Category: 5333-42-6

Electric Literature of 5333-42-6, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 5333-42-6 as follows.

Example 13 Preparation of 2-octyldodecyl 2-(2-(2-methoxyethoxy)ethoxy)acetate To a 3-neck 1000 ml round-bottomed flask was added 2-octyl-1-dodecanol (220.00 g, 736.89 mmol, 1.0 equiv.), 2-(2-(2-methoxyethoxy)ethoxy)acetic acid (170.693 g, 957.95 mmol, 1.30 equiv.), toluene (200 ml) and p-toluenesulfonic acid monohydrate (1.4017 g, 7.3688 mmol, 0.010 equiv.) at room temperature. The resulting mixture was heated at reflux with stirring in an oil bath at 134 C. under a nitrogen atmosphere for 6 hours. The water produced in the reaction was collected in a Dean-Stark trap. The cooled mixture was diluted with diethyl ether, washed with dilute aqueous Na2CO3 solution, water, brine, dried (MgSO4), filtered, and concentrated in vacuo to afford a crude product. Excess solvent was further removed by heating the crude product with stirring in an oil bath under high vacuum for 2 hours to afford a clear light yellow liquid (319.67 g, 94%).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,5333-42-6, its application will become more common.

Reference:
Patent; ExxonMobil Research and Engineering Company; Ng, Man Kit; Oumar-Mahamat, Halou; Cheng, Hong; Blain, David A.; Cooper, Kathleen K.; Carey, James T.; Douglass, Michael R.; Kanga, Percy R.; Patil, Abhimanyu O.; Bodige, Satish; Lewis, Kyle G.; Hagemeister, Mark P.; (40 pag.)US2017/183595; (2017); A1;,
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Synthetic Route of 5333-42-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 5333-42-6, name is 2-octyldodecan-1-ol, molecular formula is C20H42O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

To a solution of 2-octyl-1-dodecanol (5.88 g, 19.7 mmol), triphenylphosphine (6.20 g, 23.6 mmol) and imidazole (1.61g, 23.6 mmol) in CH2Cl2 (40 mL) was slowly added bromine (3.78 g, 10.4 mmol) at 0 C, and the mixture was stirred at room temperature for 24 h. The reaction was then quenched with 3% Na2S2O3 aq. The product was extracted withhexane, and then the hexane layer was washed with brine. After drying the solution over MgSO4 followed by filtration,the filtrate was condensed under the reduced pressure. The crude product was purified by silica gel columnchromatography using hexane/CH2Cl2 (1/1, v/v) as an eluent to afford 1 as transparent oil (5.80 g, 82%). 1H NMR (300MHz, CDCl3, delta, ppm, 25 C): 3.44 (d, J=3.9 Hz, 2H, Br-CH2-CH), 1.64-1.53 (m, 1H, Br-CH2-CH), 1.44-1.17 (m,32H, -CH2-), 0.88 (t, J=5.1 Hz, 6H, -CH3). 13C NMR (75 MHz, CDCl3, delta, ppm, 25 C): 39.89, 39.65, 32.72-26.72(14 carbons), 22.86 (2 carbons), 14.28 (2 carbons). IR (NaCl), v (cm-1): 2924 (alkyl C-H).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 5333-42-6, 2-octyldodecan-1-ol.

Reference:
Article; Aoyagi, Koutarou; Shoji, Yu; Otsubo, Saika; Kawauchi, Susumu; Ueda, Mitsuru; Matsumoto, Hidetoshi; Higashihara, Tomoya; Bulletin of the Chemical Society of Japan; vol. 87; 10; (2014); p. 1083 – 1093;,
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Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 5333-42-6, name is 2-octyldodecan-1-ol. A new synthetic method of this compound is introduced below., COA of Formula: C20H42O

2-octyldodecyl thiophene-3-carboxylate (SI). A solution of thiophene-3-carboxylic acid (1, 5.126 g, 40 mmol) in 150 mL DCM was stirred at room temperature under N2. Then 4-Dimethylaminopyridine (1.466 g, 12 mmol), a DCM solution of Nu,Nu’-dicyclohexylcarbodiimide ( 9904 mg , 48 mmol ) and 2-octyldodecan-l-ol (2, 23.88 g, 80 mmol ) were added to the system. The reaction mixture was stirred for another 12 hours. 50 mL distilled water was added and the reaction mixture was filtered, diluted with hexane and washed with water and brine. The organic layer was dried over Na2S04, filtered and concentrated. Then the residue was purified with silica gel chromatography to provide pure product as transparent liquid (17.25 g, 92% yield). 1H NMR (400 MHz, CDC13) delta 8.08 (d, / = 1.7 Hz, 1H), 7.54 – 7.51 (m, 1H), 7.31 – 7.28 (m, 1H), 4.18 (d, / = 5.6 Hz, 2H), 1.74 (d, / = 4.4 Hz, 1H), 1.41 – 1.22 (m, 32H), 0.88 (t, / = 6.3 Hz, 6H). 13C NMR (101 MHz, CDC13) delta 163.13, 134.27, 132.57, 128.09, 126.07, 67.68, 37.63, 32.12, 32.11, 31.64, 30.15, 29.85, 29.80, 29.76, 29.55, 29.51, 26.96, 22.89, 22.88, 14.31. HRMS (MALDI+) Calcd for C25H4402S (M+): 408.3062, Found: 408.3080.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 5333-42-6, 2-octyldodecan-1-ol.

Reference:
Patent; THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY; YAN, He; LIU, Jing; (52 pag.)WO2017/223407; (2017); A1;,
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Related Products of 5333-42-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5333-42-6, name is 2-octyldodecan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

2-Octyl-l-dodecanol (5 g, 16.7 mmol) was taken in a 100 mL round bottomed flask, pyridiniumchlorochromate (10.8 g, 50.24 mmol) was added to it and the mixture was dissolved in anhydrous CH2C12 (120 mL). The reaction mixture was stirred at room temperature (27C) for 3 h and filtered through a short pad of silica gel to provide the required aldehyde as a colourless liquid. 4.68 g, Yield: 94%.1H NMR (400 MHz, CDC13) delta: 9.54 (d, / = 3.2 Hz, 1 H), 2.26 – 2.14 (m, 1 H), 1.68 – 1.53 (m, 2 H), 1.42 (dd, / = 14.2, 5.6 Hz, 2 H), 1.25 (broad s, 28 H), 0.87 (t, / = 6.8 Hz, 6 H); 13C NMR (100 MHz, CDC13) delta: 211.9, 182.8, 161.1, 77.3, 77.2, 76.7, 74.6, 72.1, 45.5, 42.8, 37.4, 34.0, 32.2, 31.9, 31.8, 29.7, (0101) 29.6, 29.6, 29.5, 29.5, 29.3, 29.3, 29.3, 29.1, 27.4, 25.6, 25.2, 23.9, 22.7, 14.1; MALDI-TOF (m/z): [M]+ calcd for C20H40O: 296.3079; found: 296.2517.

According to the analysis of related databases, 5333-42-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH; NITHYANANDAN, Jayaraj; ALAGUMALAI, Ananthan; FAIROOS, Munavvar; VELLIMALAI, Punitharasu; (47 pag.)WO2018/20518; (2018); A1;,
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Synthetic Route of 5333-42-6, Adding some certain compound to certain chemical reactions, such as: 5333-42-6, name is 2-octyldodecan-1-ol,molecular formula is C20H42O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 5333-42-6.

Into a 250 ml glass reactor fitted with an Argon purge was placed the hexanoic acid (23.2 grams, 0.2 moles), 2-octyl-1-dodecanol (29.9 grams, 0.1 moles) (Aldrich 97%) (the “C20-alcohol”, which is a Guerbet alcohol) and p-toluene sulfonic acid monohydrate (19 grams, 0.1 mole). The mixture above was purged with Argon at room temperature for one hour. The mixture was then heated to 100 C. under Argon purge for 18 hours. The mixture was then cooled to room temperature. The residue was then dissolved into 100 ml with ethyl acetate and placed into a separatory funnel. The ethyl acetate solution was extracted once with 100 ml of distilled water. The ethyl acetate layer was washed with 250 ml 10 wt % NaHCO3 aqueous solution followed by 250 ml saturated NaCl aqueous solution. The ethyl acetate solution was dried over MgSO4 and then filtered. The ethyl acetate was removed on the rotary evaporator from the solution. The residue from the rotary evaporator was placed on a Kugelrohr vacuum distillation apparatus where the ester was distilled. 1H NMR (CDCl13): delta3.96 (d, 2H, O-CH2-), 2.31 (d, 2H, O=C-CH2-), 1.61-1.26 (m, 39H, -CH2-), 0.80 (t, 9H, CH3). IR (cm-1): 2955, 2925, 2854, 1733, 1466, 1378, 1234, 1168, 1102, 722.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 5333-42-6, 2-octyldodecan-1-ol, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; ExxonMobil Chemical Patents Inc.; Patil, Abhimanyu O.; Lewis, Kyle G.; Bodige, Satish; Zushma, Stephen; US2019/62663; (2019); A1;,
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As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 5333-42-6, name is 2-octyldodecan-1-ol, molecular formula is C20H42O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Computed Properties of C20H42O

A 500-mL three-necked flask equipped with magnetic stirrer, septum, and thermometer was filled with argon. Triphenylphosphine (33.4 g, 0.127 mol, 1 equiv.) and 200 mL of anhydrous dichloromethane were placed into the flask. The solution was cooled to 0C, and 6.52 mL (20.34 g, 0.127 mol, 1 equiv.) of bromine was added dropwise so that the temperature of the reaction mix- ture was not higher 5C. After bromine addition was completed, the reaction mixture was stirred for 15 min at 0C, 45.36 mL (38.0 g, 0.127 mol, 1 equiv.) of2-octyl-1-dodecanol was added. The reaction mixture was stirred for 12 h at ambient temperature, concen- trated in a vacuum, the resultant suspension was diluted with 100 mL of petroleum ether, and filtered. The filtrate was passed through a thin layer of silica gel, washed with petroleum ether, and concentrated in a vacuum to give 43.61 g (95%) of viscous oil.1H NMR (400 MHz, CDCl3, delta, ppm): 3.47 (d, J =4.7 Hz, 2H), 1.66-1.54 (m, 1H), 1.45-1.17 (m, 32H),0.91 (t, J = 6.7 Hz, 6H).13C NMR (101 MHz, CDCl3, delta, ppm): 39.7, 39.5,32.5, 31.9, 29.8, 29.6, 29.6, 29.5, 29.3, 29.3, 26.5,22.6, 14.1.

With the rapid development of chemical substances, we look forward to future research findings about 5333-42-6.

Reference:
Article; Keshtov; Osipov; Topchiy; Zotova; Konstantinov; Krayushkin; Kuklin; Khokhlov; Doklady Chemistry; vol. 463; 2; (2015); p. 215 – 220; Dokl. Akad. Nauk; vol. 463; 6; (2015); p. 669 – 674,6;,
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Reference of 5333-42-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5333-42-6, name is 2-octyldodecan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

To a 250?mL two necked round bottom flask equipped with a stir bar, 2-octyl-1-dodecanol (20.0?g, 67.11?mmol), triphenylphosphine (21.10.g, 80.5?mmol), and imidazole (5.47?g, 80.5?mmol) in 100?mL of dichloromethane (DCM) was added at 0?C. Inert atmosphere was maintained. The solution was stirred for 15-20?min. Iodine (20.37?g, 80.5?mmol) was added to the solution with continuous stirring at 0?C. The reaction mixture was allowed to warm to room temperature over 2?h before 10?mL of sat. Na2SO3 (aq) was added. For work up firstly the organics were concentrated by evaporation, and the mixture was taken up in 200?mL of hexane washed three times with water and brine solution. The resulting mixture passed through a 3-4?cm silica gel plug, and dried over Na2SO4. The organics were concentrated by evaporation and dried under vacuum to give light yellow color oil (22.7?g, 93% yield). 1H?NMR (CDCl3, 200?MHz) deltappm: 3.01 (2H, S), 1.53 (1H, t), 1.48-1.45 (32H, s), 0.89 (t, 6H). 13C NMR (CDCl3, 200?MHz) deltappm: 13.2 (1C), 14.1(2C), 26.2 (2C), 27.7 (2C), 29.6 (4C), 29.3 (2C), 29.9 (3C), 31.9 (2C), 35.9 (1C), 39.2 (1C) Anal. Calcd for C20H41I (CHNS): C, 58.81; H, 10.12. Found: C, 58.70; H, 9.97 MALDI-TOF MS for (Calcd m/z?=?408.23) Found?=?408.97.

According to the analysis of related databases, 5333-42-6, the application of this compound in the production field has become more and more popular.

Reference:
Article; Mahale, Rajashree Y.; Dharmapurikar, Satej S.; Chini, Mrinmoy Kumar; Chemical Physics Letters; vol. 696; (2018); p. 48 – 54;,
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Application of 5333-42-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 5333-42-6, name is 2-octyldodecan-1-ol, molecular formula is C20H42O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

Example 6 Preparation of 2-octyldodecyl pentanoate To a 3-neck 1000 ml round-bottomed flask was added 2-octyl-1-dodecanol (140.0 g, 468.92 mmol, 1.0 equiv.), n-pentanoic acid (71.838 g, 703.40 mmol, 1.50 equiv.), toluene (175 ml) and p-toluenesulfonic acid monohydrate (0.8920 g, 4.689 mmol, 0.010 equiv.) at room temperature. The resulting mixture was heated at reflux with stirring in an oil bath at 134 C. under a nitrogen atmosphere for 12 hours. The water produced in the reaction was collected in a Dean-Stark trap. The cooled mixture was diluted with hexanes, washed with dilute aqueous 10% Na2CO3 solution, water, brine, dried (MgSO4), filtered, and concentrated in vacuo to afford a crude product. Excess solvent was further removed by heating the crude product with stirring in an oil bath under high vacuum for 3 hours to afford a light yellow liquid (178.0 g, 99%).

According to the analysis of related databases, 5333-42-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; ExxonMobil Research and Engineering Company; Ng, Man Kit; Oumar-Mahamat, Halou; Cheng, Hong; Blain, David A.; Cooper, Kathleen K.; Carey, James T.; Douglass, Michael R.; Kanga, Percy R.; Patil, Abhimanyu O.; Bodige, Satish; Lewis, Kyle G.; Hagemeister, Mark P.; (40 pag.)US2017/183595; (2017); A1;,
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Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5333-42-6, name is 2-octyldodecan-1-ol. This compound has unique chemical properties. The synthetic route is as follows. Formula: C20H42O

Into a 250 ml glass reactor fitted with an Argon purge was placed the nonanoic acid (20.5 grams, 0.2 moles), 2-octyl-1-dodecanol (29.9 grams, 0.1 moles) and p-toluene sulfonic acid monohydrate (19 grams, 0.1 moles). The mixture above was purged with Argon at room temperature for one hour. The mixture was then heated to 100 C. under Argon purge for 18 hours. The mixture was then cooled to room temperature. The residue was then dissolved into 100 ml with ethyl acetate and placed into a separatory funnel. The ethyl acetate solution was extracted once with 100 ml of distilled water. The ethyl acetate layer was washed with 250 ml 10 wt % NaHCO3 aqueous solution followed by 250 ml saturated NaCl aqueous solution. The ethyl acetate solution was dried over MgSO4 and then filtered. The ethyl acetate was removed on the rotary evaporator from the solution. The residue from the rotary evaporator was placed on a Kugelrohr vacuum distillation apparatus where the ester was distilled. 1H NMR (CDCl3): delta4.01 (d, 2H, O-CH2-), 2.31 (d, 2H, O=C-CH2-), 1.63-1.33 (m, 45H, -CH2-), 0.88 (t, 9H, CH3). IR (cm-1): 2955, 2954, 2854, 1738, 1466, 1378, 1251, 1251, 1165, 1107, 722.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 5333-42-6, 2-octyldodecan-1-ol.

Reference:
Patent; ExxonMobil Chemical Patents Inc.; Patil, Abhimanyu O.; Lewis, Kyle G.; Bodige, Satish; Zushma, Stephen; US2019/62663; (2019); A1;,
Alcohol – Wikipedia,
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Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 5333-42-6, name is 2-octyldodecan-1-ol. A new synthetic method of this compound is introduced below., category: alcohols-buliding-blocks

2-octyldecanol (2-Octyldecanol) (4.3 g, 14.5 mmol)Anhydrous DMFIt was dissolved in0 In NaH (60% dispersion inparaffin) (0.58 g, 14.5 mmol) to It was added. After stirring 1 hour the reaction solution at 0 With 5,6-difluoro-benzo [c] [1,2,5] – thiadiazole was added (1 g, 5.8 mmol). Then, and after stirring at room temperature for 12 hours to terminate the reaction was added to a saturated NH4Cl solution and extracted with 100 mL of diethyl ether.The extract solution after silica gel column chromatography was concentrated by vacuum distillation (DCM: Hexanes (1: 3)) to give the compound through a 1 (4.0 g, 95% yield).

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 5333-42-6, 2-octyldodecan-1-ol.

Reference:
Patent; Korea Research Institute of Chemical Technology; Lee, Jong Chul; Mun, Sang Jin; Sin, Won Suk; Lee, Sang Gyu; Song, Chang Uhn; Soh, Won Wook; Woo, Han Young; (18 pag.)KR2016/31958; (2016); A;,
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