Category: 59-23-4

Xu, Wei published the artcilePhysicochemical characterization of Gleditsia triacanthos galactomannan during deposition and maturation, Synthetic Route of 59-23-4, the main research area is Gleditsia maturation galactomannan rheol physiochem; Galactomannans; Gleditsia triacanthos; M/G ratio; Molecular weight; Viscosity.

Gleditsia triacanthos polysaccharide, known as galactomannan, has not been exploited as a new functional material even though it possesses industrial potential in food and biomedicine. Galactomannans were recovered from the endosperm of seeds (15 wk to 25 wk after flowering) for deposition and maturation anal. These galactomannans were characterized by using NMR (NMR), X-ray diffraction (XRD), and monosaccharide composition anal. (particularly the mannose to galactose ratio) and mol. weight, solubility, and rheol. measurements. The ratio of the three parts in mature seeds was as follows: endosperm (36.67%), hull (34.41%), and embryo (28.92%). The M/G ratio increased from 2.53 to 3.24 between 15 and 23 wk and then decreased to 3.16 in 25 wk, consistent with the trends of rheol. and solubility The mol. weight (1.28 × 106 g/mol) and intrinsic viscosity (882.53 mL/g) reached the maximum at 23 wk and then decreased. Addnl., NMR and XRD showed that the M/G ratio did not change the basic chem. structure but caused slight changes in crystallinity. The purpose of the study was to reveal the changes in galactomannan structure, rheol., and solubility during G. triacanthos galactomannan deposition and maturation to facilitate exploration of its potential industrial applications.

International Journal of Biological Macromolecules published new progress about Embryo, plant. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Synthetic Route of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fang, Chuchu published the artcileComparison on characterization and biological activities of Mentha haplocalyx polysaccharides at different solvent extractions, Computed Properties of 59-23-4, the main research area is Mentha polysaccharide antioxidant physicochem property; Biological activity; Mentha haplocalyx; Physicochemical property; Polysaccharide; Solvent extraction.

This study aimed to compare the effects of four solvent extractions on the physicochem. properties, antioxidant and hypoglycemic activities of polysaccharides from Mentha haplocalyx (MHPs). The solvent extractions included hot water, citric acid (pH 3.0), 5% NaOH/0.05% NaBH4 and 0.9% NaCl. Four corresponding MHPs named as MHP-W, MHP-C, MHP-A and MHP-S were obtained, resp. The exptl. results showed that the extraction yields, basic chem. components, monosaccharide contents, mol. weights, antioxidant and hypoglycemic activities of four MHPs were significantly different. However, their thermal stabilities, preliminary structural characteristics and monosaccharide types were similar. MHP-A possessed the highest extraction yield of 9.37 ± 0.24% and the smallest mol. weight MHP-W had the highest uronic acid content and the largest mol. weight More specifically, MHP-C exhibited the highest sugar content, the most remarkable antioxidant abilities of DPPH radical scavenging activity and ferric reducing power, and the strongest inhibitory activities on α-glucosidase and α-amylase. The above results indicated that MHP-C extracted with citric acid could be served as a promising bioactive substance for applications in the functional food and medicine industries.

International Journal of Biological Macromolecules published new progress about Food analysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Computed Properties of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Guo, Qingwen published the artcileHypoglycemic effects of polysaccharides from corn silk (Maydis stigma) and their beneficial roles via regulating the PI3K/Akt signaling pathway in L6 skeletal muscle myotubes, SDS of cas: 59-23-4, the main research area is Maydis stigma polysaccharide hypoglycemia alpha glucosidase skeletal muscle cell; Corn silk polysaccharides; Hypoglycemia; L6 myotubes; PI3K/Akt signaling pathway.

In the present study, the physicochem. properties of polysaccharides from corn silk (CSP) with different mol. weights were characterized and their inhibitory actions against α-glucosidase and α-amylase were evaluated. Then their effects on glucose uptake and mechanism of action in PI3K/Akt signaling pathway were also determined in L6 skeletal muscle cells. Results demonstrated that CSP could significantly inhibit a-amylase and a-glucosidase. CSP were non-toxic and they considerably increased the 2-NBDG uptake (P < 0.05) in L6 cells. Addnl., CSP regulated the PI3K/Akt signaling pathway and promoted the translocation of GLUT4 to the plasma membrane that would enhanced the glucose uptake in rat L6 skeletal muscle cells. Among the tested polysaccharides, CSP2 with the mol. weight of 62.16 kDa exerted appreciable hypoglycemic activity. Altogether it was suggested that CSP could be the promising candidate in the treatment of Type 2 Diabetes Mellitus (T2DM). The elucidation of the potential anti-diabetic mechanism of the polysaccharides from corn silk will facilitate their utilization in the functional food industries. International Journal of Biological Macromolecules published new progress about Cell membrane. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, SDS of cas: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Huo, Jiaying published the artcileImmunomodulatory activity of a novel polysaccharide extracted from Huangshui on THP-1 cells through NO production and increased IL-6 and TNF-α expression, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is polysaccharide Huangshui Moringa monosaccharide Escherichia; Baijiu; Huangshui; Immunomodulatory activity; Polysaccharide; Structural characterization.

Huangshui (HS), the byproduct of Chinese Baijiu, has attracted considerable attention due to its nutrient and microbial composition; however, none of the studies has explored the polysaccharides in HS yet. Here, from HS, we isolated a novel polysaccharide, HSP-3, with an average mol. weight of 26.40 kDa. The structure was elucidated based on monosaccharide composition and methylation anal., NMR, FT-IR, and AFM anal. It is mainly composed of mannose (46.6%), galactose (17.3%), arabinose (11.2%), glucose (10.5%), xylose (8.2%), fucose (5.2%), and rhamnose (1.0%). The backbone of HSP-3 was made up of → 2-β-D-Manp-(1 → 2,6)-β-D-Manp-1 → 6-β-D-Galp-(1 → 3,6)-β-D-Galp-(1 → 4)-α-L-Rhap-1 → 3,4-α-L-Rhap-1 → . Moreover, stimulation of the production of ROS, NO, TNF-α and IL-6, upregulation of the mRNA and protein expression levels of TNF-α and IL-6 in THP-1 cells, and enhanced the pinocytic and phagocytic capacities of THP-1 cells exhibited significant immunomodulatory properties of HSP-3. Altogether, this study suggests that HSP-3 could be used as an active component in functional foods.

Food Chemistry published new progress about Cell survival. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gan, Jiapan published the artcileMicrowave assisted extraction with three modifications on structural and functional properties of soluble dietary fibers from grapefruit peel, Synthetic Route of 59-23-4, the main research area is grapefruit peel soluble dietary fiber microwave assisted extraction.

Microwave-sodium hydroxide treatment (MST), microwave-enzymic treatment (MET) and microwave-ultrasonic treatment (MUT) were used to treat grapefruit peel, then the structural and functional properties of extracted soluble dietary fibers (SDF), named as MST-SDF, MET-SDF and MUT-SDF, were investigated. The SEM, mol. weight, X-ray diffraction, FT-IR, thermal properties and monosaccharide composition were used to determine the structural properties. Compared to the grapefruit peel SDF without treatment (WT-SDF) and pure microwave treatment (PMT-SDF), MST-SDF, MET-SDF and MUT-SDF showed a more complex and loose structure. Moreover, they possessed higher mol. weight, crystallinity and thermal stability, and more diverse monosaccharide composition In addition, functional properties, including water holding capacity (WHC), oil holding capacity (OHC), cholesterol adsorption capacity (CAC), glucose adsorption capacity (GAC) and nitrite ion adsorption capacity (NIAC), were enhanced by the three different modification methods. Especially, MUT-SDF showed the highest WHC, OHC, CAC, GAC and NIAC as compared with the other samples. In summary, the present study suggested that the MUT could be used as the ideal modification method for grapefruit peel SDF, and MUT-SDF has great potential for the application in functional food industry.

Food Hydrocolloids published new progress about Crystallinity. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Synthetic Route of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhou, Ting published the artcileCharacterization of polysaccharide structure in Citrus reticulate ′Chach′ peel during storage and their bioactivity, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Citrus polysaccharide arabinogalacturonan pectin storage; Glycosidic linkage; Immunomodulatory activity; Molecular weight; NMR; Pectin.

The peel of Citrus reticulate ′Chachiennsis′ (Chachi) is widely accepted as a functional food. It is generally recognized that its health benefits are dependent on storage time. However, the chems. responsible for this phenomonon remain unclear. As bioactive polysaccharides are dominant in Chachi, Chachi polysaccharides with various storage times (5-20 years) were prepared The monosaccharide composition was analyzed by GC-MS. NMR data revealed that Chachi polysaccharides were mainly consisted of arabinogalacturonan and another pectin with side chain of →4)-β-D-Galp-(1 → . α-L-Araf-(1→, →5)-α-L-Araf-(1→, →4)-α-D-GalpA-(1→, →4)-α-D-GalpAMe-(1→, →4)-β-D-Galp-(1→ and →4)-β-D-Glcp-(1→ were detected. The mol. weight of Chachi polysaccharides decreased along with the extension of storage time. However, the basic structure characteristics remained stable. The immumomodulatory activities of Chachi polysaccharides were improved as the storage time extended. The change of mol. weight was responsible for the improved immunomodulatory activity. The results explained how polysaccharides contributed to the enhanced health benefits of Chachi during storage.

Carbohydrate Research published new progress about Chinese medicine. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hosseini, Seyed Saeid published the artcileOptimization and characterization of pectin extracted from sour orange peel by ultrasound assisted method, HPLC of Formula: 59-23-4, the main research area is Citrus peel pectin ultrasound assisted method; Monosaccharide composition; Optimization; Pectin; Sour orange; Ultrasound.

In this work, a Box-Behnken design (BBD) with three variables (ultrasound power, irradiation time and pH) in three levels was applied for pectin extraction optimization. The optimization process showed that the maximum extraction yield was 28.07 ± 0.67% in ultrasound power of 150 W, irradiation time of 10 min and pH of 1.5 (as optimum conditions). In these conditions, ash, moisture and protein contents of SOPP were 1.89 ± 0.51, 8.81 ± 0.68 and 1.45 ± 0.23%, resp. HPLC anal. indicated that 65.3% of the extracted pectin was galacturonic acid and approx. 72% of total neutral sugars was galactose. The optimized pectin had a total phenolic content of 39.95 ± 3.13 mg gallic acid equivalent/g pectin, the surface tension of 46.56 ± 0.23 and 42.14 ± 0.61 mN/m in concentrations of 0.1 and 0.5%w/v, water holding capacity and oil holding capacity of 3.10 ± 0.12 and 1.32 ± 0.21 g water or oil/g pectin with a suitable emulsifying and antioxidant properties. In addition, SOPP with degree of esterification of 6.77 ± 0.43% was classified as low methoxyl pectin, which confirmed by FTIR and 1H NMR anal.

International Journal of Biological Macromolecules published new progress about Citrus aurantium. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lu, Yan published the artcileStructural characteristics and anticancer/antioxidant activities of a novel polysaccharide from Trichoderma kanganensis, Formula: C6H12O6, the main research area is Trichoderma kanganensis anticancer antioxidant polysaccharide structure; Anticancer activity; Antioxidant activity; Polysaccharide; Structural characteristics; Trichoderma kanganensis.

A novel water-soluble polysaccharide designated as TPS was isolated from the fermentation mycelia of Trichoderma kanganensis. TPS had a weight-average mol. mass of 3.074 × 105 Da, and the monosaccharide composition was consisted of Man (45.5%), GlcA (5.5%), Glc (10%), and Gal (39%). The major backbone of TPS was →6-α-D-Galp-1→5-β-D-Manf-1→5,6-β-D-Manf-1→5,6-β-D-Manf-1→, and the side chains are α-D-Glcp-1→4-α-D-Glcp-1→, β-D-Galf-1→, and α-D-Glcp-1→. In addition, we demonstrated that TPS was non-toxic in normal cells (LO2 cells) and inhibited the proliferation of mouse colon cells (CT26 cells). TPS also showed free radical scavenging activity against hydrogen peroxide. Overall, these results suggested that TPS from Trichoderma kanganensis may have potential application in biomedical fields.

Carbohydrate Polymers published new progress about Antitumor agents. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Oliveira, Ruberney S. published the artcileStructure elucidation of a bioactive fucomannogalactan from the edible mushroom Hypsizygus marmoreus, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is fucomannogalactan mushroom Hypsizygus structure antitumor; Antimelanoma; B16-F10 cell; Chemical structure; Fucomannogalactan; Hypsizygus marmoreus; Mushroom.

A fucomannogalactan (FMG-Hm), with a mol. weight of 17.1 kDa, obtained from fruiting bodies of Hypsizygus marmoreus exhibited promising in vitro antimelanoma effects. FMG-Hm was not cytotoxic, nor did it alter the cell morphol. and proliferation, but was able to inhibit colony-forming ability and cell migration in B16-F10 murine melanoma cells. An anal. of the monosaccharide composition indicated that FMG-Hm was composed of fucose, mannose, and galactose in a ratio of 1.00:1.08:3.17. The FMG-Hm was structurally characterized based on methylation anal., partial acid hydrolysis, and NMR experiments The results indicated that FMG-Hm contained a α-(1→6)-linked galactopyranosyl main chain, partially substituted at O-2 by non-reducing ends of α-L-fucopyranose and β-D-mannopyranose. The predicted structure of the heteropolysaccharide was established.

Carbohydrate Polymers published new progress about Antitumor agents. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Yi-yong published the artcileOptimization of microwave assisted extraction, chemical characterization and antitumor activities of polysaccharides from porphyra haitanensis, SDS of cas: 59-23-4, the main research area is microwave extraction antitumor polysaccharide porphyra; Antitumor; Chemical characterization; Microwave assisted extraction; Polysaccharides; Porphyra haitanensis.

Microwave assisted extraction (MAE) technol. was used to extract polysaccharides from Porphyra Haitanensis (PHP) with water. Polysaccharide yield was used as index to evaluate the extraction process. Effects of ratio of water to raw material (X1), microwave power (X2) and extraction time (X3) on polysaccharide yield were investigated. Based on single factor experiment, MAE process of PHP was optimized using response surface methodol. Chem. characterization of PHP was investigated based on anal. of chem. compositions, monosaccharide and thermal gravimetric. The antitumor activities of PHP in vivo and in vitro were evaluated. The results indicated that the optimal conditions for MAE of PHP were ratio of water to raw material 28.98(mL/g), microwave power 77.84 W and extraction time 14.14 min. MAE was a suitable and efficient technique for PHP extraction compared with traditional hot water extraction Anal. of chem. characterization showed that PHP contained 75.36 ± 1.48% of total carbohydrates, 24.63 ± 1.69% of uronic acid residue and no proteins with monosaccharides such as rhamnose, arabinose, xylose, mannose, glucose, and galactose in a molar ratio of 10.25:9.38:1:12.45:9.9:11.55. Thermal gravimetric anal. suggested that PHP was relatively stable below 170°C. PHP had obvious effect on inhibiting proliferation, inducing apoptosis of SGC-7901 tumor cells in vitro and antitumor effect on SGC-7901 tumor-bearing mice in vivo. The results suggested that PHP had the potential for clin. use in cancer prevention and treatment.

Carbohydrate Polymers published new progress about Antitumor agents. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, SDS of cas: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts