Category: 473-81-4

Lopez-Ortiz, Carlos; Edwards, Mary; Natarajan, Purushothaman; Pacheco-Valenciana, Armando; Nimmakayala, Padma; Adjeroh, Donald A.; Sirbu, Cristian; Reddy, Umesh K. published an article in 2022, the title of the article was Peppers in Diet: Genome-Wide Transcriptome and Metabolome Changes in Drosophila melanogaster.Quality Control of 2,3-Dihydroxypropanoic acid And the article contains the following content:

The habanero pepper (Capsicum chinense) is an increasingly important spice and vegetable crop worldwide because of its high capsaicin content and pungent flavor. Diets supplemented with the phytochems. found in habanero peppers might cause shifts in an organism’s metabolism and gene expression. Thus, understanding how these interactions occur can reveal the potential health effects associated with such changes. We performed transcriptomic and metabolomic analyses of Drosophila melanogaster adult flies reared on a habanero pepper diet. We found 539 genes/59 metabolites that were differentially expressed/accumulated in flies fed a pepper vs. control diet. Transcriptome results indicated that olfactory sensitivity and behavioral responses to the pepper diet were mediated by olfactory and nutrient-related genes including gustatory receptors (Gr63a, Gr66a, and Gr89a), odorant receptors (Or23a, Or59a, Or82a, and Orco), and odorant-binding proteins (Obp28a, Obp83a, Obp83b, Obp93a, and Obp99a). Metabolome anal. revealed that campesterol, sitosterol, and sucrose were highly upregulated and azelaic acid, Et phosphoric acid, and citric acid were the major metabolites downregulated in response to the habanero pepper diet. Further investigation by integration anal. between transcriptome and metabolome data at gene pathway levels revealed six unique enriched pathways, including phenylalanine metabolism; insect hormone biosynthesis; pyrimidine metabolism; glyoxylate, and dicarboxylate metabolism; glycine, serine, threonine metabolism; and glycerolipid metabolism In view of the transcriptome and metabolome findings, our comprehensive anal. of the response to a pepper diet in Drosophila have implications for exploring the mol. mechanism of pepper consumption. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Quality Control of 2,3-Dihydroxypropanoic acid

The Article related to transcriptome metabolome metabolite phytochem drosophila diet capsaicin capsicum, drosophila, diet, habanero pepper, metabolome, transcriptome, Nonmammalian Biochemistry: Classical Genetics and Phylogeny and other aspects.Quality Control of 2,3-Dihydroxypropanoic acid

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Deidda, Martino; Noto, Antonio; Cadeddu Dessalvi, Christian; Andreini, Daniele; Andreotti, Felicita; Ferrannini, Eleuterio; Latini, Roberto; Maggioni, Aldo P.; Magnoni, Marco; Mercuro, Giuseppe; on behalf of the CAPIRE Investigators published an article in 2022, the title of the article was Why Do High-Risk Patients Develop or Not Develop Coronary Artery Disease? Metabolic Insights from the CAPIRE Study.Computed Properties of 473-81-4 And the article contains the following content:

Traditional cardiovascular (CV) risk factors (RFs) and coronary artery disease (CAD) do not always show a direct correlation. We investigated the metabolic differences in a cohort of patients with a high CV risk profile who developed, or did not develop, among those enrolled in the Coronary Atherosclerosis in Outlier Subjects: Protective and Novel Individual Risk Factors Evaluation (CAPIRE) study. We studied 112 subjects with a high CV risk profile, subdividing them according to the presence (CAD/High-RFs) or absence of CAD (No-CAD/High-RFs), assessed by computed tomog. angiog. The metabolic differences between the two groups were identified by gas chromatog.-mass spectrometry. Characteristic patterns and specific metabolites emerged for each of the two phenotypic groups: high concentrations of pyruvic acid, pipecolic acid, p-cresol, 3-aminoisobutyric acid, isoleucine, glyceric acid, lactic acid, sucrose, phosphoric acid, trimethylamine-N-oxide, 3-hydroxy-3-methylglutaric acid, erythritol, 3-hydroxybutyric acid, glucose, leucine, and glutamic acid; and low concentrations of cholesterol, hypoxanthine, glycerol-3-P, and cysteine in the CAD/High-RFs group vs the No-CAD/High-RFs group. Our results show the existence of different metabolic profiles between patients who develop CAD and those who do not, despite comparable high CV risk profiles. A specific cluster of metabolites, rather than a single marker, appears to be able to identify novel predisposing or protective mechanisms towards CAD beyond classic CVRFs. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Computed Properties of 473-81-4

The Article related to pyruvic pipecolic acid isoleucine p cresol coronary artery disease, atherosclerosis, cardiovascular risk factors, coronary artery diseases, metabolomics, Mammalian Pathological Biochemistry: Cardiovascular Diseases and other aspects.Computed Properties of 473-81-4

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On July 19, 2022, Feng, Haichao; Lv, Yu; Krell, Tino; Fu, Ruixin; Liu, Yunpeng; Xu, Zhihui; Du, Wenbin; Shen, Qirong; Zhang, Nan; Zhang, Ruifu published an article.Computed Properties of 473-81-4 The title of the article was Signal binding at both modules of its dCache domain enables the McpA chemoreceptor of Bacillus velezensis to sense different ligands. And the article contained the following:

Bacteria have evolved multiple signal transduction systems that permit an adaptation to changing environmental conditions. Chemoreceptor-based signaling cascades are very abundant in bacteria and are among the most complex signaling systems. Currently, our knowledge on the mol. features that determine signal recognition at chemoreceptors is limited. Chemoreceptor McpA of Bacillus velezensis SQR9 has been shown to mediate chemotaxis to a broad range of different ligands. Here we show that its ligand binding domain binds directly 13 chemoattractants. We provide support that organic acids and amino acids bind to the membrane-distal and membrane-proximal module of the dCache domain, resp., whereas binding of sugars/sugar alcs. occurred at both modules. Structural biol. studies combined with site-directed mutagenesis experiments have permitted to identify 10 amino acid residues that play key roles in the recognition of multiple ligands. Residues in membrane-distal and membrane-proximal regions were central for sensing organic acids and amimo acids, resp., whereas all residues participated in sugars/sugar alc. sensing. Most characterized chemoreceptors possess a narrow and well-defined ligand spectrum. We propose here a sensing mechanism involving both dCache modules that allows the integration of very diverse signals by a single chemoreceptor. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Computed Properties of 473-81-4

The Article related to bacillus mcpa chemoreceptor dcache domain signal ligand binding chemoattractant, chemoreceptor, chemotaxis, dcache sensor domain, ligand recognition, signal transduction, Microbial, Algal, and Fungal Biochemistry: Classical Genetics and other aspects.Computed Properties of 473-81-4

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Beyoglu, Diren; Park, Eun-Jung; Quinones-Lombrana, Adolfo; Dave, Asim; Parande, Falguni; Pezzuto, John M.; Idle, Jeffrey R. published an article in 2022, the title of the article was Addition of grapes to both a standard and a high-fat Western pattern diet modifies hepatic and urinary metabolite profiles in the mouse.Reference of 2,3-Dihydroxypropanoic acid And the article contains the following content:

The benefits of fruit and vegetable dietary consumption are largely defined in epidemiol. terms. Relatively little is known about the discrete effects on metabolic pathways elicited by individual dietary fruits and vegetables. To address this, grape powder was added to both a standard and a high-fat Western pattern diet given to 10-wk-old female C57BL/6J mice for a period of 91 days, whereupon 24 h urines were collected and the mice euthanized after a 12 h fast for the collection of liver tissue. Alterations in hepatic and urinary metabolite patterns were determined by gas chromatog.-mass spectrometry-based metabolomics. Urinary excretion of the gut microbiota metabolites 4-hydroxyphenylacetic acid, 5-hydroxyindole, glyceric acid, gluconic acid and myo-inositol was attenuated when grape was added to the standard diet but the gut microbiota metabolites gluconic acid, scyllo-inositol, mannitol, xylitol, 5-hydroxyindole and 2-deoxyribonic acid were increased in urine when grape was added to the high-fat diet. Increased hepatic ascorbic acid and 5-oxoproline levels indicated the anti-oxidant effect of grape powder on the liver. Pathway enrichment anal. demonstrated that for both standard and high-fat diets, grape addition significantly upregulated the malate-aspartate shuttle indicating enhanced hepatic utilization of glucose via cytosolic glycolysis for mitochondrial ATP production It is concluded that a grape diet reprogrammes gut microbiota metabolism, attenuates the hepatic oxidative stress of a high-fat diet and increases the efficiency of glucose utilization by the liver for energy production The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Reference of 2,3-Dihydroxypropanoic acid

The Article related to glyceric acid myoinositol liver urine grape high fat diet, Food and Feed Chemistry: Fruits, Vegetables, Legumes, and Nuts and other aspects.Reference of 2,3-Dihydroxypropanoic acid

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On June 30, 2022, Indrati, Niken; Sumpavapol, Punnanee; Samakradhamrongthai, Rajnibhas Sukeaw; Phonsatta, Natthaporn; Poungsombat, Patcha; Khoomrung, Sakda; Panya, Atikorn published an article.Application In Synthesis of 2,3-Dihydroxypropanoic acid The title of the article was Volatile and non-volatile compound profiles of commercial sweet pickled mango and its correlation with consumer preference. And the article contained the following:

Summary : Sweet pickled mango named Ma-Muang Bao Chae-Im is a traditional preserved mango from Hat Yai, Thailand. This study investigated (I) volatile and non-volatile compound profiles of com. Ma-Muang Bao Chae-Im and (II) their relationship to consumer preference. Untargeted metabolomics profiling was performed by gas chromatog.-mass quadrupole-time of flight anal. There were 117 volatile and 44 non-volatile compounds annotated in six com. brands of Ma-Muang Bao Chae-Im. Furthermore, 46 volatile and 19 non-volatile compounds discriminant markers were found by Partial least square discriminant anal. Among those markers, sorbic and benzoic acid were observed in several brands; moreover, the combination of both compounds altered the volatile profile, especially the ester group. Partial least square regression revealed that overall consumer liking is correlated to 1-heptanol; 1-octanol; acetoin; acetic acid, 2-phenylethyl ester; D-manitol; terpenes and terpenoids, while firmness to sucrose and L-(-)-sorbofuranose. On the other hand, most ester compounds were not related to consumer preference. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Application In Synthesis of 2,3-Dihydroxypropanoic acid

The Article related to sweet pickled mango 1heptanol 1octanol acetoin acetic acid, Food and Feed Chemistry: Fruits, Vegetables, Legumes, and Nuts and other aspects.Application In Synthesis of 2,3-Dihydroxypropanoic acid

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On June 30, 2022, Sapara, Komal K.; Agarwal, Parinita; Gupta, Kapil; Agarwal, Pradeep K. published an article.Recommanded Product: 473-81-4 The title of the article was Expression of B. subtilis Phytase gene driven by fruit specific E8 promoter for enhanced minerals, metabolites and phytonutrient in cucumber fruit. And the article contained the following:

The fruit nutrigenomics is an interesting and important research area towards nutrition enhancement. The phytic acid is one of the major antinutrient compound, present in seeded fruits and crops. It hinders the absorption of iron (Fe), zinc (Zn), magnesium (Mg), potassium (K) and calcium (Ca), causing mineral deficiencies. In the present study, the BsPhy gene was overexpressed in the cucumber fruits using the tomato fruit specific E8 and constitutive CaMV 35S promoter. The E8 promoter imparted heterologous expression of GUS gene in cucumber fruits, furthermore, the fruit specific expression of E8 promoter with BsPhy gene was confirmed in transgenics (E8: BsPhy) using anti rabbit-phytase antibody. The physio-biochem. anal. of transgenics revealed, maximum phytase activity in E8: BsPhy cucumber fruits at 10 days after anthesis (DAA) compared to 35S: BsPhy and wild-type (WT) fruits. Consequently, E8: BsPhy fruits also showed increased amount of inorganic phosphorus (Pi), total phosphorus (P), minerals (Zn, Fe, Mg, K, Ca), total carotenoid and other macronutrients at 10 DAA compared to 35S: BsPhy fruits. The metabolite profiling of fruits (10 DAA) showed increased sugars, amino acids, sugar acids and polyols, in both E8: BsPhy and 35S: BsPhy transgenics suggesting higher phytate metabolism, compared to WT fruits. Interestingly, both the transgenic fruits showed higher fruit biomass and yield along with improved nutritional quality, which can be attributed to increased P and Zn contents in transgenic fruits, compared to WT fruits. Our findings reveal that the BsPhy gene enhances minerals and macronutrients in transgenic cucumber fruits making it nutritious and healthy. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Recommanded Product: 473-81-4

The Article related to bacillus subtilis mineral cucumber fruit metabolite phytonutrient, antinutrient, heterologous, metabolites, minerals, nutrigenomics, transgenic, Food and Feed Chemistry: Fruits, Vegetables, Legumes, and Nuts and other aspects.Recommanded Product: 473-81-4

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On October 1, 2022, Yang, Xiaozhe; Hu, Wenzhong; Xiu, Zhilong; Ji, Yaru; Guan, Yuge published an article.Recommanded Product: 2,3-Dihydroxypropanoic acid The title of the article was Interactions between Leu. mesenteroides and L. plantarum in Chinese northeast sauerkraut. And the article contained the following:

LAB are mostly used microorganisms for traditional fermented foods, e.g. Chinese northeast sauerkraut. However, the interactions between these strains are little known in mixed culture. This study aimed to explore the interaction between Leu. mesenteroides and L. plantarum based on metabolomics and transcriptomics during single- and mix-cultured fermentation of Chinese northeast sauerkraut. Metabolomics anal. revealed that the mixed culture showed different metabolite profiles in comparison with single culture. Higher levels of 4-vinylphenol (4.51%), 2,6-diaminopimelic acid (4.47%), Et dodecanoate (5.53%) were observed in mix-cultured samples than that with Leu. mesenteroides. In addition, the levels of 4-isopropylbenzoic acid (3.54%), 2,3-butanediol (7.23%), 1-octadecene (5.15%), Et dodecanoate (5.53%) were higher than that with L. plantarum. The most influenced pathway was carbohydrate metabolism, which was mostly related to 116 genes considered as DEGs in C_30 vs. D_30 groups (CD), according to transcriptomics anal. Addnl., 69 genes were considered as significantly DEGs in C_30 vs. A_30 groups (CA) which were considerably mapped to amino acid metabolism These results provided integrated views into the adaptive responses of the two strains to mix-cultured fermentation, which was useful for the rational development of mixed cultures in sauerkraut industry. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Recommanded Product: 2,3-Dihydroxypropanoic acid

The Article related to sauerkraut leuconostoc mesenteroides lactobacillus plantarum interaction, Food and Feed Chemistry: Fruits, Vegetables, Legumes, and Nuts and other aspects.Recommanded Product: 2,3-Dihydroxypropanoic acid

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On August 31, 2022, Karakurt, Huseyin; Kartal, Ozlem Esen published an article.Formula: C3H6O4 The title of the article was Removal of Reactive Red 120 using immobilized TiO2 in the presence of UV light. And the article contained the following:

Removal of Reactive Red 120 (RR120) dye in aqueous solution was investigated using immobilized TiO2 in the presence of UV light. TiO2 was deposited onto microscope slides by heat attachment method. SEM analyses confirmed that all microscope slides were coated with TiO2 particles completely after single, two, three and four layers coating. The removal efficiency increased with repetitive coating up to three layers. The highest removal efficiency of 94% was obtained at pH 3 within 300 min of reaction time. Complete removal was observed with 5 and 10 mg dm-3 dye concentrations whereas removal efficiency decreased from 96 to 52% when initial RR120 concentration increased 15 mg dm-3 to 30 mg dm-3. The results of nonlinear optimization showed that the kinetics of removal of RR120 in the range of concentration studied described by L-H kinetic expression. The experiments conducted with radical scavengers indicated that hydroxyl radicals and photogenerated hole and electrons were main reactive species in photocatalytic removal of RR120. The photonic efficiency of immobilized system was lower than that of suspended system. Minor drop (6%) in the removal of RR120 with three layers coated slide after four consecutive cycles of 300 min indicated the reusability and stability of coated slides. A possible degradation mechanism for degradation of RR120 was proposed according to detected intermediate compounds Mineralization of RR120 was monitored by generation of NO3- and SO42- ions in solution during photocatalytic reaction. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Formula: C3H6O4

The Article related to titanium dioxide reactive red removal uv light, Waste Treatment and Disposal: Physical Treatment Of Aqueous Wastes and other aspects.Formula: C3H6O4

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On August 29, 2022, Fu, Qiang; Shofner, Meisha L.; Sinquefield, Scott A.; Nair, Sankar published an article.Application In Synthesis of 2,3-Dihydroxypropanoic acid The title of the article was Recovery and Enrichment of Organic Acids from Kraft Black Liquor by an Adsorption-Based Process. And the article contained the following:

Kraft black liquor (BL) is a complex multicomponent byproduct from wood pulping processes. After lignin, carbohydrate-derived carboxylic acids are the second most abundant class of organics in kraft BL and comprise a potential biomass-derived feedstock of more than 50 million tons/yr globally. These acids can be valorized in biofuels and biobased chems. production or further fractionated to produce specific high-value carboxylic acids from the mixture However, both of these routes require a viable process to sep. carboxylic acids from BL. In this work, an adsorption-based process was developed to address this challenging issue. The kraft BL stream was first pretreated to remove most of the lignin by membrane nanofiltration (NF) combined with lignin-selective adsorption. To sep. organic acids from this pretreated BL, organophilic/hydrophobic granulated activated carbon (GAC) was identified as a promising adsorbent with excellent organic/inorganic selectivity and adsorption capacity (>100 mg/g GAC). We present comprehensive adsorption measurements and anal. to characterize the adsorbent and develop a viable cyclic operation scheme for the adsorption process. The GAC adsorbents show robust separation performance over 20+ cycles. We have successfully obtained concentrated aqueous organic acid mixtures with ~95% purity from kraft BL. We propose a modified kraft process with energy-efficient BL dewatering by NF and organic acids recovery for valorization. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Application In Synthesis of 2,3-Dihydroxypropanoic acid

The Article related to enrichment organate kraft black liquor adsorption, Cellulose, Lignin, Paper, and Other Wood Products: Pulp and Liquors and other aspects.Application In Synthesis of 2,3-Dihydroxypropanoic acid

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On September 15, 2022, Lu, Yunhao; Yang, Linzi; An, Yunfeng; Liu, Dayu; Yang, Guohua; He, Qiang published an article.Electric Literature of 473-81-4 The title of the article was Salt tolerance and ester production mechanisms of Candida etchellsii in Chinese horse bean-chili-paste. And the article contained the following:

Candida etchellsii is a predominant strain in Chinese horse bean-chili-paste, a famous and traditional condiment with high salt content. In this study, physiol. properties, ester production capacity and gene expression of C. etchellsii under salt stress were investigated, and the results showed that the strain evoked miscellaneous regulations to resist high salt stress. Under salt stress, C. etchellsii would accumulate intracellular glycerol, Na+ and K+ to balance osmotic pressure. Interestingly, the strain showed much stronger capacity to yield Et hexanoate and hexyl acetate after 5% and 20% (w/v) NaCl treatment whether in esterification or alcoholysis system. Furthermore, transcriptome data indicated that the genes associated with carbohydrate metabolism and amino acid metabolism had significantly different expression, and their regulations were consistent with the results of physiol. anal. The results obtained in this study could contribute to understand the salt tolerance mechanism of C. etchellsii and provide a theor. support for its application in traditional food fermentation The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Electric Literature of 473-81-4

The Article related to chinese horse bean chili paste candida sodium chloride stress, Food and Feed Chemistry: Additives, Sweeteners, Flavorings, Condiments, and Confectionery and other aspects.Electric Literature of 473-81-4

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