Category: 57044-25-4

《Pyrolytic characteristics of fine materials from municipal solid waste using TG-FTIR, Py-GC/MS, and deep learning approach: Kinetics, thermodynamics, and gaseous products distribution》 was written by Lin, Kunsen; Tian, Lu; Zhao, Youcai; Zhao, Chunlong; Zhang, Meilan; Zhou, Tao. Safety of (R)-Oxiran-2-ylmethanol And the article was included in Chemosphere on April 30 ,2022. The article conveys some information:

Fine materials (FM) from municipal solid waste (MSW) classification require disposal, and pyrolysis is a feasible method for the treatments. Hence, the behavior, kinetics, and products of FM pyrolysis were investigated in this study. A deep learning algorithm was firstly employed to predict and verify the TG data during the process of FM pyrolysis. The results showed that FM pyrolysis could be divided into drying (<138 °C), de-volatilization (138-570 °C), and decomposition stage (≥570 °C above). The de-volatilization can further be divided into stage 2 and stage 3, with values of activation energy estimated by Flynn-Wall-Ozawa and Kissinger-Akahira-Sunose methods as 123.35 and 172.95 kJ/mol, resp. The gas products like H2O, CO2, CH4, and CO, as well as functional groups like phenols and carbonyl (C=O), were all detected during the process of FM pyrolysis by thermogravimetric-fourier transform IR spectrometry at a heating rate of 10 °C/min. The main species detected by pyrolysis-gas chromatog.-mass spectrometry analyzer included acid (41.98%) and aliphatic hydrocarbon (22.44%). Finally, the 1D-CNN-LSTM algorithm demonstrated an outstanding generalization capability to predict the relationship between FM composition and temperature, with R2 reaching 93.91%. In sum, this study provided a reference for the treatment of FM from MSW classification as well as the feasibility and practicability of deep learning applied in pyrolysis. The experimental part of the paper was very detailed, including the reaction process of (R)-Oxiran-2-ylmethanol(cas: 57044-25-4Safety of (R)-Oxiran-2-ylmethanol)

(R)-Oxiran-2-ylmethanol(cas: 57044-25-4) is a chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.Safety of (R)-Oxiran-2-ylmethanol

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Alcohol – Wikipedia,
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In 2020,Molecules included an article by Moriyama, Mizuki; Nakata, Kohei; Fujiwara, Tetsuya; Tanabe, Yoo. Category: alcohols-buliding-blocks. The article was titled 《Divergent asymmetric total synthesis of all four pestalotin diastereomers from (R)-glycidolã€? The information in the text is summarized as follows:

All four chiral pestalotin diastereomers were synthesized in a straightforward and divergent manner from common (R)-glycidol. Catalytic asym. Mukaiyama aldol reactions of readily-available bis(TMSO)diene (Chan’s diene) with (S)-2-benzyloxyhexanal derived from (R)-glycidol produced a syn-aldol adduct with high diastereoselectivity and enantioselectivity using a Ti(iOPr)4/(S)-BINOL/LiCl catalyst. Diastereoselective Mukaiyama aldol reactions mediated by catalytic achiral Lewis acids directly produced not only a (1’S,6S)-pyrone precursor via the syn-aldol adduct using TiCl4, but also (1’S,6R)-pyrone precursor via the antialdol adduct using ZrCl4, in a stereocomplementary manner. A Hetero-Diels-Alder reaction of similarly available mono(TMSO)diene (Brassard’s diene) with (S)-2-benzyloxyhexanal produced the (1’S,6S)-pyrone precursor promoted by Eu(fod)3 and the (1’S,6R)-pyrone precursor Et2AlCl. Debenzylation of the (1’S,6S)-precursor and the (1’S,6R)-precursor furnished natural (-)-pestalotin (99% ee, 7 steps) and unnatural (+)-epipestalotin (99% ee, 7 steps), resp. Mitsunobu inversions of the obtained (-)-pestalotin and (+)-epipestalotin successfully produced the unnatural (+)-pestalotin (99% ee, 9 steps) and (-)-epipestalotin (99% ee, 9 steps), resp., in a divergent manner. All four of the obtained chiral pestalotin diastereomers possessed high chem. and optical purities (optical rotations, 1H-NMR, 13C-NMR, and HPLC measurements). After reading the article, we found that the author used (R)-Oxiran-2-ylmethanol(cas: 57044-25-4Category: alcohols-buliding-blocks)

(R)-Oxiran-2-ylmethanol(cas: 57044-25-4) is a chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

He, Yu-Tao; Li, Li-Xuan; Lin, Xiaohong; Hou, Bao-Long; Li, Chuang-Chuang published an article on January 14 ,2022. The article was titled 《Synthesis of Various Bridged Ring Systems via Rhodium-Catalyzed Bridged (3+2) Cycloadditionsã€? and you may find the article in Organic Letters.Application of 57044-25-4 The information in the text is summarized as follows:

Here, the authors describe the rhodium-catalyzed bridged [3+2]-cycloaddition cascade reactions of N-sulfonyl-1,2,3-triazoles, which allowed the efficient diastereoselective construction of various functionalized and synthetically challenging bridged ring systems. This simple, direct transformation had a broad substrate scope and excellent functional group tolerance. The highly strained polycyclic bicyclo[2.2.2]octa[b]indole core of fruticosine was synthesized efficiently using this methodol. The experimental process involved the reaction of (R)-Oxiran-2-ylmethanol(cas: 57044-25-4Application of 57044-25-4)

(R)-Oxiran-2-ylmethanol(cas: 57044-25-4) is a chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.Application of 57044-25-4

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kimoto, Michiko; Soh, Si Hui Gabriella; Tan, Hui Pen; Okamoto, Itaru; Hirao, Ichiro published an article on January 31 ,2021. The article was titled 《Cognate base-pair selectivity of hydrophobic unnatural bases in DNA ligation by T4 DNA ligaseã€? and you may find the article in Biopolymers.COA of Formula: C3H6O2 The information in the text is summarized as follows:

We present cognate base pair selectivity in template-dependent ligation by T4 DNA ligase using a hydrophobic unnatural base pair (UBP), Ds-Pa. T4 DNA ligase efficiently recognizes the Ds-Pa pairing at the conjugation position, and Ds excludes the noncognate pairings with the natural bases. Our results indicate that the hydrophobic base pairing is allowed in enzymic ligation with higher cognate base-pair selectivity, relative to the hydrogen-bond interactions between pairing bases. The efficient ligation using Ds-Pa can be employed in recombinant DNA technol. using genetic alphabet expansion, toward the creation of semi-synthetic organisms containing UBPs. In addition to this study using (R)-Oxiran-2-ylmethanol, there are many other studies that have used (R)-Oxiran-2-ylmethanol(cas: 57044-25-4COA of Formula: C3H6O2) was used in this study.

(R)-Oxiran-2-ylmethanol(cas: 57044-25-4) is a chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.COA of Formula: C3H6O2

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Borrel, Julien; Pisella, Guillaume; Waser, Jerome published an article on January 17 ,2020. The article was titled 《Copper-Catalyzed Oxyalkynylation of C-S Bonds in Thiiranes and Thietanes with Hypervalent Iodine Reagents》, and you may find the article in Organic Letters.Formula: C3H6O2 The information in the text is summarized as follows:

We report the oxyalkynylation of thiiranes and thietanes using ethynylbenziodoxolone reagents (EBXs) to readily access functionalized building blocks bearing an alkynyl, a benzoate, and an iodide group. The reaction proceeds with high atom efficiency most likely through an alkynyl-episulfonium intermediate. The transformation is copper-catalyzed and compatible with a large array of thiiranes and thietanes. In the experimental materials used by the author, we found (R)-Oxiran-2-ylmethanol(cas: 57044-25-4Formula: C3H6O2)

(R)-Oxiran-2-ylmethanol(cas: 57044-25-4) is a chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.Formula: C3H6O2

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jadhav, Sandip B.; Chegondi, Rambabu published their research in Organic Letters on December 20 ,2019. The article was titled 《Diastereoselective Desymmetrization of p-Quinamines through Regioselective Ring Opening of Epoxides and Aziridines》.Recommanded Product: (R)-Oxiran-2-ylmethanol The article contains the following contents:

A highly diastereoselective desymmetrization of p-quinamines via regioselective ring opening of epoxides and aziridines under mild conditions has been developed. A chairlike six-membered transition state with minimized 1,3-diaxial interactions explains the relative stereoselectivity of the cyclization reaction. This transition-metal free [3 + 3] annulation reaction provides rapid access to fused bicyclic morpholines and piperazines with a tetrasubstituted carbon center in high yields. In addition, it also allows the synthesis of enantioenriched products by using easily accessible chiral nonracemic epoxides and aziridines. In the experimental materials used by the author, we found (R)-Oxiran-2-ylmethanol(cas: 57044-25-4Recommanded Product: (R)-Oxiran-2-ylmethanol)

(R)-Oxiran-2-ylmethanol(cas: 57044-25-4) is a chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.Recommanded Product: (R)-Oxiran-2-ylmethanol

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application In Synthesis of (R)-Oxiran-2-ylmethanolOn March 19, 2021, Bold, Christian P.; Klaus, Cindy; Pfeiffer, Bernhard; Schurmann, Jasmine; Lombardi, Rafael; Lucena-Agell, Daniel; Diaz, J. Fernando; Altmann, Karl-Heinz published an article in Organic Letters. The article was 《Studies toward the Synthesis of an Oxazole-Based Analog of (-)-Zampanolide》. The article mentions the following:

Studies are described toward the synthesis of an oxazole-based analog I of (-)-zampanolide. Construction of (-)-dactylolide analog 22 was achieved via alc. II and acid III through esterification and Horner-Wadsworth-Emmons (HWE)-based macrocyclization; however, attempts to attach (Z,E)-sorbamide to I proved unsuccessful. The C(8)-C(9) double bond of the macrocycle was prone to migration into conjugation with the oxazole ring, which may generally limit the usefulness of zampanolide analogs with aromatic moieties as tetrahydropyran replacements. The experimental process involved the reaction of (R)-Oxiran-2-ylmethanol(cas: 57044-25-4Application In Synthesis of (R)-Oxiran-2-ylmethanol)

(R)-Oxiran-2-ylmethanol(cas: 57044-25-4) is a chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.Application In Synthesis of (R)-Oxiran-2-ylmethanol

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Synthetic Communications included an article by Subba, Srijana; Saha, Sumit. Related Products of 57044-25-4. The article was titled 《Diyne mediated formal synthesis of (-)-A26771B》. The information in the text is summarized as follows:

A formal asym. synthesis of (-)-A26771B was achieved where optically active glycidol and Noyori asym. hydrogenation were applied to introduce asym. centers. Com. available 1,7-octadiyne, (R)-glycidol and acetaldehyde were used as the starting materials. The outlined synthetic strategy involved fewer number of synthetic steps, applying simple chem. transformations. In the experimental materials used by the author, we found (R)-Oxiran-2-ylmethanol(cas: 57044-25-4Related Products of 57044-25-4)

(R)-Oxiran-2-ylmethanol(cas: 57044-25-4) is a chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.Related Products of 57044-25-4

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lewin, Anita H.; Brieaddy, Larry; Deschamps, Jeffrey R.; Imler, Gregory H.; Mascarella, S. Wayne; Reddy, P. Anantha; Carroll, F. Ivy published an article on January 16 ,2019. The article was titled 《Synthesis and Characterization of the Selective, Reversible PKCβ Inhibitor (9S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione, Ruboxistaurin (LY333531)》, and you may find the article in ACS Chemical Neuroscience.Reference of (R)-Oxiran-2-ylmethanol The information in the text is summarized as follows:

The demonstrated role of PKCβ in mediating amphetamine-stimulated dopamine efflux, which regulates amphetamine-induced dopamine transporter trafficking and activity, has promoted the research use of the selective, reversible PKCβ inhibitor (9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione, ruboxistaurin. Despite the interest in development of ruboxistaurin as the mesylate monohydrate (Arxxant) for the treatment of diabetic retinopathy, macular edema, and nephropathy, several crucial details in physicochem. characterization were erroneous or missing. This report describes the synthesis and full characterization of ruboxistaurin free base (as a monohydrate), including X-ray crystallog. to confirm the absolute configuration, and of the mesylate salt, isolated as a hydrate containing 1.5 mol of water per mol.(R)-Oxiran-2-ylmethanol(cas: 57044-25-4Reference of (R)-Oxiran-2-ylmethanol) was used in this study.

(R)-Oxiran-2-ylmethanol(cas: 57044-25-4) is a chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.Reference of (R)-Oxiran-2-ylmethanol

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Recommanded Product: (R)-Oxiran-2-ylmethanolOn October 15, 2020 ,《Determining the relative reactivity of sulfate, bisulfate, and organosulfates with epoxides on secondary organic aerosol》 was published in ACS Earth and Space Chemistry. The article was written by Aoki, Erika; Sarrimanolis, Jon N.; Lyon, Sophie A.; Elrod, Matthew J.. The article contains the following contents:

Extensive laboratory and field studies have identified nucleophilic addition reactions of isoprene epoxydiols (IEPOX) as key pathways for the formation of isoprene-derived secondary organic aerosol (SOA). Organosulfates are important reaction products of these processes, but it is unclear whether sulfate and/or bisulfate nucleophiles are responsible for their formation and whether the organosulfates themselves can serve as nucleophiles in oligomer-forming reactions. The relative reactivities (nucleophilic strengths relative to water) of sulfate, bisulfate, and Me sulfate anion were measured through a series of model epoxide-nucleophile experiments using NMR (NMR) spectroscopy. These experiments also helped establish a rigorous understanding of the effects of differing carbon substitution and functional groups of epoxides on the modulation of the effective nucleophilicites of sulfate, bisulfate, and Me sulfate anions. It was determined that the nucleophilicites of bisulfate and Me sulfate anions were about 100 and 50 times, resp., weaker than sulfate toward most of the epoxides studied, which was rationalized by computational estimates of their thermodn. basicities. Therefore, for most SOA acidity situations, sulfate-epoxide reactions are expected to be the main source of organosulfate aerosol constituents. Because sulfate-epoxide reactions stoichiometrically consume acid, these reactions also have the capability of raising the pH of SOA, thus slowing down all acid-catalyzed chem. processes. No evidence for the reaction of the Me sulfate anion was observed with the abundant atmospherically relevant epoxide, trans-β-IEPOX, thus suggesting that oligomerization reactions via epoxide-organosulfate reactions may not be able to compete with stronger (such as sulfate) or more abundant (such as water) nucleophiles on actual SOA.(R)-Oxiran-2-ylmethanol(cas: 57044-25-4Recommanded Product: (R)-Oxiran-2-ylmethanol) was used in this study.

(R)-Oxiran-2-ylmethanol(cas: 57044-25-4) is a chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.Recommanded Product: (R)-Oxiran-2-ylmethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts