Category: 584-02-1

Xia, Guoqin published the artcileReversing conventional site-selectivity in C(sp3)-H bond activation, SDS of cas: 584-02-1, the main research area is directing group regioselective carbon hydrogen bond activation.

One of the core barriers to developing C-H activation reactions is the ability to distinguish between multiple C-H bonds that are nearly identical in terms of electronic properties and bond strengths. Through recognition of distance and mol. geometry, remote C(sp2)-H bonds have been selectively activated in the presence of proximate ones. Yet achieving such unconventional site selectivity with C(sp3)-H bonds remains a paramount challenge. Here we report a combination of a simple pyruvic acid-derived directing group and a 2-pyridone ligand that enables the preferential activation of the distal γ-C(sp3)-H bond over the proximate β-C(sp3)-H bonds for a wide range of alc.-derived substrates [e.g., I + Me 4-iodobenzoate → II (52%, + 23% diarylated, after esterification)]. A competition experiment between the five- and six-membered cyclopalladation step, as well as kinetic experiments, demonstrate the feasibility of using geometric strain to reverse the conventional site selectivity in C(sp3)-H activation.

Nature Chemistry published new progress about Aryl iodides Role: RCT (Reactant), RACT (Reactant or Reagent). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, SDS of cas: 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jia, Hong-xin published the artcileThe stability of milk-based infant formulas during accelerated storage, Quality Control of 584-02-1, the main research area is milk infant formula fatty acid food storage.

The stability of milk-based formulas (infant formula and follow-up formula) were evaluated at 42°C and 50°C, during 90 days. Unsaturated fatty acids, color, peroxide values, headspace oxygen and volatile organic compounds (VOCs) were analyzed to evaluate the stability of milk-based formulas. No significant changes were observed in the unsaturated fatty acids (except DHA with a significant decrease after 90 days storage) of milk-based formulas stored at 42 or 50°C for 90 days. There is a significant change in color of the formulas during storage. For peroxide values and headspace oxygen, samples which were stored at a higher temperature would have higher peroxide values and less headspace oxygen after 90 days. For VOCs, results showed the significant differences of VOCs profiles in the formulas stored at different temperatures and lengths of storage period. In this study, the higher fat, the less oxidation stability was found.

CyTA–Journal of Food published new progress about Food storage. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Quality Control of 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Manzocchi, E. published the artcileFeeding cows with hay, silage, or fresh herbage on pasture or indoors affects sensory properties and chemical composition of milk and cheese, Related Products of alcohols-buliding-blocks, the main research area is milk cheese feeding cow silage herbage indoor sensory property; cheese sensory profile; dairy cow; herbage utilization method; milk sensory profile.

In European countries, silage-free feeding is an ancient tradition and has a particularly pos. reputation among consumers. In the present study, we compared grass-based forages from the same plot conserved as hay or silage or fed fresh either on pasture or indoors, and we evaluated the differences in sensory properties of milk and uncooked pressed cheese. All herbage from the first cut of a grassland dominated by perennial ryegrass was harvested on the same day and preserved either as hay or silage. The first regrowth of the same plot was used for strip grazing or green feeding indoors. Balanced by breed, 24 Montbeliarde and 24 Holstein cows were allocated to the 4 treatments. Apart from the forages, the late-lactation cows received 3 kg/d of dry matter from concentrate After 2 wk of dietary adaptation, the bulk milk of 3 subgroups, each with 4 cows, was collected. Part of the milk was pasteurized, and part was left raw and partly transformed to small-sized Cantal-type cheese ripened for 9 wk. Milk and cheese underwent descriptive sensory anal. by a trained sensory panel, as well as analyses of physicochem. traits. Volatile organic compounds of the cheeses were also analyzed. Raw and pasteurized milk from hay-fed cows had less intense odors of cooked milk, cream, and barnyard than milk from grazing cows, whereby the effect of pasteurization did not differ between herbage utilization methods. Cheeses obtained from cows fed fresh herbage (grazing and indoors) were clearly yellower than cheeses from silage- and hay-fed cows, which coincided with the color intensity perceived by the panelists. Moreover, cheeses from cows fed fresh herbage had more intense barnyard and dry fruit flavors, were perceived as creamier and having less lactic odor, and exhibited more fat exudation than those from cows fed conserved herbage. Only a few differences were observed in milk and cheeses from hay-fed compared with silage-fed cows, and those differences were far less pronounced than those of milk and cheeses from cows fed fresh herbage. In conclusion, the present study did not substantiate assumptions of clear sensory differences of milk and uncooked pressed cheese from hay-fed compared with silage-fed cows. For the first time, this study reports that the global flavor intensity of cheeses from indoor green-fed cows is similar to that of cheeses derived from cows fed conserved forages, whereas cheeses from grazing cows have the greatest global flavor intensity.

Journal of Dairy Science published new progress about Agrostis idahoensis. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Weber, Stefan published the artcileManganese-Catalyzed Hydrogenation of Ketones under Mild and Base-free Conditions, Related Products of alcohols-buliding-blocks, the main research area is diphosphine alkyl manganese carbonyl catalyzed hydrogenation ketone mild base; alpha beta unsaturated carbonyl reduction diphosphine alkyl manganese carbonyl.

In this paper, several Mn(I) complexes were applied as catalysts for the homogeneous hydrogenation of ketones. The most active precatalyst is the bench-stable alkyl bisphosphine Mn(I) complex fac-[Mn(dippe)(CO)3(CH2CH2CH3)]. The reaction proceeds at room temperature under base-free conditions with a catalyst loading of 3 mol % and a hydrogen pressure of 10 bar. A temperature-dependent selectivity for the reduction of α,β-unsaturated carbonyls was observed At room temperature, the carbonyl group was selectively hydrogenated, while the C:C bond stayed intact. At 60°, fully saturated systems were obtained. A plausible mechanism based on DFT calculations which involves an inner-sphere hydride transfer is proposed.

Organometallics published new progress about Hydride transfer. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Subirats, Xavier published the artcileCharacterization of hydrophilic interaction liquid chromatography retention by a linear free energy relationship. Comparison to reversed- and normal-phase retentions, Computed Properties of 584-02-1, the main research area is hydrophilic interaction liquid chromatog retention linear free energy relationship; HILIC; IAM; LFER; Normal-phase; Reversed-phase.

The Abraham solvation parameter model, a linear free energy relationship (LFER) approach, has been used to characterize a polymeric zwitterionic (sulfobetaine) column in HILIC mode. When acetonitrile (MeCN) is used in the preparation of mobile phases the main solute characteristics affecting the chromatog. behavior of analytes are the mol. size and the hydrogen-bonding (both acidity and basicity) interactions. The former property is more favorable in the acetonitrile-rich mobile phase, reducing thus the retention, but the latter reveals a higher affinity for the water layer adsorbed on the stationary phase, enhancing retention. However, if the aprotic acetonitrile is replaced by methanol, a hydrogen-bond acidic solvent, solute hydrogen-bond basicity does not contribute any more to retention, quite the opposite. Thus, a slightly different selectivity is observed in methanol/water than in acetonitrile/water. Normal-phase mode and HILIC-MeCN share the same main factors affecting retention. For reversed-phase and immobilized artificial membrane (IAM) chromatog., the solute mol. size increase retention because of the lower amount of energy required in the formation of a cavity in the solvated stationary phase. On the contrary, the analyte hydrogen-bond basicity favors interactions with the hydroorg. mobile phase and reduces retention. The determined parameters justify the reversed selectivity commonly observed in HILIC in reference to reversed-phase. In most instances, the least retained solutes in reversed-phase are the most retained in HILIC.

Analytica Chimica Acta published new progress about Chromatographic columns (polymeric zwitterionic column). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Computed Properties of 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yearty, Kasey L. published the artcileDeveloping and Implementing Multioutcome Experiments in Undergraduate Teaching Laboratories To Promote Student Ownership of the Experience: An Example Multioutcome Experiment for the Oxidation of Alcohols, SDS of cas: 584-02-1, the main research area is multioutcome experiment undergraduate teaching laboratory student experience oxidation alc.

Single-outcome experiments are used in the undergraduate instructional laboratory, particularly for large lectures associated with multiple sections of instructional laboratories, due in large part to efficiencies associated with chem. purchases, experiment preparations, and assessments. Despite the practical advantages, single-outcome experiments are not effective in encouraging students to critically analyze and interpret their acquired individual results. Instead, students are satisfied if their results are the same as or similar to all of their classmates’ results, limiting the opportunity for engagement with the laboratory content. In contrast, multioutcome experiments (MOEs) require students to explore the same chem. reaction or transformation but obtain individual results. Individualization of results is accomplished by using a set of starting materials or reagents, one of which is assigned to each student. Students do not know the identity of the assigned component but may be given possible options for its identity. Students elucidate the identity of their individualized products, using modern anal. techniques such as gas chromatog., Fourier-transform IR (FTIR) spectroscopy, and NMR (NMR) spectroscopy, and deduce the unknown component of their experiment An example MOE for the oxidation of alcs. is described herein. A traditional single-outcome experiment that utilized a common household oxidizing agent (hypochlorite bleach), rather than a heavy metal-containing alternative, was modified. For the MOE modification, one unknown secondary alc. (2-pentanol, 3-pentanol, or 3-methyl-2-butanol) was oxidized using bleach. Each student pair was assigned one of three possible unknown alcs., all of which were constitutional isomers of secondary alcs. Students knew the identities of the three possible alcs. Anal. of their oxidation products was accomplished using FTIR and benchtop 1H NMR spectroscopies. Students interpreted their spectra and deduced the identity of the unknown alc. they were assigned. This experiment provides a tangible framework to understand the applicability of the oxidation reaction and the utility of FTIR and 1H NMR spectroscopies.

Journal of Chemical Education published new progress about Gas chromatography Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, SDS of cas: 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Saavedra Moreno, Yesenia published the artcileFoam stability of flotation frothers under dynamic and static conditions, Recommanded Product: 3-Pentanol, the main research area is foam stability flotation frother dynamic static condition.

The objective of this paper is to provide a detailed understanding of the relation between frother type and foam stability under dynamic and static conditions. The dynamic foam stability for eighteen non-ionic frothers from different frother families was assessed using foaminess, which quantified the ratio of foam height to the gas superficial velocity. For all tested frothers, the foaminess increased as the concentration was increased. The static foam stability was assessed by measuring the half-life and the decay rate of the foams at different superficial gas velocities and concentrations The foam stability results showed that for aliphatic alcs., the greater the number of hydrocarbon groups, the more stable the foam was under dynamic and static conditions. For polypropylene glycols, increasing the number of propylene oxide groups increased foaminess and half-life, however, a further increase in the number of propylene oxide groups (m > 7) led to a decrease in foaminess. There was not a clear relation between the number of propylene oxide groups and the maximum foam half-life. Interestingly, the foam decay rate coefficient increased by increasing the number of propylene oxide groups. For propylene glycol Me ethers, foaminess, foam half-life and decay rate coefficient increased with an increase in the number of propylene oxide groups.

Separation and Purification Technology published new progress about Foam stability. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Recommanded Product: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Yi published the artcileThe O1/H3-preferred 1:1 H-bonding and the electron-cloud migration induced by H-bonding or non-specific interactions: A systematic study on the interactions between dimethyl phthalate and 1-, 2- or 3-alkanol (C2-C6), Name: 3-Pentanol, the main research area is dimethyl phthalate aliphatic alc hydrogen bond IR spectra.

H-bonding and non-specific interactions between di-Me phthalate (DMP) and different human body substances were considered to be mainly responsible for various health dysfunctions. However, the manner of H-bonding and the adaptability of the structure of DMP that may underpin the H-bonding/non-specific interactions have been difficult to assess and remain elusive. In this study, we set out to gain an insight into the subjects above through a systematic investigation on the interactions between DMP and 1-, 2- or 3-alkanol (C2 – C6). We calculated the H-bond distances, the C=O and C-O bond lengths and other selected structural essentials at B3LYP 6-311G(d) level. We recorded the IR spectra Band I and Band II of C=O of DMP when dissolving DMP into 11 different alkanol/n-Hexane binary solvent systems. We created and fit the equations to delineate the dependence of the absorption intensity ratio of Band II to Band I (AII/AI) on the volume-ratio of the alkanol component (x). Based on the equations, we obtained the percent of the major alkanol associates (-p), the binding constant of the 1:1 and 1:2 DMP-alkanol complexes (K1 and K2) and the ratio of the molar absorptivity of H-bonded C=O to the molar absorptivity of non-bonded C=O (εhb/εns). The -p, K1, K2 and εhb/εns values confirmed the calculated results. It can be concluded that H-bonds mainly form the 1:1 complexes at O1 and H3, leading to species O5-H1···O1 = C1 for 3-alkanols and species O5-H1···O1 = C1 and Ph-H3···O5 for 2-alkanols. The differences of the affinity of H-bonding were mainly attributed to the steric hindrance and to a lesser extent to the hydrophobic interactions and the multi-H-bond cooperativity. The electron-cloud of the DMP mol. was supposed to migrate mainly in the E1 or E4 mode to adapt to the H-bonding or non-specific interactions, resp.

Journal of Molecular Liquids published new progress about C-O bond length. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Name: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Du, Wu-Bo published the artcileRegio- and stereoselective electrochemical synthesis of sulfonylated enethers from alkynes and sulfonyl hydrazides, Recommanded Product: 3-Pentanol, the main research area is sulfonyl enether preparation green chem regioselective diastereoselective; alkyne sulfonyl hydrazide alc electrooxidative sulfonylation.

An electrooxidative direct difunctionalization of internal alkynes RCCR1 [R = Ph, 2-chlorophenyl, thiophen-2-yl, etc.; R1 = Me, cyclopropyl, 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl, etc.] with sulfonyl hydrazides R2S(O)2NHNH2 (R2 = 4-methylphenyl, 3-bromophenyl, cyclopropyl, etc.) has been developed for the construction of sulfonated enethers (E)-RC(OR3)=C(R1)S(O)2R2 (R3 = Et, 2,2,2-trifluoroethyl, cyclohexyl, etc.). In this transformation, metal catalysts or stoichiometric amount of oxidants are not required and mol. nitrogen and hydrogen are the sole byproducts, providing a simple and green approach for preparing various sulfonyl tetrasubstituted alkenes. Notably, the protocol could be efficiently scaled up and the follow-up procedures of the corresponding functionalized alkenes demonstrate the practicality of the electrochem. synthesis.

Green Chemistry published new progress about Aryl alkenes Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (sulfonyl). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Recommanded Product: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sun, Simin published the artcileDirect synthesis of highly strained bifunctionalized 2H-thiete 1,1-dioxides, Application of 3-Pentanol, the main research area is thiete dioxide preparation; sulfonyl chloride dialkyl acetylene dicarboxylate heterocyclization pyridine catalyst.

Highly strained bifunctionalized dialkyl 2H-thiete-2,3-dicarboxylate 1,1-dioxides I [R = ethenyl, 4-(trifluoromethyl)phenyl, 3-cyanophenyl, etc.; R1 = Et, pentan-3-yl, cyclohexyl; R2 = Ph, OEt, pentan-3-yloxidanyl, etc.] are directly synthesized from readily available sulfonyl chlorides RCH2 and dialkyl acetylenedicarboxylates R1O(O)CCCC(O)R2 via the pyridine-mediated [2+2] annulation. In the annulation, pyridine first eliminates HCl from sulfonyl chlorides to generate sulfenes and then nucleophilically attacks the sulfenes to form zwitterionic intermediates, which nucleophilically attack dialkyl acetylenedicarboxylates followed by an intramol. cyclization and isomerization to produce the final dialkyl 2H-thiete-2,3-dicarboxylate 1,1-dioxides I. Pyridine serves as both base and nucleophilic catalyst. The current method is an efficient strategy for direct synthesis of highly strained bifunctionalized 2H-thiete 1,1-dioxide derivatives from readily available starting materials.

Organic Chemistry Frontiers published new progress about Heterocyclization ((2+2)). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Application of 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts