Category: 5333-42-6

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 5333-42-6, name is 2-octyldodecan-1-ol, molecular formula is C20H42O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. category: alcohols-buliding-blocks

Example 4 Preparation of 2-octyldodecyl phenylacetate To a 3-neck 1000 ml round-bottomed flask was added 2-octyl-1-dodecanol (240.0 g, 803.88 mmol, 1.0 equiv.), phenylacetic acid (142.28 g, 1045.0 mmol, 1.30 equiv.), toluene (240 ml) and p-toluenesulfonic acid monohydrate (1.5291 g, 8.0386 mmol, 0.010 equiv.) at room temperature. The resulting mixture was heated at reflux with stirring in an oil bath at 134 C. under a nitrogen atmosphere for 9 hours. The water produced in the reaction was collected in a Dean-Stark trap. The cooled mixture was diluted with hexanes, washed with dilute aqueous Na2CO3 solution, water, brine, dried (MgSO4), filtered, and concentrated in vacuo to afford a crude product. Excess solvent was further removed by heating the crude product with stirring in an oil bath under high vacuum for 3 hours to afford a light yellow liquid (330.0 g. 98%).

With the rapid development of chemical substances, we look forward to future research findings about 5333-42-6.

Reference:
Patent; ExxonMobil Research and Engineering Company; Ng, Man Kit; Oumar-Mahamat, Halou; Cheng, Hong; Blain, David A.; Cooper, Kathleen K.; Carey, James T.; Douglass, Michael R.; Kanga, Percy R.; Patil, Abhimanyu O.; Bodige, Satish; Lewis, Kyle G.; Hagemeister, Mark P.; (40 pag.)US2017/183595; (2017); A1;,
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Adding a certain compound to certain chemical reactions, such as: 5333-42-6, 2-octyldodecan-1-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 2-octyldodecan-1-ol, blongs to alcohols-buliding-blocks compound. Recommanded Product: 2-octyldodecan-1-ol

Take 0.1g (452g/mol, 0.22mmol)Diisobutyl 3,9-nonanedicarboxylate in a round bottom flask, adding 1.63g(298 g/mol, 5.5 mmol) of 2-octyldodecanol was heated to 100 C,Add 0.01 g (10 wt%) of dihydroxybutyl tin chloride to the reaction flask,The temperature was raised to 170 C, and the reaction was heated for 3 h, and the plate was tracked during the reaction.After the reaction, the reaction was cooled to room temperature and the temperature was raised to 180 C.Vacuum distillation,Distilling off excess 2-octyldodecanol which acts as both a solvent for the reaction and a reactantDry in vacuum. The resulting product was cooled to room temperature and dissolved in petroleum ether.The wet method was purified by silica gel column to obtain a yellow dye. The conversion was calculated to be 90%.

The synthetic route of 5333-42-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Shenzhen Guohua Optoelectric Technology Co., Ltd.; Shenzhen Guohua Optoelectric Institute; Zhou Guofu; Deng Yong; Li Shi; Ye Dechao; (8 pag.)CN109627802; (2019); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application of 5333-42-6 , The common heterocyclic compound, 5333-42-6, name is 2-octyldodecan-1-ol, molecular formula is C20H42O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General synthesis of beta-glycosides (amounts based on branched C24 disaccharide glycosides) A solution of 3.4 T beta-peracetate and.2.3 g 2-decyl-tetradecanol in 50 mL anhydrous dichloromethane was treated with 600 muL borontrifluoride dimethyletherate and kept at room temperature for about 5-48 h. The mixture was washed with aqueous sodium bicarbonate and dried over magnesium sulfate. After evaporation of the solvent, the acetylated glycolipid was purified by chromatography (hexane/ethyl acetate). The intermediate product was dissolved in 30-40 mL methanol and treated with a catalytic amount of sodium methoxide. After 30-60 min the catalyst was removed by treatment with amberlite IR 120 (H+) and the solvent was evaporated. Further purification of the anomer by chromatography on ion exchanging resin generally proofed to be unnecessary.

The synthetic route of 5333-42-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; UNIVERSITI MALAYA; PINTAS PTE LTD; WO2006/98699; (2006); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts