Category: 4410-99-5

Pramanik, Milan published the artcileSulfur···oxygen interaction-controlled (Z)-selective anti-Markovnikov vinyl sulfides, Category: alcohols-buliding-blocks, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(46), 5698-5701, database is CAplus and MEDLINE.

The sulfur oxygen (S···O) interaction was used herein to obtain (Z)-selective anti-Markovnikov vinyl sulfides from the addition of thiyl radicals to N-aryl propynamides. DFT calculations predicted that S···O interaction originated from the delocalization of the lone-pair of the carbonyl oxygen to the adjacent σ^* orbital of the S atom of C-S.

Chemical Communications (Cambridge, United Kingdom) published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Pramanik, Milan published the artcilet-BuOLi-promoted terminal alkyne functionalizations by aliphatic thiols and alcohols, SDS of cas: 4410-99-5, the publication is Organic & Biomolecular Chemistry (2022), 20(13), 2671-2680, database is CAplus and MEDLINE.

Selective addition of aliphatic thiols or alcs. R¹XH (X = O, R¹ = Me, Et, F₃CCH₂, n-decyl, etc.; X = S, R¹ = i-Bu, PhCH₂, n-dodecyl, 2-furylmethyl, etc.) to N-aryl propiolamides HCCC(O)NHR² (R² = Ph, 2-MeC₆H₄, 3,4-Cl₂C₆H₃, etc.) using lithium tert-butoxide in ethanol as a promoter is described. Mechanistically, it was shown that the reaction proceeds through the generation of a thiyl radical intermediate, and the amide group in N-phenylpropiolamide helps in the activation of the alkyne, which led to thioacetalization via the formation of a (Z)-selective anti-Markovnikov vinyl sulfide. The (Z)-selectivity during the formation of vinyl sulfides was controlled by an intramol. sulfur···oxygen interaction.

Organic & Biomolecular Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, SDS of cas: 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Serusi, Lorenzo published the artcileThe First Highly Enantioselective Synthesis of 3-Sulfinyl-Substituted Isoindolinones Having Adjacent Carbon and Sulfur Stereocenters, Application In Synthesis of 4410-99-5, the publication is Journal of Organic Chemistry (2021), 86(15), 10630-10639, database is CAplus and MEDLINE.

A highly stereoselective access to 3-sulfinyl-substituted isoindolinones was achieved by a tandem organocatalytic addition/cyclization reaction of 2-carbobenzyloxy-N-tosylbenzylidenimine with thiols and succeeding diastereoselective oxidation with MCPBA. First, enantioenriched isoindolinone N,S-acetals was obtained through a dynamic kinetic asym. transformation induced by a bifunctional chiral thiourea organocatalyst. In turn, the newly created carbon stereocenter enabled a high diastereocontrol in the subsequent sulfoxidation Based on DFT calculations, a theor. rationale for the stereoselectivity of the oxidation reaction was also provided.

Journal of Organic Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C13H13N, Application In Synthesis of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Swierczewski, Michal published the artcileDeposition of Extended Ordered Ultrathin Films of Au₃₈(SC₂H₄Ph)₂₄ Nanocluster using Langmuir-Blodgett Technique, Recommanded Product: 2-Phenylethanethiol, the publication is Small (2021), 17(27), 2005954, database is CAplus and MEDLINE.

Langmuir-Blodgett technique is utilized to deposit ultrathin films of Au₃₈(SC₂H₄Ph)₂₄ nanocluster onto solid surfaces such as mica and silicon. The morphologies of the films transferred at various surface pressures within the mono/bi/trilayer regime are studied by at. force microscopy (AFM). The time spent on the water surface before the deposition has a decisive effect on the final ordering of nanoclusters within the network and is studied by fast AFM, X-ray reflectivity, and grazing-incidence wide-angle X-ray scattering.

Small published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C11H8O3, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cohen, Yair published the artcileDirected Regioselective Carbometallation of 1,2-Dialkyl-Substituted Cyclopropenes, Computed Properties of 4410-99-5, the publication is Angewandte Chemie, International Edition (2021), 60(50), 26368-26372, database is CAplus and MEDLINE.

A regio- and diastereoselective copper-catalyzed carbomagnesiation of 1,2-dialkylated cyclopropenes I (R = H, Me; R¹ = Me, Et; R² = OH, Ph, OBn, etc.; R³ = Me, Ph, CH₂CH(CH₃)₂, etc.; n = 1-5) is reported. The regioselectivity is controlled by a subtle tethered Lewis basic moiety. The chelating moieties allow the differentiation between two electronically tantamount organometallic intermediates. Further functionalization grants access to polysubstituted stereodefined cyclopropanes II (R⁴ = H, allyl) and III bearing up to five alkyl groups.

Angewandte Chemie, International Edition published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Computed Properties of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chatterjee, Sayanti published the artcileHydroxylamine-Derived Reagent as a Dual Oxidant and Amino Group Donor for the Iron-Catalyzed Preparation of Unprotected Sulfinamides from Thiols, Computed Properties of 4410-99-5, the publication is Angewandte Chemie, International Edition (2021), 60(2), 758-765, database is CAplus and MEDLINE.

An iron catalyzed reaction for the selective transformation of thiols (-SH) to sulfinamides (-SONH₂) by a direct transfer of -O and free -NH₂ groups has been developed. The reaction operates under mild conditions using a bench stable hydroxylamine derived reagent, exhibits broad functional group tolerance, is scalable and proceeds without the use of any precious metal catalyst or addnl. oxidant. This novel, practical reaction leads to the formation of two distinct new bonds (S=O and S-N) in a single step to chemoselectively form valuable, unprotected sulfinamide products. Preliminary mechanistic studies implicate the role of the alc. solvent as an oxygen atom donor.

Angewandte Chemie, International Edition published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Computed Properties of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dong, Si published the artcileFunctional Amphiphilic Poly(2-oxazoline) Block Copolymers as Drug Carriers: the Relationship between Structure and Drug Loading Capacity, Recommanded Product: 2-Phenylethanethiol, the publication is Chinese Journal of Polymer Science (2021), 39(7), 865-873, database is CAplus.

Poly(2-oxazoline) (POx) is a kind of polymeric amides that can be viewed as conformational isomers of polypeptides with excellent cyto- and hemo-compatibility, and is promising to be used as drug carriers. However, the drug loading capacity (DLC) of POx for many drugs is still low except several hydrophobic ones including paclitaxel (PTX). Herein, we prepared a series of amphiphilic POx block copolymers with various functional groups, and investigated the relationship between functional structures and the DLC. Functional POxs with benzyl, carboxyl, and amino groups in the side-chain were synthesized based on a poly(2-methyl-2-oxazoline)-block-poly(2-butyl-2-oxazoline-co-2-butenyl-2-oxazoline) (PMeOx-P(nBuOx-co-ButenOx), PMBEOx) precursor, followed by click reaction between vinyl and the 2-phenylethanethiol, thioglycolic acid and cysteamine. Using thin-film hydration method, eight commonly used drugs with various characteristics were encapsulated within these functional POx polymers. We found that amine-containing drugs were more easily encapsulated by POx with carboxyl groups, while amine functionalities in POx enhanced the loading capacity of drugs with carboxyl groups. In addition, ;π;π interactions resulted in enhanced DLC of most drugs, except several hydrophobic drugs with aromatic to total carbon ratios less than 0.5. In general, we could successfully encapsulate all the selected drugs with a DLC% over 10% using properly selected functional POxs. The above results confirm that the DLC of polymeric carriers can be adjusted by modifying the functional groups, and the prepared series of functional POxs provide an option for various drug loadings.

Chinese Journal of Polymer Science published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Du, Xiangsha published the artcileSingle-electron charging and ultrafast dynamics of bimetallic Au_144-xAg_x(PET)₆₀ nanoclusters, Application of 2-Phenylethanethiol, the publication is Nano Research (2022), 15(9), 8573-8578, database is CAplus.

Alloying is an important strategy in tailoring the functionality of materials. In metal nanoclusters (NCs), the introduction of a heterometal leads to alloy nanoclusters that often outperform the homometal ones in terms of the phys. and chem. properties. In this work, a series of four M₁₄₄(PET)₆₀ alloy NCs (where, M = Au/Ag, PET = -SCH₂CH₂Ph) are synthesized and characterized. The silver doping into the homogold template (Au₁₄₄) leads to more prominent optical absorption features in the steady-state spectrum in the visible range. Femtosecond transient absorption spectroscopy reveals the effect of Ag doping on the electronic relaxation dynamics compared to Au₁₄₄ and the pump fluence independent dynamics. Electrochem. results reflect a narrowing of HOMO-LUMO gap (Eg) induced by Ag doping. A temperature dependence of the single-electron charging is also observed for the series of alloy NCs, in which the E_g values of the alloy NCs enlarge as the temperature decreases, which is characteristic of semiconducting behavior. [graphic not available: see fulltext]

Nano Research published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Application of 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Nie, Shaozhen published the artcileEnantioselective Hydrothiolation: Diverging Cyclopropenes through Ligand Control, Category: alcohols-buliding-blocks, the publication is Journal of the American Chemical Society (2021), 143(16), 6176-6184, database is CAplus and MEDLINE.

In this article, we advance Rh-catalyzed hydrothiolation through the divergent reactivity of cyclopropenes. Cyclopropenes undergo hydrothiolation to provide cyclopropyl sulfides such as I or allylic sulfides such as II. The choice of bisphosphine ligand dictates whether the pathway involves ring-retention or ring-opening. Mechanistic studies reveal the origin for this switchable selectivity. Our results suggest the two pathways share a common cyclopropyl-Rh(III) intermediate. Electron-rich Josiphos ligands promote direct reductive elimination from this intermediate to afford cyclopropyl sulfides in high enantio- and diastereoselectivities. Alternatively, atropisomeric ligands (such as DTBM-BINAP) enable ring-opening from the cyclopropyl-Rh(III) intermediate to generate allylic sulfides with high enantio- and regiocontrol.

Journal of the American Chemical Society published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Min published the artcileCooperative Gold/Zinc-catalyzed Cascade Approach to Tryptophan Derivatives from N-arylhydroxylamines and Alkynes, Related Products of alcohols-buliding-blocks, the publication is Asian Journal of Organic Chemistry (2022), 11(4), e202200054, database is CAplus.

A cooperative gold/zinc catalyzed strategy for the synthesis of tryptophan derivatives from easily prepared N-arylhydroxylamines and chiral amino acid tethered alkynes with high efficiency has been developed. The structurally diverse tryptophan derivatives including pharmaceutical relevant mols. can be readily prepared by this method. This tandem transformation starts from acyclic simple materials rather than the existing methods by modifying indole skeletons.

Asian Journal of Organic Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C11H8O3, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts