Category: 403-41-8

Liu, Yaxu; He, Shaopo; Quan, Ziyi; Cai, Huizhuo; Zhao, Yang; Wang, Bo published the artcile< Mild palladium-catalysed highly efficient hydrogenation of CN, C-NO2, and C=O bonds using H2 of 1 atm in H2O>, COA of Formula: C8H9FO, the main research area is amine preparation green chem; nitro compound hydrogenation palladium nanocatalyst; nitrile hydrogenation palladium nanocatalyst; alc preparation green chem; aldehyde hydrogenation palladium nanocatalyst; ketone hydrogenation palladium nanocatalyst.

The first example of a mild and high-efficiency protocol enabling a process in water using 1 atm of H2 for the efficient and selective hydrogenation of nitriles RCN [R = CH3(CH2)2, 4-FC6H4, naphthalen-1-yl, etc.], nitro compounds 4-R1C6H4NO2 (R1 = H, F, Cl, Br, OH, Me, MeO, NH2), ketones R2C(O)R3 [R2 = CH3(CH2)2, 3-FC6H4, 2-H3CC6H4, etc.; R3 = Me, CF3] and aldehydes R4CHO [R4 = 4-(H3C)2CHC6H4, 3,4,5-(H3CO)3C6H2, naphthalen-1-yl, etc.], to yield primary amines RCH2NH2, 4-R1C6H4NH2 and alcs. R2CH(OH)CH3, R4CH2OH with satisfactory yields of up to >99% has been presented. Several palladium-based nanoparticle catalysts were prepared from K2PdCl4 and ligands, and one of them was found to be the best and most suitable for the hydrogenation of CN, C-NO2 and C=O bonds. In addition, the catalyst Pd-NPs can be easily recycled and reused without losing their activity and selectivity. A plausible mechanism for the hydrogenation of a CN bond was also proposed, representing the first example that possesses great potential for sustainable industrial purposes.

Green Chemistry published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, COA of Formula: C8H9FO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nikitas, Nikolaos F.; Tzaras, Dimitrios Ioannis; Triandafillidi, Ierasia; Kokotos, Christoforos G. published the artcile< Photochemical oxidation of benzylic primary and secondary alcohols utilizing air as the oxidant>, Formula: C8H9FO, the main research area is photochem oxidation benzylic secondary alc air oxidant; aldehyde ketone preparation.

A mild and green photochem. protocol for the oxidation of alcs. to aldehydes and ketones was developed. Using thioxanthenone as the photocatalyst, mol. oxygen from air as the oxidant and cheap household lamps or sunlight as the light source, a variety of primary and secondary alcs. were converted into the corresponding aldehydes or ketones in low to excellent yields. The reaction mechanism was extensively studied.

Green Chemistry published new progress about Aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Formula: C8H9FO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhu, Xianjin; Liu, Can; Liu, Yong; Yang, Haijun; Fu, Hua published the artcile< A sodium trifluoromethanesulfinate-mediated photocatalytic strategy for aerobic oxidation of alcohols>, Synthetic Route of 403-41-8, the main research area is ketone carboxylic acid preparation; sodium trifluoromethylsulfinate catalyst photochem aerobic oxidation alc.

A sodium trifluoromethanesulfinate-mediated photocatalytic strategy for the aerobic oxidation of alcs. has been developed for the first time, and the photoredox aerobic oxidation of secondary and primary alcs. provided the corresponding ketones and carboxylic acids, resp., in high to excellent yields.

Chemical Communications (Cambridge, United Kingdom) published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Synthetic Route of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ye, Danfeng; Liu, Zhiyuan; Sessler, Jonathan L.; Lei, Chuanhu published the artcile< Base-free oxidation of alcohols enabled by nickel(II)-catalyzed transfer dehydrogenation>, Related Products of 403-41-8, the main research area is ketone preparation; alc nickel catalyst transfer dehydrogenation oxidation.

An efficient nickel(II)-catalyzed transfer dehydrogenation oxidation of alcs. was reported that relies on cyclohexanone as the formal oxidant and does not require the use of an external base. The synthetic utility of this protocol was demonstrated via the facile oxidation of structurally complicated natural products.

Chemical Communications (Cambridge, United Kingdom) published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Related Products of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Abubakar, Samaila; Bala, Muhammad D. published the artcile< Transfer Hydrogenation of Ketones Catalyzed by Symmetric Imino-N-heterocyclic Carbene Co(III) Complexes>, Electric Literature of 403-41-8, the main research area is ketone imino NHC cobalt transfer hydrogenation catalyst; alc preparation.

The synthesis of new moisture-sensitive imine-functionalized N-heterocyclic carbene (NHC) precursor salts [1-(2-[(hydroxyl-benzylidene)-amino]-ethyl)-3-R-3H-imidazole-1-ium bromide; R = Me, Et, and benzyl] is reported. Subsequent deprotonation of precursor and coordination of the in situ generated NHC ligands to CoBr2 led to the isolation of air-stable six-coordinate Co(III) complexes, resp. All the salts and complexes were fully characterized. Single-crystal X-ray anal. of Co(III) complexes showed octahedral Co centers hexacoordinated to two NHC carbons, two imine nitrogen atoms, and two phenolate oxygens in the form [C~NÕ(Co3+)CÑÕ]. The complexes were used in the catalytic transfer hydrogenation (CTH) of a range of ketones in 2-propanol as the solvent and hydrogen donor. Based on a low catalyst concentration of 0.4 mol %, significant conversions in the range of 70-99% were recorded at high turnover frequencies up to 1635 h-1. A mechanism to account for the steps involved in the CTH of cyclohexanone by complex is proposed and supported by data from cyclic voltammetry, low-resolution mass spectrometry, UV, and IR spectroscopic techniques.

ACS Omega published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Electric Literature of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bains, Amreen K.; Singh, Vikramjeet; Adhikari, Debashis published the artcile< Homogeneous Nickel-Catalyzed Sustainable Synthesis of Quinoline and Quinoxaline under Aerobic Conditions>, Related Products of 403-41-8, the main research area is amine alc nickel catalyst dehydrogenative coupling green; quinoline preparation; quinoxaline preparation.

Dehydrogenative coupling-based reactions have emerged as an efficient route toward the synthesis of a plethora of heterocyclic rings. Herein, we report an efficacious, nickel-catalyzed synthesis of two important heterocycles such as quinoline and quinoxaline. The catalyst is molecularly defined, is phosphine-free, and can operate at a mild reaction temperature of 80°C. Both the heterocycles can be easily assembled via double dehydrogenative coupling, starting from 2-aminobenzyl alc./1-phenylethanol and diamine/diol, resp., in a shorter span of reaction time. This environmentally benign synthetic protocol employing an inexpensive catalyst can rival many other transition-metal systems that have been developed for the fabrication of two putative heterocycles. Mechanistically, the dehydrogenation of secondary alc. follows clean pseudo-first-order kinetics and exhibits a sizable kinetic isotope effect. Intriguingly, this catalyst provides an example of storing the trapped hydrogen in the ligand backbone, avoiding metal-hydride formation. Easy regeneration of the oxidized form of the catalyst under aerobic/O2 oxidation makes this protocol eco-friendly and easy to handle.

Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Related Products of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Martinez-Ferrate, Oriol; Chatterjee, Basujit; Werle, Christophe; Leitner, Walter published the artcile< Hydrosilylation of carbonyl and carboxyl groups catalysed by Mn(I) complexes bearing triazole ligands>, Recommanded Product: 1-(4-Fluorophenyl)ethyl Alcohol, the main research area is alc preparation; ketone ester carboxyl hydrosilylation manganese triazole ligand catalyst.

Manganese(I) complexes bearing triazole ligands are reported as catalysts for the hydrosilylation of carbonyl and carboxyl compounds The desired reaction proceeds readily at 80° within 3 h at catalyst loadings as low as 0.25 to 1 mol%. Hence, good to excellent yields of alcs. could be obtained for a wide range of substrates including ketones, esters, and carboxylic acids illustrating the versatility of the metal/ligand combination.

Catalysis Science & Technology published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Recommanded Product: 1-(4-Fluorophenyl)ethyl Alcohol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kaithal, Akash; van Bonn, Pit; Hoelscher, Markus; Leitner, Walter published the artcile< Manganese(I)-Catalyzed β-Methylation of Alcohols using Methanol as C1 Source>, Synthetic Route of 403-41-8, the main research area is manganese catalyzed methylation biomass alc methanol solvent safety; alcohols; hydrogen borrowing; manganese catalysis; methanol; methylation.

Highly selective β-methylation of alcs. was achieved using an earth-abundant first row transition metal in the air stable mol. manganese complex [Mn(CO)2Br[HN(C2H4PiPr2)2]] (I) ([HN(C2H4PiPr2)2]=MACHO-iPr). The reaction requires only low loadings of I (0.5 mol %), methanolate as base and MeOH as methylation reagent as well as solvent. Various alcs. were β-methylated with very good selectivity (>99%) and excellent yield (up to 94%). Biomass derived aliphatic alcs. and diols were also selectively methylated on the β-position, opening a pathway to “”biohybrid”” mols. constructed entirely from non-fossil carbon. Mechanistic studies indicate that the reaction proceeds through a borrowing hydrogen pathway involving metal-ligand cooperation at the Mn-pincer complex. This transformation provides a convenient, economical, and environmentally benign pathway for the selective C-C bond formation with potential applications for the preparation of advanced biofuels, fine chems., and biol. active mols. Of note, safety advice is recommended for high-pressure experiments due to significant risk with procedures and in conjunction with the use of suitable equipment.

Angewandte Chemie, International Edition published new progress about Alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (biomass). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Synthetic Route of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sahoo, Rajata Kumar; Mahato, Mamata; Jana, Achintya; Nembenna, Sharanappa published the artcile< Zinc Hydride-Catalyzed Hydrofuntionalization of Ketones>, SDS of cas: 403-41-8, the main research area is zinc guanidinate hydride catalyst hydrosilylation hydroboration ketone.

Three new dimeric bis-guanidinate zinc(II) alkyl, halide, and hydride complexes [LZnEt]2 (1), [LZnI]2 (2) and [LZnH]2 (3) (I – III, resp., R = 2,6-Et2C6H3 ) were prepared Compound 3 was successfully employed for the hydrosilylation and hydroboration of a vast number of ketones. The catalytic performance of 3 in the hydroboration of acetophenone exhibits a turnover frequency, reaching up to 5800 h-1, outperforming that of reported zinc hydride catalysts. Notably, both intra- and intermol. chemoselective hydrosilylation and hydroboration reactions have been investigated.

Journal of Organic Chemistry published new progress about Alkoxysilanes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, SDS of cas: 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Luo, Jiabin; Cui, Chuanguo; Xiao, Zhiyin; Zhong, Wei; Lu, Chunxin; Jiang, Xiujuan; Li, Xueming; Liu, Xiaoming published the artcile< Iron(0) tricarbonyl η4-1-azadiene complexes and their catalytic performance in the hydroboration of ketones, aldehydes and aldimines via a non-iron hydride pathway>, Product Details of C8H9FO, the main research area is iron tricarbonyl azadiene hydroboration catalyst ketone aldehyde aldimine mechanism; crystal structure mol iron tricarbonyl azadiene complex preparation protonation.

Six iron(0) tricarbonyl complexes (1a-f) with a η4-1-azadiene moiety were prepared and their performance in the hydroboration of unsaturated organic compounds was investigated. All the complexes exhibit catalytic activity towards hydroboration of ketones, aldehydes and aldimines with pinacolborane (HBpin) as a hydride source to lead to secondary alcs., primary alcs., and secondary amines, resp., after hydrolysis of the hydroboration products. Of the iron(0) tricarbonyl complexes, complex 1e is the most robust one and was employed throughout the catalytic investigation. Its preference towards the three types of substrates is as follows: aldimines > aldehydes ≫ ketones. In total, 24 substrates were examined for the catalytic hydroboration reactivity and generally, isolation yields ranging from 40% to 95% were achieved. Mechanistic investigation suggests that the catalytic hydroboration of the substrates proceeds via intramol. hydride transfer without going through an Fe-H intermediate. As indicated by 1H NMR spectroscopic monitoring, the substrates and the borane agent bind to the iron center and the imine N atom, resp., which facilitates the hydride transfer by activating the B-H bond and polarizing the double bond of the substrates.

Dalton Transactions published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Product Details of C8H9FO.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts