Category: 4410-99-5

Supranovich, Vyacheslav I. published the artcileGeneration of Alkyl Radicals from Thiols via Zinc Thiolates: Application for the Synthesis of gem-Difluorostyrenes, Synthetic Route of 4410-99-5, the publication is Advanced Synthesis & Catalysis (2021), 363(11), 2888-2892, database is CAplus.

Reaction of thiols with α-(trifluoromethyl)styrenes under photocatalytic conditions led to desulfurative allylic fluorine substitution was described. The reaction was performed by treatment of thiols with benzyl zinc chloride to generate zinc thiolates followed by visible light induced desulfurization by means of triphenylphosphine. Radicals formed after the C-S bond cleavage react with the double bond afforded gem-difluorostyrenes.

Advanced Synthesis & Catalysis published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C10H18O4, Synthetic Route of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lee, Seo Yoon published the artcilepH-Dependent interaction mechanism of lignin nanofilms, Recommanded Product: 2-Phenylethanethiol, the publication is Nanoscale (2021), 13(46), 19568-19577, database is CAplus and MEDLINE.

Lignin has been spotlighted as an abundant renewable bioresource for use in material technologies and applications such as biofuels, binders, composites, and nanomaterials for drug delivery. However, owing to its complex and irregular structure, it is difficult to investigate its fundamental interaction mechanism, which is necessary to promote its use. In this study, a surface forces apparatus (SFA) was used to investigate the pH-dependent mol. interactions between a lignin nanofilm and five functionalized self-assembled monolayers (SAMs). The lignin nanofilm adhered most strongly to the amine-functionalized SAM, indicating that the mol. interactions with lignin were mainly electrostatic and cation-π interactions. The force-distance profile between lignin and a methyl-functionalized SAM revealed pH-dependent interactions similar to those between two lignin nanofilms. This finding indicates that the dominant cohesion mechanism is hydrophobic interactions. A quartz crystal microbalance with dissipation was used to investigate the adsorption of free lignin mols. on functionalized SAMs. Lignin mols., which were free in solution, were most effectively adsorbed to the phenyl-functionalized SAM. To investigate whether the nanoscopic interaction forces could be extended to macroscopic properties, the compressive strength of activated carbon-lignin composites prepared at different pH values was evaluated. As the pH increased, the compressive strength decreased owing to the reduced hydrophobic interactions between the activated carbon and lignin, consistent with the SFA results. These quant. results regarding lignin interactions can advance the potential use of lignin as an eco-friendly biomaterial.

Nanoscale published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Barth, Marie-Christin published the artcileSynthesis and characterization of thiocarbonato-linked platinum(IV) complexes, Related Products of alcohols-buliding-blocks, the publication is Dalton Transactions (2022), 51(14), 5567-5576, database is CAplus and MEDLINE.

Herein we show the formation of new oxaliplatin-based platinum(IV) complexes by reaction with DSC-activated thiols via thiocarbonate linkage. Three model complexes based on aliphatic and aromatic thiols, as well as one complex with N-acetylcysteine as biol. active thiol were synthesized. This synthetic strategy affords the expansion of biol. active compounds other than those containing carboxylic, amine or hydroxy groups for coupling to the platinum(IV) center. The complexes were characterized by high-resolution mass spectrometry, NMR spectroscopy (¹H, ¹³C, ¹⁹⁵Pt) and elemental anal. Their biol. behavior was evaluated against two ovarian carcinoma cell lines and their cisplatin-resistant analogs. Remarkably, the platinum(IV) samples show modest in vitro cytotoxicity against A2780 cells and comparable effects against A2780cis cells. Two complexes in particular demonstrate improved activity against SKOV3cis cells. The reduction experiment of complex 8, investigated by UHPLC-HRMS, provides evidence of interesting platinum-species formed during reaction with ascorbic acid.

Dalton Transactions published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Spiliopoulou, Nikoleta published the artcilePhotochemical metal-free aerobic oxidation of thiols to disulfides, SDS of cas: 4410-99-5, the publication is Green Chemistry (2021), 23(1), 546-551, database is CAplus.

A mild, inexpensive and green photochem. approach for the synthesis of both sym. and non-sym. disulfides, using metal-free and environmentally friendly conditions was reported. Utilizing phenylglyoxylic acid as the photoinitiator, common household bulbs as the light source and a simple inorganic salt as the additive, a versatile oxidation of thiols leading to products in excellent yields was described.

Green Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C11H14O4, SDS of cas: 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kawawaki, Tokuhisa published the artcileCreation of High-Performance Heterogeneous Photocatalysts by Controlling Ligand Desorption and Particle Size of Gold Nanocluster, Name: 2-Phenylethanethiol, the publication is Angewandte Chemie, International Edition (2021), 60(39), 21340-21350, database is CAplus and MEDLINE.

Recently, the creation of new heterogeneous catalysts using the unique electronic/geometric structures of small metal nanoclusters (NCs) has received considerable attention. However, to achieve this, it is extremely important to establish methods to remove the ligands from ligand-protected metal NCs while preventing the aggregation of metal NCs. In this study, the ligand-desorption process during calcination was followed for metal-oxide-supported 2-phenylethanethiolate-protected gold (Au) 25-atom metal NCs using five exptl. techniques. The results clearly demonstrate that the ligand-desorption process consists of ligand dissociation on the surface of the metal NCs, adsorption of the generated compounds on the support and desorption of the compounds from the support, and the temperatures at which these processes occurred were elucidated. Based on the obtained knowledge, we established a method to form a metal-oxide layer on the surface of Au NCs while preventing their aggregation, thereby succeeding in creating a water-splitting photocatalyst with high activity and stability.

Angewandte Chemie, International Edition published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Name: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sakthivel, Naga Arjun published the artcileSize Exclusion Chromatography: An Indispensable Tool for the Isolation of Monodisperse Gold Nanomolecules, Recommanded Product: 2-Phenylethanethiol, the publication is Analytical Chemistry (Washington, DC, United States) (2021), 93(8), 3987-3996, database is CAplus and MEDLINE.

Highly monodisperse and pure samples of atomically precise gold nanomols. (AuNMs) are essential to understand their properties and to develop applications using them. Unfortunately, the synthetic protocols that yield a single-sized nanomol. in a single-step reaction are unavailable. Instead, we observe a polydisperse product with a mixture of core sizes. This product requires post-synthetic reactions and separation techniques to isolate pure nanomols. Solvent fractionation based on the varying solubility of different sizes serves well to a certain extent in isolating pure compounds It becomes tedious and offers less control while separating AuNMs that are very similar in size. Here, we report the versatile and the indispensable nature of using size exclusion chromatog. (SEC) as a tool for separating nanomols. and nanoparticles. We have demonstrated the following: (1) the ease of separation offered by SEC over solvent fractionation; (2) the separation of a wider size range (~5-200 kDa or ~1-3 nm) and larger-scale separation (20-100 mg per load); (3) the separation of closely sized AuNMs, demonstrated by purifying Au₁₃₇(SR)₅₆ from a mixture of Au₃₂₉(SR)₈₄, Au₁₄₄(SR)₆₀, Au₁₃₇(SR)₅₆, and Au₁₃₀(SR)₅₀, which could not be achieved using solvent fractionation; (4) the separation of AuNMs protected by different thiolate ligands (aliphatic, aromatic, and bulky); and (5) the separation can be improved by increasing the column length. Mass spectrometry was used for analyzing the SEC fractions.

Analytical Chemistry (Washington, DC, United States) published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liu, Shengping published the artcileNickel-catalyzed oxidative dehydrogenative coupling of alkane with thiol for C(sp³)-S bond formation, SDS of cas: 4410-99-5, the publication is Tetrahedron Letters (2021), 152950, database is CAplus.

A nickel-catalyzed oxidative dehydrogenative coupling reaction of alkanes RH (R = 1-phenylethan-1-yl, cyclohexyl, tetrahydrofuran-2-yl, 1,4-dioxan-2-yl, etc.) with thiols R¹SH (R¹ = 4-methylphenyl, 2-naphthyl, octan-1-yl, benzo[d]thiazol-2-yl, etc.) for the construction of C(sp³)-S bond has been established, affording more than 50 alkyl thioethers RSR¹. Notably, pharmaceutical and agrochems., such as Provigil, Chlorbenside and Pyridaben, were readily synthesized by this approach. The sterically hindered ligand bathocuproine (BC) and disulfide which was formed in situ oxidation of thiol, efficiently avoiding nickel-catalyst poisoning. A set of mechanistic experiments disclose both Ni-catalyzed and Ni-free HAA processes.

Tetrahedron Letters published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, SDS of cas: 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Park, Sohyun published the artcileValidating the Mott Formula with Self-Assembled Monolayer (SAM)-Based Large-Area Junctions: Effect of Length, Backbone, Spacer, Substituent, and Electrode on the Thermopower of SAMs, Formula: C8H10S, the publication is Journal of Physical Chemistry C (2021), 125(36), 20035-20047, database is CAplus.

Understanding how the Seebeck effect of organic thermoelec. devices is associated with the chem. structure of active mols. within the devices is a key goal in organic and mol. thermoelecs. This paper describes a series of phys.-organic studies that investigate structure-thermopower relationships in self-assembled monolayers (SAMs) through measurements of the Seebeck coefficient (S, μV/K) using the eutectic gallium-indium (EGaIn)-based junction technique. Several hypotheses were derived from a transmission function-based simple toy model, the Lorentzian transmission function-based Mott formula. These hypotheses were tested by comparing values of S for simple alkyl and aryl mols. with different structures in terms of backbone, length, spacer, anchor, and substituent, and for different electrodes (Au vs Ag), and by monitoring responses of S to the structural modifications. Exptl. obtained S values were further reconciled with values simulated by the Mott formula and with interfacial electronic structure and mol.-electrode coupling strength, independently measured by UPS and transition voltage spectroscopy.

Journal of Physical Chemistry C published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Formula: C8H10S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yoshikawa, Chisato published the artcileConstruction of 7-diethylaminocoumarins promoted by an electron-withdrawing group, Recommanded Product: 2-Phenylethanethiol, the publication is Chemical & Pharmaceutical Bulletin (2021), 69(7), 608-611, database is CAplus.

The coumarin skeleton has been a focus of attention for many years, and its fluorescence properties vary depending on the substituents. Fluorescent coumarin derivatives I (R = OMe, diethylaminyl; R¹ = (2-phenylethyl)sulfanyl, phenyloxidanyl, (2-phenylethyl)oxidanyl, etc.) are useful tools for many strategies and have been developed for their synthesis. Although 7-diethylaminocoumarins I has excellent fluorescence properties, it is unstable. A facile strategy for the synthesis of 7-diethylaminocoumarin derivatives I by increasing the electrophilicity of the ynone moiety to promote nucleophilic addition reactions and cyclization have been developed. The reaction tolerates a variety of substitutions at the 4-position.

Chemical & Pharmaceutical Bulletin published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C12H15ClO3, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gong, Jun published the artcileIodization-enhanced fluorescence and circularly polarized luminescence for dual-readout probe design, Recommanded Product: 2-Phenylethanethiol, the publication is Sensors and Actuators, B: Chemical (2021), 130610, database is CAplus.

Circularly polarized luminescence (CPL) is a preferential emission from chiral systems. Introducing CPL to traditional small fluorescence probes will greatly enhance selectivity and sensitivity due to avoiding the background fluorescence. Small-mol. probes are practically useful for bioimaging and sensing but always suffer from weak CPL properties. To optimize chiral perturbation, the study of structure-CPL correlation is an urgent necessity. Here, we investigated the influence of 3, 3′-substituent of BINOL on optical properties and found that iodization could significantly enhance the fluorescence quantum yield (Φ_F) and dissymmetry factor (|g_lum|). Based on this finding, we presented a strategy to design dual-readout probes emiting both robust total fluorescence and CPL upon activation. As an application example, we first designed a pair of thiols probes, R/S-P1, with the fluorescence readout showing good linear response to cysteine, and CPL signal displaying significant enhancement with |g_lum| from undetectable value to 0.7 x 10^-3.

Sensors and Actuators, B: Chemical published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts