Category: 4543-95-7

Cincinelli, Raffaella published the artcileIntramolecular N-acyliminium ion versus Friedel-Crafts cyclization onto 3-indoles: synthesis of the novel rings pyrrolizino[2,1-b]indole and homologues, Quality Control of 4543-95-7, the publication is Tetrahedron (2009), 65(17), 3465-3472, database is CAplus.

Acid treatment of indole-2-carboxylic acid secondary δ-,ε-, and ζ-oxoamides cyclize to the novel heterocyclic ring systems pyrrolizino[2,1-b]indole (I, n = 1), indolizino[2,1-b]indole (I, n = II), and 9a,11-diaza-indeno[1,2-a]azulene (I, n = 3) with varying substitution. Tertiary amides cyclize through a simple Friedel-Crafts ring closure, thus allowing the synthesis of tricyclic ring systems containing larger rings, e.g., II.

Tetrahedron published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, Quality Control of 4543-95-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Natarajan, P. N. published the artcileSynthesis and pharmacological evaluation of N-alkylamino butanol esters of 3,4,5-trimethoxybenzoic acid as potential hypotensive agents, HPLC of Formula: 4543-95-7, the publication is Canadian Journal of Pharmaceutical Sciences (1973), 8(2), 61-3, database is CAplus.

The title esters I (R = Me, Et, Pr, Me2CH, Bu) were prepared by condensing γ-butyrolactone with RNH2, reducing the resulting HO(CH2)3CONHR with LiAlH4, and esterifying the hydrochlorides of the amines formed with 3,4,5-(MeO)3C6H2COCl in C6H6 at ∼70° under N for 15-20 hr. Evaluation of I, for hypotensive activity in normotensive rats and for central nervous system activity in mice showed that I did not have any reserpine-like activity.

Canadian Journal of Pharmaceutical Sciences published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, HPLC of Formula: 4543-95-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hecht, Stephen S. published the artcileA study of chemical carcinogenesis. II. Synthesis of N-nitrosamino aldehydes, HPLC of Formula: 4543-95-7, the publication is Tetrahedron Letters (1976), 593-6, database is CAplus.

The alcs. RNHCHR1(CH2)3OH (I; R = Pr, Me, PhCH2, R1 = H) were prepared from Cl(CH2)4OH and the corresponding amine; I (R = Me, R1 = 3-pyridyl) was prepared by condensation of Et nicotinate with butyrolactone to give dihydro-3-(3-pyridoyl)-2-(3H)-furanone, which was successively hydrolyzed, decarboxylated, and treated with NaBH3CN and MeNH2. Nitrosation of I with NaNO2 gave RN(N:O)CHR1(CH2)3OH which was oxidized with dicyclohexylcarbodiimide in DMSO to give RN(N:O)CHR1(CH2)2CHO. The aldehydes were mixtures of Z- and E-isomers.

Tetrahedron Letters published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, HPLC of Formula: 4543-95-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Schade, W. published the artcilePolyfunctionalized nitrogen-containing surfactants. IV. Synthesis of hydroxy- and chlorine substituted alkylamines – structure dependence of the extraction of zinc ions from hydrochloric acid, HPLC of Formula: 4543-95-7, the publication is Journal fuer Praktische Chemie (Leipzig) (1983), 325(3), 364-74, database is CAplus.

RNHCH₂CH(OH)Me (R = C₁₀, C₁₂, C₁₄, C₁₆ n-alkyl); RNH(CH₂)₃OH (R = C₁₀, C₁₁, C₁₂, C₁₄, C₁₆, C₁₈ n-alkyl), R₂N(CH₂)₃OH (R = C₁₀, C₁₁, C₁₂, C₁₄, C₁₆ n-alkyl), RNH(CH₂)₄OH (R = C₆, C₈, C₁₀, C₁₂, C₁₄, C₁₆ n-alkyl), R¹R²NPr (R¹ = decyl, R² = H, Me, Pr, decyl; R¹ = dodecyl, R² = Pr, dodecyl), R¹NHBu (R¹ = C₁₀, C₁₂, C₁₄, C₁₆ n-alkyl), RNH(CH₂)_mCl.HCl (R = Bu, hexyl, octyl, decyl, dodecyl, n = 3, 4; R = decyl, dodecyl, n = 2), R¹R²NCH₂CH₂OH (R¹ = dodecyl, R² = H, dodecyl), [Me(CH₂)₁₁]₂N(CH₂)₄OH, Me(CH₂)₉NR(CH₂)₃OH (R = Me, Pr), and Me(PhCH₂)N⁺R(CH₂)₃OH Cl^– (R = octyl, dodecyl) were prepared by known procedures and tested for their extraction power for Zn²⁺. The extractability of Zn²⁺ increases secondary < tertiary < quaternary amine function, is independent of the length of the longest alkyl chain between 10 and 16 cations, and increases with a given substituent in the order OH â‰?H < Cl. Generally, there were only small differences among most of the amines studied.

Journal fuer Praktische Chemie (Leipzig) published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, HPLC of Formula: 4543-95-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts