros, Yolanda;Cantarero-Malagon, Samuel;Rivas, Ana;Zafra, Alberto. And the article was included in Microchemical Journal in 2022.Formula: C13H12O2 The following contents are mentioned in the article:

Parabens and bisphenols are endocrine disrupting chems. (EDCs) widely used in our daily lives. The main route of human exposure to these compounds is through the diet. This makes human saliva an important matrix for identification of these contaminants and evaluation of human exposure. In this work a multiresidue method to det the presence of methyl-, ethyl-, propyl-, isopropyl-, butyl- and isobutylparaben; and bisphenol A, B, C, E, F, M, P, S, Z, AP, AF and FL in human saliva samples has been developed. Sample treatment involves an initial step of protein pprotein in acidic medium and a second step of analyte extraction Extraction parameters were optimized using univariant and multivariant strategies. Microwave assisted extraction (MAE) and ultrasound assisted extraction (UAE) were compared and UAE was chosen the optimal extraction technique. The compounds were analyzed by ultra-high performance liquid chromatog. coupled to tandem mass spectrometry (UHPLC-MS/MS). The calibration in matrix was applied and the limits of detection and quantification were from 0.1 to 0.4 ng g-1 and from 0.3 to 1.0 ng g-1, respectivley. Accuracy was evaluated in terms of recovery (85.6 to 113.5%) with a relative standard deviation < 15% in all cases. The anal. method was successfully applied to quantify the target EDCs in ten human saliva samples, with some parabens being the most frequently detected compounds This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Formation and nature of non-extractable residues of emerging organic contaminants in humic acids catalyzed by laccase was written by Zhou, Yue;Sun, Feifei;Wu, Xuan;Cao, Siqi;Guo, Xiaoran;Wang, Qilin;Wang, Yongfeng;Ji, Rong. And the article was included in Science of the Total Environment in 2022.Synthetic Route of C13H12O2 The following contents are mentioned in the article:

Formation of non-extractable residues (NERs) is the major fate of most environmental organic contaminants in soil, however, there is no direct evidence yet to support the assumed phys. entrapment of NERs (i.e., type I NERs) inside soil humic substances. Here, we used ¹⁴C-radiotracer and silylation techniques to analyze NERs of six emerging and traditional organic contaminants formed in a suspension of humic acids (HA) under catalysis of the oxidative enzyme laccase. Laccase induced formation of both type I and covalently bound NERs (i.e., type II NERs) of bisphenol A, bisphenol F, and tetrabromobisphenol A to a large extent, and of bisphenol S (BPS) and sulfamethoxazole (SMX) to a less extent, while no induction for phenanthrene. The type I NERs were formed supposedly owing to laccase-induced alteration of primary (active groups) and secondary (conformation) structure of humic supramols., contributing surprisingly to large extents (23.5%-65.7%) to the total NERs, particularly for BPS and SMX, which both were otherwise not transformed by laccase catalysis. Electron-withdrawing sulfonyl group and bromine substitution significantly decreased amount and kinetics of NER formation, resp. This study provides the first direct evidence for the formation of type I NERs in humic substances and implies a “Trojan horse” effect of such NERs in the environment. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Synthetic Route of C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Synthetic Route of C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

New method for the determination of endocrine disrupting chemicals in Mediterranean mussel (Mytilus galloprovincialis) using ultra-high performance liquid chromatography-tandem mass spectrometry was written by Garcia-Fernandez, L.;Garcia-Corcoles, M. T.;Navalon, A.;Martin-Pozo, L.;Hidalgo, F.;Zafra-Gomez, A.. And the article was included in Microchemical Journal in 2022.Recommanded Product: 4,4′-Methylenediphenol The following contents are mentioned in the article:

There are numerous types of contaminants that pose a health risk to aquatic organisms and consequently also to humans through consumption. Endocrine disrupting compounds are found in daily-use products and have the potential to mimic natural hormones. The main objective of this work is to optimize and validate a method for the determination of bisphenols, parabens and triclocarban in natural samples of Mediterranean mussel (Mytilus galloprovincialis). The procedure involves ultrasound-assisted extraction (UAE), and a subsequent clean-up of the extracts using dispersive solid phase extraction (d-SPE) with C18 adsorbent, and anal. by ultrahigh performance liquid chromatog.-tandem mass spectrometry (UHPLC-MS/MS). Sensitivity, accuracy (trueness and precision), linearity and selectivity of the method were studied. The limits of detection ranged from 0.2 ng g-1 to 1.5 ng g-1 dry weight The trueness of the method (estimation of recovery) was between 90 % for TCC (triclocarban) and 109.6 % for BPP (bisphenol P), with an estimated precision lower than 12.6 % for all the investigated analytes. The application of the method was to specimens of Mytilus galloprovincialis collected along the Mediterranean coast of Granada (South Spain), where the species is abundant. The study conducted in different sample sites revealed EDCs presence in this aquatic species. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Recommanded Product: 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Two photosensitive chalcone-based benzoxazine monomers and their high-performance polymers from renewable sources was written by Feng, Zijian;Zeng, Ming;Tan, Dengru;Lu, Xiang;Shen, Yufang;Xu, Qingyu;Meng, Dawei. And the article was included in Journal of Materials Science in 2022.COA of Formula: C13H12O2 The following contents are mentioned in the article:

Two novel photosensitive bio-based benzoxazines are firstly synthesized from chalcone derivates and furfurylamine. The thermal and photo-thermal curing methods are applied to polymerize benzoxazine monomers. Both thermal and photo-thermal cured benzoxazine resins exhibit high glass transition temperatures and good thermal stability properties, resulting from the curing of double bond of chalcone moiety and substitution reaction of furan ring for the thermal cured resins, and photo-dimerization of chalcone structure and grafting reaction of furan ring for the photo-thermal cured samples. It is especially noteworthy that the photo-thermal curing method is good for the formation of cyclobutane ring upon irradiation, resulting in the improvement of crosslinking d. and the reduction in the mol. polarity. Hence, the photo-thermal cured resins present higher glass transition temperatures and lower superhigh-frequency dielec. constants than those of the corresponding thermal cured samples. Therefore, this work not only provides an effective strategy for the design and preparation of high-heat-resistance bio-based benzoxzine resins with superhigh-frequency low dielec. constants, but also provides insight into the effects of photosensitive chalcone moiety and reactive furan ring as well as curing methods on the curing behavior, and thermal and superhigh-frequency dielec. properties of bio-based benzoxazine resins. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8COA of Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cardanol and bisphenol-F based benzoxazines with zirconium phosphate reinforced composites coating for protecting the mild steel surface from corrosion was written by Latha, Govindraj;Hariharan, Arumugam;Balaji, Krishnasamy;Kumaravel, Ammasai;Alagar, Muthukaruppan. And the article was included in Journal of Macromolecular Science.Application of 620-92-8 The following contents are mentioned in the article:

The present work is to develop and characterize the benzoxazines from cardanol and bisphenol-F with imdazole core based amine in order to utilize them in the form of (50/50 wt%) blended composites coating for corrosion resistance application. The benzoxazine blends were reinforced with varying weight percentages of (0.5, 1, 1.5, 2.0 and 2.5 wt%) of 3-glycidoxypropyltrimethoxysilane (GPTMS) functionalized zirconium phosphate (ZrP) to obtain resp. composites blended coatings. The thermal stability of composites was studied by thermogravimetric anal. (TGA). In order to ascertain their hydrophobic behavior the water contact angle studies were carried out and the values obtained for 0.5, 1, 1.5, 2.0 and 2.5 wt% GPTMS functionalized ZrP reinforced (50/50 wt% of C-ima/BF-ima) benzoxazines blended composites are 114,116,117,119,120 and 123° resp. The UV shielding behavior of ZrP reinforced polybenzoxazine blended composites material was also studied by UV-Vis spectroscopic technique and the results obtained infer that these materials possess good UV shielding behavior. ZrP reinforced benzoxazine blended composites were coated on the mild steel specimens and their corrosion resisting behavior was studied. of Nyquist plot and Tafel plot, ascertain that among the coated specimens, the specimen coated with 2.5 wt% ZrP reinforced poly(C-ima/BF-ima) blended composites exhibits highest corrosion resisting efficiency. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Application of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application of 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bisphenol F exposure affects mouse oocyte in vitro maturation through inducing oxidative stress and DNA damage was written by Ding, Zhi-Ming;Chen, Yang-Wu;Ahmad, Muhammad Jamil;Wang, Yong-Sheng;Yang, Sheng-Ji;Duan, Ze-Qun;Liu, Ming;Yang, Cai-Xia;Liang, Ai-Xin;Hua, Guo-Hua;Huo, Li-Jun. And the article was included in Environmental Toxicology in 2022.Category: alcohols-buliding-blocks The following contents are mentioned in the article:

Bisphenol F (BPF), a substitute for bisphenol A (BPA), is progressively used to manufacture various consumer products. Despite the established reproductive toxicity of BPF, the underlying mechanisms remain to elucidate. This in-vitro study deep in sighted the BPF toxicity on mouse oocyte meiotic maturation and quality. After treating oocytes with BPF (300μM), the oocyte meiotic progression was blocked, accentuated by a reduced rate in the first polar body extrusion (PBE). Next, we illustrated that BPF induced α-tubulin hyper-acetylation disrupted the spindle assembly and chromosome alignment. Concurrently, BPF resulted in severe oxidative stress and DNA damage, which triggered the early apoptosis in mouse oocytes. Further, altered epigenetic modifications following BPF exposure were proved by increased H3K27me3 levels. Concerning the toxic effects on spindle structure, oxidative stress, and DNA damage in mouse oocytes, BPF toxicity was less severe to oocyte maturation and spindle structure than BPA and induced low oxidative stress. However, compared with BPA, oocytes treated with BPF were more prone to DNA damage, indicating not less intense or even more severe toxic effects of BPF than BPA on some aspects of oocytes maturation. In brief, the present study established that like wise to BPA, BPF could inhibit meiotic maturation and reduce oocyte quality, suggesting it is not a safe substitute for BPA. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Category: alcohols-buliding-blocks).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts