Category: 403-41-8

Waiba, Satyadeep; Jana, Sayan K.; Jati, Ayan; Jana, Akash; Maji, Biplab published the artcile< Manganese complex-catalysed α-alkylation of ketones with secondary alcohols enables the synthesis of β-branched carbonyl compounds>, Computed Properties of 403-41-8, the main research area is aryl ketone secondary alc manganese complex alkylation; carbonyl compound preparation.

Herein, β-branched carbonyl compounds were synthesized via the α-alkylation of ketones with secondary alcs. under “”borrowing hydrogen”” catalysis. A wide range of secondary alcs., including various cyclic, acyclic, sym., and unsym. alcs., was successfully applied under the developed reaction conditions. A manganese(I) complex bearing a phosphine-free multifunctional ligand catalyzed the reaction and produced water as the sole byproduct.

Chemical Communications (Cambridge, United Kingdom) published new progress about Alkylation. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Computed Properties of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cabeza, Javier A.; Fernandez-Colinas, Jose M.; Garcia-Alvarez, Joaquin; Garcia-Alvarez, Pablo; Laglera-Gandara, Carlos J.; Ramos-Martin, Marina published the artcile< Dipyrromethane-Based PGeP Pincer Germyl Rhodium Complexes>, SDS of cas: 403-41-8, the main research area is crystal structure mol dipyrromethane pincer germyl rhodium complex preparation; dipyrromethane pincer germyl rhodium complex hydroboration catalyst styrene catecholborane; PGeP pincers; germylenes; hydroboration; pincer complexes; rhodium.

A family of germyl rhodium complexes derived from the PGeP germylene 2,2′-bis(di-isopropylphosphinylmethyl)-5,5′-dimethyldipyrromethane-1,1′-diylgermanium(II), Ge(pyrmPiPr2)2CMe2 (1), has been prepared Germylene 1 reacted readily with [RhCl(PPh3)3] and [RhCl(cod)(PPh3)] (cod=1,5-cyclooctadiene) to give, in both cases, the PGeP-pincer chloridogermyl rhodium(I) derivative [Rh{κ3P,Ge,P-GeCl(pyrmPiPr2)2CMe2}(PPh3)] (2). Similarly, the reaction of 1 with [RhCl(cod)(MeCN)] afforded [Rh{κ3P,Ge,P-GeCl(pyrmPiPr2)2CMe2}(MeCN)] (3). The methoxidogermyl and methylgermyl rhodium(I) complexes [Rh{κ3P,Ge,P-GeR(pyrmPiPr2)2CMe2}(PPh3)] (R=OMe, 4; Me, 5) were prepared by treating complex 2 with LiOMe and LiMe, resp. Complex 5 readily reacted with CO to give the carbonyl rhodium(I) derivative [Rh{κ3P,Ge,P-GeR(pyrmPiPr2)2CMe2}(CO)] (6), with HCl, HSnPh3 and Ph2S2 rendering the pentacoordinate methylgermyl rhodium(III) complexes [RhHX{κ3P,Ge,P-GeMe(pyrmPiPr2)2CMe2}] (X=Cl, 7; SnPh3, 8) and [Rh(SPh)2{κ3P,Ge,P-GeMe(pyrmPiPr2)2CMe2}] (9), resp., and with H2 to give the hexacoordinate derivative [RhH2{κ3P,Ge,P-GeMe(pyrmPiPr2)2CMe2}(PPh3)] (10). Complexes 3 and 5 are catalyst precursors for the hydroboration of styrene, 4-vinyltoluene and 4-vinylfluorobenzene with catecholborane under mild conditions.

Chemistry – A European Journal published new progress about Crystal structure. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, SDS of cas: 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tsui, Brian T. H.; Sung, Molly M. H.; Kinas, Jenny; Hahn, F. Ekkehardt; Morris, Robert H. published the artcile< A Ruthenium Protic N-Heterocyclic Carbene Complex as a Precatalyst for the Efficient Transfer Hydrogenation of Aryl Ketones>, Reference of 403-41-8, the main research area is bipyridinylimidazolylidene ruthenium pincer complex preparation catalyst reduction aryl ketone; crystal structure bipyridinylimidazolylidene ruthenium pincer complex; mol structure bipyridinylimidazolylidene ruthenium pincer complex.

A neutral azole precursor to a protic N-heterocyclic carbene (pNHC) ligand, 6-((4,5-diphenyl-1H-imidazol-1-yl)methyl)-2,2′-bipyridine (3), was prepared from 6-(bromomethyl)-2,2′-bipyridine (2) and 4,5-diphenylimidazole. [RuCl(pNHC-bpy)(PPh3)2](PF6) (4) bearing a protic, bipyridine-tethered NHC ligand was prepared by refluxing 3 with RuCl2(PPh3)3 and KPF6 in MeOH and was characterized by NMR spectroscopy, mass spectrometry, elemental anal., and a single-crystal x-ray diffraction study. The hydrido complex [RuH(pNHC-bpy)(PPh3)2](PF6) (5) was prepared by reaction of 4 with NaBH4 in EtOH and characterized by NMR and FTIR spectroscopy. Complex 5 was used as the catalyst (0.1 mol % loading) in the transfer hydrogenation of a range of alkyl/aryl ketones in basic iso-PrOH at 60°. Bulky alkyl groups or ortho-substituted aryl groups at the ketones slowed down or inhibited the catalytic transformation. The addition of an excess of PPh3 also slowed the catalysis, providing an indication for a mechanism involving phosphine dissociation, while the addition of an excess of elemental Hg had only a small effect on the conversion. The importance of K cations in the mechanism is consistent with the observation of reduced catalytic conversion when [2,2,2]-cryptand was present or when 1,8-diazabicyclo[5.4.0]undec-7-ene was used as the base. A plausible homogeneous catalysis mechanism involving the innersphere addition of hydride to the substrate in the transition state TS1 is supported by d. functional theory calculations where the K ion has replaced the H atom of the N-H group in a protic NHC.

Organometallics published new progress about Alkylidenes Role: CAT (Catalyst Use), PEP (Physical, Engineering or Chemical Process), PRP (Properties), SPN (Synthetic Preparation), USES (Uses), PROC (Process), PREP (Preparation) (Ru pincer complexes). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Reference of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

K. Bains, Amreen; Ankit, Yadav; Adhikari, Debashis published the artcile< Bioinspired Radical-Mediated Transition-Metal-Free Synthesis of N-Heterocycles under Visible Light>, Safety of 1-(4-Fluorophenyl)ethyl Alcohol, the main research area is nitrogen heterocycle preparation; alc oxidation pyrene iminoquinone photocatalyst; amidine alc oxidation pyrene iminoquinone photocatalyst; carbonyl compound preparation; biomimetic catalysis; hydrogen atom transfer; pyrimidine; quinoline; topaquinone.

A redox-active iminoquinone motif connected with π-delocalized pyrene core has been reported that can perform efficient two-electron oxidation of a class of substrates. The design of the mol. was inspired by the organic redox cofactor topaquinone (TPQ), which executes amine oxidation in the enzyme, copper amine oxidase. Easy oxidation of both primary and secondary alcs. such as benzylalc., hexanol, 1-phenylethan-1-ol, cyclohexanol, etc. happened in the presence of catalytic KOtBu, which could reduce the ligand backbone to its iminosemiquinonate form under photoinduced conditions. Moreover, this easy oxidation of alcs. under aerobic condition could be elegantly extended to multi-component, one-pot coupling for the synthesis of quinolines e.g., I and pyrimidines II (R1 = Ph, 2-methylphenyl, 1-naphthyl, etc.; R2 = Ph, 4-chlorophenyl, 2-thienyl, etc.; R3 = H, Cl, Me, Br, etc.). This organocatalytic approach is very mild (70°C, 8 h) compared to a multitude of transition-metal catalysts that have been used to prepare these heterocycles e.g., I and II. A detailed mechanistic study proves the intermediacy of the iminosemiquinonate-type radical and a critical hydrogen atom transfer step to be involved in the dehydrogenation reaction.

ChemSusChem published new progress about Alcohols Role: PRP (Properties), RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Safety of 1-(4-Fluorophenyl)ethyl Alcohol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Rongzhou; Han, Xingyou; Xu, Jing; Liu, Peng; Li, Feng published the artcile< Transfer Hydrogenation of Ketones and Imines with Methanol under Base-Free Conditions Catalyzed by an Anionic Metal-Ligand Bifunctional Iridium Catalyst>, HPLC of Formula: 403-41-8, the main research area is transfer hydrogenation ketone imine methanol; anionic metal ligand bifunctional iridium catalyst transfer hydrogenation.

An anionic iridium complex [Cp*Ir(2,2′-bpyO)(OH)][Na] was found to be a general and highly efficient catalyst for transfer hydrogenation of ketones and imines with methanol under base-free conditions. Readily reducible or labile substituents, such as nitro, cyano, and ester groups, were tolerated under present reaction conditions. Notably, this study exhibits the unique potential of anionic metal-ligand bifunctional iridium catalysts for transfer hydrogenation with methanol as a hydrogen source.

Journal of Organic Chemistry published new progress about Imines Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, HPLC of Formula: 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Maji, Milan; Kundu, Sabuj published the artcile< Cooperative ruthenium complex catalyzed multicomponent synthesis of pyrimidines>, Computed Properties of 403-41-8, the main research area is ruthenium complex catalyst multicomponent preparation pyrimidine.

A new set of 2-(2-benzimidazolyl) pyridine ligand based air and moisture stable ruthenium complexes were synthesized and characterized. The catalytic behaviors of these complexes were evaluated towards the multicomponent synthesis of highly substituted pyrimidines directly from various amidines, primary alcs., and secondary alcs. Among all the metal complexes, 2-hydroxypyridine and benzimidazole fragments containing complex I showed the best reactivity in this reaction. In addition, the N-H proton of benzimidazole and the hydroxyl group of pyridine played a critical role in enhancing catalytic activity. Several control experiments and mechanistic studies were carried out to understand this multicomponent synthesis of pyrimidines using complex I.

Dalton Transactions published new progress about Amidines Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Computed Properties of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jin, Bei; Wang, Jinguo; Xu, Fengxia; Li, Dianfeng; Men, Yong published the artcile< Hierarchical hollow WO3 microspheres with tailored surface oxygen vacancies for boosting photocatalytic selective conversion of biomass-derived alcohols>, Category: alcohols-buliding-blocks, the main research area is ierarchical hollow WO3 microspheres tailored surface oxygen vacancies; photocatalytic selective conversion biomass derived alc.

Selective conversion of biomass-derived alcs. into carbonyl compounds via visible-light photocatalysis is realized over hierarchical hollow WO3 microspheres with tailored surface oxygen vacancies, which presents the remarkably boosted photoactivity in terms of selectivity and activity, intrinsically attributing to the strong synergetic effect of hierarchical spherical cavity and surface oxygen vacancies simultaneously. The hierarchical spherical cavity, substantially constructed by the self-interconnected nanosheets, enhances the light-harvesting ability via multiple light reflections not only in spherical cavity but also among the self-interconnected nanosheets. Surface oxygen vacancies favor the energy band gap narrowing via forming a miniband just below the conduction band and then extend the photoresponse region, further boosting the light-harvesting ability. Importantly, surface oxygen vacancies function as the electron sinks to capture photoelectrons and thus restrict their recombination probability with holes, finally improving the photoelectron-hole separation efficiency. Meanwhile, this photocatalyst presents excellent reusability, showing its promising potential in practical applications. This work sheds light on a new application of hierarchical WO3 microspheres with tailored surface oxygen vacancies and its strong synergetic effect of hierarchical structures and surface oxygen vacancies on photocatalytic performance, delivering new insights for rationally designing highly active photocatalysts applied in future green and sustainable organic transformation reactions.

Applied Surface Science published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent) (biomass-derived). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Jiahao; Li, Weikang; Li, Yinwu; Liu, Yan; Ke, Zhuofeng published the artcile< Selective C-alkylation between Alcohols Catalyzed by N-Heterocyclic Carbene Molybdenum>, Reference of 403-41-8, the main research area is primary secondary alc molybdenum complex alkylation chemoselectivity green chem; secondary alc preparation; Alcohols; Alkylation; Borrowing hydrogen; Molybdenum catalysis; N-heterocyclic carbene.

The implementation of a molybdenum complex with an easily accessible bis-N-heterocyclic carbene ligand to catalyze β-alkylation of secondary alcs. via borrowing-hydrogen (BH) strategy using alcs. as alkylating agents was reported. Remarkably high activity, excellent selectivity and broad substrate scope compatibility with advantages of catalyst usage low to 0.5 mol%, a catalytic amount of NaOH as the base and H2O as the byproduct were demonstrated in this green and step-economical protocol. Mechanistic studies indicated a plausible outer-sphere mechanism in which the alc. dehydrogenation is the rate-determining step.

Chemistry – An Asian Journal published new progress about Alkylation catalysts (chemoselective). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Reference of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nandi, Pran Gobinda; Kumar, Pradhuman; Kumar, Akshai published the artcile< Ligand-free Guerbet-type reactions in air catalyzed by in situ formed complexes of base metal salt cobaltous chloride>, Related Products of 403-41-8, the main research area is phenyl ethanol benzyl alc Guerbet type reaction green chem; cobaltous chloride complex catalyst.

Inexpensive, earth-abundant and environmentally benign cobaltous chloride efficiently accomplishes the catalytic β-alkylation of alcs. in air at 140°. At higher loadings of cobaltous chloride (1 mol%) in the presence of 2.5 mol% NaOtBu, there is a rapid formation of heterogeneous Co nanoparticles (NPs) which are apparently sensitive to air and result in poor yields (ca. 25%) of β-alkylated products. In contrast, performing the reaction in an argon atm. under otherwise identical conditions leads to higher yields (ca. 44%). The heterogenization and eventual loss of activity in air could be delayed by operating at a lower (0.01 mol%) CoCl2 loading in the presence of 2.5 mol% NaOtBu at 140°. Under these conditions, the catalytic β-alkylation of alcs. proceeded with high yields (up to 89%) and unprecedented turnovers (ca. 8900). Mechanistic studies are indicative of the involvement of catalysts based on in situ generated mol. Co complexes of alcs. Labeling studies provide key evidence for the involvement of C-H activation in the cobaltous chloride catalyzed β-alkylation with a KIE of 1.61. Kinetic studies indicate linear dependence of the rate on the concentration of cobaltous chloride and sodium t-butoxide along with a non-linear dependence on the concentration of 1-Ph ethanol and benzyl alc.

Catalysis Science & Technology published new progress about Alkylation. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Related Products of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Luo, Huihui; Wang, Lianyue; Shang, Sensen; Li, Guosong; Lv, Ying; Gao, Shuang; Dai, Wen published the artcile< Cobalt Nanoparticles-Catalyzed Widely Applicable Successive C-C Bond Cleavage in Alcohols to Access Esters>, COA of Formula: C8H9FO, the main research area is ester preparation cobalt nanoparticle catalyst carbon bond cleavage alc; C−C bond; aerobic oxidative cleavage; alcohols; esters; heterogeneous cobalt catalyst.

Selective cleavage and functionalization of C-C bonds have important applications in organic synthesis and biomass use. However, functionalization of C-C bonds by controlled cleavage remains difficult and challenging because they are inert. Herein, the authors describe an unprecedented efficient protocol for the breaking of successive C-C bonds in alcs. to form esters with one or multiple carbon atoms less using heterogeneous cobalt nanoparticles as catalyst with dioxygen as the oxidant. A wide range of alcs. including inactive long-chain alkyl aryl alcs. undergo smoothly successive cleavage of adjacent -(C-C)n- bonds to afford the corresponding esters. The catalyst was used for seven times without any decrease in activity. Characterization and control experiments disclose that cobalt nanoparticles are responsible for the successive cleavage of C-C bonds to achieve excellent catalytic activity, while the presence of Co-Nx has just the opposite effect. Preliminary mechanistic studies reveal that a tandem sequence reaction is involved in this process.

Angewandte Chemie, International Edition published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, COA of Formula: C8H9FO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts