Category: 5344-90-1

Gupta, Shivangi; Maji, Ankur; Panja, Dibyajyoti; Halder, Mita; Kundu, Sabuj published the artcile< CuO NPs catalyzed synthesis of quinolines, pyridines, and pyrroles via dehydrogenative coupling strategy>, Product Details of C7H9NO, the main research area is hydroxymethyl aniline ketone copper nanocatalyst oxidative coupling reaction; quinoline preparation; hydroxypropanamine ketone copper nanocatalyst oxidative coupling reaction; pyridine preparation; hydroxyethanamine ketone copper nanocatalyst oxidative coupling reaction; pyrrole preparation.

Copper oxide nanoparticles catalyzed efficient synthesis of quinolines, pyridines, and pyrroles via alc. dehydrogenative coupling strategy are reported. Employing this catalytic system, various functionalized quinolines, pyridines, and pyrroles were synthesized efficiently from different amino alcs. with a diverse range of ketones. A number of control experiments were performed to shed light on the mechanism. This catalyst was recycled up to 6th run and notably, no significant loss was observed in its catalytic activity.

Journal of Catalysis published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Product Details of C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xu, Jingxiu; Chen, Qingmao; Luo, Zhigao; Tang, Xiaodong; Zhao, Jinwu published the artcile< N-Heterocyclic carbene copper catalyzed quinoline synthesis from 2-aminobenzyl alcohols and ketones using DMSO as an oxidant at room temperature>, Product Details of C7H9NO, the main research area is quinoline preparation; aminobenzyl alc Friedlander reaction ketone heterocyclic carbene catalyst.

A facile and practical process for the synthesis of quinolines through an N-heterocyclic carbene copper catalyzed indirect Friedlander reaction from 2-aminobenzyl alc. and aryl ketones using DMSO as an oxidant at room temperature is reported. The quinolines, e.g., I (R1 = 4-MeC6H4, 2-ClC6H4, 3-thienyl, etc., R2 = H; R1 = Ph, R2 = Me), were synthesized in acceptable yields.

RSC Advances published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent) (amino). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Product Details of C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Jinli; Chen, Ling; Dong, Yibo; Yang, Jinchen; Wu, Yangjie published the artcile< A Cu2O/TBAB-promoted approach to synthesize heteroaromatic 2-amines via one-pot cyclization of aryl isothiocyanates with ortho-substituted amines in water>, Application of C7H9NO, the main research area is aryl isothiocyanate amine copper catalyst desulfurization dehydrogenative cyclization; heteroaromatic amine preparation green chem.

An efficient approach to synthesize heteroaromatic 2-amines from one-pot desulfurization/dehydrogenative cyclization of aryl isothiocyanates with ortho-substituted amines in water was developed. This approach tolerated a wide range of functional groups on the aromatic ring, providing a practical and environment-friendly process to synthesize heteroaromatic 2-amines in moderate to excellent yields. A plausible mechanism was proposed and the role of TBAB and Cu2O in the present strategy was suggested with the help of ESI mass spectrometry.

Organic & Biomolecular Chemistry published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application of C7H9NO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Genc, Sertac; Gulcemal, Suleyman; Gunnaz, Salih; Cetinkaya, Bekir; Gulcemal, Derya published the artcile< Synthesis of α-Alkylated Ketones via Selective Epoxide Opening/Alkylation Reactions with Primary Alcohols>, Category: alcohols-buliding-blocks, the main research area is ketone alkyl preparation regioselective; alc primary epoxide opening alkylation reaction NHC iridium catalyst.

A new method for converting terminal epoxides I (R = Ph, naphthalen-2-yl, decyl, etc.) and primary alcs. R1CH2OH (R1 = hexyl, 2-aminophenyl, thiophen-2-yl, 3-ferrocenyl, etc.) into α-alkylated ketones RC(O)(CH2)2R1, 3,3′-(1,4-phenylene)bis(1-phenylpropan-1-one) and 2-phenylquinoline under borrowing hydrogen conditions is reported. The procedure involves a one-pot epoxide ring opening and alkylation via primary alcs. in the presence of an N-heterocyclic carbene iridium(I) catalyst, under aerobic conditions, with water as the side product.

Organic Letters published new progress about Alkylation catalysts, regioselective. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Elavarasan, Samaraj; Bhaumik, Asim; Sasidharan, Manickam published the artcile< An Efficient Mesoporous Cu-Organic Nanorod for Friedlaender Synthesis of Quinoline and Click Reactions>, Recommanded Product: (2-Aminophenyl)methanol, the main research area is hierarchical mesoporous organic polymer copper complex preparation surface area; aminobenzyl alc arylketone heterogeneous catalyst Friedlaender synthesis green chem; phenylquinoline preparation; benzylamine heterogeneous catalyst aerobic oxidative dehydrogenation green chem; arylalkyne azide benzylhalide heterogeneous catalyst regioselective click green chem.

A triazine functional hierarchical mesoporous organic polymer (HMOP) with nanorod morphol. together with large BET surface area ∼1218 m2g-1, huge pore volume&γτ”” ;6 mLg-1 and dual micro/mesopore architectures. Subsequent Cu-coordination with nitrogen atoms of the HMOP provided a robust catalyst (Cu-HMOP) to accomplish multi-step cascade reactions for preparation of N-heterocycles by different routes. For instance, the Cu-HMOP efficiently catalyzed one-pot sequential multi-step oxidative dehydrogenative coupling of 2-aminobenzyl alc. with diverse aromatic ketones to afford corresponding quinolines in excellent isolated yields (up to 97%). Secondly, the present catalyst exhibited good aerobic oxidative dehydrogenation activity of amines to imines. Thirdly, for “”click”” reaction involving azides-alkynes, the Cu-HMOP produced quant. yield for 1,4-disubstituted 1,2,3-triazole derivatives at room temperature using water as solvent. Verification of active metal leaching by a hot filtration test as well as reusability of the retrieved Cu-HMOP catalysts showed a consistent activity in the multi-component quinoline synthesis as model reaction.

ChemCatChem published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Recommanded Product: (2-Aminophenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Donthireddy, S. N. R.; Mathoor Illam, Praseetha; Rit, Arnab published the artcile< Ruthenium(II) Complexes of Heteroditopic N-Heterocyclic Carbene Ligands: Efficient Catalysts for C-N Bond Formation via a Hydrogen-Borrowing Strategy under Solvent-Free Conditions>, Electric Literature of 5344-90-1, the main research area is ruthenium imidazolylidene triazolylidene complex preparation crystal structure benzylation catalyst; crystal structure ruthenium imidazolylidene triazolylidene complex; mol structure ruthenium imidazolylidene triazolylidene complex; benzyl alc coupling reaction benzylation aniline derivative carbeneruthenium catalyst; quinoline derivative preparation.

Both imidazol-2-ylidene (ImNHC) and 1,2,3-triazol-5-ylidene (tzNHC) have evolved to be elite groups of N-heterocyclic carbene (NHC) ligands for homogeneous catalysis. To develop efficient Ru(II)-based catalysts incorporating these ligands for C-N bond-forming reactions via H-borrowing methodol., the authors used chelating ligands integrated with ImNHC and mesoionic tzNHC donors connected via a CH2 spacer with a diverse triazole backbone. The synthesized Ru(II) complexes 3 are highly efficient for C-N bond formation across a wide range of primary amine and alc. substrates under solvent-free conditions, and among all of the complexes studied here, catalyst 3a with a mesityl substituent displayed maximum activity. Catalyst 3a is also effective for the selective mono-N-methylation of various anilines using MeOH as a coupling partner, known to be relatively more difficult than other alcs. Also, complex 3a also delivers various substituted quinolines successfully via the reaction of 2-aminobenzyl alc. with several secondary alcs. Importantly, catalyst 3a exhibited the highest activity among the reported Ru(II) complexes for both the N-benzylation of aniline [achieving a turnover number (TON) of 50000] and the realization of quinoline 8a by reacting 2-aminobenzyl alc. with 2-phenylethanol (attaining a TON of 30000). The significance of electronic tuning in the Ru(II) complexes of chelating ligands featuring a combination of ImNHC and tzNHC donors with various triazole backbones is demonstrated by applying them in diverse C-N bond-forming reactions via a H-borrowing strategy. Notably, the Ru(II) complex 3a having an N-mesityl substituent displayed the highest activity among known Ru(II) complexes for both the N-benzylation of aniline [a turnover number (TON) of 50000] and the synthesis of quinoline via the reaction of 2-aminobenzyl alc. with 2-phenylethanol (a TON of 30000).

Inorganic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Electric Literature of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Adhikary, Subhasis D.; Mandal, Debaprasad published the artcile< Polyoxometalate catalyzed imine synthesis: Investigation of mechanistic pathways>, Application In Synthesis of 5344-90-1, the main research area is preparation crystal structure zinc tungsten polyoxometalate complex; thermal decomposition zinc tungsten polyoxometalate complex; zinc tungsten polyoxometalate complex catalyst imine synthesis; imine preparation.

The syntheses of imines by oxidative coupling of primary alcs. and amines were achieved by using 2 mol% polyoxometalate (POM) Na12[WZn3(H2O)2(ZnW9O34)2] (Zn-WZn3) catalyst in the presence of t-BuOK and di-oxygen with excellent conversion (up to 100%) and selectivity (up to 100%). Non-noble metal-based POM catalyst in the presence of base represents a new reaction protocol for the selective synthesis of imine from both aromatic and aliphatic primary amines with functional group tolerance. Control experiment shows the formation of di-oxygen bind Zn-WZn3 activated species. The electron-d. of POM is mostly situated on the surface oxygen atoms of W-O-W bonds which can engage the alc. OH group and helps for the imine selectivity in the second step of imine synthesis.

Tetrahedron published new progress about Crystal structure. 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Application In Synthesis of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Putta, V. P. Rama Kishore; Gujjarappa, Raghuram; Tyagi, Ujjawal; Pujar, Prasad P.; Malakar, Chandi C. published the artcile< A metal- and base-free domino protocol for the synthesis of 1,3-benzoselenazines, 1,3-benzothiazines and related scaffolds>, Category: alcohols-buliding-blocks, the main research area is arylthiazinone preparation; benzoselenazine preparation; diaryldiazocine dione preparation; benzothiazine preparation.

Efficient protocols have been described for the synthesis of 1,3-benzoselenazines, 1,3-benzothiazines, 2-arylthiazin-4-ones and diaryl[b,f][1,5]diazocine-6,12(5H,11H)-diones. These transformations were successfully driven towards product formation under mild acid catalyzed reaction conditions at room temperature using 2-aminoaryl/hetero-aryl alkyl alcs. and amides as substrates. The merits of the present methods also rely on the easy access of rarely explored bioactive scaffolds like 1,3-benzoselenazine derivatives, for which well-documented methods are rarely known in the literature. A broad range of substrates with both electron-rich and electron-deficient groups were well-tolerated under the developed conditions to furnish the desired products in yields up to 98%. The scope of the devised method was not only restricted to the synthesis of 1,3-benzoselenazines, but it was further extended towards the synthesis of 1,3-benzothiazines, 1,3-benzothiazinones and the corresponding eight-membered N-heterocycles such as diaryl[b,f][1,5]diazocine-6,12(5H,11H)-diones.

Organic & Biomolecular Chemistry published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent) (amino). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Shi-Qi; Cui, Yao; Guo, Bin; Young, David J.; Xu, Ze; Li, Hong-Xi published the artcile< Efficient synthesis of quinazolines by the iron-catalyzed acceptor-less dehydrogenative coupling of (2-aminophenyl)methanols and benzamides>, Name: (2-Aminophenyl)methanol, the main research area is preparation quinazolines iron catalyzed acceptorless dehydrogenative coupling; aminophenylmethanols benzamides heterocyclization.

The acceptor-less dehydrogenation coupling (ADC) of (2-aminophenyl)methanols with benzamides was achieved with catalytic FeCl2·4H2O in an efficient synthesis of quinazolines. This simple catalytic system is atom-economical, environmentally benign and suited to a variety of substrates.

Tetrahedron published new progress about Benzamides Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Name: (2-Aminophenyl)methanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cao, Fei; Mao, Anruo; Yang, Bobin; Ge, Chenyang; Wang, Dawei published the artcile< The preparation of a Co@C3N4 catalyst and applications in the synthesis of quinolines from 2-aminobenzyl alcohols with ketones>, Electric Literature of 5344-90-1, the main research area is cobalt doped carbon nitride catalyst quinoline synthesis aminobenzenemethanol ketone.

An unsym. diphenylphosphino-pyridinyl-triazole ligand was synthesized and characterized through IR, NMR and MS and the corresponding earth-abundant metal complex (cobalt) was prepared Considering energy consumption and environmental friendliness, it is necessary to turn this diphenylphosphino-pyridinyl-triazole cobalt complex into a recyclable catalyst, which could easily be reused. Therefore, a heterogeneous catalyst was synthesized through Co-doping of C3N4, and the Co-nanoparticles on C3N4 revealed high catalytic activity for the synthesis of quinolines with good recovery performance.

New Journal of Chemistry published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 5344-90-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H9NO, Electric Literature of 5344-90-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts