Category: 597-31-9

Reference of 597-31-9, Adding some certain compound to certain chemical reactions, such as: 597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal,molecular formula is C5H10O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 597-31-9.

The hydrogenation feed as described in example 1 was used.Catalyst UsedThe catalyst described in example 1 was used, but 3¡Á3 mm pellets were produced.The catalyst comprised 55% of CuO and 45% by weight of Ak2O3, had a specific surface area (BET) of 95 m2/g, an Hg porosity of 0.38 ml/g and a tapped density of 1042 g/l.HydrogenationThe hydrogenation input was passed through the reactor in the downflow mode at an H2 pressure of 40 bar. The temperature in the upper half of the reactor was 96 C., and that in the lower half was 106 C. The WHSV was 0.37 kg of HPA/(kgcat*h). Together with the liquid input, about 110 mol % of H2 (based on methyolalkanals used) were metered in, corresponding to a hydrogen/starting material molar ratio of 1:1. Part of the hydrogenation output was mixed back into the input (recycle mode). The ratio of recycle to input was 16:1. A mean conversion of 95.9% at a mean pH of 8.3 was achieved over a number of days; Example 3 was repeated under the conditions indicated but the amount of hydrogen was doubled to a hydrogen/starting material molar ratio of 2.2 and the temperature was reduced to 93 C. in the upper half of the reactor and 103 C. in the lower half of the reactor. A mean conversion of 95.6% at a pH of 8.4 was achieved.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 597-31-9, 3-Hydroxy-2,2-dimethylpropanal, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; BASF Aktiengesellschaft; US2007/282135; (2007); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application of 597-31-9, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal, molecular formula is C5H10O2, molecular weight is 102.1317, as common compound, the synthetic route is as follows.

2,2-Dimethyl-3-hydroxypropionaldehyde (Hydroxypivalaldehyde, Mitsubishi Gas Chemical Co., Ltd., Purity 99.8%), 59.6 g of 2-ethyl-2-hydroxymethylpropane-1,3-diol (trimethylolpropane, Tokyo Chemical Industry Co., Ltd. reagent), 706 g of benzene, Granular Nafion (trade name “NR-50” Sigma Aldrich Reagent) 5.0 g in a 2-liter round bottom flask, Water generated under atmospheric pressure was withdrawn out of the system using a Dean-Stark trap while azeotropically boiling with benzene, The reaction was allowed to proceed until distillation of water stopped. This was filtered and recrystallized by concentration and cooling, To give crystals of 2- (5-ethyl-5-hydroxymethyl- [1,3] dioxan-2-yl) -2-methylpropan-1-ol.

The chemical industry reduces the impact on the environment during synthesis 597-31-9, I believe this compound will play a more active role in future production and life.

Reference:
Patent; Mitsubishi Gas Chemical Co., Ltd.; Ikeno, Kento; Yokobori, Umi; Sato, Hideyuki; Hasemi, Takashi; (26 pag.)JP2016/84286; (2016); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal. This compound has unique chemical properties. The synthetic route is as follows. Application In Synthesis of 3-Hydroxy-2,2-dimethylpropanal

Hydrogenation; The starting solution used was the mixture described above as hydrogenation feed. From 0 to 7% by weight (based on the hydrogenation feed) of a 15% by weight aqueous solution of trimethylamine (from 2 to 5% by weight (based on the hydrogenation feed), or of a 5% by weight aqueous solution of citric acid in the comparative examples) were added to this mixture in order to establish the particular pH of the hydrogenation effluent specified in Table 1. The hydrogenation feed thus obtained was pumped over the catalyst in a hydrogenation reactor with liquid circulation (circulation:feed=10:1) with a catalyst hourly space velocity of 0.4 kgHPA/Icat¡Áh in trickle mode at 40 bar and 120 C.A comparison of the process according to the invention with comparative examples V1 and V2, in which the pH of the hydrogenation effluent is in each case outside the inventive range, is shown by Table 1.For pH measurement, a Knick model 766 pH meter with a Schott N1041A glass electrode was used.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 597-31-9, 3-Hydroxy-2,2-dimethylpropanal.

Reference:
Patent; BASF SE; US2009/69604; (2009); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal, molecular formula is C5H10O2, molecular weight is 102.1317, as common compound, the synthetic route is as follows.Computed Properties of C5H10O2

EXAMPLE 2 (COMPARATIVE EXPERIMENT)Hydrogenation of the HPA-Comprising Stream from Example 1The HPA-comprising stream used was the mixture prepared according to example 1.This HPA-comprising stream was first passed into a hydrogenation reactor which was operated in trickle mode at H2 pressure 37-40 bar and at 100-120 C. The hourly space velocity was 0.28 kg of solution/(1 cat.*h). The catalyst used was a Cu/Al2O3 catalyst as described in EP-A-44444 or WO-A-2007/042456, which was activated according to the disclosure of EP-A-44444 or WO-A-2007/042456 in a tubular reactor at 190 C. at ambient pressure by passing a mixture of 5% by volume of hydrogen and 95% by volume of nitrogen (total volume 50 1 (STP)/h) over it for 24 h.The hydrogenation discharge was split into two substreams.In steady-state operation, one substream as the NPG-comprising circulation stream was combined with the HPA-comprising stream.The ratio of NPG-comprising circulation stream to the HPA-comprising stream from example 1 was approx. 10:1.The composition of the circulation stream was 25% by weight of water, 68% by weight of NPG, 1.6% by weight of HPA, remainder (approx. 6% by weight) other organic compounds.The hydrogenation feed thus obtained was subsequently introduced into the hydrogenation reactor.The composition of the hydrogenation feed was 25% by weight of water, 64% by weight of NPG, 7% by weight of HPA and 4% by weight of other organic compounds.The weight ratio of HPA to NPG in the hydrogenation feed was approx. 1:9.The portion of the hydrogenation discharge which was not recycled as the NPG-comprising circulation stream was conducted through a second hydrogenation reactor.The second hydrogenation reactor was operated at 37-40 bar and a temperature of 110-130 C. The catalyst used was the same catalyst as in the first hydrogenation reactor.A pH of approx. 8 was established in the discharge of the second reactor, by adding trimethylamine (TMA) (pH regulator) to the HPA-comprising stream from example 1.The pH regulator was supplied before the combination of the HPA-comprising stream with the NPG-comprising circulation stream.The temperature of the HPA-comprising stream from example 1 on supply of the pH regulator (TMA) was 80 C. The residence time between the addition of the pH regulator and the supply of the circulation stream was 10 minutes (>5 minutes).EXAMPLE 3 (INVENTIVE EXAMPLE)Hydrogenation of the HPA-Comprising Stream from Example 1The hydrogenation was effected under the same conditions as in example 2. To establish a pH of 8 at the outlet of the second reactor, the pH regulator (TMA) was, however, supplied directly to the NPG-comprising circulation stream before the NPG-comprising stream was combined with the HPA-comprising stream from example 1. The weight ratio of HPA to NPG in the hydrogenation feed obtained by combining these streams was approx. 1:9.The composition of the hydrogenation feed was 25% by weight of water, 64% by weight of NPG, 7% by weight of HPA and 4% by weight of other organic compounds.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,597-31-9, 3-Hydroxy-2,2-dimethylpropanal, and friends who are interested can also refer to it.

Reference:
Patent; BASF SE; US2011/282106; (2011); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal. This compound has unique chemical properties. The synthetic route is as follows. Application In Synthesis of 3-Hydroxy-2,2-dimethylpropanal

EXAMPLE 2Purification of HPA A complete mixture was prepared at 55C by adding 2505 parts of water into 835 parts of the crude HPA obtained in Reference Example 1. The mixture was gradually cooled from 55C to 32C over 5 h under stirring and then kept at 32C for one hour. The resultant crystals were separated by solid-liquid separation using a top-discharge centrifugal separator and then washed with water, to obtain HPA having a purity of 96.5% by weight in 60% recovery. The water content was 12% by weight and the remaining TEA content was 0.01% by weight. Synthesis of SPG from Purified HPA Into a solution of 95 parts of PE in 1200 parts of water, were added 5 parts of p-toluenesulfonic acid (PTSA) and 26 parts of SPG crystals obtained in Reference Example 2 as seed crystals (1.7% by weight of the total feed amount into the reaction system). Then, an aqueous solution of the purified HPA prepared by dissolving 160 parts of the purified HPA in 65 parts of water under heating at 80C was further added dropwise over 3.5 h. The SPG content X was 14.8% by weight. The pH of the reaction liquid at the initiation of reaction was 1.8, and the reaction temperature was 90C. After the dropwise addition, the reaction liquid was aged for 2 h while maintaining the temperature at 90C. The pH of the reaction production solution at the completion of reaction was 1.8. After the aging, the reaction product solution was separated into wet SPG and 1240 parts of reaction mother liquor by solid-liquid separation. The wet SPG was washed with 460 parts of water and then dried, to obtain 147 parts of SPG crystals. The yield of SPG was 56.8 mol% based on the charged PE, and the purity of SPG crystals was 99.9% by weight when analyzed by GC. The average particle size of SPG crystals was 23 um when measured on a water dispersion of SPG crystals by using a wet particle size distribution analyzer after exposing the water dispersion to ultrasonic wave for 10 min. The amount of waste water (reaction mother liquor + recovered washings + recovered water in drying) was 1780 parts. During the solid-liquid separation by filtration through a glass filter under reduced pressure, no crack occurred on the cake. The liquid content of SPG cake immediately after the filtration was 37% by weight. First Recycling Reaction Next, a first recycling reaction was performed in the same manner as in the above synthesis except for making 1200 parts of the reaction mother liquor (85% by weight of the whole amount) and 95 parts of PE into a solution under heating and using 0.7 part of PTSA and 240 parts of the aqueous solution of the purified HPA. The yield of dried SPG was 96.5 mol% and the purity was 99.8% by weight. The average particle size after exposed to ultrasonic wave was 22 um. During the solid-liquid separation by filtration through a glass filter under reduced pressure, no crack occurred on the cake. The liquid content of SPG cake immediately after the filtration was 37% by weight. Second Recycling Reaction Next, a second recycling reaction was performed in the same manner as in the first recycling reaction except for using 1100 parts of the reaction mother liquor (83% by weight of the whole amount) and 100 parts of water. The yield of dried SPG was 94.6 mol% and the purity was 99.8% by weight. The average particle size after exposed to ultrasonic wave was 22 um. During the solid-liquid separation by filtration through a glass filter under reduced pressure, no crack occurred on the cake. The liquid content of SPG cake immediately after the filtration was 37% by weight. Third and Subsequent Recycling Reactions The above procedure was repeated to perform the recycling reactions up to 10 cycles. The yield of SPG was 94.0 mol%, the purity was 99.7% by weight, and the particle size after exposed to ultrasonic wave was 20 um or more, each in average of third to tenth recycling reactions. The amount of waste water was 584 parts in average. During the solid-liquid separation by filtration through a glass filter under reduced pressure, no crack occurred on the cake. The liquid content of SPG cake immediately after the filtration was 42% by weight in average.

With the rapid development of chemical substances, we look forward to future research findings about 597-31-9.

Reference:
Patent; MITSUBISHI GAS CHEMICAL COMPANY, INC.; EP1598357; (2005); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Adding a certain compound to certain chemical reactions, such as: 597-31-9, 3-Hydroxy-2,2-dimethylpropanal, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 597-31-9, blongs to alcohols-buliding-blocks compound. 597-31-9

COMPARATIVE EXAMPLE 4 A suspension of 50 parts of PE in a mixture of 180 parts of water and 18 parts of xylene was heated to 60C, to which 124 parts of the crude HPA obtained in Reference Example 1 and 9 parts of a 50 wt % sulfuric acid were simultaneously added over 2 h. After stirring for 12 h while keeping the temperature at 60C, the mixture was neutralized with a 48 wt % sodium hydroxide aqueous solution. The resultant slurry mixture was filtered under reduced pressure and the separated solid was washed with water and dried, to obtain 99.5 parts of SPG. The yield was 89 mol%, the purity was 98% by weight, and the particle size after exposed to ultrasonic wave was 9 um. During the solid-liquid separation by filtration through a glass filter under reduced pressure, the crack of cake occurred. However, the filtration, washing with water and drying were made as in Example 1 to obtain SPG crystals. The liquid content of SPG cake immediately after the filtration was 60% by weight.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,597-31-9, its application will become more common.

Reference:
Patent; MITSUBISHI GAS CHEMICAL COMPANY, INC.; EP1598357; (2005); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal. A new synthetic method of this compound is introduced below., 597-31-9

Condensation cycle tower 3 Tower effluent with H2(Pressure 4.5 MPa) was fed to a hydrogenation reactor 5, the reactor was a tubular reactor, and the liquid was sprayed with hydrogen.The reactant is hydrogenated under the action of a copper-based catalyst to give the crude neopentyl glycol product, and the hydrogenation reactor 5 is maintained at a temperature of 160 to 170 C and a pressure of 4 MPa.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,597-31-9, 3-Hydroxy-2,2-dimethylpropanal, and friends who are interested can also refer to it.

Reference:
Patent; Shandong Hualu-Hengsheng Chemical Co., Lt; Chang, Huaichun; Hou, Zhiyang; Ren, Geyong; Wang, Zichang; Qiu, Xinzheng; Ren, Yuhuan; (10 pag.)CN103130611; (2016); B;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

597-31-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal, molecular formula is C5H10O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

Synthesis of 2,2-dimethyl-3-hydroxypropanal 73.6 g, 2-butyl-2-ethyl-1,3-propanediol 111.8 g, benzene 705g to particulate Nafion (trade name “NR-50”, Sigma-Aldrich put the Ltd.) 3.0 g round bottom flask 2L,while azeotroping with benzene produced water under normal pressure, allowed to react until distillation of water stopped and withdrawn out of the system using a Dean-Stark apparatuss. Filtration, concentrated by vacuum distillation, 2- (5-butyl-5-ethyl-1,3-dioxan-2-yl) -2-methylpropan-1-ol was obtained in a yield of 99%.

The chemical industry reduces the impact on the environment during synthesis 597-31-9, I believe this compound will play a more active role in future production and life.

Reference:
Patent; MITSUBISHI GAS CHEMICAL COMPANY INCORPORATED; IKENO, TAKETO; YOKOBORI, UMI; SATO, HIDEYUKI; TSUJIMOTO, TOMOO; (27 pag.)JP2016/13988; (2016); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

597-31-9, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal, molecular formula is C5H10O2, molecular weight is 102.1317, as common compound, the synthetic route is as follows.

The hydrogenation feed as described in example 1 was used.Catalyst UsedThe catalyst from example 1 was used.HydrogenationThe hydrogenation input was passed in the downflow mode at an H2 pressure of 37 bar through the reactor which was heated to 105 C. The WHSV was 0.32 kg of HPA/(kgcat*h). From 0 to 17% by weight (based on the hydrogenation feed) of a 50% strength by weight aqueous solution of trimethylamine were added to this mixture in order to set a pH of the hydrogenation output of greater than 8 (hydrogen/hydroxypivalaldehyde molar ratio: about 1.5). Part of the hydrogenation output was mixed back into the input (recycle mode). The ratio of recycle to input was 16:1. A mean conversion of 88.1% at a mean pH of 8.4 were achieved over a number of days.

Statistics shows that 597-31-9 is playing an increasingly important role. we look forward to future research findings about 3-Hydroxy-2,2-dimethylpropanal.

Reference:
Patent; BASF Aktiengesellschaft; US2007/282135; (2007); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts