Category: 4410-99-5

Mamat, Marhaba published the artcileA visible-light-induced thiol addition/aerobic oxidation cascade reaction of epoxides and thiols for the synthesis of β-hydroxylsulfoxides, Safety of 2-Phenylethanethiol, the publication is Organic & Biomolecular Chemistry (2021), 19(45), 9855-9859, database is CAplus and MEDLINE.

A photochem. thiol addition/aerobic oxidation cascade reaction had been developed. This protocol enabled efficient oxidative coupling of epoxides and thiols to access structurally valuable β-hydroxylsulfoxides RSO₂CH₂C(R¹R²)OH [R = 4-MeC₆H₄, 4-ClC₆H₄, 4-MeOC₆H₄, etc.; R¹ = H, Me; R² = Me, Et, CO₂Et, etc.]. A broad range of functional groups were compatible to obtain moderate to good yields of the target products. Mechanistic studies revealed a sequential reaction pathway involving base-promoted thiol addition of thiols to epoxides and visible-light-induced aerobic oxygenation of thioethers.

Organic & Biomolecular Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Safety of 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cheng, Tairan published the artcileCu-catalyzed carboboration of acetylene with Michael acceptors, Category: alcohols-buliding-blocks, the publication is Chemical Science (2022), 13(25), 7604-7609, database is CAplus and MEDLINE.

A copper-catalyzed three-component carboboration of acetylene with B₂Pin₂ and Michael acceptors is reported. In this reaction, a cheap and abundant C2 chem. feedstock, acetylene, was used as a starting material to afford cis-alkenyl boronates bearing a homoallylic carbonyl group. The reaction was robust and could be reliably performed on the molar scale. Furthermore, the resulting cis-alkenyl boronates could be converted to diverse functionalized mols. with ease.

Chemical Science published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Qifeng published the artcileSulfur(IV)-mediated umpolung α-heterofunctionalization of 2-oxazolines, Product Details of C8H10S, the publication is Chemical Science (2022), 13(18), 5164-5170, database is CAplus and MEDLINE.

The α-umpolung of carbonyl compounds significantly expands the boundaries of traditional carbonyl chem. Despite various umpolung methods available today, reversing the inherent reactivity ofcarbonyls still remains a substantial challenge. In this article, the authors report the first use of sulfonium salts, in lieu of well-established hypervalent iodines, for the carbonyl umpolung event. The protocol enables the incorporation of a wide variety of heteroatom nucleophiles into the α-carbon of 2-oxazolines. The success of this investigation hinges on the following factors: (1) the use of sulfoxides, which are abundant, structurally diverse and tunable, and easily accessible, ensures the identification of a superior oxidant namely phenoxathiin sulfoxide for the umpolung reaction; (2) the “assembly/deprotonation” protocol previously developed for rearrangement reactions in the authors’ laboratory was successfully applied here for the construction of α-umpoled 2-oxazolines.

Chemical Science published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C7H16ClNO2, Product Details of C8H10S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Xinglin published the artcileEfficient visible light initiated hydrothiolations of alkenes/alkynes over Ir₂S₃/ZnIn₂S₄: Role of Ir₂S₃, Name: 2-Phenylethanethiol, the publication is Chinese Journal of Catalysis (2021), 42(3), 409-416, database is CAplus.

The hydrothiolations of alkynes/alkenes with thiols is an atom-economic and thus attractive method for the constructions of C-S bonds. Here, Ir₂S₃/ZnIn₂S₄ nanocomposites with varied Ir₂S₃ loadings were obtained by one-pot solvothermal method from ZnCl₂, InCl₃ and thioacetamide with IrCl₃. The loading of Ir₂S₃ on the surface of ZnIn₂S₄ promoted the hydrothiolations of alkenes and alkynes, with an optimum performance observed over 0.5 mol% Ir₂S₃/ZnIn₂S₄ nanocomposite. Based on the studies on the performance of several other cocatalysts (MoS₂, NiS and Pd) loaded ZnIn₂S₄ and the EIS analyses, it was proposed that the superior performance over Ir₂S₃/ZnIn₂S₄ nanocomposite can be ascribed to an improved efficiency on the photogeneration of the thiyl radicals by loading Ir₂S₃ as well as its inactivity for photocatalytic hydrogen evolution, a side reaction in the light-initiated hydrothiolation reaction over ZnIn₂S₄. This study not only demonstrates an efficient and green strategy to synthesize thiolated products under visible light based on semiconductor photocatalysis, but also provides some guidance for the design and development of photocatalytic systems for light-induced organic syntheses.

Chinese Journal of Catalysis published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C12H14BNO2, Name: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liu, Zhongyu published the artcileObservation of Core Phonon in Electron-Phonon Coupling in Au₂₅ Nanoclusters, Name: 2-Phenylethanethiol, the publication is Journal of Physical Chemistry Letters (2021), 12(6), 1690-1695, database is CAplus and MEDLINE.

Temperature-dependent optical properties are of paramount importance for fundamentally understanding the electron-phonon interactions and phonon modes in atomically precise nanocluster materials. In this work, low-temperature optical absorption spectra of the icosahedral [Au₂₅(SR)₁₈]^– nanocluster are measured from room temperature down to liquid helium temperature by adopting a thin-film-based technique. The thin-film measurement is further compared with results from the previous solution-based method. Interestingly, the previously missing core phonon is revealed by a quant. anal. of the film data through peak deconvolution and fitting of the temperature trend with a theor. model. The two lowest-energy absorption peaks (at 1.6 and 1.8 eV) of Au₂₅ are determined to couple with the staple-shell phonon (average energy ~350 cm^-1) in the solution state, but in the solid state these electronic transitions couple with the core phonon (average energy ~180 cm^-1). The suppression of the staple-shell phonon in the solid state is attributed to the intracluster and cluster-matrix interactions.

Journal of Physical Chemistry Letters published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Name: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Dungai published the artcileLiBr-Catalyzed C3-Disulfuration between Indole and N-Dithiophthalimide, Recommanded Product: 2-Phenylethanethiol, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.

A simple, green halide-catalyzed protocol for disulfuration of indole derivatives with N-dithiophthalimides was developed. This C-H disulfide reaction proceeded smoothly at room temperature with economical LiBr as catalyst, providing an effective method for the synthesis of novel unsym. disulfides. A series of 3-dithioindole derivatives were obtained in high yields with good functional group tolerance, moreover, the wide scope of Harpp reagents (aryl, benzyl, primary, secondary, tertiary) confirmed the practicability of this approach.

Journal of Organic Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C2H2N4O2, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Yingwei published the artcileHydrogen Evolution Electrocatalyst Design: Turning Inert Gold into Active Catalyst by Atomically Precise Nanochemistry, Name: 2-Phenylethanethiol, the publication is Journal of the American Chemical Society (2021), 143(29), 11102-11108, database is CAplus and MEDLINE.

Electrocatalytic hydrogen evolution reaction (HER) holds promise in the renewable clean energy scheme. Crystalline Au and Ag are, however, poor in catalyzing HER, and the ligands on colloidal nanoparticles are generally another disadvantage. Herein, we report a thiolate (SR)-protected Au₃₆Ag₂(SR)₁₈ nanocluster with low coverage of ligands and a core composed of three icosahedral (I_h) units for catalyzing HER efficiently. This trimeric structure, together with the monomeric I_h Au₂₅(SR)₁₈^– and dimeric I_h Au₃₈(SR)₂₄, constitutes a unique series, providing an opportunity for revealing the correlation between the catalytic properties and the catalyst′s structure. The Au₃₆Ag₂(SR)₁₈ surprisingly exhibits high catalytic activity at lower overpotentials for HER due to its low ligand-to-metal ratio, low-coordinated Au atoms and unfilled superat. orbitals. The c.d. of Au₃₆Ag₂(SR)₁₈ at -0.3 V vs RHE is 3.8 and 5.1 times that of Au₂₅(SR)₁₈^– and Au₃₈(SR)₂₄, resp. D. functional theory (DFT) calculations reveal lower hydrogen binding energy and higher electron affinity of Au₃₆Ag₂(SR)₁₈ for an energetically feasible HER pathway. Our findings provide a new strategy for constructing highly active catalysts from inert metals by pursuing atomically precise nanoclusters and controlling their geometrical and electronic structures.

Journal of the American Chemical Society published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Name: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Supranovich, Vyacheslav I. published the artcileGeneration of Alkyl Radicals from Thiols via Zinc Thiolates: Application for the Synthesis of gem-Difluorostyrenes, Synthetic Route of 4410-99-5, the publication is Advanced Synthesis & Catalysis (2021), 363(11), 2888-2892, database is CAplus.

Reaction of thiols with α-(trifluoromethyl)styrenes under photocatalytic conditions led to desulfurative allylic fluorine substitution was described. The reaction was performed by treatment of thiols with benzyl zinc chloride to generate zinc thiolates followed by visible light induced desulfurization by means of triphenylphosphine. Radicals formed after the C-S bond cleavage react with the double bond afforded gem-difluorostyrenes.

Advanced Synthesis & Catalysis published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C10H18O4, Synthetic Route of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lee, Seo Yoon published the artcilepH-Dependent interaction mechanism of lignin nanofilms, Recommanded Product: 2-Phenylethanethiol, the publication is Nanoscale (2021), 13(46), 19568-19577, database is CAplus and MEDLINE.

Lignin has been spotlighted as an abundant renewable bioresource for use in material technologies and applications such as biofuels, binders, composites, and nanomaterials for drug delivery. However, owing to its complex and irregular structure, it is difficult to investigate its fundamental interaction mechanism, which is necessary to promote its use. In this study, a surface forces apparatus (SFA) was used to investigate the pH-dependent mol. interactions between a lignin nanofilm and five functionalized self-assembled monolayers (SAMs). The lignin nanofilm adhered most strongly to the amine-functionalized SAM, indicating that the mol. interactions with lignin were mainly electrostatic and cation-π interactions. The force-distance profile between lignin and a methyl-functionalized SAM revealed pH-dependent interactions similar to those between two lignin nanofilms. This finding indicates that the dominant cohesion mechanism is hydrophobic interactions. A quartz crystal microbalance with dissipation was used to investigate the adsorption of free lignin mols. on functionalized SAMs. Lignin mols., which were free in solution, were most effectively adsorbed to the phenyl-functionalized SAM. To investigate whether the nanoscopic interaction forces could be extended to macroscopic properties, the compressive strength of activated carbon-lignin composites prepared at different pH values was evaluated. As the pH increased, the compressive strength decreased owing to the reduced hydrophobic interactions between the activated carbon and lignin, consistent with the SFA results. These quant. results regarding lignin interactions can advance the potential use of lignin as an eco-friendly biomaterial.

Nanoscale published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Barth, Marie-Christin published the artcileSynthesis and characterization of thiocarbonato-linked platinum(IV) complexes, Related Products of alcohols-buliding-blocks, the publication is Dalton Transactions (2022), 51(14), 5567-5576, database is CAplus and MEDLINE.

Herein we show the formation of new oxaliplatin-based platinum(IV) complexes by reaction with DSC-activated thiols via thiocarbonate linkage. Three model complexes based on aliphatic and aromatic thiols, as well as one complex with N-acetylcysteine as biol. active thiol were synthesized. This synthetic strategy affords the expansion of biol. active compounds other than those containing carboxylic, amine or hydroxy groups for coupling to the platinum(IV) center. The complexes were characterized by high-resolution mass spectrometry, NMR spectroscopy (¹H, ¹³C, ¹⁹⁵Pt) and elemental anal. Their biol. behavior was evaluated against two ovarian carcinoma cell lines and their cisplatin-resistant analogs. Remarkably, the platinum(IV) samples show modest in vitro cytotoxicity against A2780 cells and comparable effects against A2780cis cells. Two complexes in particular demonstrate improved activity against SKOV3cis cells. The reduction experiment of complex 8, investigated by UHPLC-HRMS, provides evidence of interesting platinum-species formed during reaction with ascorbic acid.

Dalton Transactions published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts