Category: 599-67-7

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 599-67-7, name is 1,1-Diphenylethanol. This compound has unique chemical properties. The synthetic route is as follows. name: 1,1-Diphenylethanol

General procedure: In a vacuum dried 100 mL Schlenk flask, benzyl alcohol I (10.0 mmol) and triethylamine(20.0 mmol) were dissolved in THF (50 mL) under Ar atmosphere. Then, HClSiMe2 (12 mmol)was added at room temperature and the resulting mixture was stirred overnight. After the reactionwas complete, the solvent was removed via rotary evaporation. Then, petroleum ether (40 mL)was added. Simple filteration to remove Et3N?HCl and concentration in vacuo could give the pure(hydrido)silyl ether product as a colorless liquid.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 599-67-7, 1,1-Diphenylethanol.

Reference:
Article; Fang, Huaquan; He, Qiaoxing; Liu, Guixia; Huang, Zheng; Synlett; vol. 28; 18; (2017); p. 2468 – 2472;,
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In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 599-67-7, name is 1,1-Diphenylethanol, the common compound, a new synthetic route is introduced below. Recommanded Product: 599-67-7

acetophenone; 2- methyl tetrahydrofuran solution(including 42.6g acetophenone anhydrous ;2- methyltetrahydrofuran 30mL) Slow drop in at room temperature Example 4 ofPhenyl magnesium bromide Grignard reagent Dropfinish,Temperature rise to80 degrees Celsius reaction 3 Hours TLC Monitoring reactioncompletely, Cooling to 5 DEG C. Add 10% hydrochloric acid to the reaction solution pH=6 ~7, Room temperature continues to react for 1hours get the phenylethanol 2- methyltetrahydrofuran, Added 5.08g Sulfonic acidfunctional ionic liquid catalyst, [DBSDMI]OTf (structural formula II),Water separator device, Temperature rise to refluxdehydration reaction 0.5 hours TLC monitoring reaction is complete,Recovery solvent at atmospheric pressure – methyltetrahydrofuran, vacuum distillationresidue from 106 to 110 DEG /2mmHg fraction was colorless oily Liquid 61.3g, Yield was96%, GC content analysis 99.2%, GC test conditions and examples 1.;

The synthetic route of 599-67-7 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Zhejiang University of Technology; Shangyu Sunfit Chemical Co., Ltd; CHEN, ZHIWEI; SU, WEIKE; JING, LEI; HUANG, SHENGJIAN; CHEN, JIONGMING; (9 pag.)CN103755516; (2016); B;,
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Application of 599-67-7, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 599-67-7, name is 1,1-Diphenylethanol, molecular formula is C14H14O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

General procedure: A solvent (5 mL) was placed in a 10 mL round bottom-flask equipped with a magnetic stirrerunder reflux, NXS (1.1 mmol) was then added and, after being dissolved, the substrate (1 mmol) wasadded and the solution was stirred for 4-24 h. The progress of the reaction mixture was monitoredby TLC, whilst the consumption of NXS was tested by KI (0.1 M). Upon completion of the reaction,the crude reaction mixture was cooled down at room temperature, diluted with EtOAc (15 mL),washed with aqueous Na2S2O3 (6 mL), NaHCO3 (6 mL), and water (10 mL), and dried over anhydrousNa2SO4. The solvent was evaporated under reduced pressure and the crude product obtained wasanalyzed by 1H-NMR. The pure final products were obtained after flash chromatography, columnchromatography or preparative thin layer chromatography.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 599-67-7, 1,1-Diphenylethanol.

Reference:
Article; Ajvazi, Njomza; Stavber, Stojan; Molecules; vol. 21; 10; (2016);,
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Reference of 599-67-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 599-67-7, name is 1,1-Diphenylethanol. This compound has unique chemical properties. The synthetic route is as follows.

Into a 1-liter reaction flask were introduced 200.23 g of the crude 1,1-diphenylethanol obtained above, 400 ml of toluene, and 1 g of p-toluenesulfonic acid (PTSA). Azeotropic dehydration was conducted for 2 hours with toluene refluxing (94-116 C.). The resulting reaction mixture was cooled, washed with water and then with 2% soda ash solution, dried with magnesium sulfate, and concentrated to obtain 190.09 g of crude 1,1-diphenylethylene (4a; R1,R2 =H). This crude 1,1-diphenylethylene (4a) was distilled with a Claisen flask equipped with a vigreux (b.p., 103 C./1 mmHg), giving 174.06 g of 1,1-diphenylethylene (4a). The theoretical yield based on the benzophenone was 96.5%.

According to the analysis of related databases, 599-67-7, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Takasago International Corporation; US5573878; (1996); A;,
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Adding a certain compound to certain chemical reactions, such as: 599-67-7, 1,1-Diphenylethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 599-67-7, blongs to alcohols-buliding-blocks compound. Computed Properties of C14H14O

General procedure: A solvent (5 mL) was placed in a 10 mL round bottom-flask equipped with a magnetic stirrerunder reflux, NXS (1.1 mmol) was then added and, after being dissolved, the substrate (1 mmol) wasadded and the solution was stirred for 4-24 h. The progress of the reaction mixture was monitoredby TLC, whilst the consumption of NXS was tested by KI (0.1 M). Upon completion of the reaction,the crude reaction mixture was cooled down at room temperature, diluted with EtOAc (15 mL),washed with aqueous Na2S2O3 (6 mL), NaHCO3 (6 mL), and water (10 mL), and dried over anhydrousNa2SO4. The solvent was evaporated under reduced pressure and the crude product obtained wasanalyzed by 1H-NMR. The pure final products were obtained after flash chromatography, columnchromatography or preparative thin layer chromatography.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,599-67-7, its application will become more common.

Reference:
Article; Ajvazi, Njomza; Stavber, Stojan; Molecules; vol. 21; 10; (2016);,
Alcohol – Wikipedia,
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Reference of 599-67-7, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.599-67-7, name is 1,1-Diphenylethanol, molecular formula is C14H14O, molecular weight is 198.26, as common compound, the synthetic route is as follows.

General procedure: The procedure is the same for solid and liquid substrates.Alcohol (1 mmol) and iodine (3 mol%) weremixed together in a 5 mL conical reactor and the reactionmixture stirred at 25 C or 55 C for various times (5 minto 192 h), progress was monitored by TLC or by 1H NMRspectroscopy. The crude reaction mixture was dilutedwith tert-butyl methyl ether, washed with an aqueoussolution of Na2S2O3, water, dried over Na2SO4 and the solventevaporated under reduced pressure. The crude reactionmixture was subjected to column chromatography orpreparative TLC using hexane or petroleum ether/tert-butylmethyl ether mixtures and pure product(s) were obtained.Conversions were determined by 1H NMR spectroscopy.The effects of reaction variables on the type oftransformation and conversions are stated in Tables andFigures. In order to obtain the information (role) of thereaction variables and structure of substrate, the data (reactiontimes with lower conversion) are presented in someTables. In the experimental section, the best reaction conditionsare named; 3 mol% of I2 were used, giving thehighest yield.

Statistics shows that 599-67-7 is playing an increasingly important role. we look forward to future research findings about 1,1-Diphenylethanol.

Reference:
Article; Jereb, Marjan; Vra?i?, Dejan; Acta Chimica Slovenica; vol. 64; 4; (2017); p. 747 – 762;,
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Electric Literature of 599-67-7, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 599-67-7, name is 1,1-Diphenylethanol, molecular formula is C14H14O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

General procedure: Iodine (5.1 mg, 0.02 mmol) was added to phenol 1l (0.148 g, 1 mmol) or alcohol 3h (0.242 g, 1 mmol), followed by addition of HMDS (0.089 g, 0.55 mmol); the mixture was stirred at room temperature until the complete consumption of the starting material (TLC check). The crude reaction mixture was dissolved in 4 mL of hexane/TBME and stirred with the finely powdered Na2S2O3 until the disappearance of iodine. From this point on, two different scenarios are possible: a) The solids were filtered off and the solvent evaporated under the reduced pressure, yielding the crude product. In numerous cases, such products were practically pure; column chromatography and/or distillation improved their quality only slightly. b) A solution of a product in hexane/TBME mixture could be directly subjected to the column chromatography, without filtration of the solids. Caution: Although we experienced no problems when performing these reactions, care should taken due to the potential formation of NI3.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 599-67-7, 1,1-Diphenylethanol.

Reference:
Article; Jereb, Marjan; Tetrahedron; vol. 68; 20; (2012); p. 3861 – 3867;,
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Synthetic Route of 599-67-7 ,Some common heterocyclic compound, 599-67-7, molecular formula is C14H14O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General procedure: A mixture of 1 (2 mmol), 2 (4 or 15 mmol) and NaHSO4/SiO2 (2.1 mmol/g, 1.0 or 2.0g) in DCE (10 mL) was stirred at 80 C for 2 h, and then the used supported reagent was removed by filtration. The filtrate was evaporated to leave crude product, which was purified by column chromatography (hexane/chloroform) to obtain substituted chromans 3.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,599-67-7, its application will become more common.

Reference:
Article; Aoyama, Tadashi; Furukawa, Takuya; Hayakawa, Mamiko; Takido, Toshio; Kodomari, Mitsuo; Synlett; vol. 26; 13; (2015); p. 1875 – 1879;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 599-67-7, name is 1,1-Diphenylethanol, the common compound, a new synthetic route is introduced below. HPLC of Formula: C14H14O

General procedure: A mixture of 1 (2 mmol), 2 (4 or 15 mmol) and NaHSO4/SiO2 (2.1 mmol/g, 1.0 or 2.0g) in DCE (10 mL) was stirred at 80 C for 2 h, and then the used supported reagent was removed by filtration. The filtrate was evaporated to leave crude product, which was purified by column chromatography (hexane/chloroform) to obtain substituted chromans 3.

The synthetic route of 599-67-7 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Aoyama, Tadashi; Furukawa, Takuya; Hayakawa, Mamiko; Takido, Toshio; Kodomari, Mitsuo; Synlett; vol. 26; 13; (2015); p. 1875 – 1879;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts