Category: 4048-33-3

Song, Liya; Chen, Pengfei; Yu, Jin; Han, Xiaolu; Hua, Yabing; Liu, Shan; Pang, Bo; Gao, Jing; Ma, Jiahua; Xu, Liang published their research in Journal of Materials Chemistry B: Materials for Biology and Medicine in 2021. The article was titled 《A novel cyanoacrylate-based matrix excipient in HPMCP capsules forms a sustained intestinal delivery system for orally administered drugs with enhanced absorption efficiency》.HPLC of Formula: 4048-33-3 The article contains the following contents:

Patients prefer oral drug delivery due to its convenience and noninvasiveness. Nevertheless, a multitude of potentially clin. important drugs will not reach the market or achieve their full potential, due to their low bioavailability and instability in gastric acid. In this study, a novel oral drug delivery system based on poly-cyanoacrylate [a polymer of 2-(2-methoxyethoxy)ethyl-2-cyanoacrylate (MECA)] and hydroxypropyl methylcellulose phthalate (HPMCP) was developed and shown to permit intestinal targeting and sustained drug release. Aspirin [acetylsalicylic acid (ASA)] was selected as a model drug for atherosclerosis treatment. It was phys. dissolved in liquid MECA, and the ASA-MECA matrix was then polymerized into a solid drug-loading depot in an HPMCP shell. The delivery of the drug depot in the intestine was achieved with the HPMCP shell; then the polymerized MECA (polyMECA) provided sustained drug release. The polyMECA excipient was not absorbed by the intestine due to its high mol. weight; a fluorescein-labeled assay indicated that it was excreted completely in feces after drug release. The formulation, ASA-polyMECA-HPMCP, showed good intestinal targeting and sustained drug release in vitro and in vivo. Pharmacokinetic studies indicated that this formulation improved the bioavailability of ASA relative to com. available controls. ASA-polyMECA-HPMCP showed desirable anti-atherosclerosis efficacy in a rabbit model, with significant enhancement of atheromatous lesion stability. Biosafety tests proved the low toxicity of ASA-polyMECA-HPMCP and the polyMECA matrix. We believe that this work has provided a practical and biocompatible system for sustained intestinal drug delivery that can be applied broadly with various drugs for specific therapeutic aims.6-Aminohexan-1-ol(cas: 4048-33-3HPLC of Formula: 4048-33-3) was used in this study.

6-Aminohexan-1-ol(cas: 4048-33-3) may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties. It can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine.HPLC of Formula: 4048-33-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《New perylenebisimide decorated cyclotriphosphazene heavy atom free conjugate as singlet oxygen generator》 were Okutan, Elif; Eserci, Hande; Senkuytu, Elif. And the article was published in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2019. Recommanded Product: 6-Aminohexan-1-ol The author mentioned the following in the article:

Perylenebisimide-cyclotriphosphazene based inorganic-organic system was synthesized by a multistep procedure. The substitution reaction of asym. perylenebisimide (PBI) derivative with the hexachloroyclotriphosphazene (trimer) resulted in the formation of fully PBI decorated cyclotriphosphazene (5). The identity of newly synthesized compound (5) was confirmed by using 31P, 1H and 13C NMR spectroscopies and mass spectrometry. The photophys. (UV- Vis absorption, fluorescence emission, fluorescence lifetime and fluorescence quantum yield) and photochem. (the singlet oxygen generation, and photostability) properties of this conjugate were investigated as novel heavy atom free triplet photosensitizer. The singlet oxygen quantum yield of the PBI-cyclotriphosphazene (5) was calculated to be 0.86 which is good for a heavy atom free triplet photosensitizer. These results will add to the development of cyclotriphosphazene based heavy atom free singlet oxygen triplet photosensitizer systems for applications in organic oxygenation reactions.6-Aminohexan-1-ol(cas: 4048-33-3Recommanded Product: 6-Aminohexan-1-ol) was used in this study.

6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Recommanded Product: 6-Aminohexan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application of 4048-33-3In 2022 ,《POSS-containing polynorbornene with pendant perylene diimide: from a unique supramolecular structure to tunable luminescence properties》 appeared in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices. The author of the article were Liu, Jie; Gao, Si-Yu; Zhang, Xin-Yi; Feng, Yakai; Wu, Han-Chun; Chen, Zhijian; Bermeshev, Maxim V.; Ren, Xiang-Kui. The article conveys some information:

POSS-containing polynorbornene with pendant perylene diimide (PPDI-POSS) has been synthesized, with alkyl-containing polynorbornene (PPDI-C10C8) as the reference The supermol. structure and photoluminescence properties were elucidated using UV-Vis absorption spectra, and one- and two-dimensional X-ray diffraction. The exptl. results reveal that PPDI-C10C8 possesses a lamellar structure with close PDI stacking to meet the requirement for min. free energy. However, the introduction of POSS cages endows PPDI-POSS with a unique hexagonal columnar structure and enhanced photoluminescence properties due to the steric hindrance of POSS cages. These results may contribute to the understanding of the structure-property relationship of the optical polymers and provide some useful information for the design of polymer materials with a controllable supramol. structure and tunable luminescence properties. In the experimental materials used by the author, we found 6-Aminohexan-1-ol(cas: 4048-33-3Application of 4048-33-3)

6-Aminohexan-1-ol(cas: 4048-33-3) can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.Application of 4048-33-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Spectroscopic characterization and antimicrobial activity of nanoparticle doped cyclodextrin polyurethane bionanosponge》 was published in Materials Science & Engineering, C: Materials for Biological Applications in 2020. These research results belong to Leudjo Taka, Anny; Doyle, Bryan P.; Carleschi, Emanuela; Youmbi Fonkui, Thierry; Erasmus, Rudolph; Fosso-Kankeu, Elvis; Pillay, Kriveshini; Mbianda, Xavier Y.. Application In Synthesis of 6-Aminohexan-1-ol The article mentions the following:

This study reports on the spectroscopic characterization and antimicrobial potency of polyurethane cyclodextrin co-polymerized phosphorylated multiwalled carbon nanotube-doped Ag-TiO2 nanoparticle (pMWCNT-CD/Ag-TiO2) bionanosponge nanocomposite. The synthesis of pMWCNT-CD/Ag-TiO2 bionanosponge nanocomposite was carried out through the combined processes of amidation and polymerization reactions as well as the sol-gel method. The native nanosponge cyclodextrin and phosphorylated multiwalled carbon nanotube-nanosponge CD (pMWCNT-CD) polyurethanes were also prepared, and their antimicrobial activities carried out for comparison purposes. The potency tests of the synthesized compounds were carried out against three bacterial strains Escherichia coli, Bacillus subtilis, Staphylococcus aureus, and two fungal representatives Aspergillus ochraceus and Aspergillus fumigatus, using the disk diffusion method. Micro dilution and agar plating were used to determine the min. bactericidal concentration (MBC) and min. fungicidal concentration (MFC), resp. The results obtained revealed that pMWCNT-CD/Ag-TiO2 exhibits superior antibacterial and antifungal activities when compared to the other bionanosponge polymers tested. Thus, the bionanosponge polyurethane pMWCNT-CD/Ag-TiO2 nanocomposite can be considered as an active antimicrobial compound (AMC). In addition to this study using 6-Aminohexan-1-ol, there are many other studies that have used 6-Aminohexan-1-ol(cas: 4048-33-3Application In Synthesis of 6-Aminohexan-1-ol) was used in this study.

6-Aminohexan-1-ol(cas: 4048-33-3) may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties. It can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine.Application In Synthesis of 6-Aminohexan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts