Category: 38584-37-1

Adding a certain compound to certain chemical reactions, such as: 38584-37-1, 3-(Hydroxymethyl)adamantan-1-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Safety of 3-(Hydroxymethyl)adamantan-1-ol, blongs to alcohols-buliding-blocks compound. Safety of 3-(Hydroxymethyl)adamantan-1-ol

(2) 1.0 Part of 1,1′-carbonyldiimidazol was added to a mixture of 1.9 parts of sodium difluorosulfoacetate (purity: 62.7%) and 9.5 parts of N,N-dimethylformamide, and the added mixture was stirred for 2 hours to obtain solution (referred to as solution A). 0.2 Part of sodium hydride was added to a mixture of 1.1 parts of 3-hydroxyadamantylmethanol and 5.5 parts of N,N-dimethylfomamide, and the added mixture was stirred for 2 hours to obtain solution (referred to as solution B). The solution A was added to the solution B, and the mixture was stirred for 15 hours to obtain sodium salt of 3-hydroxy-1-adamantylmethyl difluorosulfoacetate solution. The sodium salt of 3-hydroxy-1-adamantylmethyl difluorosulfoacetate solution was used for the next step without further separation or purification.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,38584-37-1, 3-(Hydroxymethyl)adamantan-1-ol, and friends who are interested can also refer to it.

Reference:
Patent; Sumitomo Chemical Company, Limited; US2006/194982; (2006); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Adding a certain compound to certain chemical reactions, such as: 38584-37-1, 3-(Hydroxymethyl)adamantan-1-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Application In Synthesis of 3-(Hydroxymethyl)adamantan-1-ol, blongs to alcohols-buliding-blocks compound. Application In Synthesis of 3-(Hydroxymethyl)adamantan-1-ol

(2) 5.0 Parts of the salt represented by the formula (g), 2.1 parts of (3-hydroxy-1-adamantyl)methanol, 50 parts of toluene and 0.3 part of concentrated sulfuric acid were mixed. The mixture obtained was heated and refluxed for 22 hours. The mixture was cooled, and then, concentrated. To the residue obtained, 90 parts of chloroform was added, and the solution obtained was repeated to wash with an ion-exchanged water until the aqueous layer obtained was neutralized. The organic layer obtained was concentrated and the residue obtained was mixed with 49 parts of ethyl acetate. The resultant mixture was stirred and filtrated to obtain the solid. The solid obtained was dried to obtain 5.4 parts of the salt represented by the above-mentioned formula (b). The 1H-NMR spectrum of the salt obtained was the same as that of the salt obtained in above-mentioned Salt Synthesis Example 1.

The synthetic route of 38584-37-1 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; US2008/86014; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Electric Literature of 38584-37-1 , The common heterocyclic compound, 38584-37-1, name is 3-(Hydroxymethyl)adamantan-1-ol, molecular formula is C11H18O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

(3) Esterification and polymerization A mixture of 1-hydroxy-3-hydroxymethyladamantane (1 mmol), acryloyl chloride (1.2 mols), triethylamine (1.2 mols) and dioxane (10 ml) was stirred at 40C for 3 hours. As a result, 1-hydroxy-3-(acryloyloxymethyl)adamantane of the following formula was obtained (yield 90%).

The synthetic route of 38584-37-1 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Daichel Chemical Industries Ltd; EP1000924; (2000); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 38584-37-1, name is 3-(Hydroxymethyl)adamantan-1-ol. This compound has unique chemical properties. The synthetic route is as follows. COA of Formula: C11H18O2

(2) 100 Parts of toluene, 10.0 parts of sodium salt of difluorosulfoacetic acid (purity: 97.6%), 8.98 parts of (3-hydroxy-1-adamantyl)methanol and 0.3 part of diphenylammonium trifluoromethanesulfonate were mixed. The mixture obtained was heated and refluxed for 36 hours. The mixture was cooled, and then, concentrated. To the residue obtained, 287 parts of acetonitrile was added, and the mixture obtained was stirred and filtrated. The filtrate obtained was concentrated. To the concentrated liquid obtained, 141 parts of tert-butyl methyl ether was added and the resultant mixture was stirred and filtrated to obtain the solid. The solid obtained was dried to obtain 16.7 parts of the salt represented by the above-mentioned formula (a) in the form of white green solid.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 38584-37-1, 3-(Hydroxymethyl)adamantan-1-ol.

Reference:
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; US2008/86014; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts