Category: 59-23-4

Chen, Ruizhan published the artcileUltrasonic disruption extraction, characterization and bioactivities of polysaccharides from wild Armillaria mellea, Formula: C6H12O6, the main research area is Armillaria polysaccharide splenocyte lymphocyte macrophage ultrasonic disruption extraction; Armillariamellea polysaccharides; Biological activities; Carbohydrate chemistry; Physicochemical properties.

An efficient ultrasonic disruption extraction (UDE) of polysaccharides from Armillariamellea (AM) were optimized by response surface methodol. (RSM). Under optimum conditions: ultrasonic power 915.00 W, temperature 69.27°C and time 39.13 min, the crude polysaccharides (AMPs) yield was 19.5%. Two purified fractions AMPs-1-1 and AMPs-2-1 were obtained through anion-exchange and gel chromatog. AMPs-1-1 was a heteropolysaccharide with average mol. weights of 1.23 × 105 Da, and composed of Glc, Gal and GlcA with mole percentages of 89.06%, 9.59% and 1.34%, resp., owning a backbone structure of (1→)-β-D-Glcp, (1 → 3,6)-α-D-Glcp and (1 → 3)-β-D-Glcp residues. AMPs-2-1 was a heteropolysaccharide with average mol. weights of 6.76 × 104 Da, and composed of Glc, Gal, GlcA and Man with mole percentages of 65.28%, 22.87%, 2.87% and 8.98%, containing a main backbone chain of (1 → 3,6)-α-D-Glcp and (1 → 6)-β-D-Glcp residues. AMPs-2-1 possessed obviously antioxidant activities in terms of stronger scavenging activity against DPPH· and ABTS+·, higher FRAP and ORAC value than AMPs-1-1. AMPs-2-1 could promote splenocyte lymphocytes and RAW264.7 macrophages proliferation and enhanced the phagocytosis of macrophages, exhibited significant immunomodulatory activities. These results suggested that UDE is an effective extract technol., and AMPs-2-1 could be explored as potential natural antioxidants and immunomodulatory agents.

International Journal of Biological Macromolecules published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xu, Yu published the artcileCharacterization, hypolipidemic and antioxidant activities of degraded polysaccharides from Ganoderma lucidum, Computed Properties of 59-23-4, the main research area is polysaccharide ganoderma lucidum hypolipidemic antioxidant activity; Antioxidant; Degradation; Ganoderma lucidum polysaccharides; Hypolipidemic.

The aim of this work is to characterize the primary structure and physicochem. properties of natural polysaccharides (GLP) and degraded polysaccharides (GLPUD) from Ganoderma lucidum, and evaluate their hypolipidemic and antioxidant activities. The results of particle size distribution and SEM (SEM) showed that Ganoderma lucidum polysaccharides were effectively degraded by ultrasonic method. GLPUD was composed of the same monosaccharide units as GLP but with different molar ratios. IR spectra and NMR showed that the primary structure of polysaccharides had not been changed by ultrasonic degradation Meanwhile, the thermal stability of polysaccharides increased after ultrasonic treatment. After administration by GLP and GLPUD four weeks, body weight, visceral index, atherosclerosis index (AI) and biochem. indicators in serum and in liver were determined The results showed that GLPUD had stronger hypolipidemic and antioxidant activities than GLP. GLPUD was more effective than the GLP for reducing AI, total cholesterol (TC), triglycerides (TG) and low-d. lipoprotein cholesterol (LDL-C), raising high d. lipoprotein (HDL-C) (p < 0.01), reducing malondialdehyde (MDA) content, as well as increasing the glutathione peroxidase (GSH-Px) in mice serum, increasing superoxide dismutase (SOD) activity and reducing MDA content in liver (p < 0.05 or p < 0.01). In addition, the histopathol. observations of mice livers showed that GLPUD could significantly improve lipid metabolism disorder in hepatocytes. Thus, GLPUD might be tested as a more effective hypolipidemic drug. International Journal of Biological Macromolecules published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Computed Properties of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gu, Jie published the artcileProcuring biologically active galactomannans from spent coffee ground (SCG) by autohydrolysis and enzymatic hydrolysis, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is galactomannan spent coffee ground autohydrolysis enzymic hydrolysis; Autohydrolysis; Biologically active; Enzymatic hydrolysis; Galactomannan; Spent coffee grounds.

Spent coffee grounds (SCG) are a promising raw material for galactomannan (GalM) production based upon its enrichment in galactomannan polysaccharides. In this work, SCG was pretreated by autohydrolysis for maximumly improving GalM extractability by endo-mannanase. The GalM in the prehydolyzate (GalM-PH) and enzymic hydrolyzate (GalM-EH) were obtained by ethanol precipitation and characterized. Under the optimized autohydrolysis conditions, 50.1% of GalM in pretreated SCG was converted into free GalM in enzymic hydrolyzate. Compositional anal. results revealed that GalM-PH was comprised of 81.7% galactomannan, higher than that of GalM-EH (76.4%). The mol. weight of GalM-PH and GalM-EH were 44.5 kDa and 28.0 kDa, resp. Antioxidant assays indicated that both GalM-EH and GalM-PH could scavenge 2,2-diphenyl-1-picryl-hydrazyl radicals and hydroxyl radicals. Immunol. and prebiotics anal. showed all GalM preparations exhibited pronounced activities for proliferating the probiotics and proliferating the Macrophages cell for NO production, in which the GalM-EH outperformed the GalM-PH. These results imply that the GalM extracted from SCG are the bioactive substances that can be used as antioxidant, prebiotics, and immunostimulants.

International Journal of Biological Macromolecules published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Florez-Fernandez, Noelia published the artcileRecovery of bioactive and gelling extracts from edible brown seaweed Laminaria ochroleuca by non-isothermal autohydrolysis, Related Products of alcohols-buliding-blocks, the main research area is bioactive gelling extract Laminaria seaweed isothermal autohydrolysis; Alginate; Antioxidant; Autohydrolysis; Cytotoxicity; Fucoidan; Laminaria ochroleuca.

The non-isothermal autohydrolysis temperature impact of edible brown seaweed Laminaria ochroleuca was studied to recover high valuable compounds Extraction yield was determined, above 80% was obtained at 220 °C. The maximal fucose content (17% d.b.) was attained at 180 °C, whereas the maximal sulfate was achieved at 160 °C, and phenolic and protein content at 220 °C. The maximum sulfated fucoidan content (41.38 g fucoidan/100 g extract) was obtained at 160 °C, whereas the maximum fucose oligosaccharides was obtained at 180 °C. The antioxidant capacity was equivalent to 32 mg Trolox/g dry extract produced at 220 °C. The milder processing condition was selected to study the potentiality of the precipitated alginate in terms of viscoelastic properties determined by rheol. Alginate extraction (14.94 g/100 g extract) was determined at 160 °C. The crude fucoidan fractions were tested at 25-500 μg/mL, showed up to 50% cell growth inhibition in four selected tumoral cell lines.

Food Chemistry published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fu, Yuan published the artcilePolysaccharides from loquat (Eriobotrya japonica) leaves: Impacts of extraction methods on their physicochemical characteristics and biological activities, Application In Synthesis of 59-23-4, the main research area is Eriobotrya polysaccharide extraction method physicochem characteristics biol activity; Bioactivity; Chemical structure; Extraction method; Loquat; Polysaccharide.

Impacts of hot water extraction (HWE), pressurized water extraction (PWE), high-speed shearing homogenization extraction, microwave assisted extraction (MAE), ultrasound assisted extraction (UAE), ultrasound assisted enzymic extraction, and ultrasound-microwave assisted extraction (UMAE) on physicochem. characteristics and bioactivities of polysaccharides from loquat (Eriobotrya japonica) leaves (LLPs) were investigated. Results showed that the degrees of esterification, contents of phenolics and uronic acids, constituent monosaccharides, apparent viscosities, and mol. weights of LLPs varied by different extraction methods. Bioactivities of LLPs were also significantly affected by different extraction methods. The high mol. weight and high degree of esterification of LLP-W and LLP-P extracted by HWE and PWE, resp., might contribute to their strong binding capacities. The strong antioxidant activities and inhibitory effects on α-amylase and α-glucosidase were found in LLP-M and LLP-U extracted by MAE and UAE, resp., which might be attributed to their contents of uronic acids, contents of total phenolics, and mol. weights The low mol. weights and viscosities of LLP-U and LLP-UM extracted by UMAE might contribute to their strong prebiotic effects. These findings could provide scientific foundations for selecting appropriate extraction methods to obtain LLPs with desired bioactivities for applications in the pharmaceutical and functional food industries.

International Journal of Biological Macromolecules published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kong, Qiuhong published the artcileIn vitro fermentation characteristics of polysaccharide from Sargassum fusiforme and its modulation effects on gut microbiota, Synthetic Route of 59-23-4, the main research area is polysaccharide Sargassum fusiforme fermentation gut microbiota; Fermentation; Gut microbiota; Sargassum fusiforme polysaccharide (SFP); Short chain fatty acids (SCFAs); Structural characteristics.

In this study, polysaccharides from Sargassum fusiforme (SFP) were obtained by cellulase assisted hot water extraction The chem. composition, structural characteristics, and in vitro fermentation properties of SFP were investigated. Results showed that the contents of total carbohydrate, protein, uronic acid and sulfate in SFP were 83.25%, 1.42%, 12.80% and 7.81%, resp. It mainly consisted of fucose glucose and galactose, with mol. weight of 255.83 kDa. UV spectrum, FTIR, SEM and AFM results showed that SFP was a typical sulfate polysaccharide with relative smooth surface and regular shape. After in vitro fermentation for 24 h, the pH value of fermentation medium declined significantly (p < 0.05), utilization of carbohydrate was 53.17%. The contents of total SCFAs increased by 10.77 times. Moreover, SFP fermentation could change obviously the microbiota composition It significantly increased the abundance of Faecalibacterium (increased by 49.07% compared with the Blank24 group), Phascolarctobacterium (increased by 88.06%), Bifidobacterium (increased by 139.13%), Ruminococcaceae_UCG-014 (increased by 177.78%), and Lactobacillus (increased by 400.00%), decreased the abundance of Prevotella_9 (decreased by 34.54%) and Blautia (decreased by 40.79%) at genus level. These results showed that SFP could be utilized by microbiota in human feces, and may have the potential to improve intestinal health. Food and Chemical Toxicology published new progress about Agathobacter. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Synthetic Route of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Yaping published the artcileCharacterization of a polysaccharide with antioxidant and anti-cervical cancer potentials from the corn silk cultivated in Jilin province, Quality Control of 59-23-4, the main research area is corn silk polysaccharide anticervical cancer antioxidant activity; Anti-cervical cancer; Antioxidant; Characterization; Corn silk; Polysaccharides.

Corn silk polysaccharides (CSPs) were extracted from the corn silk cultivated in Jilin province, China, where is one of the golden corn belts worldwide. Three fractions (CSP-1, CSP-2 and CSP-3) were obtained by DEAE-52 cellulose and the former two fractions were further purified by Sephadex G-150 column chromatog. to obtain CSP-S-1 and CSP-S-2. The mol. weights of CSP-S-1 and CSP-S-2 were calculated to be 586 kDa and 813 kDa, resp. CSP-S-1 was composed of galactose, arabinose, xylose and rhamnose at a molar ratio of 4.16:1.00:1.01:6.32 and CSP-S-2 was composed of galactose, arabinose, glucose and rhamnose at a molar ratio of 8.71:3.58:0.169:1.00. CSP-S-2 outperformed CSP-S-1 in scavenging DPPH, ABTS and hydroxyl radicals, and significantly inhibited the proliferation of HeLa cells. IR and NMR anal. indicated that CSP-S-2 was pyranose. CSP-S-2 consisted of 1 → 4 and 1 → 6 linkages and exhibited a triple helix configuration. In summary, CSP-S-2 possesses high potential to be developed as a novel antioxidant and anti-cervical cancer agent.

International Journal of Biological Macromolecules published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Quality Control of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Chen published the artcileOptimation for preparation of oligosaccharides from flaxseed gum and evaluation of antioxidant and antitumor activities in vitro, Application In Synthesis of 59-23-4, the main research area is flaxseed gum oligosaccharide antioxidant antitumor activity; Antioxidant activity; Antitumor activity; Flaxseed polysaccharides; Oligosaccharides preparation.

Flaxseed oligosaccharides (FGOS) were prepared by degradation of flaxseed gum (FG) using enzymic method. Factors affecting the enzymic hydrolysis of FG were investigated by single factor and orthogonal tests. In the optimum hydrolysis conditions (reaction time 12 h, temperature 50°C, pH 4.5, cellulase concentration 100 U/mL), the reducing sugar ratio and extraction yield of FGOS were 33.6 ± 0.35% and 56.8 ± 0.41%, resp. The average mol. weight of FGOS was about 1.6 kDa, which consists of mannose, galactose, glucose, arabinose, glucuronic acid, xylose, rhamnose, ribose, galacturonic acid. Fourier-transform IR spectra and NMR indicated that FG was successfully degraded to FGOS. FGOS exhibited better antioxidant activities than FG on scavenging hydroxyl, ABTS and DPPH radicals. In vitro cytotoxicities experiments reveal FGOS acquire the ability of antiproliferation against HepG2 and Hela cells in a dose-dependent manner.

International Journal of Biological Macromolecules published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xue, Zihan published the artcileStructure, thermal and rheological properties of different soluble dietary fiber fractions from mushroom Lentinula edodes (Berk.) Pegler residues, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Lentinula soluble dietary fiber fraction structure thermal rheol property.

Four soluble dietary fiber subfractions were obtained via stepwise ethanol precipitation from Lentinula edodes byproducts (LESDF). The mol. weight distributions of these four LESDF subfractions were 6.43 × 107 Da, 6.25 × 106 Da, 1.58 × 105 Da and 2.50 × 104 Da, resp., and they exhibited different surface morphol. properties, particle size distribution, ζ-potential and apparent viscosity. Different structural features of LESDF subfractions were analyzed through monosaccharide composition, FT-IR, periodate oxidation and smith degradations These characteristics affected their thermal (TGA-DSC) properties and the rheol. properties of LESDF-containing doughs. Results indicated that the higher the mol. weight of LESDF products, the greater the loss of dietary fiber weight by degradation Meanwhile, LESDF-3 exhibited the most rheol. benefits and the possible repeating unit were investigated by 1D/2D NMR. It was found that addition of LESDF with medium mol. weight and high branching degree played an important role in improving dough elasticity.

Food Hydrocolloids published new progress about Dietary fiber. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jia, Mengyun published the artcileStructural characteristics and functional properties of soluble dietary fiber from defatted rice bran obtained through Trichoderma viride fermentation, Application of (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Trichoderma fermentation soluble dietary fiber defatted rice bran.

Trichoderma viride was utilized to ferment the defatted rice bran (DRB), and soluble dietary fiber was prepared before and after fermentation, named as B-SDF and F-SDF, resp. Optimum fermentation conditions for yield of F-SDF were determined using response surface methodol. (RSM). The yield of F-SDF was significantly increased from 10.5 (weight/weight, %) to 33.4 (weight/weight, %) under the optimal conditions (inoculum size = 10%, pH = 5.8 and time = 41 h). Fourier transform IR spectroscopy (FTIR) demonstrated that both B-SDF and F-SDF had typical characteristics of the IR spectrum of polysaccharides, and X-ray diffraction (XRD) revealed they were mainly substances of amorphous structure. In addition, F-SDF showed looser structure by SEM (SEM) anal., increased mol. weight by high-performance gel permeation chromatog. (HPGPC) anal., and more complex monosaccharide composition by high-performance anion exchange chromatog. (HPAEC) anal. Furthermore, functional properties anal. showed that F-SDF exhibited higher water-holding capacity (WHC), oil-holding capacity (OHC), water solubility (WS) and cholesterol absorption capacity (CAC) than B-SDF. In summary, the present study suggested that SDF from defatted rice bran obtained through Trichoderma viride fermentation has a higher potential to be used as a functional ingredient in foods.

Food Hydrocolloids published new progress about Dietary fiber. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application of (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts