Category: 5344-90-1

Maji, Ankur; Singh, Anshu; Singh, Neetu; Ghosh, Kaushik published the artcile< Efficient Organoruthenium Catalysts for α-Alkylation of Ketones and Amide with Alcohols: Synthesis of Quinolines via Hydrogen Borrowing Strategy and their Mechanistic Studies>, Recommanded Product: (2-Aminophenyl)methanol, the main research area is preparation quinoline organoruthenium catalyst; ketone alc alkylation; amino benzyl alc ketone cyclization; tertiary amide alc alkylation.

A new family of phosphine free organometallic ruthenium(II) catalysts supported by bidentate NN Schiff base ligands I (R = NMe2, NEt2) and II was prepared These half-sandwich complexes acted as catalysts for C-C bond formation and exhibited excellent performance in the dehydrogenative coupling of ketones and amides. In the synthesis of C-C bonds, alcs. were utilized as the alkylating agent. A broad range of substrates, including sterically hindered ketones and alcs., were well tolerated under the optimized conditions (TON up to 47000 and TOF up to 11750 h-1). This ruthenium (II) catalysts were also active towards the dehydrogenative cyclization of o-amino benzyl alc. for the formation of quinolines derivatives Various polysubstituted quinolines were synthesized in moderate to excellent yields (TON up to 71000 and TOF up to 11830 h-1). Control experiments were carried out and the ruthenium hydride intermediate was characterized to support the reaction mechanism and a probable reaction pathway of dehydrogenative coupling for the C-C bond formation has been proposed.

ChemCatChem published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Recommanded Product: (2-Aminophenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hu, Wenkang; Zhang, Yilin; Zhu, Haiyan; Ye, Dongdong; Wang, Dawei published the artcile< Unsymmetrical triazolylnaphthyridinylpyridine bridged highly active copper complexes supported on reduced graphene oxide and their application in water>, Recommanded Product: (2-Aminophenyl)methanol, the main research area is copper triazolylnaphthyridinylpyridine complex preparation catalyst.

A novel unsym. triazolylnaphthyridinylpyridine ligand was designed and synthesized, and employed in the synthesis of a heterogeneous copper complex on reduced graphene oxide. The resulting copper composite was characterized by SEM, TEM, XPS and energy dispersive x-ray spectroscopy (EDX). This supported copper catalyst containing unsym. triazolylnaphthyridinylpyridine (only 0.1 mol%) showed excellent catalytic activity in water with good recyclability. Various functionalized quinoline derivatives were successfully synthesized in high yields through the green strategy in water. Other heterocyclic compounds, such as pyridine, 2-(pyridin-2-yl)quinoline, 1,8-naphthyridine, 5,6-dihydronaphtho[1,2-b][1,8]naphthyridine and 2-(pyridin-2-yl)-1,8-naphthyridine derivatives, were achieved in water with >80% yields. Mechanism studies revealed that this transformation occurs via dehydrogenation, condensation, and transfer hydrogenation and dehydrogenation processes which was supported by a deuterium labeling experiment

Green Chemistry published new progress about Catalysts. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Recommanded Product: (2-Aminophenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chaudhari, Chandan; Sato, Katsutoshi; Ogura, Yuta; Miayahara, Shin-Ichiro; Nagaoka, Katsutoshi published the artcile< Pr2O3 Supported Nano-layered Ruthenium Catalyzed Acceptorless Dehydrogenative Synthesis of 2-Substituted Quinolines and 1,8-Naphthyridines from 2-Aminoaryl Alcohols and Ketones>, Quality Control of 5344-90-1, the main research area is quinoline naphthyridine preparation; aminoaryl alc ketone dehydrogenation ruthenium nanocatalyst.

Pr2O3 supported Ru nanolayers and Ru nanoparticles catalysts were examined for the synthesis of quinolines I (R = Me, Ph, pyridin-3-yl, etc.; R1 = H, Me; RR1 = -(CH2)4-). The Ru nanolayer was most active catalyst and showed a broad substrate scope. Structure-activity relationship demonstrated that the metallic state and morphol. of Ru as well as the basic site of Pr2O3 were indispensable factors of this catalytic system.

ChemCatChem published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent) (aryl). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Quality Control of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ozyilmaz, Ali Tuncay; Ozgen, Begum; Celik, Cumali published the artcile< Poly(o-aminobenzyl alcohol) films with and without organic compound on AISI 316 surface; synthesis and the corrosion performances>, Synthetic Route of 5344-90-1, the main research area is aminobenzyl alc organic compound corrosion performance.

In this work, we obtained the anticorrosive properties of polymer films (SS/PABA and SS/PABAORG) synthesized on stainless steel surface by adding an organic substance to aniline derived oaminobenzyl alc. monomer synthesis medium. Firstly, we prepared the polymer coating bath by dissolving 0.15 M o -aminobenzyl alc. monomer in the electrolyte solvent containing acetonitrile and 0.15 M LiClO4. From this bath, poly (o-aminobenzyl alc.) (PABA) film was synthesized in 30 segments by cyclic voltammetry (CV) technique at a scanning rate of 50 mV/s at a potential range of -0.20/1.80 V on the AISI 316 (SS) working electrode in contrast to the platinum electrode. For the synthesis of organic structure doped polymer film (PABA-ORG), we repeated the same synthesis process by dissolving C21H27NO2(k) (ORG) at low concentration in the same bath. We investigated the corrosion performances of bare SS, SS/PABA, and SS/PABA-ORG substrates, using open circuit potential – time, anodic polarization, and AC impedance techniques in the solution of corrosion study. As a result, we observed that the organic additive added to the synthesis medium caused changes in the synthesis behavior of PABA. Corrosion performance tests showed that PABA and PABA-ORG films increased the corrosion protection performance of the SS electrode, and we observed a reduction of the corrosion rate of the SS electrode.

Journal of the Turkish Chemical Society, Section A: Chemistry published new progress about Anodic polarization. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Synthetic Route of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sankar, Velayudham; Kathiresan, Murugavel; Sivakumar, Bitragunta; Mannathan, Subramaniyan published the artcile< Zinc-Catalyzed N-Alkylation of Aromatic Amines with Alcohols: A Ligand-Free Approach>, Product Details of C7H9NO, the main research area is alkyl amine preparation; amine alc alkylation zinc catalyst.

An efficient zinc-catalyzed N-alkylation reaction of aromatic amines was achieved using aliphatic, aromatic and heteroaromatic alcs. as the alkylating reagent. A variety of aniline derivatives, including heteroaromatic amines, underwent the N-alkylation reaction and furnished N-alkyl amines in good to excellent yields. The application of reaction was also further demonstrated by the synthesis of 2-phenylquinoline from acetophenone and 2-aminobenzyl alc. Deuterium labeling experiments showed that the reaction proceeded via a borrowing hydrogen process.

Advanced Synthesis & Catalysis published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Product Details of C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wan, Xiao-Min; Liu, Zi-Lin; Liu, Wan-Qing; Cao, Xiao-Niu; Zhu, Xinju; Zhao, Xue-Mei; Song, Bing; Hao, Xin-Qi; Liu, Guoji published the artcile< NNN pincer Ru(II)-catalyzed dehydrogenative coupling of 2-aminoarylmethanols with nitriles for the construction of quinazolines>, Name: (2-Aminophenyl)methanol, the main research area is aminobenzyl alc nitrile ruthenium catalyst oxidative coupling reaction; quinazoline preparation green chem.

An efficient NNN pincer Ru(II)-catalyzed preparation of quinazolines via acceptorless dehydrogenative strategy was developed. Under the optimized conditions, a broad range of substituted o-aminobenzyl alcs. and (hetero)aryl or alkyl nitriles were well tolerated to afford various 2-substituted quinazolines in high yields. Subsequently, a set of control experiments was performed to elucidate the reaction mechanism, which underwent alc. oxidation, nitrile hydration and cyclocondensation steps. This protocol was featured with several advantages, such as environmental benignity, operational simplicity, broad substrate scope (compatible with aliphatic nitriles, up to 87% yield) and short reaction time (mostly in 2 h).

Tetrahedron published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Name: (2-Aminophenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Huo, Shuaicong; Kong, Siqi; Zeng, Guang; Feng, Qi; Hao, Zhiqiang; Han, Zhangang; Lin, Jin; Lu, Guo-Liang published the artcile< Efficient access to quinolines and quinazolines by ruthenium complexes catalyzed acceptorless dehydrogenative coupling of 2-aminoarylmethanols with ketones and nitriles>, Safety of (2-Aminophenyl)methanol, the main research area is quinoline preparation; quinazoline preparation; ketone aminoarylmethanol dehydrogenative coupling reaction ruthenium catalyst; nitrile aminoarylmethanol dehydrogenative coupling reaction ruthenium catalyst.

Treatment of N,N,O-tridentate pyrazolyl-pyridinyl-alc. ligands, I (R = H, Me; R1 = H, Me, Ph; R2 = Me, Ph) with RuCl3·xH2O in refluxing EtOH afforded the corresponding Ru(III) complexes II, as chlorides, which were well characterized by IR, HR-MS and X-ray single crystal structural determination These Ru complexes II showed similarly high catalytic performance for both dehydrogenative couplings of 2-aminoarylmethanols [2-NH2-3-R3-5-R4C6H2CH2OH (R3 = H, Me, Br; R4 = H, F, Cl, Br) and 3-amino-3-phenyl-1-propanol] with ketones [R5C(O)CH3 (R5 = Ph, pyridin-3-yl, thiophen-2-yl, etc.), cycloheptanone and 1,2,3,4-tetrahydronaphthalen-1-one] and nitriles R6CN (R6 = Ph, 3-bromophenyl, thien-2-yl, etc.), giving the quinolines III, IV, V and 2,6-diphenylpyridine and quinazolines VI in good to excellent yields. This protocol provides an atom-economical and sustainable route to access various structurally important quinolines III, IV, V and 2,6-diphenylpyridine and quinazolines VI derivatives by using phosphine-free ligand based Ru catalysts II.

Molecular Catalysis published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Safety of (2-Aminophenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Arslan, Burcu; Gulcemal, Suleyman published the artcile< α-Alkylation of arylacetonitriles with primary alcohols catalyzed by backbone modified N-heterocyclic carbene iridium(I) complexes>, Computed Properties of 5344-90-1, the main research area is nitrogen heterocyclic carbene iridium complex preparation; aryl arylpropanenitrile preparation; arylquinolin amines preparation; arylacetonitrile alc alpha alkylation catalyst nitrogen heterocyclic carbene iridium.

A series of backbone-modified N-heterocyclic carbene (NHC) complexes of iridium(I) I [Ar = 4-MeOC6H4; Y = X = Ph, 4-MeOC6H4; YX = HC=CHCH=CH] had been synthesized and characterized. The electronic properties of the NHC ligands had been assessed by comparison of the IR carbonyl stretching frequencies of the in situ prepared [IrCl(CO)2(NHC)] complexes in CH2Cl2. These new complexes I [Ar = Ph, 4-CF3C6H4, 4-MeOC6H4; Y = X = H], together with previously prepared I [Ar = 4-MeOC6H4; Y = X = Ph, 4-MeOC6H4; YX = HC=CHCH=CH], were applied as catalysts for the α-alkylation of arylacetonitriles with an equimolar amount of primary alcs. or 2-aminobenzyl alc. The catalytic activities of these complexes I [Ar = Ph, 4-CF3C6H4, 4-MeOC6H4; Y = X = H, Ph, 4-MeOC6H4; YX = HC=CHCH=CH] could be controlled by modifying the N-substituents and backbone of the NHC ligands. The NHC-IrI complex I [Ar = Y = X = 4-MeOC6H4] bearing 4-methoxybenzyl substituents on the N-atoms and 4-methoxyphenyl groups at the 4,5-positions of imidazole exhibited the highest catalytic activity in the α-alkylation of arylacetonitriles with primary alcs. Various α-alkylated nitriles Ar1CH(CN)CH2Ar2 [Ar1 = Ph, 4-MeC6H4, 4-MeOC6H4, etc.; Ar2 = Ph, 2-pyridyl, 4-MeC6H4, etc.] and aminoquinolines II [R = H, Cl, Br, Me, OMe] were obtained in high yields through a borrowing hydrogen pathway by using 0.1 mol% I [Ar = Y = X = 4-MeOC6H4] and a catalytic amount of KOH (5 mol%) under an air atm. within significantly short reaction times.

Dalton Transactions published new progress about Acetonitriles Role: RCT (Reactant), RACT (Reactant or Reagent) (aryl). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Computed Properties of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gholinejad, Mohammad; Oftadeh, Erfan; Shojafar, Mohammad; Sansano, Jose M.; Lipshutz, Bruce H. published the artcile< Synergistic Effects of ppm Levels of Palladium on Natural Clinochlore for Reduction of Nitroarenes>, COA of Formula: C7H9NO, the main research area is aryl amine preparation green chem; nitroarene reduction pyridyltriazole clinochlore palladium nanocatalyst; clay; nitro compounds; palladium; reduction; synergistic effects.

The modified naturally occurring clay clinochlore with ppm amounts of palladium that leads to a new and very effective reagent for the reduction of numerous aromatic nitro species RNO2 (R = H3CC(O)NHC6H4, naphthalen-1-yl, pyridin-2-yl, etc.) has been augmented. When palladium nanoparticles are supported on pyridyltriazole-modified clinochlore, iron within clinochlore acts synergistically with palladium to catalyze the reduction of a wide variety of nitroarenes at room temperature in aqueous media. Based on E-factor calculations, the catalyst system is found to be in line with green chem. standards and can be recycled up to five times.

ChemSusChem published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, COA of Formula: C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Shanshan; Wang, Zheng; Cao, Qianrong; Yue, Erlin; Liu, Qingbin; Ma, Yanping; Liang, Tongling; Sun, Wen-Hua published the artcile< Aza-crown compounds synthesised by the self-condensation of 2-amino-benzyl alcohol over a pincer ruthenium catalyst and applied in the transfer hydrogenation of ketones>, Quality Control of 5344-90-1, the main research area is aminobenzyl alc pincer ruthenium catalyst self condensation; aza crown compound preparation; alkyl aryl ketone transfer hydrogenation iron catalyst; aralkyl alc preparation.

A well-defined PNN-Ru catalyst was revisited to self-condense 2-aminobenzyl alc. formed a series of novel aza-crown compounds All aza-crown compounds were separated and determined by NMR, IR, and ESI-MS spectroscopy as well as X-ray crystallog., indicated the saddle structure of aza-12-crown-3 and the twisted 1,3-alternate conformation structure of aza-20-crown-5. These aza-crown compounds was explored to study ferric initiation of transfer hydrogenation (TH) of ketones into their corresponding secondary alcs. in the presence of 2-propanol with a basic t-BuOK solution, achieving a high conversion (up to 95%) by a ferric complex with aza-16-crown-4 in a low loading (0.05 mol%).

Dalton Transactions published new progress about Alkyl aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Quality Control of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts