Category: 584-02-1

Malathi, R. published the artcileStudy on preliminary phytochemicals and GC-MS analysis of Justicia adhatoda leaves extract, Name: 3-Pentanol, the main research area is Justicia leaf root bark alkaloid flavonoid glycoside coumarin tannin.

Several natural products have been implemented as an alternative health care treatment and in discovery of effective modern drugs. A major focus of natural product chem. has been toward drug design and discovery. Justicia adhatoda is a well-known Indian medicinal plant valued for its pharmacopeia. This plant root, bark, leaf and flower are used to heal several diseases and poisonous bites. The present work was to evaluate the phytochems. and GC-MS anal. of J. adhatoda leaves extracts The extracts were subjected to qual. phytochem. screening using standard procedures. The result showed that the phytochems. present in the extract of J.adhatoda are alkaloids, flavonoids, glycosides, cardiac glycosides, coumarins, hydroxy anthraquinones, tannins, phlobatannins, proteins, xantho protein, steroids and phenols. The GC-MS anal. of acetone extract showed the presence of many secondary metabolites like phytol (0.8%), 9,12,15-octadecatrienoic acid, (Z,Z,Z) (1.6%), butane, 2,2-di-Me (0.21%), pentane, 2,3,3-tri-Me (0.22%), hexathiane (0.08%), and benzenesulfonic acid (0.22%). The diversity of phytochem. present in the plant suggests that J. adhatoda could serve as a source of useful drugs

Journal of Drug Delivery and Therapeutics published new progress about Amino acids Role: PAC (Pharmacological Activity), THU (Therapeutic Use), BIOL (Biological Study), USES (Uses). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Name: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhou, Jiadi published the artcileSelf-photocatalyzed regulable alkylation of 2H-benzothiazoles with diverse aliphatic C-H donors, Quality Control of 584-02-1, the main research area is benzothiazole alc photochem alkylation; alkyl hydroxy benzothiazole preparation; amide benzothiazole photochem alkylation; amido alkyl benzothiazole preparation; alc benzothiazole photochem alkylation; alkylbenzothiazole preparation.

Here, a mild and efficient method that combines self-photoredox catalysis and hydrogen atom transfer to achieve the alkylation of 2H-benzothiazoles with alcs., ethers, lactams, amides and alkane, which features broad substrate scope and excellent functional group compatibility was reported. Notably, alcs. can be used not only as hydroxyalkylating reagents, but also as dehydroxyalkylating reagents in this regulable alkylation protocol. The previous elusive self-photocatalytic mechanism was investigated and preliminary results on this catalytic alkylation were reported.

Green Chemistry published new progress about Alkanes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Quality Control of 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Fang published the artcileDirect Benzylic C(sp3)-O Coupling with Alcohol via Site-Selective C(sp3)-H Cleavage at Room Temperature through a Remote Directing Group-Enabled Radical Relay Strategy, Quality Control of 584-02-1, the main research area is benzylic carbon oxygen coupling alc regioselective copper catalyst; alkyl aryl carbamate carbon hydrogen bond cleavage.

Employing a low loading of the terminal oxidant, a remote directing group-enabled radical relay strategy for benzylic direct C(sp3)-H alkoxylation with alcs. at room temperature is developed. Satisfactory site-selectivity, chemoselectivity, and reaction scope are achieved under simple and mild conditions, and no ligand or additive is required. Mechanistic studies, ready conversions of the directing group, and other benzylic functionalizations currently under development in laboratory further indicate the promising potentials of this remote directing group-enabled radical relay strategy.

Journal of Organic Chemistry published new progress about Alkoxylation. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Quality Control of 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gao, Han published the artcileTransition Metal-Free Radical α-Oxy C-H Cyclobutylation via Photoinduced Hydrogen Atom Transfer, Recommanded Product: 3-Pentanol, the main research area is oxyalkane arylsulfonyl bicyclobutane regioselective quinuclidine photocatalyst ring opening; arylsulfonyl cyclobutane preparation.

A transition-metal-free photoinduced radical-mediated α-oxy C-H cyclobutylation reaction of bicyclo[1.1.0]butane (BCB) compounds was described. In this protocol, α-oxy C(sp3)-H motifs including ethers and alcs. were activated via photocatalytic conditions, releasing the ring strain of BCBs and generating 1,3-disubstituted cyclobutanes in 40-80% yields. Control experiments and Stern-Volmer quenching experiments indicated that the reaction proceeded through the generation of α-oxy carbon-centered radical intermediates by photoinduced hydrogen atom transfer (HAT) process.

Advanced Synthesis & Catalysis published new progress about Aromatic compounds, sulfones Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Recommanded Product: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sadier, Achraf published the artcileEffect of carbon chain length on catalytic C-O bond cleavage of polyols over Rh-ReOx/ZrO2 in aqueous phase, Formula: C5H12O, the main research area is polyol carbon oxygen bond cleavage rhenium rhodium bimetallic catalyst.

Production of linear deoxygenated C4 (butanetriols, -diols, and butanols), C5 (pentanetetraols, -triols, -diols, and pentanols), and C6 products (hexanepentaols, -tetraols, -triols, -diols, and hexanols) is achievable by hydrogenolysis of erythritol, xylitol, and sorbitol over supported-bimetallic Rh-ReOx (Re/Rh molar ratio 0.5) catalyst, resp. After validation of the anal. methodol., the effect of some reaction parameters was studied. In addition to C-O bond cleavage by hydrogenolysis, these polyols can undergo parallel reactions such as epimerization, cyclic dehydration, and C-C bond cleavage. The time courses of each family of linear deoxygenated C4, C5, and C6 products confirmed that the sequence of appearance of the different categories of deoxygenated products followed a multiple sequential deoxygenation pathway. The highest selectivity to a mixture of linear deoxygenated C4, C5, and C6 products at 80% conversion was favored under high pressure in the presence of 3.7wt.%Rh-3.5wt.%ReOx/ZrO2 catalysts (54-71% under 80 bar) at 200 °C.

Applied Catalysis, A: General published new progress about C-O bond cleavage (catalysts). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Formula: C5H12O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pardatscher, Lorenz published the artcileHighly Efficient Abnormal NHC Ruthenium Catalyst for Oppenauer-Type Oxidation and Transfer Hydrogenation Reactions, SDS of cas: 584-02-1, the main research area is cationic ruthenium phosphinoethylimidazolylidene carbene complex preparation catalyst transfer hydrogenation; crystal structure cationic ruthenium phosphinoethylimidazolylidene carbene complex; mol structure cationic ruthenium phosphinoethylimidazolylidene carbene complex; oxidation catalyst cationic ruthenium phosphinoethylimidazolylidene carbene complex.

The Ru complex [Ru(OAc)(a-PC)2]Br (3) containing two abnormal NHC ligands was obtained by reaction of Ru(OAc)2(PPh3)2 (1) with 1-(2-diphenylphosphinoethyl)-3-mesitylimidazolium bromide in the presence of NaOAc. Complex 3 catalyzes the Oppenauer-type oxidation of a number of alcs. at unrivalled reaction rates reaching TOFs up to 550,000 h-1, at low catalyst loadings (S/C >10,000) and using acetone in stoichiometric amounts Complex 3 is also highly active in the reverse transfer hydrogenation of several ketones with iso-PrOH, displaying TOFs up to 600,000 h-1.

ACS Catalysis published new progress about Crystal structure. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, SDS of cas: 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Balthazar, Celso F. published the artcileEffect of probiotic Minas Frescal cheese on the volatile compounds profile and metabolic profile assessed by nuclear magnetic resonance spectroscopy and chemometric tools, Application of 3-Pentanol, the main research area is cheese probiotics volatile compound metabolic profile NMR spectroscopy chemometrics; Lacticaseibacillus casei 01; amino acid; chemometrics; fresh cheese; probiotic.

This study aimed to evaluate the effect of Lacticaseibacillus casei 01 as a probiotic culture on the production of volatile organic compounds and metabolic profile of Minas Frescal cheese. Lactose (α-lactose and β-lactose), fatty acids (unsaturated and saturated), citric acid, tryptophan, and benzoic acid were the main compounds Compared with the control cheese, probiotic cheese was characterized by the highest concentration of tryptophan and presented a higher number of volatile acids. The control cheese was characterized by the highest concentration of benzoic acid and fatty acids, resulting in a higher number of volatile alcs. and esters. No differences were observed for α-lactose, β-lactose, and citric acid contents. A clear separation of probiotic and control Minas Frescal cheese was obtained using 1H NMR spectra, demonstrating that the addition of probiotic culture altered the metabolic profile of Minas Frescal cheese. Overall, the findings suggested that the addition of probiotic culture promoted the proteolysis in the fresh cheeses, decreased the lipolysis, and altered the volatile compounds Furthermore, NMR spectroscopy coupled to chemometrics tools could be used to differentiate probiotic and conventional cheeses.

Journal of Dairy Science published new progress about Alcohols Role: ANT (Analyte), FFD (Food or Feed Use), ANST (Analytical Study), BIOL (Biological Study), USES (Uses). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Application of 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Thiyagarajan, Subramanian published the artcileRuthenium-Catalyzed α-Alkylation of Ketones Using Secondary Alcohols to β-Disubstituted Ketones, Application In Synthesis of 584-02-1, the main research area is Ruthenium pincer catalyzed alkylation ketone secondary alc.

An assortment of aromatic ketones was successfully functionalized with a variety of unactivated secondary alcs. that serve as alkylating agents, providing β-disubstituted ketone products in good to excellent yields. Remarkably, challenging substrates such as simple acetophenone derivatives are effectively alkylated under this ruthenium catalysis. The substituted cyclohexanol compounds displayed product-induced diastereoselectivity. Mechanistic studies indicate the involvement of the hydrogen-borrowing pathway in these alkylation reactions. Notably, this selective and catalytic C-C bond-forming reaction requires only a minimal load of catalyst and base and produces H2O as the only byproduct, making this protocol attractive and environmentally benign.

Organic Letters published new progress about Alkylation catalysts. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Application In Synthesis of 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Srinivasan, Anbalagan published the artcileGC-MS investigations of VOCs in South Indian honey samples as environmental biomarkers, HPLC of Formula: 584-02-1, the main research area is volatile organic compound honey biomarker gas chromatog mass spectrometry; Aroma profile; Carboxylic acids; Honey; Liquid–liquid extraction; Volatile organic compounds.

Natural honey is a viscous liquid composed of a supersaturated solution of glucose and fructose. Honeybees collect nectar and convert them into honey through biochem. reactions. These small creatures are the major contributors to pollination and food production for humans. At the same time, they are the worst victims of urbanization and irrational use of pesticides, insecticides, and other hazardous materials. Any disturbance to the existence of honeybees is a serious threat to the biodiversity. The quality of a honey sample is largely affected by the contamination of volatile organic compounds (VOCs) due to environmental pollution. The present study analyzes systemically 25 samples of honey harvested from the southern part of the Western Ghats for the probable existence of traces of toxic substances. The samples were subjected to a liquid-liquid extraction process, followed by gas chromatog.-mass spectrometry (GC-MS) to identify and characterize the hazardous substances/volatile organic compounds The results show the presence of nearly 540 VOCs and semi-VOCs comprising alcs., carboxylic acids, halogenated hydrocarbons, furan and pyran derivatives, and pyridine and pyrazine derivatives Malonic acid (0.01-0.18%), n-hexa decanoic acid (0.02-8.69%), 9-octa decanoic acid (0.03-4.01%), propanoic acid (1.01%), oleic acid (6.15%), and benzoic acid (1.48%) were found to be present in some of the samples. This investigation would pave the way to identifying the geog. location of floral honey based on the specific VOCs present in the samples.

Environmental Monitoring and Assessment published new progress about Aldehydes Role: ANT (Analyte), BSU (Biological Study, Unclassified), ANST (Analytical Study), BIOL (Biological Study). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, HPLC of Formula: 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zribi, I. published the artcileGC-MS analysis of the volatile profile and the essential oil compositions of Tunisian Borago Officinalis L.: Regional locality and organ dependency, Name: 3-Pentanol, the main research area is Borago officinalis essential oil oxygenated monoterpene sesquiterpene GC MS.

Seeking to explore new local natural resources, volatile profile as well as essential oil compositions of Tunisian Borago officinalis L. were analyzed. The current study aims at investigating the effects of the geog. origin and the plant part (flowers, leaves, and rosettes leaves) on the volatile profile of Borago officinalis L. The aerial parts were collected from three bioclimate zones in Tunisia namely Tunis, Bizerte, and Zaghouan. The essential oils were extracted by hydro distillation The chem. composition of the latter was determined by gas chromatog. coupled to mass spectrometry. Furthermore, an exptl. procedure combining solid phase microextraction and gas chromatog. coupled to mass spectrometry was implemented to study the volatile profile of Borago officinalis L. It was set up to assess the influence of different plant organs obtained from various sites on the aromatic profile. Essential oil yields ranged from 0.14 ± 0.00% to 0.18 ± 0.01%. Benzenacetaldehyde was the major compound of the essential oils (7.11-9.16%). Chromatog. anal. revealed that the chem. compositions vary considerably from one region to another. The ones extracted from Bizerte and Zaghouan collections were characterized by the predominance of aldehydes (27.02% and 35.16%), followed by oxygenated monoterpenes (20.64% and 20.58%). The essential oils obtained from the third collection (Tunis) showed the predominance of oxygenated monoterpenes (27.23%), followed by aldehydes (23.93%) and oxygenated sesquiterpenes (12.22%). The aldehydes were identified as the major chem. class in the flowers volatile compounds dominated by octanal (13.32-16.42%) as well as in the leaves where nonanal was the major one (10.49-11.55%). In the rosettes aromatic profile, the oxygenated monoterpenes were the main chem. class with a percentage ranging from 39.45 to 46.64%. A relatively high content of acids (10.15%) was exclusively determined in Zaghouan flowers volatile profile. Principal Component Analyses and Hierarchical Clustering Analyses were pertinent tools to differentiate the volatile fractions. The findings showed a remarkable difference and significant variations in quality and quantity of the secondary metabolites.

Industrial Crops and Products published new progress about Aldehydes Role: ANT (Analyte), BSU (Biological Study, Unclassified), ANST (Analytical Study), BIOL (Biological Study). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Name: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts