Category: 473-81-4

On June 14, 2022, Moreira, Thamyres F. M.; Andrade, Adalgisa R.; Boniface Kokoh, K.; Morais, Claudia; Napporn, Teko W.; Olivi, Paulo published an article.COA of Formula: C3H6O4 The title of the article was An FTIR Study of the Electrooxidation of C2 and C3 Alcohols on Carbon-Supported PdxRhy in Alkaline Medium. And the article contained the following:

We have investigated the promoting effect of Rh addition to Pd-based materials in the electrooxidation of ethanol and glycerol. Physicochem. characterizations (XRD, EDX, TEM, and XPS) of the PdxRhy/C materials, prepared by bromide anion exchange (BAE), showed that the exptl. bimetallic compositions were close to the targeted ones. PdxRhy/C particle sizes ranged from 2.2 to 3.8 nm. The ethanol oxidation reaction (EOR) on the PdxRhy/C catalysts yielded four times larger carbonate (CO32-) amount As for the glycerol oxidation reaction (GOR), the onset potential on the Pd50Rh50/C catalyst occurred at lower potentials. Chromatog. anal. combined with in situ Fourier transform IR (FTIR) spectroscopy showed that GOR on the Pd50Rh50/C catalyst selectively and quant. produced glycerate and tartronate. The outstanding ability of the Pd50Rh50/C catalyst toward EOR and GOR was correlated to the electronic effect expressed by a neg. potential shift (200 mV) and the 47% alloying degree in the Pd50Rh50/C structure. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).COA of Formula: C3H6O4

The Article related to electrooxidation alc carbon palladium rhodium alk medium, Electrochemical, Radiational, and Thermal Energy Technology: Energy-Conversion Devices and Their Components and other aspects.COA of Formula: C3H6O4

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On September 30, 2022, Sidiq, Alif Lombardoaji; Floweri, Octia; Karunawan, Jotti; Abdillah, Oktaviardi Bityasmawan; Santosa, Sigit Puji; Iskandar, Ferry published an article.Computed Properties of 473-81-4 The title of the article was NCM cathode active materials reproduced from end-of-life Li-ion batteries using a simple and green hydrometallurgical recycling process. And the article contained the following:

LiNi1/3Co1/3Mn1/3O2 (NCM 111) cathode material was reproduced from end-of-life lithium-ion batteries (LIBs) via a green hydrometallurgical process including environmentally friendly DL-malic acid leaching, oxalate co-precipitation, and heat treatment. The leaching reached 95% efficiency by using glucose as reducing agent. X-ray fluorescence anal. revealed effective oxalate co-precipitation of metal ions in the form of MC2O4•2H2O (M = Ni, Co, Mn) with Ni, Co, and Mn ratio was approx. 1:1:1. Heat treatment on the mixture of precipitateand lithium salt at 900°C successfully reproduced NCM 111 cathode as confirmed via x-ray diffraction characterization. This sample also demonstrated comparable electrochem. properties with the fresh NCM cathode powder, with an initial specific discharge capacity of 158 mAh/g (0.2 C) and high rate capabilities. After 100 cycles of charge-discharge measurement at 0.2 C, this sample also revealed stable cycling ability with capacity retention of 93%, ensuring the good features of the reproduced cathode. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Computed Properties of 473-81-4

The Article related to lithium ion battery ncm cathode green hydrometallurgical recycling process, Electrochemical, Radiational, and Thermal Energy Technology: Energy-Conversion Devices and Their Components and other aspects.Computed Properties of 473-81-4

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Naik, Keerti M.; Hashisake, Kanaru; Hamada, Takuya; Higuchi, Eiji; Inoue, Hiroshi published an article in 2022, the title of the article was Intermetallic PdZn nanoparticles loaded on deficient TiO2 nanosheets as a support: a bifunctional electrocatalyst for oxygen reduction in PEMFCs and the glycerol oxidation reactions.Name: 2,3-Dihydroxypropanoic acid And the article contains the following content:

Exploring simple and flexible methods to synthesize an oxygen reduction reaction (ORR) catalyst with high catalytic activity is of great significance for the large-scale application of fuel cells. Here we developed an intermetallic PdZn on a TiO2-x NS support catalyst by a simple strategy for large-scale production through an impregnation process involving low temperature annealing. This electrocatalyst prepared by a simple and single step exhibited better ORR activities in both acidic and alk. solutions at room temperature with a higher value of electrochem. active surface area (ECSA). The repeated square-wave potential cycling test at 80°C over 10 000 cycles confirmed the durability of the catalyst. The fuel cell using the PdZn/TiO2-x NS catalyst showed a high power d. of 855 mW cm-2, which exceeds that of the PdZn supported carbon catalyst. Also, the proposed catalyst showed excellent stability over more than 100 h in proton-exchange membrane fuel cell (PEMFC) performance. Thus, the proposed TiO2-x NSs will be an alternative to a carbon support in future PEMFC technol. Furthermore, PdZn/TiO2-x NSs also showed higher activity and stability for the glycerol oxidation reaction (GOR) and higher selectivity for glycerate production than PdZn/C. Hence, the PdZn/TiO2-x NS electrocatalyst opens up new avenues towards energy conversion devices such as DAFCs and metal-air batteries. This new study provides an opportunity for further research to rationally design more carbon free supported nanostructured intermetallics by using different transition metals for efficient electrochem. energy storage devices. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Name: 2,3-Dihydroxypropanoic acid

The Article related to palladium zinc nanoparticle titania catalyst support pemfc glycerol oxidation, Electrochemical, Radiational, and Thermal Energy Technology: Energy-Conversion Devices and Their Components and other aspects.Name: 2,3-Dihydroxypropanoic acid

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On October 15, 2022, Chen, Xiong; Tang, Weinan; Cai, Lin; Zhu, Yuchen; Peng, Shaobo; Li, Xiaofei; Hu, Xiaoying; Qiao, Liang; Liu, Shujie published an article.Quality Control of 2,3-Dihydroxypropanoic acid The title of the article was Superdispersed NiCo2S4 nanoparticles anchored on reduced graphene oxide for efficient hydrogen evolution reaction in acidic and alkaline media. And the article contained the following:

Reasonable design and preparation of the earth abundant and efficient electrocatalysts for hydrogen production from the electrolysis of water is an effective solution to solve the growing global energy and environmental crisis. Herein, in order to increase the number of the active sites and fasten the charge transfer of NiCo2S4, a facile two-step solvothermal method is used to prepare superdispersed NiCo2S4 nanoparticles anchored on reduced graphene oxide (NCS/rGO) as low-cost and high-efficient electrocatalyst for hydrogen evolution reaction (HER). By modulating the amount of rGO, the as-prepared NCS/rGO composite shows high sp. surface area of 114.4 m2 g-1 and small particle size of 50-60 nm, which exhibits excellent HER activity with a lower overpotential of 115 mV at 10 mA cm-2 and a smaller charge transfer resistance of 12 Ω in acidic solution Addnl., in the case of alk. solution, the as-prepared NCS/rGO composite also exhibits a low overpotential of 241 mV and a small Tafel slope of 110 mV dec-1. The significantly improved HER performance of NCS/rGO composite can be ascribed to the constructed heterogeneous interface between NiCo2S4 nanoparticles and rGO, which can inhibit the aggregation of NiCo2S4 nanoparticles and enhance the intrinsic elec. conductivity In light of the excellent HER electrocatalytic performance, the inexpensive NCS/rGO composite might be regarded as a promising alternative in HER and other energy conversion and storage applications. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Quality Control of 2,3-Dihydroxypropanoic acid

The Article related to nickel cobalt sulfide reduced graphene oxide electrocatalyst hydrogen evolution, Electrochemical, Radiational, and Thermal Energy Technology: Energy-Conversion Devices and Their Components and other aspects.Quality Control of 2,3-Dihydroxypropanoic acid

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Zhang, Ziyan; Wu, Xiaojin; Zhou, Meng; Qi, Jiaqian; Zhang, Rui; Li, Xueqian; Wang, Chang; Ruan, Changgeng; Han, Yue published an article in 2022, the title of the article was Plasma metabolomics identifies the dysregulated metabolic profile of primary immune thrombocytopenia (ITP) based on GC-MS.Computed Properties of 473-81-4 And the article contains the following content:

ITP is a common autoimmune bleeding disorder with elusive pathogenesis. Author study was implemented to profile the plasma metabolic alterations of patients diagnosed with ITP, aiming at exploring the potential novel biomarkers and partial mechanism of ITP. The metabolomic anal. of plasma samples was conducted using GC-MS on 98 ITP patients and 30 healthy controls (HCs). Age and gender matched samples were selected to enter the training set or test set resp. OPLS-DA, t-test with FDR correction and ROC analyses were employed to screen out and evaluate the differential metabolites. Possible pathways were enriched based on metabolomics pathway anal. (MetPA). A total of 85 metabolites were investigated in author’s study and 17 differential metabolites with diagnostic potential were identified between ITP patients and HCs. MetPA showed that the metabolic disorders of ITP patients were mainly related to phenylalanine, tyrosine and tryptophan biosynthesis, phenylalanine metabolism and glyoxylate and dicarboxylate metabolism Addnl., author discriminated 6 differential metabolites and 5 enriched pathways in predicting the resistance to glucocorticoids in chronic ITP patients. The distinct metabolites discovered in author’s study could become novel biomarkers for the auxiliary diagnosis and prognosis prediction of ITP. Besides, the dysregulated pathways might contribute to the development of ITP. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Computed Properties of 473-81-4

The Article related to metabolome immune thrombocytopenia gcms, opls -da, gas chromatography tandem mass spectrometry, metabolomics, metabolomics pathway analysis, primary immune thrombocytopenia and other aspects.Computed Properties of 473-81-4

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On July 1, 2022, Patel, Monika; Fatnani, Dhara; Parida, Asish Kumar published an article.COA of Formula: C3H6O4 The title of the article was Potassium deficiency stress tolerance in peanut (Arachis hypogaea) through ion homeostasis, activation of antioxidant defense, and metabolic dynamics: Alleviatory role of silicon supplementation. And the article contained the following:

Potassium (K) scarcity of arable land is one of the important factors that hamper the growth of the plants and reduce yield worldwide. In the current study, we examine the physiol., biochem., and metabolome response of Arachis hypogaea (GG7 genotype: fast-growing, tall, early maturing, and high yielding) under low K either solitary or in combination with Si to elucidate the ameliorative role of Si. The reduced fresh and dry biomass of peanut and photosynthetic pigments content was significantly alleviated by Si. Si application did not affect the leaf and stem K+, although it enhanced root K+ in K-limitation, which is probably due to up-regulated expression of genes responsible for K uptake. Si improves the potassium use efficiency in K-limitation as compared to control. K-deficiency increased MDA, O·-2, and H2O2 levels in leaf and root of peanut. Si improved/maintained the activity of antioxidative enzymes, which significantly lowered the ROS accumulation in K-limitation. The AsA/DHA and GSH/GSSG ratio was approx. unaffected in both leaf and root, suggesting the maintained cellular redox potential in K-starved peanut. Si promotes accumulation of sugars and sugar alcs., phytohormones indicating their probable involvement in signal transduction, osmotic regulation, and improvement of stress tolerance. Down-regulation of aspartic acid and glutamic acid while up-regulation of lysine, histidine, and arginine could maintain charge balance in K-deprived peanut. The significant accumulation of polyphenols under K limitation supplemented with Si suggests the role of polyphenols for ROS scavenging. Our results demonstrated that Si as a beneficial element can mitigate K-nutrient toxicity and improve KUE of peanut under K-limitation conditions. Moreover, our results demonstrate that Si application can improve crop yield, quality, and nutrient use efficiency under nutrient limitation conditions. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).COA of Formula: C3H6O4

The Article related to arachis potassium deficiency stress tolerance antioxidant silicon ion homeostasis, arachis hypogaea, aspartic acid, metabolomics, myo-inositol, phytohormones, potassium, silicon and other aspects.COA of Formula: C3H6O4

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On October 1, 2022, Qie, Mengjie; Li, Tiwen; Liu, Charles C.; Zhao, Yan published an article.Electric Literature of 473-81-4 The title of the article was Direct analysis in real time high-resolution mass spectrometry for authenticity assessment of lamb. And the article contained the following:

In comparison to more traditional methods of determining food authenticity, such as gas chromatog. anal., the primary advantages of DART-HRMS include its high speed and throughput of anal. This study used a non-targeted metabolomics method based on real-time high-resolution mass spectrometry combined with chemometric anal. to distinguish lamb samples from four regions. Orthogonal least squares-discriminant anal. revealed a distinct difference between these four lamb regions. The potential markers were chosen based on the variables importance in projection values, variance, and fold change. A total of 79 markers were identified using the matching chem. database. These markers differed significantly between lambs in four regions according to heatmap anal. The linear discriminatory anal. model had an initial classification rate of 100.0% and a cross-validation accuracy of 82.50% on the identified markers. The research demonstrates that DART-HRMS can perform a rapid authentication evaluation of lamb samples. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Electric Literature of 473-81-4

The Article related to real time high resolution mass spectrometry lamb authenticity assessment, dart–tofms, food authentication, lamb, metabolomic fingerprinting, multivariate analysis, untargeted method and other aspects.Electric Literature of 473-81-4

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On August 31, 2022, Ma, Xiaoyao; Bai, Yongping; Liu, Kaixin; Han, Yiman; Zhang, Jinling; Liu, Yuteng; Hou, Xiaotao; Hao, Erwei; Hou, Yuanyuan; Bai, Gang published an article.HPLC of Formula: 473-81-4 The title of the article was Ursolic acid inhibits the cholesterol biosynthesis and alleviates high fat diet-induced hypercholesterolemia via irreversible inhibition of HMGCS1 in vivo. And the article contained the following:

In hypercholesteremia, the concentrations of total cholesterol (TC) and low-d. lipoprotein cholesterol (LDL-C) are enhanced in serum, which is strongly associated with an increased risk of developing atherosclerosis. Ursolic acid (UA), a pentacyclic terpenoid carboxylic acid, was found to alleviate hypercholesterolemia and hypercholesterolemia-induced cardiovascular disease. However, the specific targets and mol. mechanisms related to the effects of UA in reducing cholesterol have not been elucidated. In this study, we aimed to illustrate the target of UA in the treatment of hypercholesterolemia and to reveal its underlying mol. mechanism. Nontargeted metabolomics was conducted to analyze the metabolites and related pathways that UA affected in vivo. The main lipid metabolism targets of UA were analyzed by target fishing and fluorescence colocalization in mouse liver. Mol. docking, in-gel fluorescence scan and thermal shift were assessed to further investigate the binding site of the UA metabolite with HMGCS1. C57BL/6 mice were fed a high-fat diet (HFD) for 12 wk to induce hypercholesteremia. Liver tissues were used to verify the cholesterol-lowering mol. mechanism of UA by targeted metabolomics, serum was used to detect biochem. indexes, and the entire aorta was used to analyze the formation of atherosclerotic lesions. Our results showed that hydroxy-3-methylglutaryl CoA synthetase 1 (HMGCS1) was the primary lipid metabolism target protein of UA. The UA metabolite epoxy-modified UA irreversibly bonds with the thiol of Cys-129 in HMGCS1, which inhibits the catalytic activity of HMGCS1 and reduces the generation of precursors in cholesterol biosynthesis in vivo. The contents of TC and LDL-C in serum and the formation of the atherosclerotic area in the entire aorta were markedly reduced with UA treatment in Diet-induced hypercholesteremia mice. UA inhibits the catalytic activity of HMGCS1, reduces the generation of downstream metabolites in the process of cholesterol biosynthesis and alleviates Diet-induced hypercholesteremia via irreversible binding with HMGCS1 in vivo. It is the first time to clarify the irreversible inhibition mechanism of UA against HMGCS1. This paper provides an increased understanding of UA, particularly regarding the mol. mechanism of the cholesterol-lowering effect, and demonstrates the potential of UA as a novel therapeutic for the treatment of hypercholesteremia. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).HPLC of Formula: 473-81-4

The Article related to ursolic acid anticholesteremic hmgcs1 cholesterol biosynthesis hypercholesterolemia, cholesterol biosynthesis, covalent binding, hmgcs1, hypercholesteremia, metabolite, ursolic acid and other aspects.HPLC of Formula: 473-81-4

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On February 28, 2022, Xu, Kailin; Zhang, Qiuya; Wang, Chuqiao; Xu, Jinmei; Bu, Yiming; Liang, Bin; Liu, Yushuai; Wang, Liping published an article.Application In Synthesis of 2,3-Dihydroxypropanoic acid The title of the article was 0D boron carbon nitride quantum dots decorated 2D Bi4O5I2 as 0D/2D efficient visible-light-driven photocatalysts for tetracyclines photodegradation. And the article contained the following:

A series of 0D boron carbon nitride quantum dots (BCNQDs) modified 2D Bi4O5I2(0D/2D Bi4O5I2/BCNQDs) composites were synthesized and applied to photodegradation of tetracyclines (TCs), including tetracycline (TC) and oxytetracycline (OTC). The Bi4O5I2/BCNQDs (1) (1 mL BCNQDs) composite exhibits the highest photocatalytic performance for TCs degradation The degradation rate constants of TC and OTC by the optimal sample were 4.95 and 2.17 times that of Bi4O5I2, resp. This can be attributed to the fact that the narrow bandgap Bi4O5I2is the electron acceptor, and the oxygen-containing functional group with the neg. charge on BCNQDs can promote the formation of photoexcited holes, which makes the effective separation of photoexcited carriers easier. Furthermore, the active substance (h+ and ·O-2) is the major active substance for TCs photodegradation On this basis, the possible photocatalytic reaction mechanism of Bi4O5I2/BCNQDs (1) composite is proposed. This study provides a new idea for 0D/2D interface engineering of BCNQDs heterojunction. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Application In Synthesis of 2,3-Dihydroxypropanoic acid

The Article related to boron carbon nitride quantum dot bismuth oxyiodide photocatalyst photodegradation, 0d/2d heterojunction, bi(4)o(5)i(2), boron carbon nitride quantum dots, photocatalysis, tetracyclines and other aspects.Application In Synthesis of 2,3-Dihydroxypropanoic acid

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On January 20, 2022, Lee, Hwanhui; To, Ngoc Bao; Kim, Myeongsun; Nguyen, Yen Thi-Kim; Cho, Somi Kim; Choi, Hyung-Kyoon published an article.Application In Synthesis of 2,3-Dihydroxypropanoic acid The title of the article was Metabolic and lipidomic characterization of radioresistant MDA-MB-231 human breast cancer cells to investigate potential therapeutic targets. And the article contained the following:

To provide preliminary insights into metabolic and lipidomic characteristics in radioresistant triple-neg. breast cancer (TNBC) cells and suggest potential therapeutic targets, we performed a comprehensive metabolic and lipidomic profiling of radioresistant MDA-MB-231 (MDA-MB-231/RR) TNBC cells and their parental cells using gas chromatog.-mass spectrometry and nano electrospray ionization-mass spectrometry, followed by multivariate statistical anal. Buthionine sulfoximine (BSO) and radiation were co-treated to radioresistant TNBC cells. The level of glutathione (GSH) was significantly increased, and the levels of GSH synthesis-related metabolites, such as cysteine, glycine, and glutamine were also increased in MDA-MB-231/RR cells. In contrast, the level of lactic acid was significantly reduced. In addition, reactive oxygen species (ROS) level was decreased in MDA-MB-231/RR cells. In the lipidomic profiles of MDA-MB-231/RR cells, the levels of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) were significantly increased, whereas those of most of the phosphatidylinositol species were significantly decreased. BSO sensitized MDA-MB-231/RR cells to radiotherapy, which resulted in decreased GSH level and increased ROS level and apoptosis. Radioresistant TNBC cells showed distinct metabolic and lipidomic characteristics compared to their parental cells. We suggested activated GSH, PC, and PE biosynthesis pathways as potential targets for treating radioresistant TNBC cells. Particularly, enhanced radiosensitivity was achieved by inhibition of GSH biosynthesis in MDA-MB-231/RR cells. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Application In Synthesis of 2,3-Dihydroxypropanoic acid

The Article related to radioresistant mda mb231 breast cancer cell metabolic lipidomic characterization, lipidomic profiling, mda-mb-231, metabolic profiling, radioresistance, triple-negative breast cancer and other aspects.Application In Synthesis of 2,3-Dihydroxypropanoic acid

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