Category: 579-43-1

Ayya Swamy P, Chinna;Varenikov, Andrii;de Ruiter, Graham published 《Direct Asymmetric Hydrogenation and Dynamic Kinetic Resolution of Aryl Ketones Catalyzed by an Iridium-NHC Exhibiting High Enantio- and Diastereoselectivity》. The research results were published in《Chemistry – A European Journal》 in 2020.Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol The article conveys some information:

A chiral iridium carbene-oxazoline catalyst that is able to directly and efficiently hydrogenate a wide variety of ketones such as 1-(4-fluorophenyl)ethan-1-one, hex-5-en-2-one, 2-methyl-1-tetralone, etc. in excellent yields and good enantioselectivity (up to 93% ee) is reported. Moreover, when using racemic α-substituted ketones R¹C(O)CH(CH₃)S(O)₂R² (R¹ = Ph, 4-fluorophenyl, 4-methoxyphenyl; R² = morpholin-4-yl, piperidin-1-yl, pyrrolidin-1-yl), excellent diastereoselectivities were obtained (1S,2S)-R¹CH(OH)CH(CH₃)S(O)₂R² (dr 99:1) by dynamic kinetic resolution of the in situ formed enolate. Overall, the herein described hydrogenation occurs under ambient conditions using low hydrogen pressures, providing a direct and atom efficient method towards chiral secondary alcs. such as (S)-1-(4-fluorophenyl)ethanol, (S)-hex-5-en-2-ol, (1S,2S)-2-methylcyclohexanol, etc. The experimental procedure involved many compounds, such as rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .

Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.

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Jana, Barun published 《Synthesis, characterization and crystal structure determination of aluminum hydride complexes of N,N’-Di(isopropyl)ethylenediamine ligand》. The research results were published in《Journal of Molecular Structure》 in 2021.Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol The article conveys some information:

Reaction of alane-amine adduct, AlH₃·NMe₂Et, with N,N’-di(isopropyl)ethylenediamine was conducted for the preparation of amide ligated aluminum hydride complexes via dehydrocoupling pathway. Depending on the proportion of the reagents (1:1 and 3:2) two different products (1) and (2) were isolated. Compounds 1 and 2 were characterized using different spectroscopic techniques along with the determination of solid-state mol. structure via single crystal x-ray diffraction studies. In the crystal lattice of complex 2, mols. are connected via weak Al-H…H-C hydrogen bonding supramol. interactions to form polymeric arrangements of the mol. Further, a reaction of 2 with two equivalent of 1,2-diphenylethylene-glycol generated complex 3 that was isolated in trace quantities. Mol. structure of 3 was also determined using single crystal x-ray diffraction study. And rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) was used in the research process.

Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.

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Computed Properties of C14H14O2《A mild access to chiral syn 1,2-diaryl glycols by stereoselective ring opening of ortho substituted trans 2,3-diaryl-oxiranes using Amberlyst 15 in H₂O/THF system》 was published in 2015. The authors were Lupattelli, Paolo;Chiummiento, Lucia;Funicello, Maria;Tramutola, Francesco;Marmo, Antonella;Gliubizzi, Natascia;Tofani, Daniela, and the article was included in《Tetrahedron》. The author mentioned the following in the article:

Amberlyst 15 was an efficient and green catalyst for the reaction of 2,3-diaryloxiranes with H₂O in organic co-solvent to prepare glycols in high yield. Ortho substituted trans 2,3-diaryloxiranes afforded the corresponding syn glycols stereo- and enantiospecifically. Stereoselectivity appeared related to the coordination ability of the substituents, irresp. of their electronic properties. Indeed o-OCH₃ and o-OBn substituted syn glycols were obtained in high stereochem. ratios (6/1 and 10/1, resp.), and o-OTIPS and o-NO₂ substituted ones were obtained as exclusive products, with the same ee of the parent epoxides.rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) were involved in the experimental procedure.

rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas: 579-43-1 Computed Properties of C14H14O2) has been used in the preparation of trans-methyl meso-hydrobenzoin phosphite.

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Mistry, Nisha;Fletcher, Stephen P. published 《Phosphoramidite ligands based on simple 1,2-diols: synthesis, use in copper-catalyzed asymmetric additions, and achirotopic stereogenic phosphorus centres》 in 2016. The article was appeared in 《Advanced Synthesis & Catalysis》. They have made some progress in their research.Name: rel-(1R,2S)-1,2-Diphenylethane-1,2-diol The article mentions the following:

Phosphoramidite ligands are widely used in catalysis and normally constructed from large C₂-sym. diols such as BINOL or TADDOL. We report here on new ligands I (R¹ = R² = Ph , R¹-R² = (CH₂)₄; R³, R⁴ = CHMePh, CHPh₂, ⁱPr) based on a set of simple diols, 1,2-diphenyl-1,2-ethanediol, cis- and trans-1,2-cyclohexanol, that had been previously overlooked. Ligands based on (S,S)-trans-cyclohexanediol and (R,R)-(+)-1,2-diphenyl-1,2-ethanediol, in combination with both chiral and achiral amines, were tested in 3 different copper-catalyzed asym. reactions and up to 89% ee was observed A different ligand gave the best results in each reaction examined Using meso-cis-cyclohexanediol and meso-cis-diphenyl-1,2-ethanediol with a chiral non-racemic amine gave diastereomeric ligands bearing achirotopic stereogenic phosphorus atoms which were characterized with the assistance of x-ray crystallog. and variable temperature NMR studies. This work provides a new set of ligands that may be useful in some asym. reactions when phosphoramidites based on BINOL and TADDOL are ineffective. We also identify a novel stereochem. feature of phosphoramidites that may be useful in asym. catalysis and ligand design. To complete the study, the researchers used rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .

Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Name: rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.

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Obara, Naoyuki;Hirasawa, Shota;Tamura, Masazumi;Nakagawa, Yoshinao;Tomishige, Keiichi published 《Oxidative Cleavage of Vicinal Diols with the Combination of Platinum and Vanadium Catalysts and Molecular Oxygen》 in 2016. The article was appeared in 《ChemCatChem》. They have made some progress in their research.Related Products of 579-43-1 The article mentions the following:

The combination of Pt/C and V₂O₅ catalysts gave good performance for the oxidative cleavage of trans-1,2-cyclohexanediol into adipic acid via 2-hydroxycyclohexanone. The yield of adipic acid reached 90% in the one-pot oxidative cleavage of trans-1,2-cyclohexanediol. The yield was higher than that obtained in the oxidation of 2-hydroxycyclohexanone with V catalyst, and the higher yield was due to the low 2-hydroxycyclohexanone concentration during the one-pot oxidation of trans-1,2-cyclohexanediol. Cyclic vicinal diols having a six-membered ring and linear vicinal diols having two secondary OH groups were converted into dicarboxylic acids and two carboxylic acids, resp. The activity of the Pt catalyst decreased during the reaction, and the activity was partially restored by treating the used catalyst with H₂ at 573 K. Even without regeneration, the turnover number based on total Pt could reach ≈1000 in a long reaction with an increased amount of trans-1,2-cyclohexanediol. And rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) was used in the research process.

rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas: 579-43-1 Related Products of 579-43-1) has been used in the preparation of trans-methyl meso-hydrobenzoin phosphite.

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Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol《Convenient synthesis of ethylene carbonates from carbon dioxide and 1,2-diols at atmospheric pressure of carbon dioxide》 was published in 2016. The authors were Kitamura, Tsugio;Inoue, Yusuke;Maeda, Taisei;Oyamada, Juzo, and the article was included in《Synthetic Communications》. The author mentioned the following in the article:

An efficient and convenient synthesis of ethylene carbonates was achieved by the reaction of carbon dioxide with 1,2-diols in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), followed by treatment with 1-bromobutane. This DBU-promoted transformation proceeded at atm. pressure of carbon dioxide at 25°C and gave ethylene carbonates in good yields. The experimental procedure involved many compounds, such as rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .

Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.

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Liu, Mingxin;Tan, Lida;Rashid, Roksana T.;Cen, Yunen;Cheng, Shaobo;Botton, Gianluigi;Mi, Zetian;Li, Chao-Jun published 《GaN nanowires as a reusable photoredox catalyst for radical coupling of carbonyl under blacklight irradiation》 in 2020. The article was appeared in 《Chemical Science》. They have made some progress in their research.Synthetic Route of C14H14O2 The article mentions the following:

Using the carbonyl coupling reaction as a proof-of-concept, herein, a photo-pinacol coupling reaction of various ketones R¹C(O)R² (R¹ = Me, Ph, 3-phenoxypropyl, etc.; R² = H, Me, n-Pr, Ph, etc.) and 3-methoxy-Estra-1,3,5(10)-trien-17-one catalyzed by GaN nanowires under ambient light at room temperature with methanol as a solvent and sacrificial reagent was reported. By simply tuning the dopant, the GaN nanowire shows significantly enhanced electronic properties. The catalyst showed excellent stability, reusability and functional tolerance. All reactions could be accomplished with a single piece of nanowire on Si-wafer. The experimental procedure involved many compounds, such as rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .

rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas: 579-43-1 Synthetic Route of C14H14O2) has been used in the preparation of trans-methyl meso-hydrobenzoin phosphite.

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Escande, Vincent;Lam, Chun Ho;Grison, Claude;Anastas, Paul T. published 《EcoMnOx, a Biosourced Catalyst for Selective Aerobic Oxidative Cleavage of Activated 1,2-Diols》. The research results were published in《ACS Sustainable Chemistry & Engineering》 in 2017.Quality Control of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol The article conveys some information:

A novel catalyst, EcoMnOx, was prepared from waste biomass of Mn-hyperaccumulating plants. The valorization of this Mn-rich biomass is an alternative to its costly usual disposing and provides a new source of Mn. Extracted metal ions, including Mn²⁺, were oxidized in mild conditions by H₂O₂/NaOH to afford EcoMnOx, as a polymetallic oxide material containing from 8.9 to 14.1 wt % Mn. Spectroscopic studies of this material revealed the presence of Mn layered mixed oxides, rich in Mn^IV along with Mn^III and Mn^II species. EcoMnOx catalytic properties were assessed in the aerobic oxidative cleavage of 1,2-diols, under atm. pressure of O₂ or air. With only 10 mol % Mn, up to complete conversions were obtained on activated benzylic and allylic diols, with excellent selectivity toward aldehydes or ketones (98-99%). Moreover, because of its heterogeneous nature, the catalyst can be removed easily by filtration, and reapplied for a min. of six successive runs without any loss of activity. Finally, E-factor anal. showed the EcoMnOx generates 4 to 17 times less waste compared to classical reagents such as NaIO₄ and Pb(OAc)₄, resp., highlighting the sustainable assets of this new heterogeneous catalyst. And rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) was used in the research process.

rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas: 579-43-1 Quality Control of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) has been used in the preparation of trans-methyl meso-hydrobenzoin phosphite.

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Arunachalam, Rajendran;Chinnaraja, Eswaran;Valkonen, Arto;Rissanen, Kari;Sen, Shovan K.;Natarajan, Ramalingam;Subramanian, Palani S. published 《Enantiomeric Resolution of Asymmetric-Carbon-Free Binuclear Double-Stranded Cobalt(III) Helicates and Their Application as Catalysts in Asymmetric Reactions》. The research results were published in《Inorganic Chemistry》 in 2018.Name: rel-(1R,2S)-1,2-Diphenylethane-1,2-diol The article conveys some information:

A series of double-stranded binuclear helicates [Co₂(H1)₂]⁴⁺, [Co₂(H2)₂]⁴⁺, and [Co₂(H3)₂]⁴⁺, derived from monodeprotonated bis-pyridyl hydrazine-based ligands of H₂1, H₂2, and H₂3 with one, two, and three -CH₂ spacers, were obtained. These asym.-carbon-free racemic helicates were separated into their ΔΔ and ΛΛ enantiomers. The resolved helicates were examined for the first time as enantioselective catalysts in asym. benzoylation and nitroaldol reactions. To complete the study, the researchers used rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .

Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Name: rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.

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Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol《Enantioselective acyl transfer catalysis by a combination of common catalytic motifs and electrostatic interactions》 was published in 2016. The authors were Mandai, Hiroki;Fujii, Kazuki;Yasuhara, Hiroshi;Abe, Kenko;Mitsudo, Koichi;Korenaga, Toshinobu;Suga, Seiji, and the article was included in《Nature Communications》. The author mentioned the following in the article:

It was demonstrated that by attaching a binaphthyl moiety, appropriately modified to establish H-bonding interactions within the key intermediates in the catalytic cycle and a 4-aminopyridyl unit, exceptionally efficient organic mols. could be prepared that facilitated enantioselective acyl transfer reactions. As little as 0.5 mol% of a member of the new catalyst class was sufficient to generate acyl-substituted all-carbon quaternary stereogenic centers in quant. yield and in up to 98:2 enantiomeric ratio (er) in 5 h. Kinetic resolution or desymmetrization of 1,2-diol could be performed with high efficiency and enantioselectivity as well.rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) were involved in the experimental procedure.

Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.

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