Category: 5344-90-1

Tang, Shi; Ding, Shumin; Li, Dan; Li, Lianjie; Zhao, Haixia; Chai, Minxue; Wang, Jian published the artcile< Palladium-catalysed imidoylative spirocyclization of 3-(2-isocyanoethyl)indoles>, Recommanded Product: (2-Aminophenyl)methanol, the main research area is isocyanoalkyl indole organoiodide palladium catalyst tandem dearomative imidolylative spirocyclization; spiroindole azaarene preparation.

A palladium-catalyzed construction of spiroindolines through dearomative spirocyclization of 3-(2-isocyanoethyl)indoles was developed. 2′-Aryl-, vinyl-, and alkyl-substituted spiroindolines were accessed under mild conditions with excellent functional group tolerance. C1-tethered oxindole- and indole-spiroindoline bisheterocycles were generated in high yields via alkene/allene insertion and an imidoylative spirocyclization cascade. Addnl., a tandem dearomatization of two different indoles was realized with N-(2-bromobenzoyl)indoles as the electrophilic coupling partner of 3-(2-isocyanoethyl)indoles, affording polyindoline – spiroindoline bisheterocyclic scaffolds conveniently. Under the catalysis of Pd(OAc)2 and a spinol-derived phosphoramidite ligand, chiral spiroindolines were successfully accessed with up to 95% yield and 85% ee.

Chemical Communications (Cambridge, United Kingdom) published new progress about Aromatic amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Recommanded Product: (2-Aminophenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Ling; Zhang, Shiqi; Deng, Xiongfei; Li, Guangxun; Tang, Zhuo; Zhao, Gang published the artcile< Preparation and Application of α-Imino Ketones through One-Pot Tandem Reactions Based on Heyns Rearrangement>, Related Products of 5344-90-1, the main research area is amine hydroxyketone regioselective diastereoselective tandem Heyns rearrangement oxidation; imino ketone preparation; hydroxyketone aminoalc regioselective diastereoselective tandem Heyns rearrangement oxidation; ketal preparation.

A metal-free and operationally simple strategy was developed to generate α-imino ketones with high regioselectivity. Meanwhile, the method allowed for the preparation of various N,O-ketals with high regioselectivities and diastereoselectivities through cascade reactions in one pot.

Organic Letters published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Related Products of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chakraborty, Gargi; Sikari, Rina; Das, Siuli; Mondal, Rakesh; Sinha, Suman; Banerjee, Seemika; Paul, Nanda D. published the artcile< Dehydrogenative Synthesis of Quinolines, 2-Aminoquinolines, and Quinazolines Using Singlet Diradical Ni(II)-Catalysts>, Application of C7H9NO, the main research area is quinoline biomimetic synthesis; aminoquinoline biomimetic synthesis; quinazoline biomimetic synthesis; nickel complex diamine singlet diradical oxidative condensation coupling catalyst.

Simple, straightforward, and atom economic methods for the synthesis of quinolines, 2-aminoquinolines, and quinazolines via biomimetic dehydrogenative condensation/coupling reactions, catalyzed by well-defined inexpensive and easy to prepare singlet diradical Ni(II)-catalysts featuring two antiferromagnetically coupled singlet diradical diamine type ligands are described. Various polysubstituted quinolines, 2-aminoquinolines, and quinazolines were synthesized in moderate to good yields from different low-cost and readily accessible starting materials. Several control experiments were carried out to get insight into the reaction mechanism which shows that the nickel and the coordinated diamine ligands participate in a synergistic way during the dehydrogenation of alcs.

Journal of Organic Chemistry published new progress about Acetonitriles Role: RCT (Reactant), RACT (Reactant or Reagent) (phenylacetonitriles). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application of C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yadav, Anamika; Ambule, Mayur D.; Kant, Ruchir; Srivastava, Ajay K. published the artcile< Silver/Palladium Relay Catalyzed Cross-Coupling of N'-Acetyl-8-quinolinesulfonylhydrazide with Alcohols: An Easy Access to 8-Quinolinesulfinate Esters>, Application In Synthesis of 5344-90-1, the main research area is silver palladium catalyzed cross coupling quinolinesulfonyl hydrazide alc; quinolinesulfinate ester preparation.

An efficient strategy for the synthesis of unexplored 8-quinolinesulfinate esters has been reported. The method involves in situ generation of quinoline sulfinate from N’-acetylquinoline-8-sulfonohydrazide via silver mediated cleavage followed by palladium-catalyzed cross-coupling with 1° and 2° alcs. to yield sulfinate esters. A variety of substituted alcs. were successfully employed in the reaction. Control experiments performed to understand the mechanism, revealed that the transformation follows a radical pathway and the alc. oxygen get incorporated in the resulting sulfinate esters. Two of the chirally pure alcs. were also used in the transformation to study the diastereoselectivity in the reaction. In order to demonstrate the synthetic utility, a representative allyl quinoline-8-sulfinate (I) was successfully converted into the 8-(allylsulfonyl)quinoline (II) via palladium(II) acetate mediated isomerization.

European Journal of Organic Chemistry published new progress about Hydrazides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application In Synthesis of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Verma, Ashutosh; Hazra, Susanta; Dolui, Pritam; Elias, Anil J. published the artcile< Ruthenium-Catalyzed Synthesis of α-Alkylated Ketones and Quinolines in an Aqueous Medium via a Hydrogen-Borrowing Strategy Using Ketones and Alcohols>, Category: alcohols-buliding-blocks, the main research area is ruthenium catalyst preparation; aryl ketone alc ruthenium catalyst green alkylation; phenyl arylpropanone preparation; arylquinoline preparation.

A simple, efficient, and sustainable method for the synthesis of α-alkylated ketones and quin50556012Aolines using a hydrogen-borrowing strategy was reported, which has emerged as a greener alternative in organic transformation reactions. Synthesis of a range of α-alkylated ketones and quinoline derivatives was achieved by using the water-soluble [Ru(8-AQ)Cl(p-cym.)]+Cl- [Ru]-1 (AQ=aminoquinoline) catalyst with water as the reaction medium. By adopting this strategy, α-alkylated ketones and quinolines was synthesized using ketones or secondary alcs. as starting materials and the primary alc. as a green and naturally abundant alkylating agent.

Asian Journal of Organic Chemistry published new progress about Alkylation. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Putta, V. P. Rama Kishore; Vodnala, Nagaraju; Gujjarappa, Raghuram; Tyagi, Ujjawal; Garg, Aakriti; Gupta, Sreya; Pujar, Prasad Pralhad; Malakar, Chandi C. published the artcile< Reagent-Controlled Divergent Synthesis of 2-Amino-1,3-Benzoxazines and 2-Amino-1,3-Benzothiazines>, Computed Properties of 5344-90-1, the main research area is isothiocyanate aminobenzyl alc thiourea iodine chemoselective dehydrosulfurization cyclodehydration; benzoxazine one pot preparation; aminobenzyl alc isothiocyanate thiourea propylphosphonic anhydride chemoselective cyclodehydration; benzothiazine one pot preparation.

A reagent-controlled chemoselective process has been devised for the synthesis of 4H-1,3-benzoxazines and related biol. important heterocycles in high yields under mild conditions. These scaffolds could be efficiently constructed using two different chemoselective reactions that rely on the choice of reagents and reaction conditions. The treatment of various 2-amino-arylalkyl alcs. with isothiocyanates afforded thiourea intermediates, which were reacted in situ with mol. iodine in the presence of triethylamine to give 2-amino-4H-1,3-benzoxazines, whereas the corresponding 2-amino-4H-1,3-benzothiazines were obtained by the reaction of thiourea intermediates in the presence of T3P (a mild cyclodehydrating agent) and triethylamine as the base. The described protocol represents the first example for the synthesis of 4H-1,3-benzoxazines via the dehydrosulfurization method using mol. iodine as the reagent.

Journal of Organic Chemistry published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent) (amino). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Computed Properties of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Cheng published the artcile< Solvent-induced synthesis and crystal structures of copper(II) complexes derived from 4-chloro-2-[(2-hydroxymethylphenylimino)methyl]phenol with antibacterial activity>, Synthetic Route of 5344-90-1, the main research area is copper hydroxymethylphenyliminophenolate multinuclear complex preparation bactericide; crystal structure copper hydroxymethylphenyliminophenolate multinuclear complex.

Two new polynuclear copper(II) complexes, [Cu2L2] (1) and [Cu4L4]CH2Cl2 (2), where L is 4-chloro-2-[(2-hydroxymethylphenylimino)methyl]phenolate, were synthesized and characterized by IR and UV-Vis spectroscopy. The mol. structures of the complexes were confirmed by single-crystal X-ray determination The Cu ions in dinuclear complex 1 are in square planar coordination, while those in tetranuclear complex 2 are in square pyramidal coordination. The solvents used in the synthesis and crystallization play an important role for the formation of the final structures of the complexes. The Schiff base and two copper complexes were assayed for antibacterial activities by the MTT method.

Journal of Coordination Chemistry published new progress about Antibacterial agents. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Synthetic Route of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gholinejad, Mohammad; Dasvarz, Neda; Shojafar, Mohammad; Sansano, Jose M. published the artcile< Starch functionalized creatine for stabilization of gold nanoparticles: Efficient heterogeneous catalyst for the reduction of nitroarenes>, Quality Control of 5344-90-1, the main research area is starch creatine stabilization gold nanoparticle catalyst reduction nitroarene.

Selective reduction of nitroarom. pollutants into amines with recoverable and reusable heterogeneous catalysts is highly desirable. Herein, we prepared and characterized an efficient novel catalyst comprising 4 nm size Au nanoparticles supported on creatine modified starch. Using this catalyst, efficient reduction of nitroarenes into amines at room temperature in aqueous media was achieved. The presence of creatine in the structure of the catalyst plays important role in amount of Au loading, efficiency of the catalyst, recycling times, and leaching of Au compared to starch supported Au without creatine.

Inorganica Chimica Acta published new progress about Aromatic nitro compounds Role: POL (Pollutant), RCT (Reactant), OCCU (Occurrence), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Quality Control of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yalcinkaya, Sueleyman; Cakmak, Didem; Seymen, Kuebra; Demetguel, Cahit published the artcile< Electrochemical synthesis and characterization of poly (o-amino benzyl alcohol) and poly (o-amino benzyl alcohol-co-o-anisidine)>, Synthetic Route of 5344-90-1, the main research area is electrochem synthesis polyamino benzyl alc anisidine copolymer.

In this study; poly (o-amino benzyl alc.) and poly (o-amino benzyl alc.-co-o-anisidine) copolymer films were electrochem. synthesized by cyclic voltammetry technique on the platinum electrode. The synthesis of copolymer films was achieved in various monomers feed ratio (o-amino benzyl alc.: o-anisidine; 8:2, 1:1, 2:8) of o-amino benzyl alc. and o-anisidine. Different solution types were tested in aqueous and non-aqueous media, especially during the synthesis process, as the electrolyte medium. As a result of the experiments, it was determined that sulfuric acid solution was the most suitable solution for both homopolymer and copolymer film growth. Homopolymer and copolymer samples were characterized by FT-IR, cyclic voltammetry (CV), SEM, digital images and TGA/DTA techniques. The CV, SEM and digital images results indicated that the solution which has high ratio of monomer is more effective in copolymer film synthesis mechanism. TGA results showed that the 1:1 copolymer film had higher thermal stability than the films at other monomer ratios. Also, electrochem. studies exhibited that the copolymer film in 1:1 ratio is partially more electrochem. stable than other copolymer films.

Journal of Applied Polymer Science published new progress about Conducting polymers. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Synthetic Route of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Donthireddy, S. N. R.; Singh, Vivek Kumar; Rit, Arnab published the artcile< A heteroditopic NHC and phosphine ligand supported ruthenium(II)-complex: an effective catalyst for the N-alkylation of amides using alcohols>, Name: (2-Aminophenyl)methanol, the main research area is alkylation aromatic amide aralkyl alc ruthenium chelate carbene catalyst; ruthenium imidazolylidene triazolylidene mesoionic carbene preparation amide alkylation catalyst; secondary aromatic amide benzyl preparation alkylation arenemethanol ruthenium catalyst.

A ruthenium(II) complexes [(p-cymene)RuCl(1-MeIm-3-CH2Trz-1-C6H4R)] (Im = 2-imidazolylidene, Trz = 1,2,3-triazol-4-yl-5-ylidene; R = 2,4,6-Me3, 4-MeO, 4-CF3) supported by chelate NHC and mesoionic carbene ligands in combination with a diphosphine ligand (dppe, dppf) was shown to be a highly effective catalyst for the N-alkylation of diverse aromatic amides ArCONH2 using readily available primary aralkyl alcs. Ar1CH2OH, yielding N-benzylamides ArCONHCH2Ar1 (Ar, Ar1 = substituted Ph, pyridyl, thienyl, naphthyl). A wide range of secondary amides was thus obtained in excellent yields (up to 98%) employing a low catalyst loading of 0.2 mol% and a substoichiometric amount of base. The 1H NMR and ESI-MS analyses support the participation of a N-heterocyclic carbene and phosphine supported Ru-H species in the catalytic cycle and the mechanistic studies including the deuterium labeling experiment suggest the involvement of a borrowing hydrogen protocol. Addnl., the present catalytic system was also revealed to be efficient for the selective mono-alkylation and unsym. di-alkylation of 4-aminobenzamides which have not been studied before to the extent of our knowledge.

Catalysis Science & Technology published new progress about Alkylation catalysts. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Name: (2-Aminophenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts