Category: 620-92-8

A simple method for predicting the gas-chromatographic retention indices of phenolic derivatives was written by Pouretedal, Hamid Reza;Jafari, Mohammad. And the article was included in Journal of the Iranian Chemical Society.COA of Formula: C13H12O2 The following contents are mentioned in the article:

A simple approach is proposed to predict the gas-chromatog. retention indexes in nonpolar columns for a wide range of phenolic derivatives, through their mol. structures and independent of temperature data and active phase of column. The new model is based on the number of atoms and some structural moieties which depend on intra- and intermol. interactions. The present method can be easily applied for many kinds of phenolic compounds containing different substituents without using special computer codes, which need expert users. A big pool of the exptl. data (335 compounds) of retention indexes is used to construct the new model (80% for training set and 20% for test set). Different statistical parameters including the coefficient of determination, R2 (= 0.9482), root mean squared error, RMSE (= 89.01), and mean absolute percent error, MAPE (= 4.494), are used to investigate the reliability of the model, through both internal and external validation techniques. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8COA of Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.COA of Formula: C13H12O2

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Alcohol – Wikipedia,
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Hollow fiber membrane-protected amino/hydroxyl bifunctional microporous organic network fiber for solid-phase microextraction of bisphenols A, F, S, and triclosan in breast milk and infant formula was written by Li, Shihuan;Feng, Senwei;Van Schepdael, Ann;Wang, Xu. And the article was included in Food Chemistry in 2022.Recommanded Product: 620-92-8 The following contents are mentioned in the article:

Bisphenols and triclosan have been used in various products, and exposure to these chems. may affect human health. The present study proposes a sensitive method for the determination of bisphenols A, F, S, and triclosan. The fiber was coated by amino/hydroxyl bifunctional microporous organic network and protected by polyvinylidene fluoride hollow fiber membrane for direct immersion solid phase microextraction The limit of detection was 0.005μg/L (μg/kg), and the recoveries were in the range of 76.7% to 107.5% (87.4% to 107.6%) for breast milk (infant formula), with intra-day and inter-day precisions <10.5% (7.3%) and 13.6% (8.4%), resp. Fiber-to-fiber reproducibility of < 9.5% and a lifespan of >100 cycles were obtained. The 95th percentile estimated daily intake of total bisphenols was close to temporary tolerable daily intake for infants fed by human milk, which highlighted the needs for further attention on human exposure to BPA and its substitutes. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Recommanded Product: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 620-92-8

Referemce:
Alcohol – Wikipedia,
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BPA and its analogs increase oxidative stress levels in in vitro cultured granulosa cells by altering anti-oxidant enzymes expression was written by Sabry, R.;Nguyen, M.;Younes, S.;Favetta, L. A.. And the article was included in Molecular and Cellular Endocrinology in 2022.Formula: C13H12O2 The following contents are mentioned in the article:

Bisphenol A is a widespread endocrine disruptor with numerous effects on reproductive functions. Limitations on BPA in manufacturing has prompted the use of analogs, such as BPS and BPF, with limited research on their safety. The objective of this study was to evaluate the effects of BPA and its analogs on oxidative stress levels within bovine granulosa cells and to measure the expression of key antioxidant genes. Results indicate that BPA and BPF reduce cell viability and induce mitochondrial dysfunction and all three bisphenols increased production of reactive oxygen species as early as 12h post exposure. BPA increased the levels of antioxidants at 12h at the mRNA and protein levels, while these results were not significant at 48h. These results together suggest that BPA and its analogs can induce oxidative stress within bovine granulosa cells, although not necessarily through common mechanisms. Therefore, the use of BPA analogs may have to be re-considered. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Formula: C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Formula: C13H12O2

Referemce:
Alcohol – Wikipedia,
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A novel polyhedral oligomeric silsesquioxane-based hybrid monolith as a sorbent for on-line in-tube solid phase microextraction of bisphenols in milk prior to high performance liquid chromatography-ultraviolet detection analysis was written by Liu, Jie;Liu, Qian;Wei, Liulin;Chen, Xiaomei;Li, Zhiqiang;Xu, Yidong;Gao, Xueyun;Lu, Xiaoxiao;Zhao, Jingchan. And the article was included in Food Chemistry in 2022.Product Details of 620-92-8 The following contents are mentioned in the article:

An online in-tube solid-phase microextraction (in-tube SPME) coupled with high-performance liquid chromatog. (HPLC) method was proposed based on a novel polyhedral oligomeric silsesquioxane (POSS)-hybrid monolith for the determination of four bisphenols (BPs) in milk. The monolith was synthesized using acrylamide (AM) and monomethacrylate-functionalized POSS (mono-MA-POSS) as functional monomers to copolymerize with ethylene dimethacrylate (EDMA). Due to the abundant hydrogen bonding, π-π and hydrophobic interaction sites, the synthetic monolith displayed satisfying extraction performance for target BPs. Under the optimized conditions, the developed online in-tube SPME-HPLC method exhibited low limits of detection (LODs) (0.030-0.055 ng mL^-1). The spiked recoveries were between 85.4 % and 111.8 %, and the relative standard deviations (RSDs) were less than 3.5 % for all the analytes. The results showed that the proposed method provided alternative for the anal. of BPs in complex samples. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Product Details of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Product Details of 620-92-8

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Alcohol – Wikipedia,
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Banana-peel-derived magnetic porous carbon as effective adsorbent for the enrichment of six bisphenols from beverage and water samples was written by Liang, Ming;Hou, Xiangchang;Xian, Yanping;Wu, Yuluan;Hu, Junpeng;Chen, Rongqiao;Wang, Li;Huang, Yufeng;Zhang, Xiaoli. And the article was included in Food Chemistry in 2022.Quality Control of 4,4′-Methylenediphenol The following contents are mentioned in the article:

Functionalized magnetic nanoporous carbon derived from banana peel was synthesized through carbonization, porogenesis, carboxylation and magnetization using banana peel and was successfully used as a magnetic solid phase extraction (MSPE) material for the enrichment of six bisphenols (BPs) from beverage and water samples. After the optimization of MSPE process, the enrichment factors of six target analytes were in the range of 74-112 for water samples, and 15-22 for beverage samples. Then, high-performance liquid chromatog.-quadrupole-Orbitrap high-resolution mass spectrometry (HPLC-Q Orbitrap-HRMS) was used for the separation and determination of the target analytes. Results showed that the extraction recoveries for 6 BPs were in the range of 71.9-108.4% with an RSD of 2.5-7.5% (n = 6). These results demonstrated that the as-prepared material could efficiently enrich some aromatic compounds and the proposed method is reliable and robust for the determination of BPs in water and beverage samples. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Quality Control of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Quality Control of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Microplastics, bisphenols, phthalates and pesticides in odontocete species in the Macaronesian Region (Eastern North Atlantic) was written by Montoto-Martinez, Tania;De la Fuente, Jesus;Puig-Lozano, Raquel;Marques, Nuno;Arbelo, Manuel;Hernandez-Brito, Jose Joaquin;Fernandez, Antonio;Gelado-Caballero, Maria Dolores. And the article was included in Marine Pollution Bulletin in 2021.Reference of 620-92-8 The following contents are mentioned in the article:

The gastrointestinal contents of twelve individuals from six odontocete species that stranded between 2018 and 2019 in the Macaronesian Region (Eastern North Atlantic) were examined for the presence of marine debris. In addition, concentrations of eleven organic persistent contaminants (nonylphenols, bisphenols, phthalates and pesticides) were analyzed in muscle samples by liquid chromatog. No particles larger than 5 mm were found, except for two plastic labels that were found on the same dolphin. On the contrary, all animals contained microplastics of diverse sizes, most of them being fibers (98.06%, n = 708). The predominant detected pollutants were bisphenols (4-984 ng/g) and DEHP (102-1533 ng/g). Also, except for two individuals, all animals had pesticide levels in their tissues. This work has allowed the establishment of a protocol for the study of microplastic ingestion in cetaceans, and tests the potential of microRaman to improve the understanding of microplastic alteration processes. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Reference of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Reference of 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bisphenols induce human genomic damage and modulate HERVs /env expression was written by Ruberto, Stefano;Santovito, Alfredo;Simula, Elena R.;Noli, Marta;Manca, Maria A.;Sechi, Leonardo A.. And the article was included in Environmental and Molecular Mutagenesis in 2022.Recommanded Product: 620-92-8 The following contents are mentioned in the article:

Bisphenol A (BPA), a recognized endocrine-disrupting chem., is used in the production of epoxy and polycarbonate resins. Since human exposure to BPA has been associated with increased cancer susceptibility, the market has shifted to products often labeled as “BPA free” containing BPA analogs such as bisphenol F (BPF) and bisphenol S (BPS). However, the European legislation on BPF and BPS is still unclear. This study analyzed the effects of BPA, BPF, and BPS exposure on human peripheral blood mononuclear cells by using in vitro micronucleus assay. Furthermore, it investigated the impact of bisphenols exposure on human endogenous retroviruses (HERVs) expression, which is implicated with the pathogenesis of several human diseases. The micronucleus assay revealed a significant genotoxic effect in peripheral blood cells after exposure to BPA and BPF at concentrations of 0.1, 0.05, and 0.025μg/mL, and to BPS at 0.1 and 0.05μg/mL. In addition, BPA exposure seems to upregulate the expression of HERVs, while a downregulation was observed after BPF and BPS treatments. Overall, our data showed the toxic effect of BPA and its analogs on circulating cells in the blood and demonstrated that they could modulate the HERVs expression. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Recommanded Product: 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Recommanded Product: 620-92-8

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Alcohol – Wikipedia,
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C-O band structure modified broad spectral response carbon nitride with enhanced electron density in photocatalytic peroxymonosulfate activation for bisphenol pollutants removal was written by Tong, Chun;Jing, Liquan;Xie, Meng;He, Minqiang;Liu, Ying;Yuan, Junjie;Song, Yanhua;Xu, Yuanguo. And the article was included in Journal of Hazardous Materials in 2022.Computed Properties of C13H12O2 The following contents are mentioned in the article:

Here, a simple one-step calcination method uses glycolic acid (GA) and urea to synthesize C-O band structure modified carbon nitride with broad spectral response, which is used to construct a peroxymonosulfate/visible light (PMS/vis) system. The solid-state ¹³C NMR proved that C-O band structure was successfully introduced into the carbon nitride. D. functional theory (DFT) calculation show that the introduction of C-O band structure shortens the band gap of 0.05 g GA modified CN (0.05 GA-CN). Besides, UPS (UPS) further illustrate that the 0.05 GA-CN has a higher charge d. and promotes the degradation of pollutants. In PMS/vis system, 0.05 GA-CN can completely degrade bisphenol A (BPA) within 36 min. In addition, 0.05 GA-CN can also degrade bisphenol E (BPE) and bisphenol F (BPF). The cyclic voltammetry (CV) curve show that the introduction of C-O band structure enhances the activation ability of PMS. At the same time, 0.05 GA-CN/PMS has enhanced the activity of degrading BPA under blue light (450-462 nm), green light (510-520 nm) and red light (610-625 nm). This research provides a new method to synthesize carbon nitride with enhanced electron d. for degradation of bisphenol pollutants in PMS/vis system. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Computed Properties of C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Computed Properties of C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Assessing microplastic ingestion and occurrence of bisphenols and phthalates in bivalves, fish and holothurians from a Mediterranean marine protected area was written by Rios-Fuster, Beatriz;Alomar, Carme;Paniagua Gonzalez, Gema;Garcinuno Martinez, Rosa Maria;Soliz Rojas, Dulce Lucy;Fernandez Hernando, Pilar;Deudero, Salud. And the article was included in Environmental Research in 2022.Application of 620-92-8 The following contents are mentioned in the article:

Microplastic (MP) ingestion, along with accumulated plasticizers such as bisphenol A (BPA), bisphenol F (BPF), and bisphenol S (BPS), and phthalates represented by di-Et phthalate (DEP), di-Bu phthalate (DBP) and bis (2-ethylhexyl) phthalate (DEHP), were quantified in bivalves, fish, and holothurians collected from a coastal pristine area at the western Mediterranean Sea. MP ingestion in sediment-feeders holothurians (mean value 12.67 ± 7.31 MPs/individual) was statistically higher than ingestion in bivalves and fish (mean 4.83 ± 5.35 and 3 ± 4.44 MPs/individual, resp.). The main ingested polymers were polyethylene, polypropylene, and polystyrene. The levels of BPS, BPF, and DEHP were highest in bivalves soft tissue; BPA and DBP had the highest levels in the holothurians muscle. In addition, the levels of all plasticizers assessed were lowest in fish muscle; only BPA levels in fish were higher than in bivalves, with intermediate values between those of bivalves and holothurians. This provides data on exposure to MPs and plasticizers of different species inhabiting Cabrera Marine Protected Area (MPA) and highlights the differences in MP ingestion and levels of plasticizers between species with different ecol. characteristics and feeding strategies. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Application of 620-92-8).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application of 620-92-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Elevated levels of perfluoroalkyl substances in breast cancer patients within the Greater Manila Area was written by Velarde, Michael C.;Chan, Alison Faye O.;Sajo, Ma Easter Joy V.;Zakharevich, Igor;Melamed, Jonathan;Uy, Gemma Leonora B.;Teves, Joji Marie Y.;Corachea, Allen Joy M.;Valparaiso, Apple P.;Macalindong, Shiela S.;Cabaluna, Nelson D.;Dofitas, Rodney B.;Giudice, Linda C.;Gerona, Roy R.. And the article was included in Chemosphere in 2022.Electric Literature of C13H12O2 The following contents are mentioned in the article:

Several studies have reported exposure of humans to various endocrine disrupting chems. (EDCs) worldwide. However, there is a lack of data regarding EDC exposures in humans living in Southeast Asian countries, such as the Philippines. Hence, this study measured levels of 41 EDCs in women residing in the Greater Manila Area, home to the second largest city in Southeast Asia. Urine samples from women with vs. without breast cancer were analyzed for 11 phthalate metabolites, 8 environmental phenols, and 10 bisphenols, while serum samples were analyzed for 12 perfluoroalkyl substances (PFAS). Out of the four groups of EDCs analyzed, PFAS were significantly associated with breast cancer (adjusted OR = 13.63, 95% CI: 3.24-94.88 p-trend = 0.001 for PFDoA; adjusted OR = 9.26, 95% CI 2.54-45.10, p-trend = 0.002 for PFDA; and adjusted OR = 2.66, 95% CI: 0.95-7.66, p-trend = 0.004 for PFHxA). Long-chain PFAS levels were pos. correlated with age and were significantly higher in women from Region IV-A, a heavily industrialized region, than from the National Capital Region. Overall, this study showed baseline information regarding the level of EDCs in Filipinas, providing a glimpse of EDC exposure in women living in a megalopolis city in Southeast Asia. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Electric Literature of C13H12O2).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Electric Literature of C13H12O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts