Category: 42822-86-6

Plohl, Olivija published the artcileMesoporous silica nanoparticles modified with N-rich polymer as a potentially environmentally-friendly delivery system for pesticides, Quality Control of 42822-86-6, the main research area is mesoporous silica nanoparticle nitrogen polymer pesticide.

The focus of the article is on the design of environmentally-friendly nanocarriers for improved controlled pesticide release, which have low environmental toxicity and nitrogen elemental composition as the most important components of fertilizers. In this study, a novel delivery system was developed for post-loading a biopesticide to mesoporous silica nanoparticles (MeSiNPs) functionalized with N-rich derived polymer. Initially, MeSiNPs were synthesized by the template-assisted method, which yielded MeSiNPs in the nm range, together with highly ordered mesoporous channels with a pore size of 2.9 nm. Subsequently, the water-soluble branched polyethyleneimine (bPEI) was derived systematically with epoxy organosilicate, and functionalized on MeSiNPs to create a source of N-nutrients. The carefully designed novel nano-carrier was analyzed by several physicochem. and structural analyses, which confirmed the successful attachment of the derived bPEI to MeSiNPs. Further, the novel nano-synthesized system was used as a delivery for the model biopesticide citridiol. The loading efficiency of citridiol in/on MeSiNPs@bPEI was 19%, while the loading capacity of citridiol was proven to be 5 mg biopesticide/1 mg MeSiNPs@bPEI. The MeSiNPs@bPEI with loaded citridiol was investigated for kinetic release. The system showed a fast initial release behavior in the first 300 min, which was continued by slow release behavior and started to reach equilibrium after 10 days. It has been shown that the MeSiNPs@bPEI showed an excellent potential for use in agrochem. applications, not only as a nanocarrier for controlled and slow pesticide release, but may also act as a soil improver by providing Si and N as key nutrient sources.

Microporous and Mesoporous Materials published new progress about Biopesticides. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Quality Control of 42822-86-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Miro Specos, Maria M. published the artcileApplication of microencapsulated biopesticides to improve repellent finishing of cotton fabrics, Computed Properties of 42822-86-6, the main research area is microencapsulated biopesticide repellent finishing cotton fabric.

Insect repellent textiles are currently being investigated as a complementary tool to control disease vectors, such as mosquitoes. The application of microencapsulated biopesticides to textiles is a promising low-toxicity alternative to other control methods, as microcapsules may prolong the release of the repellent agent. In this work, microcapsules containing two biopesticides, namely citronella essential oil and citriodiol were prepared and applied to cotton textiles using a variety of techniques. The aim of this work was to evaluate these functional textiles to select the most efficient, durable systems. Citriodiol-treated cotton presented a prolonged durability, and 100% repellency could be achieved for more than 30 days after padding onto cotton fabrics. It has to be pointed out that all these repellent textiles have been obtained by scalable, low-cost methods which would require no addnl. investment for textile finishing industries.

Journal of the Textile Institute published new progress about Biopesticides. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Computed Properties of 42822-86-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhu, Junwei published the artcileAdult repellency and larvicidal activity of five plant essential oils against mosquitoes, Quality Control of 42822-86-6, the main research area is plant essential oil insecticide repellent Aedes Culex.

The larvicidal activity and repellency of 5 plant essential oils-thyme oil, catnip oil, amyris oil, eucalyptus oil, and cinnamon oil-were tested against 3 mosquito species: Aedes albopictus, A. aegypti, and Culex pipiens pallens. Larvicidal activity of these essentials oils was evaluated in the laboratory against 4th instars of each of the 3 mosquito species, and amyris oil demonstrated the greatest inhibitory effect with LC50 values in 24 h of 58 μg/mL (LC90 = 72 μg/mL) for A. aegypti, 78 μg/mL (LC90 = 130 μg/mL) for A. albopictus, and 77 μg/mL (LC90 = 123 μg/mL) for C. pipiens pallens. The topical repellency of these selected essential oils and deet against laboratory-reared female blood-starved A. albopictus was examined Catnip oil seemed to be the most effective and provided 6-h protection at both concentrations tested (23 and 468 μg/cm2). Thyme oil had the highest effectiveness in repelling this species, but the repellency duration was only 2 h. The applications using these natural product essential oils in mosquito control are discussed.

Journal of the American Mosquito Control Association published new progress about Aedes aegypti. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Quality Control of 42822-86-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Paluch, Gretchen E. published the artcileAmyris and Siam-wood essential oils: insect activity of sesquiterpenes, Quality Control of 42822-86-6, the main research area is insecticide Amyris Fokienia essential oil.

Recent investigations on the sesquiterpene-rich Amyris (Amyris balsamifera) and Siam-wood (Fokienia hodginsii) essential oils revealed significant arthropod repellency and toxicity responses. Amyris essential oil and 1 of its major components, elemol, were evaluated in laboratory bioassays and identified as effective mosquito repellents, specifically characterized by high levels of contact and minimal spatial repellency. Mosquito responses to catnip (Nepeta cataria) essential oil are characterized with high spatial activity, but lack significant contact repellency. Sampling within the static-air bioassay chamber with solid-phase microextraction provided measurements of the relative concentration and distribution of volatiles. These results supported the differences observed in repellency between essential oil treatments. Essential oil mixtures containing both spatial (catnip) and contact (Amyris) repellents were made and showed high levels of residual control via both modes of action. Siam-wood essential oil scored high in both spatial and contact efficacy against mosquitoes. Observations during this study included signs of toxicity. Two of the primary components of Siam-wood essential oil were tested for 24-h house fly (Musca domestica) topical mortality. Transnerolidol and fokienol were found to possess similar insecticidal activity (topical LD50 values ranged 0.17-0.21 μmol/fly). Amyris essential oil was selected for addnl. testing with brown dog ticks (Rhipicephalus sanguineus) in a barrier repellency assay. Individuals were observed repeatedly avoiding and moving away from surfaces treated with Amyris essential oil.

ACS Symposium Series published new progress about Aedes aegypti. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Quality Control of 42822-86-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pridgeon, Julia W. published the artcileToxicity comparison of eight repellents against four species of female mosquitoes, Synthetic Route of 42822-86-6, the main research area is mosquito insecticide.

The relative toxicities of 8 repellents (DMP, Rutgers 612, DEET, IR3535, Picardin, PMD, AI3-35765, and AI3-37220) were evaluated by topical application against females of Aedes aegypti, Culex quinquefasciatus, Anopheles quadrimaculatus, and Anopheles albimanus. Based on 24-h LD50 values, the most toxic repellent against all 4 mosquito species was AI3-37220, with values of 0.25, 0.20, 0.16, and 0.11 μg/mg for the listed 4 mosquito species, resp. The least toxic of the 8 repellents tested was DMP, with LD50 values of 5.40, 4.72, 2.50, and 1.83 μg/mg, resp. Based on the 24-h LD50 values, A. albimanus was the most susceptible species. The findings of the study reported herein provide a comprehensive examination of the toxicities of 4 currently used, 2 formerly used, and 2 exptl. repellents against 4 mosquito species.

Journal of the American Mosquito Control Association published new progress about Aedes aegypti. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Synthetic Route of 42822-86-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Feaster, John E. published the artcileDihydronepetalactones deter feeding activity by mosquitoes, stable flies, and deer ticks, Product Details of C10H20O2, the main research area is dihydronepetalactone insect repellent Aedes Anopheles Stomoxys Nepeta oil.

The essential oil of catmint, Nepeta cataria L., contains nepetalactones, that, on hydrogenation, yield the corresponding dihydronepetalactone (DHN) diastereomers. The DHN diastereomer {(4R,4aR,7S,7aS)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one, DHN 1} was evaluated as mosquito repellent, as was the mixture of diastereomers {mostly (4S,4aR,7S,7aR)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one, DHN 2} present after hydrogenation of catmint oil itself. The repellency of these materials to Aedes aegypti L. and Anopheles albimanus Wiedemann mosquitoes was tested in vitro and found to be comparable to that obtained with the well-known insect repellent active ingredient N,N-diethyl-3-methylbenzamide (DEET). DHN 1 and DHN 2 also repelled the stable fly, Stomoxys calcitrans L., in this study. DHN 1, DHN 2, and p-menthane-3,8-diol (PMD), another natural monoterpenoid repellent, gave comparable levels of repellency against An. albimanus and S. calcitrans. Laboratory testing of DHN 1 and DHN 2 using human subjects with An. albimanus mosquitoes was carried out. Both DHN 1 and DHN 2 at 10% (wt:vol) conferred complete protection from bites for significant periods of time (3.5 and 5 h, resp.), with DHN2 conferring protection statistically equivalent to DEET. The DHN 1 and DHN 2 diastereomers were also efficacious against black-legged tick (Ixodes scapularis Say) nymphs.

Journal of Medical Entomology published new progress about Aedes aegypti. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Product Details of C10H20O2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xu, Pingxi published the artcileDEET and other repellents are inhibitors of mosquito odorant receptors for oviposition attractants, SDS of cas: 42822-86-6, the main research area is Culex Aedes Anopheles DEET odorant receptor oviposition attractant; CquiOR2; CquiOR21; CquiOR37; CquiOR99; Inhibitor; Outward current.

In addition to its primary function as an insect repellent, DEET has many “”off-label”” properties, including a deterrent effect on the attraction of gravid female mosquitoes. DEET neg. affects oviposition sites. While deorphanizing odorant receptors (ORs) using the Xenopus oocyte recording system, we have previously observed that DEET generated outward (inhibitory) currents on ORs sensitive to oviposition attractants. Here, we systematically investigated these inhibitory currents. We recorded dose-dependent outward currents elicited by DEET and other repellents on ORs from Culex quinquefasciatus, Aedes aegypti, and Anopheles gambiae. Similar responses were observed with other plant-derived and plant-inspired compounds, including Me jasmonate and Me dihydrojasmolate. Inward (regular) currents elicited by skatole upon activation of CquiOR21 were modulated when this oviposition attractant was coapplied with a repellent. Compounds that generate outward currents in ORs sensitive to oviposition attractants elicited inward currents in a DEET-sensitive receptor, CquiOR136. The best ligand for this receptor, Me dihydrojasmolate, showed repellency activity but was not as strong as DEET in our test protocol.

Insect Biochemistry and Molecular Biology published new progress about Aedes aegypti. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, SDS of cas: 42822-86-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Goodyer, Larry published the artcileCharacterisation of actions of p-menthane-3,8-diol repellent formulations against Aedes aegypti mosquitoes, Formula: C10H20O2, the main research area is menthane Aedes aegypti repellent formulation; DEET; PMD; half-life; longevity; mosquito; repellent.

Characterization of mosquito repellents using arm-in-cage tests are performed by assessing the 95% ED (ED95), half-life and complete protection time (CPT). This study fully characterizes these properties for p-menthane-3,8-diol (PMD), which has not been widely studied, and a long-acting formulation containing a PMD-vanillin composite. A series of arm-in-cage tests against Aedes aegypti (Diptera: Culicidae) mosquitoes were devised using 6 volunteers to estimate CPT or 10 to estimate the ED95 and half-lives for three repellents: 20% N,N-diethyl-3-methylbenzamide (DEET), 30% PMD and a novel 30% PMD-vanillin formulation. Non-linear regression anal. was used to characterize the relationship between applied dose and CPT. PMD and DEET showed a very similar log dose relationship to CPT; however, the PMD-vanillin formulation exhibited a sigmoidal ′S-shaped′ relationship. This resulted in a 1.5-fold higher CPT for PMD-vanillin compared with that of 20% DEET when applied at a dose of 1.6 mg/cm2, but little difference was observed at lower doses of 0.8-1 mg/cm2. The ED95 value for the 30% PMD and PMD-vanillin formulations were 0.25 and 0.24 mg/cm2, resp., these being higher than that for 20% DEET (0.09 mg/cm2). The half-lives for 30% PMD and 20% DEET were similar (2.23 vs. 2.74 h), but longer for the PMD-vanillin formulations (3.8 h). A full characterization for other repellent formulations, particularly those claiming extended longevity, should be conducted in order to identify differences at various applied doses.

Transactions of the Royal Society of Tropical Medicine and Hygiene published new progress about Aedes aegypti. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Formula: C10H20O2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Drapeau, Jeremy published the artcileEffective insect repellent formulation in both surfactantless and classical microemulsions with a long-lasting protection for human beings, Product Details of C10H20O2, the main research area is Aedes insect repellent formulation menthanediol.

The aim of this work is to develop a new generation of repellent products with a long-lasting protection based on a natural component, para-menthane-3,8-diol (PMD). The active is first rendered soluble in a surfactantless microemulsion (H2O/iPrOH/PMD) and then in classical microemulsions. The presence of self-associated nanostructures is detected by dynamic light scattering (DLS). A synergetic system of surfactants (Cremophor RH40 and Texapon N70) is used. Addnl., 2-ethylhexane-1,3-diol and Et (-)-(S)-lactate are incorporated. The final product contains, as main components, 46% of H2O, 25% of iPrOH, 20% of non-H2O-soluble PMD, and only 4% of surfactants. Investigations of lasting protection on human volunteers are carried out using a cage test bioassay protocol and Aedes aegypti mosquitoes. A complete protection of 315 min is found on the test persons using the surfactantless microemulsion. An extension is observed with the final formulation to reach a mean of complete protection of 385 min. This study demonstrates that alternative formulations using a natural active instead of synthetic chems. like N,N-diethyl-m-methylbenzamide (DEET) can be efficient for human protection against mosquitoes.

Chemistry & Biodiversity published new progress about Aedes aegypti. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Product Details of C10H20O2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Api, A. M. published the artcileResearch Institute for Fragrance Materials fragrance ingredient safety assessment, 2-Hydroxy-α,α,4-trimethylcyclohexanemethanol, CAS Registry Number 42822-86-6, Category: alcohols-buliding-blocks, the main research area is RIFM fragrance ingredient safety hydroxytrimethylcyclohexanemethanol.

Research Institute for Fragrance Materials (RIFM)’s Expert Panel concludes that this material is safe under the limits described in this safety assessment. This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization, as well as environmental safety.

Food and Chemical Toxicology published new progress about Chemical safety. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts