Category: 534-03-2

Synthetic Route of C3H9NO2In 2019 ,《Towards mechanical robust yet self-healing polyurethane elastomers via combination of dynamic main chain and dangling quadruple hydrogen bonds》 was published in Polymer. The article was written by Hu, Jin; Mo, Ruibin; Jiang, Xiang; Sheng, Xinxin; Zhang, Xinya. The article contains the following contents:

One of the greatest challenges of robust self-healing materials is the confliction between high chain mobility for self-healing and a stable structure for mech. strength. Herein, dangling 2-ureido-4[1H]-pyrimidione (UPy)-functionalized side groups were introduced into the hard segments of thermoplastic polyurethane (TPU) elastomers, where embedded the dynamic disulfide bonds in the main chain. The strong quadruple H-bonding interaction between UPy side groups acts as supramol. crosslinkers enabling the TPU elastomer to have improved mech. properties (tensile strength up to 25 MPa and toughness ∼100 MJ m-3), and simultaneously the plasticizer effect of dangling side chain endows it with efficient healing ability at elevated temperatures (80-100 °C) comparable to its linear analogs. This strategy shows great potential in designing robust self-healing TPU elastomer employing weak dynamic covalent bonds, with wide promising applications as wearable electronics, coatings and adhesives. In addition to this study using 2-Aminopropane-1,3-diol, there are many other studies that have used 2-Aminopropane-1,3-diol(cas: 534-03-2Synthetic Route of C3H9NO2) was used in this study.

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).Synthetic Route of C3H9NO2

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Category: alcohols-buliding-blocksIn 2022 ,《One-pot synthesis of hydroxyl terminated hyperbranched semi-aromatic Poly(ester-imide)s》 appeared in Polymer. The author of the article were Zhou, Jiajun; Li, Mao; Wu, Jiadong; Zhang, Chongyin; He, Zidong; Xiao, Yan; Tong, Gangsheng; Zhu, Xinyuan. The article conveys some information:

A new kind of hyperbranched semi-aromatic poly(ester-imide)s with hydroxyl terminated groups has been prepared from com. available 1,2,4-benzenetricarboxylic anhydride (TMA) as the AA’-type aromatic monomer and 3-amino-1,2-propanediol (3APPD), 2-amino-1,3-propanediol (2APPD), N,N-bis(2-hydroxyethyl)ethylenediamine (BHED) as CB2-type aliphatic monomers via a simple one-pot melting polymerization method. The effects of synthesis conditions on the structures and properties of the products were investigated in detail. The combination of FTIR, 1H NMR, 2D NMR, MALDI-FTICR-MS and model reactions have been used to characterize the structures of the obtained polymers. As assessed using thermal measurements, the obtained hyperbranched semi-aromatic poly(ester-imide)s possess low glass transition temperature (≤120°C) and high thermostability with an onset decomposition temperature ranging from 355 to 420°C in nitrogen. The products possess abundant terminal hydroxyl functional groups. Hydroxyl values vary between 198 and 248 mg KOH/g depending on the particular precursors used to generate the polymers. The experimental part of the paper was very detailed, including the reaction process of 2-Aminopropane-1,3-diol(cas: 534-03-2Category: alcohols-buliding-blocks)

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Nitrous acid converts secondary amines (aliphatic or aromatic) to N-nitroso compounds (nitrosamines): R2NH + HNO2 → R2N―NO. Some nitrosamines are potent cancer-inducing substances, and their possible formation is a serious consideration when nitrites, which are salts of nitrous acid, are present in foods or pharmaceutical preparations. Tertiary amines give rise to nitrosamines more slowly; an alkyl group is eliminated as an aldehyde or ketone, along with nitrous oxide, N2O.Category: alcohols-buliding-blocks

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Rigo, Davide; Santos, Nadia Alessandra Carmo Dos; Perosa, Alvise; Selva, Maurizio published an article in 2021. The article was titled 《Concatenated batch and continuous flow procedures for the upgrading of glycerol-derived aminodiols via N-acetylation and acetalization reactions》, and you may find the article in Catalysts.Related Products of 534-03-2 The information in the text is summarized as follows:

An unprecedented two-step sequence was designed by combining batch and continuous flow (CF) protocols for the upgrading of two aminodiol regioisomers derived from glycerol, i.e., 3-amino-1,2-propanediol and 2-amino-1,3-propanediol (serinol). Under batch conditions, at 80-90°C, both substrates were quant. converted into the corresponding amides through a catalyst-free N-acetylation reaction mediated by an innocuous enol ester as isopropenyl acetate (iPAc). Thereafter, at 30-100°C and 1-10 atm, the amide derivatives underwent a selective CF-acetalisation in the presence of acetone and a solid acid catalyst, to afford the double-functionalized (amide-acetal) products. In the part of experimental materials, we found many familiar compounds, such as 2-Aminopropane-1,3-diol(cas: 534-03-2Related Products of 534-03-2)

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. To avoid the problem of multiple alkylation, methods have been devised for “blocking” substitution so that only one alkyl group is introduced. The Gabriel synthesis is one such method; it utilizes phthalimide, C6H4(CO)2NH, whose one acidic hydrogen atom has been removed upon the addition of a base such as KOH to form a salt.Related Products of 534-03-2

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Category: alcohols-buliding-blocksIn 2022 ,《Synthesis and Characterization of Alkyne-Functionalized Photo-Cross-Linkable Polyesters》 was published in ACS Omega. The article was written by Ma, Warrick; Ding, Xiaochu; Chen, Ying; Wang, Yadong. The article contains the following contents:

An alkyne-functionalized elastomer derived from sebacic acid, 1,3-propanediol, and alkyne-functionalized serinol is synthesized via melt condensation. A low-power UV lamp triggers the crosslinking rapidly via thiol-yne click chem. The crosslinking behavior is studied by photorheol. and NMR spectroscopy. The resultant elastomer possesses mech. properties similar to those of human soft tissues and exhibits in vitro degradability and good cytocompatibility. After reading the article, we found that the author used 2-Aminopropane-1,3-diol(cas: 534-03-2Category: alcohols-buliding-blocks)

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).Category: alcohols-buliding-blocks

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《Antitumor activity of new olivacine derivatives》 was published in Molecules in 2020. These research results belong to Piasny, Janusz; Wiatrak, Benita; Dobosz, Agnieszka; Tylinska, Beata; Gebarowski, Tomasz. HPLC of Formula: 534-03-2 The article mentions the following:

Olivacine is an alkaloid-containing pyridocarbazole structure. It is isolated from the bark of the evergreen timber tree, Aspidosperma olivaceum. Its well-documented anticancer activity led to the synthesis of new derivatives, which are semisynthetic and fully synthetic pyridocarbazoles. This study aimed to evaluate the potential antineoplastic activity of four newly synthesized olivacine derivatives Multidrug resistance is a common phenomenon causing failure in the chemotherapy of many tumors. It is mainly related to increased function of P-glycoprotein, an efflux pump removing cytostatic out of the cells. The cell lines used in the study were colorectal carcinoma cell lines: LoVo (doxorubicin-sensitive) and LoVo/DX (doxorubicin-resistant). The NHDF cell line was used to assess cell viability. First, the cells were incubated with olivacine derivatives In the next step, the following assays were performed: DCF-DA assay, MTT assay, rhodamine 123 assay, detection of apoptosis, proliferation inhibition-mitotic index. The tested compounds showed higher antineoplastic potential and lower toxicity than the reference compound ellipticine. The results indicate that the new olivacine derivatives are good candidates for future anticancer drugs. In addition to this study using 2-Aminopropane-1,3-diol, there are many other studies that have used 2-Aminopropane-1,3-diol(cas: 534-03-2HPLC of Formula: 534-03-2) was used in this study.

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.HPLC of Formula: 534-03-2

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In 2019,Polyhedron included an article by Abbas, Ghulam; Ibrahim, Masooma; Schmidt, Sebastian F. M.; Moreno-Pineda, Eufemio; Anson, Christopher E.; Powell, Annie K.. Recommanded Product: 534-03-2. The article was titled 《Synthesis of five isostructural tetranuclear Fe2Ln2 (Ln = Gd, Tb, Dy, Ho, Er) complexes with an “”inverse butterfly”” core》. The information in the text is summarized as follows:

A 1-pot synthesis leading to in situ ligand formation enabled the preparation of five isostructural tetranuclear Fe2Ln2 coordination clusters [Fe2Ln2(μ4L)2(mpm)2(piv)2(N3)3.5(Cl)0.5], where H2L is 2-((pyridin-2-ylmethylene)amino)propan-1,3-diol, Hmpm is methoxy(2-pyridinyl)methanol, piv is pivalate and Ln = Gd (1), Tb (2), Dy (3), Ho (4), Er (5). These show an unprecedented core structure. The coordination compounds were fully characterized by IR spectroscopy, elemental anal., powder x-ray diffraction and single crystal X-ray diffraction. Magnetic measurements indicate intramol. antiferromagnetic and ferromagnetic interactions. The finding is important in developing synthetic strategies for the preparation of new mol. based magnetic materials. The experimental part of the paper was very detailed, including the reaction process of 2-Aminopropane-1,3-diol(cas: 534-03-2Recommanded Product: 534-03-2)

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Recommanded Product: 534-03-2

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Sheng, Rui; Zhang, Yang; Kang, Jingjing; Tang, Yakun; Zhu, Caixia; Liu, Lang published their research in ChemistrySelect in 2021. The article was titled 《Nanorod-Like Polymer Adsorbents with Intermediate Dihydroxy Functional Groups for Efficient Boron Removal》.Computed Properties of C3H9NO2 The article contains the following contents:

Intermediate dihydroxy (m-diol) compounds act as grafting groups and one-dimensional Poly(VBC-DVB) copolymer as supporter, the short rod-like adsorbents were prepared by grafting trihydroxymethyl aminomethane (TRIS) and 2-amino-1, 3-propanediol (APD) on the polymer Poly(VBC-DVB). The as-synthesized adsorbents exhibit excellent boron adsorption capacities in neutral and weakly alk. solutions because of the formation of stable six-membered ring complexes. The novel boron adsorbents have potential applications in boron removal. In the part of experimental materials, we found many familiar compounds, such as 2-Aminopropane-1,3-diol(cas: 534-03-2Computed Properties of C3H9NO2)

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Amines characteristically form salts with acids; a hydrogen ion, H+, adds to the nitrogen. With the strong mineral acids (e.g., H2SO4, HNO3, and HCl), the reaction is vigorous. Salt formation is instantly reversed by strong bases such as NaOH. Neutral electrophiles (compounds attracted to regions of negative charge) also react with amines; alkyl halides (R′X) and analogous alkylating agents are important examples of electrophilic reagents.Computed Properties of C3H9NO2

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Chen, Ye; Zhang, Pengfei; Liu, Shan; Pahovnik, David; Zagar, Ema; Zhao, Junpeng; Zhang, Guangzhao published their research in ACS Macro Letters in 2021. The article was titled 《Noncovalent Protection for Direct Synthesis of α-Amino-ω-hydroxyl Poly(ethylene oxide)》.Formula: C3H9NO2 The article contains the following contents:

The synthesis of poly(ethylene oxide) (PEO) with amino end group, a key functionality for PEGylation, is a long-standing challenge. Multistep routes based on postmodification or covalent protection have been adopted to circumvent ethoxylation of the amino group by ethylene oxide (EO). Here, we report a noncovalent protection strategy for one-step synthesis of PEO amine. An amino (di)alc. is mixed with a small amount of mild phosphazene base and excess triethylborane (Et3B) before addition of EO. The complexation of the amino group with Et3B guarantees that polymerization of EO occurs selectively from the hydroxyl group through the bicomponent metal-free catalysis. Simply by precipitation in di-Et ether, the protective Et3B as well as the catalyst can be removed to afford α-amino-ω-hydroxyl PEO with controlled molar mass, low dispersity, and complete end functionality. The effect of initiator structure and retention of Et3B on the storage (oxidative) stability of PEO amine is also revealed. In the experiment, the researchers used many compounds, for example, 2-Aminopropane-1,3-diol(cas: 534-03-2Formula: C3H9NO2)

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).Formula: C3H9NO2

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The author of 《A self-powered triboelectric nanosensor for detecting the corrosion state of magnesium treated by micro-arc oxidation》 were Zhai, Yong-Mei; Li, Wei; Chen, Min-Fang; Li, Yan-Kun; Wang, Qi; Wang, Yan-Song. And the article was published in RSC Advances in 2019. Application In Synthesis of 2-Aminopropane-1,3-diol The author mentioned the following in the article:

Magnesium (Mg) is frequently used as a biocompatible implantable material in the human body, but real-time detection of its corrosion state is not well understood. Fortunately, previous studies of triboelec. nanogenerators (TENG) as self-driven sensors in many fields have proposed solutions for this problem. In this work, Mg-based TENG was prepared as a self-driven sensor to detect the corresponding corrosion state of Mg treated by micro-arc oxidation (MAO-Mg). Mg-based sheets and polydimethylsiloxane (PDMS) film were used as triboelec. materials. The output of TENG was optimal under 350 V-800 Hz micro-arc oxidation (MAO) treatment of Mg, and the Voc, Isc and Qsc were 48.5 V, 35.3μA and 44.2 nC, which were resp. 2.42, 3.42 and 3.27 times that of the untreated devices. Moreover, a linear relationship was found in simulated body fluid (SBF) immersion tests, showing that the rates of decrease in Isc and Voc were resp. 3.48 and 2.74 times the weight reduction rates of MAO-Mg sheets, indicating that our sensors successfully detected the corrosion of MAO-Mg. This work will lay a preliminary foundation for real-time detection of Mg as an implant in the human body (as do other implantable materials), and demonstrates a potential new application for TENG in the biomedical field. The experimental part of the paper was very detailed, including the reaction process of 2-Aminopropane-1,3-diol(cas: 534-03-2Application In Synthesis of 2-Aminopropane-1,3-diol)

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Application In Synthesis of 2-Aminopropane-1,3-diol

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《Focus on chemistry of the 10-Dioxane-nido-7,8-dicarba-undecahydrido undecaborate Zwitterion; exceptionally easy abstraction of hydrogen bridge and double-action pathways observed in ring cleavage reactions with OH- as Nucleophileã€?was published in Molecules in 2020. These research results belong to Bakardjiev, Mario; El Anwar, Suzan; Bavol, Dmytro; Ruzickova, Zdenka; Gruner, Bohumir. Electric Literature of C3H9NO2 The article mentions the following:

Ring cleavage of cyclic ether substituents attached to a boron cage via an oxonium oxygen atom are amongst the most versatile methods for conjoining boron closo-cages with organic functional groups. Here we focus on much less tackled chem. of the 11-vertex zwitterionic compound [10-(O-(CH2-CH2)2O)-nido-7,8-C2B9H11], which is the only known representative of cyclic ether substitution at nido-cages, and explore the scope for the use of this zwitterion 1 in reactions with various types of nucleophiles including bifunctional ones. Most of the nitrogen, oxygen, halogen, and sulfur nucleophiles studied react via nucleophilic substitution at the C1 atom of the dioxane ring, followed by its cleavage that produces six atom chain between the cage and the resp. organic moiety. We also report the differences in reactivity of this nido-cage system with the simplest oxygen nucleophile, i.e., OH-. With 11-vertex zwitterionic compound [10-(O-(CH2-CH2)2O)-nido-7,8-C2B9H11], reaction proceeds in two possible directions, either via typical ring cleavage, or by replacement of the whole dioxane ring with -OH at higher temperatures Furthermore, an easy deprotonation of the hydrogen bridge in 11-vertex zwitterionic compound [10-(O-(CH2-CH2)2O)-nido-7,8-C2B9H11] was observed that proceeds even in diluted aqueous KOH. We believe this knowledge can be further applied in the design of functional mols., materials, and drugs. The results came from multiple reactions, including the reaction of 2-Aminopropane-1,3-diol(cas: 534-03-2Electric Literature of C3H9NO2)

2-Aminopropane-1,3-diol(cas: 534-03-2) belongs to anime. Reduction of nitro compounds, RNO2, by hydrogen or other reducing agents produces primary amines cleanly (i.e., without a mixture of products), but the method is mostly used for aromatic amines because of the limited availability of aliphatic nitro compounds. Reduction of nitriles and oximes (R2C=NOH) also yields primary amines.Electric Literature of C3H9NO2

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