Category: 4074-88-8

ToF-SIMS and Machine Learning for Single-Pixel Molecular Discrimination of an Acrylate Polymer Microarray was written by Gardner, Wil;Hook, Andrew L.;Alexander, Morgan R.;Ballabio, Davide;Cutts, Suzanne M.;Muir, Benjamin W.;Pigram, Paul J.. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2020.Related Products of 4074-88-8 This article mentions the following:

Combinatorial approaches to materials discovery offer promising potential for the rapid development of novel polymer systems. Polymer microarrays enable the high-throughput comparison of material phys. and chem. properties-such as surface chem. and properties like cell attachment or protein adsorption-in order to identify correlations that can progress materials development. A challenge for this approach is to accurately discriminate between highly similar polymer chemistries or identify heterogeneities within individual polymer spots. Time-of-flight secondary ion mass spectrometry (ToF-SIMS) offers unique potential in this regard, capable of describing the chem. associated with the outermost layer of a sample with high spatial resolution and chem. sensitivity. However, this comes at the cost of generating large scale, complex hyperspectral imaging data sets. We have demonstrated previously that machine learning is a powerful tool for interpreting ToF-SIMS images, describing a method for color-tagging the output of a self-organizing map (SOM). This reduces the entire hyperspectral data set to a single reconstructed color similarity map, in which the spectral similarity between pixels is represented by color similarity in the map. Here, we apply the same methodol. to a ToF-SIMS image of a printed polymer microarray for the first time. We report complete, single-pixel mol. discrimination of the 70 unique homopolymer spots on the array while also identifying intraspot heterogeneities thought to be related to intermixing of the polymer and the pHEMA coating. In this way, we show that the SOM can identify layers of similarity and clusters in the data, both with respect to polymer backbone structures and their individual side groups. Finally, we relate the output of the SOM anal. with fluorescence data from polymer-protein adsorption studies, highlighting how polymer performance can be visualized within the context of the global topol. of the data set. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Related Products of 4074-88-8).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Related Products of 4074-88-8

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Severe bullous allergic contact dermatitis caused by glycidyl methacrylate and other acrylates was written by Vogel, Tatiana Alexandra;Christoffers, Wietske Andrea;Engfeldt, Malin;Bruze, Magnus;Coenraads, Pieter-Jan;Schuttelaar, Marie-Louise Anna. And the article was included in Contact Dermatitis in 2014.Product Details of 4074-88-8 This article mentions the following:

A research illustrates a rarer case of a severe allergic contact dermatitis caused by acrylates glycidyl methacrylate and 1,6 hexanediol diacrylate in an occupational setting. The multiple reactivity to various acrylates in this patient can be explained by two different phenomena: cross-reactivity, and sub sequent exposure to other acrylates. This case report reveals the importance of patch testing with a dilution series of acrylates to distinguish between a contact allergy and an irritant reaction. And moreover, it emphasizes the importance of investigating the products in a patient’s workplace and testing the purity of these products. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Product Details of 4074-88-8).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Product Details of 4074-88-8

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In vitro and in vivo biocompatibility of novel zwitterionic poly(beta amino)ester hydrogels based on diacrylate and glycine for site-specific controlled drug release was written by Filipovic, Vuk V.;Babic, Marija M.;Godevac, Dejan;Pavic, Aleksandar;Nikodinovic-Runic, Jasmina;Tomic, Simonida Lj.. And the article was included in Macromolecular Chemistry and Physics in 2019.Reference of 4074-88-8 This article mentions the following:

New (β-aminoester) hydrogels (PBAE) based on di(ethylene glycol)diacrylate and glycine are successfully synthesized and characterized for the first time in this work. PBAE macromers are obtained using Michael addition By changing the diacrylate/amine stoichiometric ratio, but maintaining it >1, samples with different chem. structure containing acrylate end-groups are obtained. The hydrogels are synthesized from macromers utilizing free radical polymerization Chem. structure of macromers and hydrogels is confirmed by proton NMR, and Fourier transform infra-red spectroscopy. Swelling and degradation rates in physiol. pH range change notably with pH and monomer molar ratio, validating pH sensitivity and zwitterionic behavior, which can be finely tuned by changing any of these parameters. In vitro cytotoxicity and in vivo acute embryotoxicity in zebrafish (Danio rerio) performed to assess the biocompatibility of the novel hydrogel materials and their degradation products reveal that materials are nontoxic and biocompatible. The Cephalexin in vitro drug release study, at pH values 2.20, 5.50, and 7.40, demonstrates pH-sensitive delivery with the release profiles effectively controlled by pH and the hydrogel composition PBAE hydrogels exhibit great potential for a variety of biomedical applications, including tissue regeneration and intelligent drug delivery systems. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Reference of 4074-88-8).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Reference of 4074-88-8

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In situ monitoring of photo-crosslinking reaction of water-soluble bifunctional macromers using magnetic levitation was written by Ashkarran, Ali Akbar;Sharifi, Shahriar;Abrahamsson, Christoffer K.;Mahmoudi, Morteza. And the article was included in Analytica Chimica Acta in 2022.Category: alcohols-buliding-blocks This article mentions the following:

Crosslinking is one of the fundamental phenomena in polymer science, which happens by forming covalent bonds or relatively short sequences of chem. bonds to join 2 polymer chains. Crosslinking and the subsequent volume shrinkage of monomers/macromers result in changes in their corresponding d. which can be measured using d.-based measurement techniques (e.g., dilatometry). Here, the authors demonstrate a method that allows in situ monitoring of photopolymerization of H₂O-soluble bifunctional macromers using magnetic levitation (MagLev) system. The authors use a hydrophobic paramagnetic solution to monitor the photopolymerization of H₂O-soluble polyethylene glycol diacrylate (PEGDA) as a model of bifunctional macromers using a ring MagLev system. Based on changes in levitation heights (densities) after illumination of blue light, the authors have successfully monitored the double bond conversion of PEGDA 700 macromers at various polymerization conditions. Probably MagLev can should be used as a new and complementary anal. technique for rapid screening of the photopolymerization reactions and measurement of conversions using changes in the levitation height of the macromers. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Category: alcohols-buliding-blocks).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

An imidazolium-based ionene blended with crosslinked PEO as a novel polymer membrane for selective CO₂ separation was written by Kammakakam, Irshad;Rao, Anil H. N.;Yoon, Hee Wook;Nam, SangYong;Park, Ho Bum;Kim, Tae-Hyun. And the article was included in Macromolecular Research in 2014.Product Details of 4074-88-8 This article mentions the following:

A novel imidazolium-based ionene was mixed with a di(ethylene glycol) diacrylate that was subsequently photocrosslinked to form a blend membrane useful for CO₂/N₂ gas separation The crosslinked poly(ethylene oxide) (PEO) offered a mech. stable matrix with a high CO₂ affinity. The ionene loading affected both the structure and CO₂ separation performance of the blend membranes as demonstrated by varying the ionene content in three levels, 1:1, 2:1, and 3:1 (ionene:crosslinker) by weight The CO₂ solubility of the membrane dramatically increased with the ionene loading level, and a high CO₂/N₂ permselectivity of 33.5 was obtained for the [3II-cPEO][TFSI]. The imidazolium-based ionene blend membranes prepared with crosslinked PEO (II-cPEO) also displayed good thermal and mech. stability. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Product Details of 4074-88-8).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Product Details of 4074-88-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

High toughness of blood compatible polymer and 3D printing was written by Asai, Fumio;Nagoya, Chembio. And the article was included in Kobunshi in 2022.Quality Control of Diethyleneglycoldiacrylate This article mentions the following:

In Japan today, the era of 100-yr life expectancy is fast approaching as the average life expectancy of the Japanese people increases year by year. Realization of new therapeutic techniques in the medical field is indispensable for the formation of a healthy and long-lived society, and research and development of medical polymer materials that can meet unmet medical needs is important. Against this background, in this study, we combined different materials, i.e., polymers and Japanese inorganic particles, to create medical polymer with self-adhesive properties for the realization of small-diameter artificial blood vessels. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Quality Control of Diethyleneglycoldiacrylate).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Quality Control of Diethyleneglycoldiacrylate

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Regulation of mechanical properties of diene rubber cured by oxa-Michael Reaction via manipulating network structure was written by Zhang, Xuhui;Tang, Zhenghai;Guo, Baochun. And the article was included in Polymer in 2018.Recommanded Product: 4074-88-8 This article mentions the following:

As diene rubber products are generally fabricated with complicated curing package involving toxic additives, the exploration of alternative green curing chem. for diene rubber is of great importance. In this contribution, we demonstrate a curing chem. based on oxa-Michael reaction for diene rubber to achieve the combination of simple curing system and tunable mech. properties. Specifically, pendent hydroxyls are introduced onto the solution-polymerized styrene-butadiene rubber (SSBR) via thiol-ene click reaction and the modified SSBR is effectively cured by various acrylates without the use of any addnl. additives. The mech. behaviors of vulcanizates can be widely regulated by manipulating the network structures, which is tuned by curing temperature, hydroxyl content of SSBR, content and functionality of acrylates. The correlation between mech. properties and network structure is accordingly achieved, which provides essential basis for the future application of the diene rubbers cured by oxa-Michael reaction. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Recommanded Product: 4074-88-8).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 4074-88-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Acrylate and methacrylate contact allergy and allergic contact disease: a 13-year review was written by Spencer, Ashley;Gazzani, Paul;Thompson, Donna A.. And the article was included in Contact Dermatitis in 2016.Application of 4074-88-8 This article mentions the following:

Summary : Background : (Meth)acrylates are important causes of contact allergy and allergic contact disease, such as dermatitis and stomatitis, with new and emerging sources resulting in changing clin. presentations. Objectives : To identify the (meth)acrylates that most commonly cause allergic contact disease, highlight their usefulness for screening, and examine their relationship with occupational and clin. data. Methods : A retrospective review of results from patch tests performed between July 2002 and Sept. 2015, in one tertiary Cutaneous Allergy Unit, was performed Results : A series of 28 (meth)acrylates was applied to 475 patients. Results were pos. in 52 cases, with occupational sources being identified in 24. Industrial exposures and acrylic nails were responsible for 13 and 10 cases, resp., with wound dressings being implicated in 7. We found that four individual (meth)acrylates (2-hydroxyethyl acrylate, 2-hydroxypropyl methacrylate, bisphenol A glycerolate dimethacrylate, and Et acrylate), if used as a screening tool, could have identified 47 (90.4%) of our pos. cases. Conclusions : Our 13-yr experience indicates a changing landscape of (meth)acrylate contact allergy and allergic contact disease, with an observed shift in exposures away from manufacturing and towards acrylic nail sources. Wound dressings are highlighted as emerging sources of sensitization. Larger studies are required to establish the sensitivity and specificity of the four (meth)acrylates proposed for potential screening. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Application of 4074-88-8).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application of 4074-88-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of organic sulfobetaine-based polymer gel electrolyte for dye-sensitized solar cell application was written by Tarannum, Nazia;Varishetty, Madhu Mohan. And the article was included in Polymers for Advanced Technologies in 2017.Application In Synthesis of Diethyleneglycoldiacrylate This article mentions the following:

The authors synthesized eco-friendly, economic, and equally efficient polysulfobetaine-based gel electrolyte to the alternative of liquid electrolyte in the fabrication of dye-sensitized solar cells (DSSCs) for the 1st time. This N-rich and highly conductive polysulfobetaine was synthesized by an easy and facile method without the use of any catalyst and explored for its DSSC application. The synthesized polymer gel electrolyte exhibited good ionic conductivity ∼6.8 × 10^-3 S cm^-1 at ambient temperatures DSSCs were fabricated based on this polysulfobetaine gel electrolyte and studied for their performance based on photovoltaic parameters. The DSSC photovoltaic results were appreciable and are Voc = 0.82 V, Jsc = 11.49 mA/cm², FF = 66%, and PCE = 6.26% at 1 sun intensity. These values are slightly lower than conventional liquid electrolyte-based DSSC shown as Voc = 0.78 V, Jsc = 12.90 mA/cm², FF = 69%, and PCE = 7.07%, both at 100 mW cm^-2. Conductivity and photovoltaic parameters of the device reveals that as prepared polysulfobetaine-based polymer gel electrolyte may be useful in the fabrication of DSSC and other electrochem. devices. Copyright © 2017 John Wiley and Sons, Ltd. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Application In Synthesis of Diethyleneglycoldiacrylate).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of Diethyleneglycoldiacrylate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Photopolymer resins for luminescent three-dimensional printing was written by Wang, Fei;Chong, Yiting;Wang, Fu Ke;He, Chaobin. And the article was included in Journal of Applied Polymer Science in 2017.Application of 4074-88-8 This article mentions the following:

Liquid resins based three-dimensional (3D) printing techniques such as stereolithog. (SLA) and digital light processing (DLP) show higher resolution and accuracy than other printing techniques, but their applications were impeded by the limited materials selection and lack of functions. We here reported the preparation of luminescent resins for DLP-based 3D printing. Homogeneous dispersion of the fluorescent dyes was achieved by small acrylate mols. screening, and the cure depth studies was used to optimize both resin composition and printing parameters setting. In addition, we showed that the optical anal. of absorption and emission spectra is an important tool to reduce the complex mutual-interference of the light absorption of dye, photoinitiator and photo-absorber in the printable resin. We also developed the mater batch technique to tune the emitting colors in the whole visible range, together with white emitting. By using the developed resins, different 3D structures with different emitting colors were successfully printed by DLP technique. These results will further widen the applications of the liquid resins-based 3D printing techniques, and these luminescent resins show highly potential applications in education, lighting, UV converters, and so on. © 2017 Wiley Periodicals, Inc.J. Appl. Polym. Sci. 2017, 134, 44988. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Application of 4074-88-8).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application of 4074-88-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts