Category: 4064-06-6

Zhang, Yunqin; He, Haiqing; Chen, Zixi; Huang, Yingying; Xiang, Guisheng; Li, Penghua; Yang, Xingkuan; Lu, Gang; Xiao, Guozhi published the artcile< Merging Reagent Modulation and Remote Anchimeric Assistance for Glycosylation: Highly Stereoselective Synthesis of α-Glycans up to a 30-mer>, SDS of cas: 4064-06-6, the main research area is branched oligosaccharide preparation glycosylation reagent modulation anchimeric assistance; 1,2-cis glycosylation; reagent modulation; remote anchimeric assistance; structure elucidation; synthetic methods.

The efficient synthesis of long, branched, and complex carbohydrates containing multiple 1,2-cis glycosidic linkages is a long-standing challenge. Here, we report a merging reagent modulation and 6-O-levulinoyl remote anchimeric assistance glycosylation strategy, which is successfully applied to the first highly stereoselective synthesis of the branched Dendrobium Huoshanense glycans and the linear Longan glycans containing up to 30 contiguous 1,2-cis glucosidic bonds. DFT calculations shed light on the origin of the much higher stereoselectivities of 1,2-cis glucosylation with 6-O-levulinoyl group than 6-O-acetyl or 6-O-benzoyl groups. Orthogonal one-pot glycosylation strategy based on glycosyl ortho-alkynylbenzoates and ortho-(1-phenylvinyl)benzoates has been demonstrated in the efficient synthesis of complex glycans, precluding such issues as aglycon transfer inherent to orthogonal one-pot synthesis based on thioglycosides.

Angewandte Chemie, International Edition published new progress about Dendrobium catenatum. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, SDS of cas: 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Koruyucu, Meryem; Saltan, Fehmi; Kok, Gokhan; Akat, Hakan; Salman, Yesim published the artcile< Novel sugar based acrylate: synthesis, characterization and polymerization>, HPLC of Formula: 4064-06-6, the main research area is novel sugar based acrylate synthesis polymerization.

The present study has demonstrated that novel acrylic glycopolymers are successfully prepared by using monosaccharides containing an acrylate group (9-12). For this purpose, sugar based acrylate monomers were synthesized via ring opening method (Method B) and homopolymerization of this sugar oxypropylacrylates was performed using free radical polymerization The characterization of all the monomers and polymers were verified by 1HNMR, 13CNMR, FTIR and GPC techniques. The Glass transition temperatures and thermal characteristics of the polymers were also analyzed by using DSC and TG techniques. The thermal stability of prepared polymers have changed with the stereochem. of the carbohydrate moiety. Also, the mol. weight of the polymers has affected the thermal stability.

Journal of Polymer Materials published new progress about Glass transition temperature. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, HPLC of Formula: 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Dong; von Krbek, Larissa K. S.; Yu, Le; Ronson, Tanya K.; Thoburn, John D.; Carpenter, John P.; Greenfield, Jake L.; Howe, Duncan J.; Wu, Biao; Nitschke, Jonathan R. published the artcile< Glucose Binding Drives Reconfiguration of a Dynamic Library of Urea-Containing Metal-Organic Assemblies>, Application In Synthesis of 4064-06-6, the main research area is iron urea functionalized ditopic formylpyridine helicate preparation crystal structure; host guest binding activity inclusion iron helicate saccharide mutarotation; dynamic combinatorial library; glucose binding; host-guest systems; metal-organic assemblies; supramolecular chemistry.

A bis-urea-functionalized ditopic subcomponent assembled with 2-formylpyridine and FeII, resulting in a dynamic library of metal-organic assemblies: an irregular FeII4L6 structure and three FeII2L3 stereoisomers: left- and right-handed helicates and a meso-structure. This library reconfigured in response to the addition of monosaccharide derivatives, which served as guests for specific library members, and the rate of saccharide mutarotation was also enhanced by the library. The (P) enantiomer of the FeII2L3 helical structure bound β-D-glucose selectively over α-D-glucose. As a consequence, the library collapsed into the (P)-FeII2L3 helicate following glucose addition The α-D-glucose was likewise transformed into the β-D-anomer during equilibration and binding. Thus, β-D-glucose and (P)-3 amplified each other in the product mixture, as metal-organic and saccharide libraries geared together into a single equilibrating system.

Angewandte Chemie, International Edition published new progress about Crystal structure. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Application In Synthesis of 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Schuh, Lukas; Mueller, Philipp; Torvisco, Ana; Stueger, Harald; Wrodnigg, Tanja M.; Haas, Michael published the artcile< Synthesis of D-Galactose-Substituted Acylsilanes and Acylgermanes. Model Compounds for Visible Light Photoinitiators with Intriguing High Solubility>, SDS of cas: 4064-06-6, the main research area is photocatalyst acylgermane acylsilane synthesis galactose glycoside preparation; acylgermane acylsilane synthesis galactose crystal structure photoinitiator crystal structure.

A convenient synthetic method to obtain D-galactose-substituted acylsilanes and acylgermanes is described. These acyl group 14 compounds are easily accessible in good yields. Their structural properties were analyzed by a combination of NMR, single crystal X-ray crystallog., and UV/vis spectroscopy. A D-galactose-substituted tetra-acylgermane represents a new interesting visible light photoinitiator based on its absorption properties as well as its high solubility

Organometallics published new progress about Crystal structure. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, SDS of cas: 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wei, Ruohan; Liu, Han; Tang, Arthur H.; Payne, Richard J.; Li, Xuechen published the artcile< A Solution to Chemical Pseudaminylation via a Bimodal Glycosyl Donor for Highly Stereocontrolled α- and β-Glycosylation>, Synthetic Route of 4064-06-6, the main research area is stereoselective glycosylation pseudaminic acid bimodal glycoside donor.

A robust methodol. for the stereocontrolled chem. glycosylation of pseudaminic acid has been developed to afford both α- (axial) and β- (equatorial) glycosides reliably with complete stereoselectivity, using a common glycosyl donor (7N-Cbz/5N-azido Pse thioglycoside) simply by changing the reaction conditions. In the CH2Cl2/MeCN cosolvent, highly β-selective pseudaminylation was observed, while addition of 5.0 equiv DMF in CH2Cl2 gave the α-pseudaminosides.

Organic Letters published new progress about Glycosides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Synthetic Route of 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nizamov, Ilyas S.; Shumatbaev, Georgiy G.; Nizamov, Ilnar D.; Nikitin, Yevgeniy N.; Belov, Timur G.; Shulaeva, Marina P.; Pozdeev, Oscar K.; Batyeva, Elvira S.; Cherkasov, Rafael A. published the artcile< Chiral methylbenzylammonium salts of aryldithiophosphonic acids containing glucofuranose, allofuranose, and galactopyranose diacetonide scaffolds>, Formula: C12H20O6, the main research area is methylbenzylammonium aryldithiophosphonic acid glucofuranose allofuranose galactopyranose diacetonide antibacterial antimicrobial.

New chiral methylbenzylammonium salts of aryldithiophosphonic acids containing glucofuranose, allofuranose, and galactopyranose diacetonide substituents were obtained using (S)-(-)-α-methylbenzylamine, (R)-(+)-α-methylbenzylamine, and (R,S)-(±)-α-methylbenzylamine. Salts obtained possess antimicrobial activity.

Phosphorus, Sulfur and Silicon and the Related Elements published new progress about Antibacterial agents. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Formula: C12H20O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ghosh, Titli; Mukherji, Ananya; Kancharla, Pavan K. published the artcile< Open-Close Strategy toward the Organocatalytic Generation of 2-Deoxyribosyl Oxocarbenium Ions: Pyrrolidine-Salt-Catalyzed Synthesis of 2-Deoxyribofuranosides>, Formula: C12H20O6, the main research area is stereoselective glycosylation catalyst organocatalytic disaccharide preparation; organocatalytic deoxyribosyl oxocarbenium pyrrolidine catalyzed synthesis disaccharide deoxyribofuranoside.

The reaction of secondary amine salts with 2-deoxy-ribofuranoses under forcible conditions leads to the putative furanosyl oxocarbenium ion that is trapped with various alcs. to provide 2-deoxy-ribofuranosides. The observed anomeric selectivities range from an equimolar mixture to complete α-selectivity in the case of bulky sugar acceptors. Owing to the mechanism and temperature of the transformation, the generated oxocarbenium ion shows little or no facial preference towards the nucleophilic attack of non-carbohydrate acceptors and leads to a mixture of anomers in the case of benzyl and acetyl protected donors. However, the conformationally less flexible tetraisopropylsilyl protected donor reacted with both sugar and non-sugar acceptors in a stereoselective fashion. Besides, the glycosylation with 2-cyanoethanol gave the product with unexpected beta-selectivity presumably due to nitrile effect. The operationally simple organocatalytic protocol provides easy access to otherwise difficult 2-deoxy-ribofuranosides/disaccharides.

European Journal of Organic Chemistry published new progress about Disaccharides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Formula: C12H20O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhou, Si-Yu; Hu, Xin-Ping; Liu, Hui-Juan; Zhang, Qing-Ju; Liao, Jin-Xi; Tu, Yuan-Hong; Sun, Jian-Song published the artcile< 8-(Methyltosylaminoethynyl)-1-naphthyl (MTAEN) Glycosides: Potent Donors in Glycosides Synthesis>, Electric Literature of 4064-06-6, the main research area is crystal structure oligosaccharide synthesis glycosylation glycoside; phase transfer catalysis oligosaccharide synthesis MTAEN methyltosylaminoethynylnaphthyl glycosylation glycoside.

With 8-(methyltosylaminoethynyl)-1-naphthyl (MTAEN) glycoside as donors, a novel and efficient glycosylation protocol has been established. The MTAEN glycosylation protocol exhibits the merits of shelf-stable donors, mild catalytic promotion conditions, considerably extended substrate scope encompassing both free alcs., silylated alcs., nucleobases, primary amides, and C-type nucleophile acceptors, and applicability to various one-pot strategies for highly efficient synthesis of oligosaccharides, such as orthogonal one-pot, single-catalyst one-pot, and acceptor reactivity-controlled one-pot strategies.

Organic Letters published new progress about Catalysis. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Electric Literature of 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pal, Kumar Bhaskar; Guo, Aoxin; Das, Mrinmoy; Bati, Gabor; Liu, Xue-Wei published the artcile< Superbase-Catalyzed Stereo- and Regioselective Glycosylation with 2-Nitroglycals: Facile Access to 2-Amino-2-deoxy-O-glycosides>, SDS of cas: 4064-06-6, the main research area is aminoglycoside regioselective stereoselective glycosylation catalyst DFT glycoconjugate nitroglucal aminodeoxyglycoside.

An efficient super-base-catalyzed stereo- and regioselective glycosylation of 2-nitroglycals with high functional group compatibility is reported. The ion pair generated from alc. and a catalytic amount of P4-t-Bu was vital for the successful implementation of this stereoselective glycosylation under mild conditions, producing moderate to good yields. Under reported reaction conditions, 2-nitrogalactals produce α-stereoisomers exclusively, while 2-nitroglucal yielded more β-products. The notable difference between the outcomes was investigated by the d. functional theory (DFT) study. In addition, we have synthesized the key intermediate of a mucin-type core-6 glycoconjugate, thus illustrating the synthetic potency of this method.

ACS Catalysis published new progress about Aminoglycosides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, SDS of cas: 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mukherji, Ananya; Kancharla, Pavan K. published the artcile< C-H···Anion Interactions Assisted Addition of Water to Glycals by Sterically Hindered 2,4,6-Tri-tert-butylpyridinium Hydrochloride>, Quality Control of 4064-06-6, the main research area is pyridinium hydrochloride catalyst stereoselective hydroxylation glycoside preparation glycal; crystal structure steric effect silyl hemiacetal disaccharide glycosylation glycoside.

The conjugate acid of the bulky base 2,4,6-tri-tert-butylpyridine, under mild conditions, catalyzes the synthesis of silyl-protected 2-deoxy-hemiacetals and their dimerized products from glycals at varying concentrations of water. The criticality of the concentration of water in the reaction outcome is indicative of a unique mechanistic pathway for the bulky pyridine salt and not via the general Bronsted acid mechanism. The various silyl-protected hemiacetals thus synthesized were successfully utilized in the stereoselective synthesis of both α and β glycosides.

Organic Letters published new progress about Crystal structure. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Quality Control of 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts