Category: 42142-52-9

42142-52-9, Name is 3-(Methylamino)-1-phenylpropan-1-ol, molecular formula is C10H15NO, belongs to alcohols-buliding-blocks compound, is a common compound. In a patnet, author is Xia, Chenlan, once mentioned the new application about 42142-52-9, Application In Synthesis of 3-(Methylamino)-1-phenylpropan-1-ol.

Free fatty acids responsible for characteristic aroma in various sauced-ducks

To investigate the effects of various duck sources on the lipid oxidation and aroma flavor of sauced-ducks, Mallard (ML), Sheldrake (SD), Muscovy (MC), and Cherry-Valley (CV) ducks were used in sauced-duck processing. The results showed significantly different thiobarbituric acid reactive substances (TBARS) values of the four samples (SD 0.05), while the contents of unsaturated fatty acids (UFAs) were ML SD/CV > MC (p < 0.05). Altogether, 105 volatile flavor compounds were detected in sauced-ducks, including acids, alcohols, aldehydes, ketones, esters, hydrocarbons, furans, nitrogen compounds, and others. The volatile compounds were observed differentially composed in the four products, and nineteen potential characteristic biomarkers were explored. The correlation analysis indicated that the characteristic aroma flavor of sauced ducks were significantly associated with specific free fatty acids. These information are useful for learning aroma formation and meat selection and identification in duck products. If you¡¯re interested in learning more about 42142-52-9. The above is the message from the blog manager. Application In Synthesis of 3-(Methylamino)-1-phenylpropan-1-ol.

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In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 42142-52-9 as follows., 42142-52-9

To a solution of 25 g N-methyl-3-phenyl-3-hydroxyphenyl propylamine in hexamethylphosphorous triamide and 19 g potassium f-butoxide at 50-600C was charged 50 g of 2-flourotoluene and the mixture was heated to 105-1100C. The reaction was maintained for 19-20 hours. After the completion of the reaction (monitored by TLC) there were charged 250 ml of water followed by 250 ml toluene and the mixture was stirred for 10-15 minutes. The aqueous and organic layers were separated, then the aqueous layer was extracted with (2*75 ml) toluene. The combined organic layer was washed with (3×75 ml) water and then subjected to distillation to obtain a thick residue. The residue was dissolved in 150 ml of acetone followed by adding of 12.5 g oxalic acid and 200 ml of isopropyl ether and the mixture was stirred for 1-1.5 hours at 0-50C, then the obtained solid was separated by filtration and washed with isopropyl ether (100 ml) resulting in the (+/-)-atomoxetine oxalate with yield 62.4% and a purity of 95.4 area-% by HPLC.

The chemical industry reduces the impact on the environment during synthesis 42142-52-9, I believe this compound will play a more active role in future production and life.

Reference:
Patent; DR. REDDY’S LABORATORIES LTD.; DR. REDDY’S LABORATORIES, INC.; WO2006/37055; (2006); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts