Category: 4410-99-5

Xiao, Qian published the artcileDirecting-Group-Assisted Markovnikov-Selective Hydrothiolation of Styrenes with Thiols by Photoredox/Cobalt Catalysis, Safety of 2-Phenylethanethiol, the publication is Organic Letters (2021), 23(9), 3604-3609, database is CAplus and MEDLINE.

In contrast with the well-developed radical thiol-ene reaction to access anti-Markovnikov-type products, the research on the catalytic Markovnikov-selective hydrothiolation of alkenes is very restricted. Because of the catalyst poisoning of metal catalysts by organosulfur compounds, limited examples of transition-metal-catalyzed thiol-ene reactions have been reported. However, in this work, a directing-group-assisted hydrothiolation of styrenes with thiols by photoredox/cobalt catalysis is found to proceed smoothly to afford Markovnikov-type sulfides with excellent regioselectivity.

Organic Letters published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Safety of 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Jeon, Minseok published the artcileStereoselective Synthesis of Cyclohexane Derivatives: Tandem Lithium Iodide Mediated Intramolecular Conjugate Addition of Thiols to α,β-Bisenones, Synthetic Route of 4410-99-5, the publication is Synthesis (2022), 54(12), 2865-2875, database is CAplus.

A tandem intramol. conjugate addition reaction was conducted with α,β-bisenones as selected Michael acceptors which were converted into 1,2,3-trisubstituted six-membered rings in the presence of activated sulfur nucleophiles. The products were obtained in good to excellent yields (maximum yield: 99%). Various substituted α,β-bisenones and sulfur nucleophiles were examined to understand the substrate scope of the reaction. Only one diastereomer was isolated, as lithium iodide mediated enolate trapping reactions improve the stereoselectivity of reactions involving 1,2,3-trisubstituted cyclohexanes.

Synthesis published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Synthetic Route of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wen, Shang-Pin published the artcileRAFT miniemulsion polymerisation of benzyl methacrylate using non-ionic surfactant, Formula: C8H10S, the publication is Polymer Chemistry (2021), 12(14), 2122-2131, database is CAplus.

Miniemulsion polymerization has become widely recognized as a versatile and efficient strategy to prepare well-defined polymer latexes. In this article, we report the synthesis of poly(benzyl methacrylate) (PBzMA) latexes via reversible addition-fragmentation chain-transfer (RAFT) mediated miniemulsion polymerization using non-ionic Lutensol TO 20 surfactant. The influence of hydrophobe, initiator, and RAFT agent on particle diameter, particle number, rate of polymerization, and molar mass were investigated systematically. In all cases well-controlled RAFT polymerizations were observed, as indicated by kinetic studies and GPC anal. Higher concentrations of hexadecane lead to an increase in the of number of particles per unit volume and a decrease in PBzMA latex diameter The rate of polymerization with respect to initiator concentration follows a power-law relationship R_p α [initiator]^1/2 but only negligible differences in molar mass, molar mass dispersity, and particle diameter values were observed for a range of initiator concentrations Targeting lower PBzMA degrees of polymerization increases the overall rate of polymerization and latex diameter

Polymer Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C21H20BrNO4S, Formula: C8H10S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shi, Yao published the artcileComputational Chemistry-Assisted Highly Selective Radical Cascade Cyclization of 1,6-Enynes with Thiols: Access to Sulfur-Substituted 4-Enyl-2-Pyrrolidones, Quality Control of 4410-99-5, the publication is Journal of Organic Chemistry (2022), 87(15), 9479-9487, database is CAplus and MEDLINE.

In this study, an efficient method for the synthesis of sulfur-substituted 4-enyl-2-pyrrolidones I (R¹ = H, 2-Me, 2-Br, 3-Cl, etc.; R² = H, 4-Me; R³ = 4-methylphenyl, (2-chlorophenyl)methyl, furan-2-ylmethyl, etc.) was successfully developed through AIBN-promoted highly selective 5-exo-dig radical cascade cyclization of 1,6-enynes II with sulfur R³SH sources with the aid of theor. and computational chem. This protocol enables the first practical and green synthesis of an array of 4-enyl-2-pyrrolidones I in moderate-to-good yields with broad substrate scopes and high regioselectivities (>20:1). Moreover, excellent stereoselectivities have also been achieved (up to >20:1, Z/E). Most interestingly, when the sulfur source is electron-rich thiophenol, reverse stereoselectivities were discovered. In addition, the control experiments indicate that the cascade cyclization is realized by radical reactions, and the detailed reaction mechanism and regioselectivities have also been explained by theor. studies.

Journal of Organic Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C17H14F3N3O2S, Quality Control of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Yiling published the artcileAmphiphilic polymer-encapsulated Au nanoclusters with enhanced emission and stability for highly selective detection of hypochlorous acid, Recommanded Product: 2-Phenylethanethiol, the publication is RSC Advances (2021), 11(24), 14678-14685, database is CAplus and MEDLINE.

It is of vital importance to develop probes to monitor hypochlorous acid (HClO) in biol. systems as HClO is associated with many important physiol. and pathol. processes. Metal nanoclusters (NCs) are promising luminescent nanomaterials for highly reactive oxygen species (hROS) detection on the basis of their strong reaction ability with hROS. However, metal NCs typically can respond to most common hROS and are susceptible to etching by biothiols, hindering their application in the construction of effective HClO probes. Herein, we proposed a strategy to develop a nanoprobe based on Au NCs for highly sensitive and selective detection of HClO. We synthesized luminescent benzyl mercaptan-stabilized Au NCs and encapsulated them with an amphiphilic polymer (DSPE-PEG). After encapsulation, an obvious emission enhancement and good resistance to the etching by biothiols for Au NCs were achieved. More importantly, the DSPE-PEG encapsulated Au NCs can be used as a nanoprobe for detection of HClO with good performance. The luminescence of the Au NCs was effectively and selectively quenched by HClO. A good linear relationship with the concentration of HClO in the range of 5-35 μM and a limit of detection (LOD) of 1.4 μM were obtained. Addnl., this nanoprobe was successfully used for bioimaging and monitoring of HClO changes in live cells, suggesting the application potential of the as-prepared amphiphilic polymer-encapsulated Au NCs for further HClO-related biomedical research.

RSC Advances published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Nie, Xingliang published the artcileIntroducing A New Class of Sulfonyl Fluoride Hubs via Radical Chloro-Fluorosulfonylation of Alkynes, Name: 2-Phenylethanethiol, the publication is Angewandte Chemie, International Edition (2021), 60(40), 22035-22042, database is CAplus and MEDLINE.

A new and powerful class of sulfonyl fluoride hubs, β-chloro alkenylsulfonyl fluorides (BCASF) (E)/(Z)-RC(R¹)=CHS(O)₂F (R = n-Pr, Ph, naphthalen-2-yl, cyclohexyl, thiophen-3-yl, etc.; R¹ = Cl, Ph, pyrrolidin-1-yl, thiophen-3-yl, etc.), which can be constructed via radical chloro-fluorosulfonyl difunctionalization of alkynes RCCR¹ under photoredox conditions was introduced. BCASF mols. exhibit versatile reactivities and well undergo a series of transformations at the chloride site while keeping the sulfonyl fluoride group intact, including reduction, Suzuki coupling, Sonogashira coupling, as well as nucleophilic substitution with various nitrogen, oxygen, and sulfur nucleophiles. By using BCASF as a synthetic hub, a wide range of sulfonyl fluorides becomes readily accessible, such as cis alkenylsulfonyl fluorides, dienylsulfonyl fluorides, and ynenylsulfonyl fluorides, which are challenging or even not possible to synthesize before with the known methods. Moreover, further application of BCASF to the late-stage modification of peptides and drugs is also demonstrated.

Angewandte Chemie, International Edition published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Name: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Pan, Dandan published the artcilePd-Catalyzed Intermolecular Transthiolation of Ar-OTf Using Methyl 3-(Methylthio) Propanoate as a Thiol Surrogate, Application In Synthesis of 4410-99-5, the publication is European Journal of Organic Chemistry (2021), 2021(33), 4616-4619, database is CAplus.

A method for the odorless synthesis of unsym. sulfides ArSR¹ [Ar = naphth-1-yl, 3-NCC₆H₄, 4-F₃CSC₆H₄, etc.; R¹ = Me, Bn, CH₂CH₂Ph, etc.] via Csp²-O and Csp³-S bond activation was presented. Using Me 3-(methylthio) propanoate as a MeSH surrogate, a series of substituted aryl Me sulfides have been obtained in moderate to good yields. This catalytic protocol could also tolerated Me 3-(methylthio)propionate derivatives to afford the corresponding aryl sulfides.

European Journal of Organic Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Application In Synthesis of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gasior, Robert published the artcileKey Aroma Compounds in Roasted White Koluda Goose, Recommanded Product: 2-Phenylethanethiol, the publication is Journal of Agricultural and Food Chemistry (2021), 69(21), 5986-5996, database is CAplus and MEDLINE.

Aroma-active compounds in the roasted leg meat of White Koluda goose were assayed by gas chromatog.-olfactometry, using aroma extract dilution anal. and solvent-assisted flavor evaporation Quantitation, recombination-omission tests, and sensory evaluation were carried out. Thirty aroma compounds, for which odor activity values (OAVs) were calculated and for which the flavor dilution factors were greater than or equal to 1, were identified. The concentration of aroma compounds ranged from 0.06 to 633 (μg/kg). The highest OAVs (>1024) were for 2-furfurylthiol, 2-acetyl-1-pyrroline, and 1-octen-3-one. Nine key aroma compounds were: 2-furfurylthiol, 2-acetyl-2-thiazoline, 1-octen-3-one, 2-phenylethanethiol, 4,5-dimethyl-3-hydroxy-2(5H)-furanone, 4-hydroxy-2,5-dimethyl-3(2H)-furanone, (E,E)-2,4-decadienal, 2-acetyl-1-pyrroline, and 3-(methylthio)propanal. The intensity of the dominating roasted, meaty/broth, and fatty notes in the recombination model consisting of the key odorants were rated (10-point scale) at 4.6-5.8 points, relative to the original roasted goose (5.2-6.2). The aroma compounds defined predominantly the meaty, roasted, and fatty flavors during the descriptive sensory evaluation of the roasted goose meat.

Journal of Agricultural and Food Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liu, Ye published the artcileInfluence of the Electronic Properties of the Ligand on the Photoelectrochemical Behavior of Au₂₅ Nanocluster-Sensitized TiO₂ Photoanode, Category: alcohols-buliding-blocks, the publication is Journal of Physical Chemistry C (2022), 126(4), 1778-1784, database is CAplus.

Atomically precise metal nanoclusters (NCs) have recently emerged as a new class of bifunctional (photoactive and catalytically active) photosensitizers in light energy conversion applications. Despite the size and alloy effects of NCs, no effort has been made to elucidate how the protecting ligand affects the photoelectrochem. of the NC-sensitized photoelectrodes. With a nanoporous TiO₂ array as model support, Au₂₅ NCs protected by various thiol-bearing ligands have been used to prepare four different photoanodes. It is revealed that a subtle change of the ligand from an alkanethiol to an aromatic thiol facilitates the charge transfer between the NC and TiO₂, which in turn improves the photoelectrochem. performance of the corresponding photoanode by at least 6 times. This new insight highlights the importance of the electronic properties of the ligand on the design of more efficient NC-sensitized photoelectrodes.

Journal of Physical Chemistry C published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Rybicka-Jasinska, Katarzyna published the artcilePorphyrins as Promising Photocatalysts for Red-Light-Induced Functionalizations of Biomolecules, Recommanded Product: 2-Phenylethanethiol, the publication is ACS Organic & Inorganic Au, database is CAplus.

Red-light enables deeper material penetration, which is important for biol. applications and has consequences for chem. synthesis. Therefore, the search for new photocatalysts that absorb in this region is crucial. Despite the undeniable utility of porphyrins in blue- and green-light-induced energy- and electron-transfer processes, they are also perfectly suited for red-light applications. Herein, we describe free-base porphyrins as photoredox catalysts for red-light-induced organic transformations. They can act as both photooxidants and photoreductants and can accomplish the synthesis of biaryls once merged with Pd-catalysis. The developed methodol. holds promise for broader applications, as the heme-based protoporphyrin is used as a photocatalyst and reactions can be realized in aqueous conditions.

ACS Organic & Inorganic Au published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Recommanded Product: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts