Category: 403-41-8

Zhang, Guoqi; Wu, Jing; Zheng, Shengping; Neary, Michelle C.; Mao, Jincheng; Flores, Marco; Trovitch, Ryan J.; Dub, Pavel A. published the artcile< Redox-Noninnocent Ligand-Supported Vanadium Catalysts for the Chemoselective Reduction of C=X (X = O, N) Functionalities>, Reference of 403-41-8, the main research area is vanadium ligand catalyst reduction ketone aldehyde imine ester carboxamide.

Catalysis is the second largest application for V after its use as an additive to improve steel production Mol. complexes of vanadium(V) are particularly useful and efficient catalysts for oxidation processes; however, their ability to catalyze reductive transformations has yet to be fully explored. Here the authors report the first examples of polar organic functionality reduction mediated by V. Open-shell VIII complexes that feature a π-radical monoanionic 2,2′:6′,2”-terpyridine ligand (Rtpy•)- functionalized at the 4′-position (R = (CH3)3SiCH2, Ph) catalyze mild and chemoselective hydroboration and hydrosilylation of functionalized ketones, aldehydes, imines, esters, and carboxamides with turnover numbers (TONs) of up to ∼1000 and turnover frequencies (TOFs) of up to ∼500 h-1. Computational evaluation of the precatalyst synthesis and activation revealed underappreciated complexity associated with the redox-active tpy chelate.

Journal of the American Chemical Society published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Reference of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Vielhaber, Thomas; Faust, Kirill; Topf, Christoph published the artcile< Group 6 Metal Carbonyl Complexes Supported by a Bidentate PN Ligand: Syntheses, Characterization, and Catalytic Hydrogenation Activity>, HPLC of Formula: 403-41-8, the main research area is phosphinoethylamino chromium carbonyl complex preparation catalyst hydrogenation benzaldehyde; molybdenum phosphinoethylamino carbonyl complex preparation catalyst hydrogenation benzaldehyde; tungsten phosphinoethylamino carbonyl complex preparation catalyst hydrogenation benzaldehyde; crystal structure phosphinoethylamino chromium molybdenum tungsten carbonyl complex; mol structure phosphinoethylamino chromium molybdenum tungsten carbonyl complex.

The authors report on the preparation of P-N donor ligand complexes [M(CO)4(PN)], where M = Cr, Mo, W and PN is 2-(diphenylphosphino)ethylamine. The organometallic compounds were readily obtained upon reacting the resp. metal hexacarbonyls with equimolar amounts of the pertinent ligand in the presence of Et4NBr. The PN-ligated metal carbonyls were fully characterized by standard spectroscopic techniques and x-ray crystallog. The ability of the title compounds to function as homogeneous hydrogenation catalysts was probed in the reduction of acetophenone and benzaldehyde derivatives to yield the corresponding alcs. The reaction setup was easily assembled by simply combining the components in the autoclave on the bench outside an inert-gas-operated glovebox system.

Organometallics published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, HPLC of Formula: 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Qu, Peiyuan; Kuepfert, Michael; Jockusch, Steffen; Weck, Marcus published the artcile< Compartmentalized Nanoreactors for One-Pot Redox-Driven Transformations>, Product Details of C8H9FO, the main research area is micellar compartmentalized nanoreactor catalyst preparation redox deracemization secondary alc; polyoxazoline synthesis nanoreactor.

This contribution introduces poly(2-oxazoline)-based shell cross-linked micelles (SCMs) as nanoreactors to realize one-pot redox-driven deracemizations of secondary alcs. in aqueous media. TEMPO and Rh-TsDPEN moieties are spatially positioned into the hydrophilic corona and the hydrophobic micelle core, resp. TEMPO catalyzes the oxidation of racemic secondary alcs. into ketones, while Rh-TsDPEN catalyzes the asym. transfer hydrogenation (ATH) of these ketones to afford enantioenriched secondary alcs. Both catalysts, the Rh-TsDPEN complex and TEMPO, are incompatible with each other and the SCMs are designed to provide indispensable catalyst site isolation. Kinetic studies show that the SCMs enhance the reactivity of the immobilized catalysts, in comparison to those for the unsupported analogs under the same reaction conditions. Our nanoreactors can perform deracemizations on a broad range of secondary alc. substrates and are reusable in a continuous manner while maintaining high activity.

ACS Catalysis published new progress about ESR (electron spin resonance). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Product Details of C8H9FO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lan, Xiao-Bing; Ye, Zongren; Liu, Jiahao; Huang, Ming; Shao, Youxiang; Cai, Xiang; Liu, Yan; Ke, Zhuofeng published the artcile< Sustainable and Selective Alkylation of Deactivated Secondary Alcohols to Ketones by Non-bifunctional Pincer N-heterocyclic Carbene Manganese>, Electric Literature of 403-41-8, the main research area is ketone preparation green chem; primary secondary alc alkylation heterocyclic carbene manganese catalyst; N-heterocyclic carbene; alkylation; borrowing hydrogen; manganese; pincer.

A sustainable and green route to access diverse functionalized ketones RC(O)CH2CH2R1 (R = Ph, thiophen-2-yl, 4-bromophenyl, etc.; R1 = Ph, naphthalen-2-yl, pyridin-3-yl, etc.) via dehydrogenative-dehydrative cross-coupling of primary R1CH2OH and secondary alcs. RCH(OH)CH3 is demonstrated. This borrowing hydrogen approach employing a pincer N-heterocyclic carbene Mn complex I•Br- (R2 = Me, iPr, Ph) displays high activity and selectivity. A variety of primary and secondary alcs. is well tolerant and results in satisfactory isolated yields. Mechanistic studies suggest that this reaction proceeds via a direct outer-sphere mechanism and the dehydrogenation of the secondary alc. substrates plays a vital role in the rate-limiting step.

ChemSusChem published new progress about Alkylation. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Electric Literature of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Guo, Bin; Yu, Tian-Qi; Li, Hong-Xi; Zhang, Shi-Qi; Braunstein, Pierre; Young, David J.; Li, Hai-Yan; Lang, Jian-Ping published the artcile< Phosphine Ligand-Free Ruthenium Complexes as Efficient Catalysts for the Synthesis of Quinolines and Pyridines by Acceptorless Dehydrogenative Coupling Reactions>, Name: 1-(4-Fluorophenyl)ethyl Alcohol, the main research area is quinoline preparation green chem; aminobenzyl secondary alc dehydrogenative coupling ruthenium complex catalyst; pyridine preparation green chem; amino secondary alc dehydrogenative coupling ruthenium complex catalyst.

A series of phosphine-free Ru(III)/Ru(II) complexes of NH functionalized N N N pincer ligands exhibit excellent activity for acceptorless dehydrogenative coupling (ADC) of secondary alcs. RCH(OH)CH2R1 [R = Ph, thiophen-2-yl, Et, etc.; R1 = H, Me, Et, n-Pr; RR1 = -(CH2)4-] and bicyclo[2.2.1]heptan-2-ol with 2-aminobenzyl 2-NH2-R3C6H3CH(R2)OH [R2 = H, Me; R3 = H, 5-Me, 4-Cl] or γ-amino alcs. R4CH(NH2)(CH2)2OH (R4 = Ph, Me) to quinolines I (R5 = H, 6-Me, 7-Cl), 1,2,3,4-tetrahydro-1,4-methanoacridine and pyridines II. Ru(III) complexes [LRuCl3] III (R6 = R7 = R8 = H, R9 = Cl; R6 = H, R7 = R8 = Me, R9 = Cl; R6 = R7 = H, R8 = Ph, R9 = Cl, etc.) were obtained by refluxing RuCl3.xH2O with the corresponding ligand in EtOH. Five Ru(II) complexes [LRu(DMSO-κS)Cl2] III [R9 = S(CH3)2(O)] were formed by reducing the corresponding Ru(III) complex in refluxing EtOH. The latter complexes could also be prepared directly by refluxing Ru(DMSO)4Cl2 with the corresponding ligand in EtOH. These Ru(III) and Ru(II) complexes, especially III exhibited high catalytic efficiency and broad functional group tolerance in ADC reactions of secondary alcs. with 2-aminobenzyl or γ-amino alcs. to quinolines I and pyridines II. A detail mechanistic study indicated that the Ru(III) complex III (R9 = Cl) was reduced into the Ru(II) species III (R9 = S(CH3)2(O)), which was the active catalytic center for ADC via a Ru-H/N-H bifunctional outer-sphere mechanism. This protocol provides a reliable, atom-economical and environmentally benign procedure for C-N and C-C bond formation.

ChemCatChem published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Name: 1-(4-Fluorophenyl)ethyl Alcohol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Budweg, Svenja; Junge, Kathrin; Beller, Matthias published the artcile< Transfer-dehydrogenation of secondary alcohols catalyzed by manganese NNN-pincer complexes>, Reference of 403-41-8, the main research area is manganese pincer complex preparation crystal structure; secondary alc manganese pincer complex catalyst transfer dehydrogenation; ketone preparation.

Novel catalytic systems based on pentacarbonylmanganese bromide and stable NNN-pincer ligands were presented for the transfer-dehydrogenation of secondary alcs. to gave the corresponding ketones in good to excellent isolated yields. Best results were obtained using di-picolylamine derivatives as ligands and acetone as an inexpensive hydrogen acceptor. Besides high activity for benzylic substrates, aliphatic alcs., as well as steroid derivatives, were readily oxidized in the presence of the optimal phosphorus-free catalyst.

Chemical Communications (Cambridge, United Kingdom) published new progress about Crystal structure. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Reference of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chevella, Durgaiah; Macharla, Arun Kumar; Kodumuri, Srujana; Banothu, Rammurthy; Gajula, Krishna Sai; Amrutham, Vasu; Gennadievna, Grigor’eva Nellya; Nama, Narender published the artcile< Synthesis of internal olefins by direct coupling of alcohols and olefins over Moβ zeolite>, Formula: C8H9FO, the main research area is reusable molybdenum zeolite preparation thermal stability crystallinity; olefin aryl alc reusable zeolite catalyst dehydrative cross coupling; internal olefin diastereoselective regioselective preparation green chem.

An efficient and novel Moβ zeolite catalyzed sp2-sp3 C-C bond development reaction over the direct coupling of alcs. and alkenes was performed in solvent free environment. The current method gave an attractive access to a wide variety of polysubstituted alkenes in good to excellent yields. The Moβ zeolite was effectively reused for up to 5 successive cycles.

Catalysis Communications published new progress about Acidity. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Formula: C8H9FO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Guoqi; Li, Sihan; Zeng, Haisu; Zheng, Shengping; Neary, Michelle C. published the artcile< Diplumbane-catalysed solvent- and additive-free hydroboration of ketones and aldehydes>, Synthetic Route of 403-41-8, the main research area is alc preparation chemoselective; ketone aldehyde pinacolborane hydroboration diplumbane catalyst.

A new diplumbane, namely [Pb(CH2SiMe3)3]2, was synthesized and structurally characterized. This group 14 element compound was found to catalyze the hydroboration of ketones R1C(O)R2 (R1 = Ph, 4-fluorophenyl, naphthalen-2-yl, pyridin-3-yl, cyclohexyl, etc.; R2 = H, Me, cyclopropyl, 2-phenylethyl) and aldehydes R3CHO (R3 = Ph, 4-chlorophenyl, 2H-1,3-benzodioxol-5-yl, 2-(methylsulfanyl)phenyl, etc.) under mild conditions without the use of additives and solvents, leading to the synthesis of a range of alcs. R1CH(OH)R2/R3CH2OH in high yields after hydrolysis.

RSC Advances published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Synthetic Route of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Zewei; Lv, Kang; Yuan, Taoyue; Zhang, Xuguang; Yao, Weiwei; Ma, Mengtao published the artcile< Electrochemical hydroboration of carbonyl compounds>, Computed Properties of 403-41-8, the main research area is aryl alkyl alc preparation; boronic ester preparation regioselective green chem hydrolysis; carbonyl compound tetramethyl dioxaborolane electrochem hydroboration.

A green and sustainable electrochem. hydroboration of carbonyl compounds RC(O)R1 (R = Bu, Ph, cyclohexyl, pyridin-4-yl, etc.; R1 = H, Me, Ph, i-Pr, 2-fluorophenyl) with HBpin has been reported for the first time. Under catalyst-free and additive-free mild reaction conditions the corresponding boronic esters RR1CHOBpin were obtained in excellent yields via the simple electrochem. hydroboration of various aldehydes and ketones with HBpin at room temperature The scale-up reaction demonstrated potential practical applications. A plausible reaction mechanism was proposed based on the corresponding deuterium-labeling, radical inhibition and cyclic voltammetry experiments

Dalton Transactions published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Computed Properties of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hu, Wenkang; Zhang, Yilin; Zhu, Haiyan; Ye, Dongdong; Wang, Dawei published the artcile< Unsymmetrical triazolylnaphthyridinylpyridine bridged highly active copper complexes supported on reduced graphene oxide and their application in water>, SDS of cas: 403-41-8, the main research area is copper triazolylnaphthyridinylpyridine complex preparation catalyst.

A novel unsym. triazolylnaphthyridinylpyridine ligand was designed and synthesized, and employed in the synthesis of a heterogeneous copper complex on reduced graphene oxide. The resulting copper composite was characterized by SEM, TEM, XPS and energy dispersive x-ray spectroscopy (EDX). This supported copper catalyst containing unsym. triazolylnaphthyridinylpyridine (only 0.1 mol%) showed excellent catalytic activity in water with good recyclability. Various functionalized quinoline derivatives were successfully synthesized in high yields through the green strategy in water. Other heterocyclic compounds, such as pyridine, 2-(pyridin-2-yl)quinoline, 1,8-naphthyridine, 5,6-dihydronaphtho[1,2-b][1,8]naphthyridine and 2-(pyridin-2-yl)-1,8-naphthyridine derivatives, were achieved in water with >80% yields. Mechanism studies revealed that this transformation occurs via dehydrogenation, condensation, and transfer hydrogenation and dehydrogenation processes which was supported by a deuterium labeling experiment

Green Chemistry published new progress about Catalysts. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, SDS of cas: 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts